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At least 469 records · Page 26
All sourcesNASA NTRSDOE OSTI
NASA NTRS1990

Ionizing program environment at the Mars surface

The Langley cosmic ray transport code and the Langley nucleon transport code are used to quantify the transport and attenuation of galactic cosmic rays and solar proton flares through the Martian atmosphere. Surface doses are estimated using both a low-density and a high-density carbon dioxide model of the atmosphere which, in the vertical direction, provide a total of 16 g/sq cm and 22 g/sq cm of protection, respectively. At the Mars surface during the solar minimum cycle, a blood-forming organ (BFO) dose-equivalent of 10.5 to 12 rem/yr due to galactic cosmic ray transport and attenuation is calculated. Estimates of the BFO dose-equivalents which would have been incurred at the surface from three large solar flare events are also calculated. Doses are also estimated at altitudes up to 12 km above the Martian surface where the atmosphere will provide less total protection.

Simonsen, Lisa C.↗
NASA NTRS1997

Evaluation of Exposure From a Low Energy X-Ray Device Using Thermoluminescent Dosimeters

The exposure from an electron beam welding device was evaluated using thermoluminescent dosimeters (TLDs). The device generated low energy X-rays which the current dose equivalent conversion algorithm was not designed to evaluate making it necessary to obtain additional information relating to TLD operation at the photon energies encountered with the device. This was accomplished by performing irradiations at the National Institute of Standards and Technology (NIST) using low energy X-ray techniques. The resulting data was used to determine TLD badge response for low energy X-rays and to establish the relationship between TLD element response and the dose equivalent at specific depths in tissue for these photon energies. The new energy/dose equivalent calibration data was used to calculate the shallow and eye dose equivalent of badges exposed to the device.

Edwards, David L.↗
NASA NTRS2010

Calculation of Dose Deposition in Nanovolumes and Simulation of gamma-H2AX Experiments

Monte-Carlo track structure simulations can accurately simulate experimental data: a) Frequency of target hits. b) Dose per event. c) Dose per ion. d) Radial dose. The dose is uniform in micrometers sized voxels; at the nanometer scale, the difference in energy deposition between high and low-LET radiations appears. The calculated 3D distribution of dose voxels, combined with chromosomes simulated by random walk is very similar to the distribution of DSB observed with gamma-H2AX experiments. This is further evidenced by applying a visualization threshold on dose.

Plante, Ianik↗
NASA NTRS2013

Radiation Exposure Analyses Supporting the Development of Solar Particle Event Shielding Technologies

NASA has plans for long duration missions beyond low Earth orbit (LEO). Outside of LEO, large solar particle events (SPEs), which occur sporadically, can deliver a very large dose in a short amount of time. The relatively low proton energies make SPE shielding practical, and the possibility of the occurrence of a large event drives the need for SPE shielding for all deep space missions. The Advanced Exploration Systems (AES) RadWorks Storm Shelter Team was charged with developing minimal mass SPE storm shelter concepts for missions beyond LEO. The concepts developed included "wearable" shields, shelters that could be deployed at the onset of an event, and augmentations to the crew quarters. The radiation transport codes, human body models, and vehicle geometry tools contained in the On-Line Tool for the Assessment of Radiation In Space (OLTARIS) were used to evaluate the protection provided by each concept within a realistic space habitat and provide the concept designers with shield thickness requirements. Several different SPE models were utilized to examine the dependence of the shield requirements on the event spectrum. This paper describes the radiation analysis methods and the results of these analyses for several of the shielding concepts.

