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At least 487 records · Page 27

Combined Release and Radiation Effects Satellite (CRRES) experiments data collection, analysis, and publication

The Combined Release and Radiation Effects Satellite (CRRES) program experiments data collection, analysis, and publication activities are described. These activities were associated with both the satellite chemical release and a planned Puerto Rico sounding rocket campaign. To coordinate these activities, a working group meeting was organized and conducted.

Long, Terry N.↗

Test chips and ASIC qualification

A test chip set being developed to aid in the qualification of spaceborne Application Specific Integrated Circuits (ASICs) is described. The chip set consists of a process monitor for process parameter verification, a fault chip for yield analysis, a reliability chip for ASIC failure rate analysis, and total ionizing dose and single event upset chips for radiation effect analysis. The test structures contained in these chips are discussed along with representative test results.

Buehler, M. G.↗

A computational approach to the relationship between radiation induced double strand breaks and translocations

A theoretical framework is presented which provides a quantitative analysis of radiation induced translocations between the ab1 oncogene on CH9q34 and a breakpoint cluster region, bcr, on CH 22q11. Such translocations are associated frequently with chronic myelogenous leukemia. The theory is based on the assumption that incorrect or unfaithful rejoining of initial double strand breaks produced concurrently within the 200 kbp intron region upstream of the second abl exon, and the 16.5 kbp region between bcr exon 2 and exon 6 interact with each other, resulting in a fusion gene. for an x-ray dose of 100 Gy, there is good agreement between the theoretical estimate and the one available experimental result. The theory has been extended to provide dose response curves for these types of translocations. These curves are quadratic at low doses and become linear at high doses.

NASA Discipline Radiation Health↗

Surface Heat Load Analysis Due to Plasma Thermal Radiation on Equatorial Port 09

This paper reports calculated surface heat load owing to plasma thermal radiation, which will be applied to the surfaces of Equatorial Port 09 (EP09) diagnostic shield modules (DSMs) for thermal analysis during normal operation. The calculation assumes that the thermal energy will deposit uniformly in all directions from the plasma to the adjacent components and environment (i.e. gray body radiation). Assuming the temperature for the plasma surface, calculated view factors are used to determine the allocation of thermal energy to each component. The analysis provides an initial assessment of the thermal radiation heat load on the DSMs to be checked in structural/thermal analyses to verify significance. In conclusion, the designs of the EP09 components are still in the early preliminary phase, and changes are expected in the future.

ANSYS↗

The Stability of Radiatively Cooling Jets I. Linear Analysis

The results of a spatial stability analysis of a two-dimensional slab jet, in which optically thin radiative cooling is dynamically important, are presented. We study both magnetized and unmagnetized jets at external Mach numbers of 5 and 20. We model the cooling rate by using two different cooling curves: one appropriate to interstellar gas, and the other to photoionized gas of reduced metallicity. Thus, our results will be applicable to both protostellar (Herbig-Haro) jets and optical jets from active galactic nuclei. We present analytical solutions to the dispersion relations in useful limits and solve the dispersion relations numerically over a broad range of perturbation frequencies. We find that the growth rates and wavelengths of the unstable Kelvin-Helmholtz (K-H) modes are significantly different from the adiabatic limit, and that the form of the cooling function strongly affects the results. In particular, if the cooling curve is a steep function of temperature in the neighborhood of the equilibrium state, then the growth of K-H modes is reduced relative to the adiabatic jet. On the other hand, if the cooling curve is a shallow function of temperature, then the growth of K-H modes can be enhanced relative to the adiabatic jet by the increase in cooling relative to heating in overdense regions. Inclusion of a dynamically important magnetic field does not strongly modify the important differences between an adiabatic jet and a cooling jet, provided the jet is highly supermagnetosonic and not magnetic pressure-dominated. In the latter case, the unstable modes behave more like the transmagnetosonic magnetic pressure-dominated adiabatic limit. We also plot fluid displacement surfaces associated with the various waves in a cooling jet in order to predict the structures that might arise in the nonlinear regime. This analysis predicts that low-frequency surface waves and the lowest order body modes will be the most effective at producing observable features in the jet.

