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DOE OSTI · 1060720

Beyond small-angle x-ray scattering: Exploiting angular correlations

Saldin, D. K.·Poon, H. C.·Shneerson, V. L.·Howells, M.·Chapman, H. N.·Kirian, R. A.·Schmidt, K. E.·Spence, J. H.
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Abstract

We propose a method for determining the projected electron density of an individual molecule from diffraction patterns of many such simultaneously illuminated molecules, randomly oriented about an axis parallel to an incident x-ray beam. We illustrate the idea with a simulation of a structure determination of a K-channel membrane protein in situ.

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59 BASIC BIOLOGICAL SCIENCESX-Ray Scattering Randomly Oriented Molecules

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Saldin, D. K., Poon, H. C., Shneerson, V. L., Howells, M., Chapman, H. N., Kirian, R. A., Schmidt, K. E., Spence, J. H.. 2010-05-07. Beyond small-angle x-ray scattering: Exploiting angular correlations. https://doi.org/10.1103/physrevb.81.174105

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