Walker, Steven A.↗
NASA NTRS2011

Calculation of Dose Deposition in 3D Voxels by Heavy Ions and Simulation of gamma-H2AX Experiments

The biological response to high-LET radiation is different from low-LET radiation due to several factors, notably difference in energy deposition and formation of radiolytic species. Of particular importance in radiobiology is the formation of double-strand breaks (DSB), which can be detected by -H2AX foci experiments. These experiments has revealed important differences in the spatial distribution of DSB induced by low- and high-LET radiations [1,2]. To simulate -H2AX experiments, models based on amorphous track with radial dose are often combined with random walk chromosome models [3,4]. In this work, a new approach using the Monte-Carlo track structure code RITRACKS [5] and chromosome models have been used to simulate DSB formation. At first, RITRACKS have been used to simulate the irradiation of a cubic volume of 5 m by 1) 450 1H+ ions of 300 MeV (LET 0.3 keV/ m) and 2) by 1 56Fe26+ ion of 1 GeV/amu (LET 150 keV/ m). All energy deposition events are recorded to calculate dose in voxels of 20 m. The dose voxels are distributed randomly and scattered uniformly within the volume irradiated by low-LET radiation. Many differences are found in the spatial distribution of dose voxels for the 56Fe26+ ion. The track structure can be distinguished, and voxels with very high dose are found in the region corresponding to the track "core". These high-dose voxels are not found in the low-LET irradiation simulation and indicate clustered energy deposition, which may be responsible for complex DSB. In the second step, assuming that DSB will be found only in voxels where energy is deposited by the radiation, the intersection points between voxels with dose > 0 and simulated chromosomes were obtained. The spatial distribution of the intersection points is similar to -H2AX foci experiments. These preliminary results suggest that combining stochastic track structure and chromosome models could be a good approach to understand radiation-induced DSB and chromosome aberrations.

Plante, I.↗
NASA NTRS1989

Blockade of 5-hydroxytryptamine(3) receptors prevents cisplatin-induced but not motion- or xylazine-induced emesis in the cat

The effects of the 5-hydroxytryptamine(3) (5-HT-3) antagonists ICS 205-930 and MDL 72222 on the emesis induced by motion or by emetic doses of xylazine (0.66 mg/kg administered SC) or cisplatin (7.5 mg/kg infused over a period of 4-5 min) were investigated in cats. It was found that neither the low (0.1 mg/kg) or the high (1.0 mg.kg) doses of ICS 205-930 or MDL 72222 prevented emesis elicited by screening motion challenges or xylazine. On the other hand, treatment cats by 1.0 mg/kg of ICS 205-930 was effective against cisplatin-induced motion sickness, in agreement with earlier results obtained on other mammals.

Lucot, James B.↗
NASA NTRS1995

Preliminary results of radiation measurements on EURECA

The eleven-month duration of the EURECA mission allows long-term radiation effects to be studied similarly to those of the Long Duration Exposure Facility (LDEF). Basic data can be generated for projections to crew doses and electronic and computer reliability on spacecraft missions. A radiation experiment has been designed for EURECA which uses passive integrating detectors to measure average radiation levels. The components include a Trackoscope, which employs fourteen plastic nuclear track detector (PNTD) stacks to measure the angular dependence of high LET (greater than or equal to 6 keV/micro m) radiation. Also included are TLD's for total absorbed doses, thermal/resonance neutron detectors (TRND's) for low energy neutron fluences and a thick PNTD stack for depth dependence measurements. LET spectra are derived from the PNTD measurements. Preliminary TLD results from seven levels within the detector array show that integrated does inside the flight canister varied from 18.8 +/- 0.6 cGy to 38.9 +/- 1.2 cGy. The TLD's oriented toward the least shielded direction averaged 53% higher in dose than those oriented away from the least shielded direction (minimum shielding toward the least shielded direction varied from 1.13 to 7.9 g/cm(exp 2), Al equivalent). The maximum dose rate on EURECA (1.16 mGy/day) was 37% of the maximum measured on LDEF and dose rates at all depths were less than measured on LDEF. The shielding external to the flight canister covered a greater solid angle about the canister than the LDEF experiments.