Hardee, Philip E.↗

Galaxy formation by dust

It has been known since the early 1940's that radiation can cause an instability in the interstellar medium. Absorbing dust particles in an isotropic radiation field shadow each other by a solid angle which is inversely proportional to the square of the distance between the two particles, leading to an inverse-square attractive force - mock gravity. The effect is largest in an optically thin medium. Recently Hogan and White (HW, hereafter) proposed that if the pre-galactic universe contained suitable sources of radiation and dust, instability in the dust distribution caused by mock gravity may have led to the formation of galaxies and galaxy clusters. In their picture of a well-coupled dust-gas medium, HW show that mock gravity begins to dominate gravitational instability when the perturbation becomes optically thin, provided that the radiation field at the time is strong enough. The recent rocket observation of the microwave background at submillimeter wavelengths by Matsumoto et al. might be from pre-galactic stars, the consequence of the absorption of ultraviolet radiation by dust, and infrared reemission which is subsequently redshifted. HW's analysis omits radiative drag, incomplete collisional coupling of gas and dust, finite dust albedo, and finite matter pressure. These effects could be important. In a preliminary calculation including them, the authors have confirmed that mock gravitational instability is effective if there is a strong ultraviolet radiation at the time, but any galaxies that form would be substantially enriched in heavy elements because the contraction of the dust is more rapid than that of the gas. Moreover, since the dust moves with supersonic velocity through the gas soon after the perturbation becomes optically thin, the sputtering of dust particles by gas is significant, so the dust could disappear before the instability develops significantly. They conclude that the mock gravity by dust is not important in galaxy formations.

Wang, Boqi↗

Radiative Heating Indicators and Uncertainty Analysis for Mars 2020

This paper will present analysis to evaluate a functional form and associated parameters to determine the radiative heating at various back-shell locations of the Mars 2020 aeroshell. The radiative heating indicators are used for preliminary vehicle design, and to determine the worst-case trajectories for peak radiative heat flux and load. Historically, the functional form for radiative heating is based on free-stream parameters of density, velocity and a length scale, typically the nose-radius (or equivalent). However, a fit of this form has been shown to not provide significant enough accuracy when compared to simulation results. Therefore, a fit based on post-shock equilibrium calculations of CO and CO2 number density, temperature and pressure has been devised. The results from the TPS 15 01 trajectory were used to develop the fit. The fit was then applied to the MSL best estimated trajectory (BET). Furthermore, the paper will quantify the uncertainty in simulations of the radiative heating for Mars 2020.

Mars 2020↗

Polar solar wind and interstellar wind properties from interplanetary Lyman-alpha radiation measurements

The analysis of Mariner 10 observations of Lyman-alpha resonance radiation shows an increase of interplanetary neutral hydrogen densities above the solar poles. This increase is caused by a latitudinal variation of the solar wind velocity and/or flux. Using both the Mariner 10 results and other solar wind observations, the values of the solar wind flux and velocity with latitude are determined for several cases of interest. The latitudinal variation of interplanetary hydrogen gas, arising from the solar wind latitudinal variation, is shown to be most pronounced in the inner solar system. From this result it is shown that spacecraft Lyman-alpha observations are more sensitive to the latitudinal anisotropy for a spacecraft location in the inner solar system near the downwind axis.

Witt, N.↗

AIR Model Preflight Analysis

The atmospheric ionizing radiation (AIR) ER-2 preflight analysis, one of the first attempts to obtain a relatively complete measurement set of the high-altitude radiation level environment, is described in this paper. The primary thrust is to characterize the atmospheric radiation and to define dose levels at high-altitude flight. A secondary thrust is to develop and validate dosimetric techniques and monitoring devices for protecting aircrews. With a few chosen routes, we can measure the experimental results and validate the AIR model predictions. Eventually, as more measurements are made, we gain more understanding about the hazardous radiation environment and acquire more confidence in the prediction models.

