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NASA NTRS1993

Automation and hypermedia technology applications

This paper represents a progress report on HyLite (Hypermedia Library technology): a research and development activity to produce a versatile system as part of NASA's technology thrusts in automation, information sciences, and communications. HyLite can be used as a system or tool to facilitate the creation and maintenance of large distributed electronic libraries. The contents of such a library may be software components, hardware parts or designs, scientific data sets or databases, configuration management information, etc. Proliferation of computer use has made the diversity and quantity of information too large for any single user to sort, process, and utilize effectively. In response to this information deluge, we have created HyLite to enable the user to process relevant information into a more efficient organization for presentation, retrieval, and readability. To accomplish this end, we have incorporated various AI techniques into the HyLite hypermedia engine to facilitate parameters and properties of the system. The proposed techniques include intelligent searching tools for the libraries, intelligent retrievals, and navigational assistance based on user histories. HyLite itself is based on an earlier project, the Encyclopedia of Software Components (ESC) which used hypermedia to facilitate and encourage software reuse.

Jupin, Joseph H.↗

NASA NTRS1991

Evolution of creep-fatigue life prediction models

The evolution of high-temperature, creep-fatigue, life-prediction methods used for cyclic crack initiation is traced from inception in the late 1940s. The methods reviewed are material models as opposed to structural life prediction models. Material life models are used by both structural durability analysts and by material scientists. The latter use micromechanistic models as guidance to improve a material's crack initiation resistance. Nearly one hundred approaches and their variations have been proposed to date. This proliferation poses a problem in deciding which method is most appropriate for a given application. Approaches have been identified as being combinations of fourteen different classifications. This review is intended to aid both developers and users of high-temperature fatigue life prediction methods by providing a background from which choices can be made.

Halford, Gary R.↗

NASA NTRS1992

Altered immunological response in mice subjected to stress and exposed to fungal spores

Space flight and related factors such as stress appear to have an adverse effect on astronauts' immune systems. The presence of potentially pathogenic microbes including several genera of fungi reported from spacecraft environment may be a cause of concern in such situations. In order to study the role of such organisms in causing opportunistic or allergic diseases in crewmembers, we have tried to develop an animal model. BALB/c mice were suspended upside down for varying periods of time to induce stress, and their lymphocyte functions were evaluated. These studies indicate that the stress resulted in lowered mitogen induced lymphocyte stimulation as represented by 3H-thymidine uptake. We have also studied the ability of these animals to respond to Aspergillus fumigatus spores. The results of the study clearly demonstrate a definite down-regulation in T-cell proliferation and a higher incidence of infection with A. fumigatus.

Kurup, Viswanath P.↗

NASA NTRS1993

Bone culture research

The experiments described are aimed at exploring PTH regulation of production of collagenase and protein inhibitors of collagenase (tissue inhibitors of metalloproteases, TIMP-1 and -2) by osteoblast-like osteosarcoma cells under conditions of weightlessness. The results of this work will contribute to information as to whether a microgravity environment alters the functions and responsiveness of the osteoblast. The objectives of the Bone Culture Research (BCR) experiment are: to observe the effects of microgravity on the morphology, rate of proliferation, and behavior of the osteoblastic cells, UMR 106-01; to determine whether microgravy affects the hormonal sensitivity of osteroblastic cells; and to measure the secretion of collagenase and its inhibitors into the medium under conditions of microgravity. The methods employed will consist of the following: the osteoblast-like cells, UMR-106-01, will be cultured in four NASDA cell culture chambers; two chambers will be subjected to microgravity on SL-J; two chambers will remain on the ground at KSC as ground controls but subjected to an identical set of culture conditions as on the shuttle; media will be changed four times; twice the cells will receive the hormone parathyroid hormone-related protein (PTHrP) and media collected; cells will be photographed under conditions of microgravity; and media and photographs will be analyzed upon return to determine whether functions of the cells changed.

Partridge, Nicola C.↗

NASA NTRS1993

A comparison of queueing, cluster and distributed computing systems

Using workstation clusters for distributed computing has become popular with the proliferation of inexpensive, powerful workstations. Workstation clusters offer both a cost effective alternative to batch processing and an easy entry into parallel computing. However, a number of workstations on a network does not constitute a cluster. Cluster management software is necessary to harness the collective computing power. A variety of cluster management and queuing systems are compared: Distributed Queueing Systems (DQS), Condor, Load Leveler, Load Balancer, Load Sharing Facility (LSF - formerly Utopia), Distributed Job Manager (DJM), Computing in Distributed Networked Environments (CODINE), and NQS/Exec. The systems differ in their design philosophy and implementation. Based on published reports on the different systems and conversations with the system's developers and vendors, a comparison of the systems are made on the integral issues of clustered computing.