Benton, E. V.↗
NASA NTRS2003

Radiation Tests of the Extravehicular Mobility Unit Space Suit for the International Space Station Using Energetic Protons

Measurements using silicon detectors to characterize the radiation transmitted through the EMU space suit and a human phantom have been performed using 155 and 250 MeV proton beams at LLUMC. The beams simulate radiation encountered in space, where trapped protons having kinetic energies on the order of 100 MeV are copious. Protons with 100 MeV kinetic energy and above can penetrate many centimeters of water or other light materials, so that astronauts exposed to such energetic particles will receive doses to their internal organs. This dose can be enhanced or reduced by shielding - either from the space suit or the self-shielding of the body - but minimization of the risk depends on details of the incident particle flux (in particular the energy spectrum) and on the dose responses of the various critical organs. Data were taken to characterize the beams and to calibrate the detectors using the beam in a treatment room at LLUPTF, in preparation for an experiment with the same beams incident on detectors placed in a human phantom within the EMU suit. Nuclear interactions of high-energy protons in various materials produce a small flux of highly ionizing, low-energy secondary radiation. Secondaries are of interest for their biological effects, since they cause doses and especially dose-equivalents to increase relative to the values expected simply from ionization energy loss along the Bragg curve. Because many secondaries have very short ranges, they are best measured in passive track detectors such as CR-39. The silicon detector data presented here are intended to supplement the CR-39 data in regions where silicon has greater sensitivity, in particular the portion of the LET spectrum below 5 keV/micron. The results obtained in this study suggest that optimizing the radiation shielding properties of space suits is a formidable task. The naive assumption that adding mass can reduce risk is not supported by the data, which show that reducing the dose delivered at or near the skin by low-energy particles may increase the dose delivered by energetic particles to points deeper in the body.

Zeitlin, C.↗
NASA NTRSDate not supplied

Plasma Sanitization of Radish Seeds for International Space Station Growth Experiments

Plant growth in space has long been a topic of key interest to enable sustained human presence. Seeds are common sources for microbial growth and must be sanitized before being sent to space. Current disinfection methods use toxic chemicals that require careful handling and dosing or are ineffective against certain seed types. Low temperature plasma provides an alternative to traditional methods. Plasma produces reactive species and ultraviolet light that reduce contaminants on seeds. NASA’s Kennedy Space Center has explored the treatment of radish seeds with plasma for sanitization and germination. Radio Frequency (RF) and Alternating Current (AC) plasma sources provided continuous treatment of radish seeds in a low-pressure and atmospheric environment, respectively. The seeds were analyzed to compare the presence of bacteria, fungi, and the germination rate. Comparisons between direct and indirect treatments, power supplies, treatment times, and treatment pressures showed the importance of proper dosing of reactive species. Higher powers and longer treatment times have shown larger reductions in microbial contaminants. However, extended direct exposure to high powered plasma can sometimes lead to a reduction in germination rates. Overall, plasma has shown promise as a viable alternative to chemical disinfection techniques. *Work supported by NASA's Kennedy Space Center Engineering and Safety Operations Independent Research and Technology Development.

K W Engeling↗
NASA NTRS2000

Analysis of MIR-18 results for physical and biological dosimetry: radiation shielding effectiveness in LEO

We compare models of radiation transport and biological response to physical and biological dosimetry results from astronauts on the Mir space station. Transport models are shown to be in good agreement with physical measurements and indicate that the ratio of equivalent dose from the Galactic Cosmic Rays (GCR) to protons is about 3/2:1 and that this ratio will increase for exposures to internal organs. Two biological response models are used to compare to the Mir biodosimetry for chromosome aberration in lymphocyte cells; a track-structure model and the linear-quadratic model with linear energy transfer (LET) dependent weighting coefficients. These models are fit to in vitro data for aberration formation in human lymphocytes by photons and charged particles. Both models are found to be in reasonable agreement with data for aberrations in lymphocytes of Mir crew members: however there are differences between the use of LET dependent weighting factors and track structure models for assigning radiation quality factors. The major difference in the models is the increased effectiveness predicted by the track model for low charge and energy ions with LET near 10 keV/micrometers. The results of our calculations indicate that aluminum shielding, although providing important mitigation of the effects of trapped radiation, provides no protective effect from the galactic cosmic rays (GCR) in low-earth orbit (LEO) using either equivalent dose or the number of chromosome aberrations as a measure until about 100 g/cm 2 of material is used.