Tai, H.↗

The Influence of Ablation on Radiative Heating for Earth Entry

Using the coupled ablation and radiation capability recently included in the LAURA flowfield solver, this paper investigates the influence of ablation on the shock-layer radiative heating for Earth entry. The extension of the HARA radiation model, which provides the radiation predictions in LAURA, to treat a gas consisting of the elements C, H, O, and N is discussed. It is shown that the absorption coefficient of air is increased with the introduction of the C and H elements. A simplified shock layer model is studied to show the impact of temperature, as well as the abundance of C and H, on the net absorption or emission from an ablation contaminated boundary layer. It is found that the ablation species reduce the radiative flux in the vacuum ultraviolet, through increased absorption, for all temperatures. However, in the infrared region of the spectrum, the ablation species increase the radiative flux, through strong emission, for temperatures above 3,000 K. Thus, depending on the temperature and abundance of ablation species, the contaminated boundary layer may either provide a net increase or decrease in the radiative flux reaching the wall. To assess the validity of the coupled ablation and radiation LAURA analysis, a previously analyzed Mars-return case (15.24 km/s), which contains significant ablation and radiation coupling, is studied. Exceptional agreement with previous viscous shock-layer results is obtained. A 40% decrease in the radiative flux is predicted for ablation rates equal to 20% of the free-stream mass flux. The Apollo 4 peak-heating case (10.24 km/s) is also studied. For ablation rates up to 3.4% of the free-stream mass flux, the radiative heating is reduced by up to 19%, while the convective heating is reduced by up to 87%. Good agreement with the Apollo 4 radiometer data is obtained by considering absorption in the radiometer cavity. For both the Mars return and the Apollo 4 cases, coupled radiation alone is found to reduce the radiative heating by 30 60% and the convective heating by less than 5%.

Johnston, Christopher O.↗

BLOOD-BASED MULTI-SCALE MODEL FOR CANCER RISK FROM GCR IN GENETICALLY DIVERSE POPULATIONS

OBJECTIVES AND METHODS This project addresses the challenge of understanding and predicting individual radiation sensitivity by integrating genetics, demographics and biomarker characteristics across species (mice and humans). We hypothesize that ex vivo DNA repair response to GCR components is a central determinant of cancer risk from space radiation and can serve as a biomarker of radiation risk in combination with genetics. Automated image quantification of 53BP1+ radiation-induced foci (RIF) during the first 4-48 h post-irradiation was performed as a function of dose and LET in non-immortalized primary skin fibroblasts derived from 76 mice across 15 strains (5 inbred reference strains and 10 collaborative-cross strains) exposed to X rays (0.1, 1 and 4 Gy), 350 MeV/n 40Ar and 600 MeV/n 56Fe (1.1 and 3 particles/100μm2), as well as in peripheral blood mononuclear cells (PBMCs) from 768 healthy donors (matched ethnicity, 50/50 male/female, 18-70 years old) exposed to gamma rays (0.1 and 1 Gy), 350 MeV/n 28Si, 350 MeV/n 40Ar and 600 MeV/n 56Fe (1.1 and 3 particles/100μm2). QUANTIFICATION OF 53BP1+ FOCI IN VITRO AND ASSOCIATIONS TO IN VIVO RADIATION SUSCEPTIBILITY IN 15 MOUSE STRAINS We reported in vitro repair kinetic and repairable fractions of RIF for the 15 mouse strains and introduced a mathematical model for RIF as a function of time, dose and LET. We noted that the metabolic activity of cells modulates the RIF response, and we introduced the open access tool terRIFic (Tool for Enhanced Results of RIF In Cells, https://radbiolab.shinyapps.io/terrific/) to correct for such bias using confluence level. Notably, at 4h post-irradiation, RIF/Gy decreased with dose or LET: as the dose or LET increases, so does the proximity of DNA double-strand-breaks (DSB) and our data suggest that proximal DSBs are brought together inside isolated RIF for repair. The RIF/Gy trend was inverted at 24h, suggesting RIF with high DSB content are more difficult to repair. We showed that in vitro metrics correlate with in vivo measurements in the same 15 mouse strains, such as survival levels of immune cells or spontaneous cancer incidence, suggesting a relationship between the efficiency of DSB repair and cancer risk or radiation toxicity. In addition to the efficiency of repair and persistent RIF, the amount of spontaneous foci before irradiation was also found to be strain dependent. Finally, we performed genome-wide association study in the same 15 mouse strains using all RIF phenotypes measured in vitro, identifying genes of interest and validating RIF as an ideal biomarker for individual radiation sensitivity. BASELINE 53BP1+ FOCI PREDICTS INDIVIDUAL HUMAN RESPONSE TO GCR COMPONENTS Based on the analysis of radiation responses of 576 donor PBMCs (using quantification of 53BP1+ foci, oxidative stress and cell death), we observed a wide variability of subject- and LET-dependent radiation responses, with radiation-induced DNA repair foci increasing with LET, though oxidative stress being notably reduced by high-LET irradiation, potentially due to a switch between hydrogen peroxide and oxygen radical-based mechanisms. We identified a relationship between few spontaneous DNA foci at baseline and increased DNA repair after irradiation, accompanied by an alteration in immunoregulatory cytokine secretion, which might be adapted as biomarkers to predict ionizing radiation sensitivity. Among demographic variables, only latent cytomegalovirus infection and age were predictive of high baseline foci formation. Finally, we have performed low-throughput whole genome sequencing of all samples and are currently in the process of identifying the genes and pathways associated with low and high-LET ionizing radiation sensitivity in humans.