Kaplan, Joseph A.↗

NASA NTRS1993

Brief summary of the evolution of high-temperature creep-fatigue life prediction models for crack initiation

The evolution of high-temperature, creep-fatigue, life-prediction methods used for cyclic crack initiation is traced from inception in the late 1940's. The methods reviewed are material models as opposed to structural life prediction models. Material life models are used by both structural durability analysts and by material scientists. The latter use micromechanistic models as guidance to improve a material's crack initiation resistance. Nearly one hundred approaches and their variations have been proposed to date. This proliferation poses a problem in deciding which method is most appropriate for a given application. Approaches were identified as being combinations of thirteen different classifications. This review is intended to aid both developers and users of high-temperature fatigue life prediction methods by providing a background from which choices can be made. The need for high-temperature, fatigue-life prediction methods followed immediately on the heels of the development of large, costly, high-technology industrial and aerospace equipment immediately following the second world war. Major advances were made in the design and manufacture of high-temperature, high-pressure boilers and steam turbines, nuclear reactors, high-temperature forming dies, high-performance poppet valves, aeronautical gas turbine engines, reusable rocket engines, etc. These advances could no longer be accomplished simply by trial and error using the 'build-em and bust-em' approach. Development lead times were too great and costs too prohibitive to retain such an approach. Analytic assessments of anticipated performance, cost, and durability were introduced to cut costs and shorten lead times. The analytic tools were quite primitive at first and out of necessity evolved in parallel with hardware development. After forty years more descriptive, more accurate, and more efficient analytic tools are being developed. These include thermal-structural finite element and boundary element analyses, advanced constitutive stress-strain-temperature-time relations, and creep-fatigue-environmental models for crack initiation and propagation. The high-temperature durability methods that have evolved for calculating high-temperature fatigue crack initiation lives of structural engineering materials are addressed. Only a few of the methods were refined to the point of being directly useable in design. Recently, two of the methods were transcribed into computer software for use with personal computers.

Halford, Gary R.↗

NASA NTRS1994

Low Power Ground-Based Laser Illumination for Electric Propulsion Applications

A preliminary evaluation of low power, ground-based laser powered electric propulsion systems is presented. A review of available and near-term laser, photovoltaic, and adaptive optic systems indicates that approximately 5-kW of ground-based laser power can be delivered at an equivalent one-sun intensity to an orbit of approximately 2000 km. Laser illumination at the proper wavelength can double photovoltaic array conversion efficiencies compared to efficiencies obtained with solar illumination at the same intensity, allowing a reduction in array mass. The reduced array mass allows extra propellant to be carried with no penalty in total spacecraft mass. The extra propellant mass can extend the satellite life in orbit, allowing additional revenue to be generated. A trade study using realistic cost estimates and conservative ground station viewing capability was performed to estimate the number of communication satellites which must be illuminated to make a proliferated system of laser ground stations economically attractive. The required number of satellites is typically below that of proposed communication satellite constellations, indicating that low power ground-based laser beaming may be commercially viable. However, near-term advances in low specific mass solar arrays and high energy density batteries for LEO applications would render the ground-based laser system impracticable.

Lapointe, Michael R.↗

NASA NTRS1993

Generic mission planning concepts for space astronomy missions

The past two decades have seen the rapid development of space astronomy, both manned and unmanned, and the concurrent proliferation of the operational concepts and software that have been produced to support each individual project. Having been involved in four of these missions since the '70's and three yet to fly in the present decade, the authors believe it is time to step back and evaluate this body of experience from a macro-systems point of view to determine the potential for generic mission planning concepts that could be applied to future missions. This paper presents an organized evaluation of astronomy mission planning functions, functional flows, iteration cycles, replanning activities, and the requirements that drive individual concepts to specific solutions. The conclusions drawn from this exercise are then used to propose a generic concept that could support multiple missions.