Flight Experiment↗
NASA NTRS2006

Flight Data Update on Long-Term Compound Stability in Dual Sorbent Tubes

Dual Sorbent Tubes (DSTs) are currently the primary method for collecting volatile organic compounds in the cabin air of the International Space Station (ISS). Data from groundbased analysis of these archival air samplers provide a major component of the assessment of ISS air quality by the NASA toxicologist. At the 2005 ICES conference data from the positive control DSTs, returned on Soyuz 7S and 8S, were presented. Positive control tubes are dosed, preflight, with known concentrations of representative contaminant compounds and they are launched to ISS in the DST kit as trip controls. Upon return of the DST kit to the ground, results from analysis of the trip (positive) and laboratory control tubes are used to determine the recoveries: concentration of dosed compounds retained in the tube. Results from positive controls, returned on 7S and 8S showed substantial losses of some compounds dosed into the tubes 156 to 240 days prior to the analysis. Low recoveries are expected for spacecraft air contaminants with similar properties to the poorly recovered dosed compounds. It was shown that compound losses in the control tubes were consistent, which led to the generation of acceptable correction factors for spacecraft air contaminants. Correction factors decrease the accuracy of derived compound concentrations and substantial error could arise under some conditions. An investigation into the mechanism for compound loss is necessary before design modifications can be implemented to improve the DST performance. This paper will update results from the DSTs returned on Soyuz 9S and 10S missions during the latter part of 2005. The data acquired from these returned DSTs will be compared to the 7S and 8S data presented last year. Discussion will focus on the reliability of correction factors and identify any trends in the data. This paper will describe the experimental design and plans to identify the compound loss mechanism.

James, John T.↗
NASA NTRS1999

Relative Efficiency of TLD-100 to High Linear Energy Transfer Radiation: Correction to Astronaut Absorbed Dose

Response of thermoluminescent detectors (TLD-100) to high linear energy transfer (LET) particles has been studied using helium, carbon, silicon, and iron ions from the Heavy Ion Medical Accelerator at Chiba (Japan), iron ions from the Brookhaven National Laboratory (NY) Alternate Gradient Synchrotron, and 53, 134, 185, and 232 MeV protons from the Loma Linda accelerator. Using the measured relative (to 137Cs) dose efficiency, and measured LET spectra from a tissue equivalent proportional counter (TEPC) on 20 Space Shuttle flights, and 7 Mir flights, the underestimation of absorbed dose by these detectors has been evaluated. The dose underestimation is between 15-20% depending upon the flight inclination and shielding location. This has been confirmed by direct correlation of measured dose by TEPC and TLD-100 at a low shielded location in the Shuttle mid-deck. A comparison of efficiency- LET data with a compilation of similar data from TLD-700, shows that shapes of the two curves are nearly identical, but that the TLD-100 curve is systematically lower by about 13%, and is the major cause of dose underestimation. These results strongly suggest that TLDs used for crew dose estimation be regularly calibrated using heavy ions.

Badhwar, G. D.↗
NASA NTRS1999

Relative Efficiency of TLD-100 to Linear Energy Transfer Radiation: Correction to Astronaut Absorbed Dose

Response of thermoluminescent detectors (TLD-100) to high linear energy transfer (LET) particles has been studied using helium, carbon, silicon, and iron ions from the Heavy Ion Medical Accelerator at Chiba (Japan), iron ions from the Brookhaven National Laboratory (NY) Alternate Gradient Synchrotron, and 53, 134, 185, and 232 MeV protons from the Loma Linda accelerator. Using the measured relative (to (137)Cs dose efficiency, and measured LET spectra from a tissue equivalent proportional counter (TEPC) on 20 Space Shuttle flights, and 7 Mir flights, the underestimation of absorbed dose by these detectors has been evaluated. The dose underestimation is between 15-20% depending upon the flight inclination and shielding location. This has been confirmed by direct correlation of measured dose by TEPC and TLD-100 at a low shielded location in the Shuttle mid-deck. A comparison of efficiency- LET data with a compilation of similar data from TLD-700, shows that shapes of the two curves are nearly identical, but that the TLD-100 curve is systematically lower by about 13%, and is the major cause of dose underestimation. These results strongly suggest that TLDs used for crew dose estimation be regularly calibrated using heavy ions.