53BP1↗

Analysis of flight effects on noise radiation from jet flow using a convecting quadrupole model

The effects of flight on noise radiation from convecting quadrupoles in a jet flow are examined. The analysis shows that as flight velocity increases there is a steadily increasing amplification of the sound that is radiated into the forward arc and a large reduction of the sound that is radiated into the rearward arc. The analysis also shows the same trend when there is a reduction in the exhaust velocity with, however, a further rise in amplification in the forward quadrant and a drop in attenuation in the aft quadrant. Finally, it is concluded that there is a transmission effect tending to enhance the sound radiation by a density ratio pf/pj which increases with increasing jet temperature.

Dash, R.↗

Radiation Response of Ga 2 O 3 MOSFETs Probed via Focused Particle Beams

Gallium Oxide (Ga 2 O 3 ), particularly in its β-phase, is attracting lots of interest for high-power and high-voltage electronics due to its wide bandgap, high breakdown field, and thermal stability. This study investigates the radiation response of Ga 2 O 3 Metal-Oxide-Semiconductor Field-Effect Transistors (MOSFETs) under Total Ionizing Dose (TID) and Displacement Damage (DD) conditions, which are critical for applications in radiation environments. Utilizing a dual-beam Focused Ion Beam and Scanning Electron Microscope setup, microscale analysis of radiation effects on individual devices is performed. The findings reveal distinct behaviors under TID and DD + TID conditions, with TID leading to threshold voltage shifts due to trapped charges, while DD results in decreased drive current attributed to increased carrier scattering from lattice defects. Notably, it is demonstrated that the TID effect can be mitigated through dynamic threshold voltage adjustments and that the predicted TID from ions calculated by Monte Carlo simulations overestimates actual TID due to unaccounted charge yield effects. In conclusion, this research enhances the understanding of Ga2O3 MOSFETs' performance in harsh radiation environments, providing insights for the design of robust electronic devices for space and nuclear applications.

MOSFET↗

Shock noise features using the SCIPVIS code

The numerical computational supersonic jet plume model SCIPVIS was analyzed in order to determine its effectiveness for predicting the complicated flow structure associated with supersonic shock containing jet plumes. The analysis focused on assessing the applicability of using this code for predicting the broadband shock noise radiation. The analysis was carried out for several exit Mach number cases (including 1.00, 1.41, and 1.99) covering both underexpanded and overexpanded flow conditions. The three primary turbulence closure models incorporated in the SCIPVIS code were utilized for comparisons to measured plume static pressure distributions. Among other results, the prediction of plume static pressures for all three nozzle exit Mach numbers was found to perform exceptionally well when compared with experimental data for both underexpanded and overexpanded cases. Computations performed using this code for calculating the average shock wavelength for the 1.99 exit Mach number case were shown to provide an excellent prediction of the peak frequency for broadband shock noise. The spatial variation of the turbulent kinetic energy was found to be in qualitative agreement with wedge hot-film measurements.

Seiner, J. M.↗