Guffin, O. T.↗

NASA NTRS1994

Measurement and characterization of force dynamics in high T(sub c) superconductors

Magnetic bearing implementations using more exotic superconducting phenomena have been proliferating in recent years because they have important advantages over conventional implementations. For example, the stable suspension of a six degrees-of-freedom object by superconducting means can be achieved without a control system and with the use of only a single superconductor. It follows that the construction becomes much simpler with decreased need for position sensors and stabilizers. However, it is recognized that the design of superconducting systems can be difficult because important characteristics relating to the 6 degree-of-freedom dynamics of an object suspended magnetically are not readily available and the underlying principles of superconducting phenomena are not yet completely understood. To eliminate some of the guesswork in the design process, this paper proposes a system which can resolve the mechanical properties of suspension by superconductivity and provide position and orientation dependent data about the system's damping, stiffness, and frequency response characteristics. This system employs an actively-controlled magnetically-suspended fine-motion device that can also be used as a six degree-of-freedom force sensor. By attaching the force sensor to a permanent magnet that is being levitated above a superconducting magnet, mechanical characteristics of the superconductor levitation can be extracted. Such information would prove useful for checking the validity of theoretical models and may even give insights into superconducting phenomena.

Higuchi, Toshiro↗

NASA NTRS1994

Semigroup approximation and robust stabilization of distributed parameter systems

Theoretical results that enable rigorous statements of convergence and exponential stability of Galerkin approximations of LQR controls for infinite dimensional, or distributed parameter, systems have proliferated over the past ten years. In addition, extensive progress has been made over the same time period in the derivation of robust control design strategies for finite dimensional systems. However, the study of the convergence of robust finite dimensional controllers to robust controllers for infinite dimensional systems remains an active area of research. We consider a class of soft-constrained differential games evolving in a Hilbert space. Under certain conditions, a saddle point control can be given in feedback form in terms of a solution to a Riccati equation. By considering a related LQR problem, we can show a convergence result for finite dimensional approximations of this differential game. This yields a computational algorithm for the feedback gain that can be derived from similar strategies employed in infinite dimensional LQR control design problems. The approach described in this paper also inherits the additional properties of stability robustness common to game theoretic methods in finite dimensional analysis. These theoretical convergence and stability results are verified in several numerical experiments.

Kurdila, A. J.↗

NASA NTRS1994

Parallelized direct execution simulation of message-passing parallel programs

As massively parallel computers proliferate, there is growing interest in findings ways by which performance of massively parallel codes can be efficiently predicted. This problem arises in diverse contexts such as parallelizing computers, parallel performance monitoring, and parallel algorithm development. In this paper we describe one solution where one directly executes the application code, but uses a discrete-event simulator to model details of the presumed parallel machine such as operating system and communication network behavior. Because this approach is computationally expensive, we are interested in its own parallelization specifically the parallelization of the discrete-event simulator. We describe methods suitable for parallelized direct execution simulation of message-passing parallel programs, and report on the performance of such a system, Large Application Parallel Simulation Environment (LAPSE), we have built on the Intel Paragon. On all codes measured to date, LAPSE predicts performance well typically within 10 percent relative error. Depending on the nature of the application code, we have observed low slowdowns (relative to natively executing code) and high relative speedups using up to 64 processors.

Dickens, Phillip M.↗

NASA NTRS1994

Development of an expert system for power quality advisement using CLIPS 6.0

Proliferation of power electronic devices has brought in its wake both deterioration in and demand for quality power supply from the utilities. The power quality problems become apparent when the user's equipment or systems maloperate or fail. Since power quality concerns arise from a wide variety of sources and the problem fixes are better achieved from the expertise of field engineers, development of an expert system for power quality advisement seems to be a very attractive and cost-effective solution for utility applications. An expert system thus developed gives an understanding of the adverse effects of power quality related problems on the system and could help in finding remedial solutions. The paper reports the design of a power quality advisement expert system being developed using CLIPS 6.0. A brief outline of the power quality concerns is first presented. A description of the knowledge base is next given and details of actual implementation include screen output from the program.

Chandrasekaran, A.↗

NASA NTRS1994

Using expert systems to analyze ATE data

The proliferation of automatic test equipment (ATE) is resulting in the generation of large amounts of component data. Some of this component data is not accurate due to the presence of noise. Analyzing this data requires the use of new techniques. This paper describes the process of developing an expert system to analyze ATE data and provides an example rule in the CLIPS language for analyzing trip thresholds for high gain/high speed comparators.