Badhwar, Gautam D.↗
NASA NTRS1992

Measurements of the radiation dose to LDEF by means of passive dosimetry

A very simple experiment was fielded on LDEF to measure the energetic radiation dose by means of passive dosimetry. It consisted of two identical packets of 16 LiF thermoluminescent dosimeters (TLD) arranged in planar arrays. One array was placed on the leading edge of the spacecraft, the other on the trailing edge. These arrays were installed in opaque packets of 1 mil Al foil and Kapton tape mounted behind an Al plate of 30 mils thickness. The nominal energy thresholds were 14 MeV for protons and 650 keV for electrons. In addition to the flight arrays, two control arrays were prepared which were kept with the flight arrays as long as possible during experimental integration and then stored in the lab. The flight and control arrays were read out alternating in groups of four; it was found that the control dose was negligible. The flight and control detectors were exposed to a 55 MeV proton beam in order to provide a recalibration of the detectors. It was found that the post-flight and pre-flight calibrations were in good agreement. A comparison of results with the prediction shows that the measured dose was a factor of 4 to 5 low. It is possible that there was in-flight annealing of the TLDs as a result of the long mission and perhaps temperature excursions of the sensors. The East-West effect was larger than expected. The ratio of 1.65 is approximately what was expected for the protons alone. Electrons should reduce the dose ratio since electrons add equally to the leading and trailing edge dose. A possible explanation is that the electron dose was negligible compared to the proton dose.

Blake, J. B.↗
NASA NTRS1982

On the validity of equivalent electron fluence for GaAs solar cells

A simple model for particulate radiation damage in shallow-junction heteroface GaAs solar cells is used to evaluate the equivalent electron fluence concept especially in the sense of additivity of electron and proton exposure. It is found that spatial dependent factors for low-energy proton exposure results in a dose dependent equivalent fluence ratio so that additivity within the equivalent fluence concept is generally not possible.

Wilson, J. W.↗
NASA NTRS2000

Trapped Radiation Model Uncertainties: Model-Data and Model-Model Comparisons

The standard AP8 and AE8 models for predicting trapped proton and electron environments have been compared with several sets of flight data to evaluate model uncertainties. Model comparisons are made with flux and dose measurements made on various U.S. low-Earth orbit satellites (APEX, CRRES, DMSP. LDEF, NOAA) and Space Shuttle flights, on Russian satellites (Photon-8, Cosmos-1887, Cosmos-2044), and on the Russian Mir space station. This report gives the details of the model-data comparisons -- summary results in terms of empirical model uncertainty factors that can be applied for spacecraft design applications are given in a companion report. The results of model-model comparisons are also presented from standard AP8 and AE8 model predictions compared with the European Space Agency versions of AP8 and AE8 and with Russian trapped radiation models.

Armstrong, T. W.↗
NASA NTRS2000

Trapped Radiation Model Uncertainties: Model-Data and Model-Model Comparisons

The standard AP8 and AE8 models for predicting trapped proton and electron environments have been compared with several sets of flight data to evaluate model uncertainties. Model comparisons are made with flux and dose measurements made on various U.S. low-Earth orbit satellites (APEX, CRRES, DMSP, LDEF, NOAA) and Space Shuttle flights, on Russian satellites (Photon-8, Cosmos-1887, Cosmos-2044), and on the Russian Mir Space Station. This report gives the details of the model-data comparisons-summary results in terms of empirical model uncertainty factors that can be applied for spacecraft design applications are given in a combination report. The results of model-model comparisons are also presented from standard AP8 and AE8 model predictions compared with the European Space Agency versions of AP8 and AE8 and with Russian-trapped radiation models.

Armstrong, T. W.↗