Harrington, Jim↗

NASA NTRS1994

Comparative Transduction Mechanisms of Vestibular Otolith Hair Cells

Hair cells in the bullfrog vestibular otolith organs regenerate following aminoglycoside ototoxicity. Hair cells in these organs are differentially sensitive to gentamicin, with saccular hair cells and hair cells in the utricular striola being damaged at lower gentamicin concentrations than hair cells in the utricular extrastriola. Regenerating hair cells in these organs have short hair bundles and can be classified into a number of phenotypes using the same morphological criteria used to identify their mature counterparts. Our studies suggest that some supporting cells can convert, or transdifferentiate,into hair cells without an intervening cell division. By stimulating these processes in humans, clinicians may be able to alleviate human deafness and peripheral vestibular disorders by regenerating and replacing lost hair cells. In vivo and in vitro studies were done on cell proliferation and hair cell regeneration.

Baird, Richard A.↗

NASA NTRS1995

Thermal neutral format based on the step technology

The exchange of models is one of the most serious problems currently encountered in the practice of spacecraft thermal analysis. Essentially, the problem originates in the diversity of computing environments that are used across different sites, and the consequent proliferation of native tool formats. Furthermore, increasing pressure to reduce the development's life cycle time has originated a growing interest in the so-called spacecraft concurrent engineering. In this context, the realization of the interdependencies between different disciplines and the proper communication between them become critical issues. The use of a neutral format represents a step forward in addressing these problems. Such a means of communication is adopted by consensus. A neutral format is not directly tied to any specific tool and it is kept under stringent change control. Currently, most of the groups promoting exchange formats are contributing with their experience to STEP, the Standard for Exchange of Product Model Data, which is being developed under the auspices of the International Standards Organization (ISO 10303). This paper presents the different efforts made in Europe to provide the spacecraft thermal analysis community with a Thermal Neutral Format (TNF) based on STEP. Following an introduction with some background information, the paper presents the characteristics of the STEP standard. Later, the first efforts to produce a STEP Spacecraft Thermal Application Protocol are described. Finally, the paper presents the currently harmonized European activities that follow up and extend earlier work on the area.

Almazan, P. Planas↗

NASA NTRS1995

Evaluation of passive microwave precipitation algorithms in wintertime midlatitude situations

The second intercomparison project of the Global Precipitation Climatology Project (GPCP) examined the estimation of midlatitude, cool-season precipitation. As part of that effort, the authors report here on the results of two microwave techniques, the Goddard scattering algorithm and the physical retrieval algorithm of Kummerow. Results from the estimation of instantaneous rain rate for five overpasses of the Special Sensor Microwave/Imager (SSM/I) are presented in a case study mode to illustrate both the strong and weak points of each technique. These five cases represent a sampling of the various types of precipitating systems observed. Results for the complete set of 20 swaths chosen by the United Kingdom Meteorological Office (UKMO) are then categorized by scatterplots and statistics of instantaneous radar versus microwave-estimated rain rate, rain no-rain contingency tables, and scatterplots of areal coverage of rainfall. Neither algorithm produced a good statistical correlation with the radar data, yet in general, both did well at determining rainy areas. Two reasons are suggested for the low correlation coefficients between both algorithms and the radar data. Time differences between the SSM/I overpass and the radar observations can occasionally account for some of the differences. The primary reason for the low correlations, however, appears to be the predominance of very light rain in the area of interest during the winter. Both algorithms are in good spatial agreement with the radar when the radar data are restricted to rates above 1 mm/h. When all radar rain rates are included, the radar areal coverage increases by as much as a factor of 10 in some cases. Because the Kummerow algorithm does not handle such low rain rates over land very well, and because the Goddard scattering algorithm uses 1 mm/h as the minimum reliably detectable rain rate, regimes that contain large areas of very light rain present inherent difficulties for these retrieval methods. Therefore, the proliferation of low rain rates observed during the experiment is the main contributor to low correlation coefficients and high root-mean-square differences. Mididentification of cold surface (e.g., snow cover) as precipitation was also a problem in several instances.

Negri, Andrew J.↗

NASA NTRS1994

Adaptation of rat soleus muscles to 4 wk of intermittent strain

The effect of repeated strains on rat soleus muscles was investigated by stretching active muscles 3 times/wk for 4 wk with two different methods of stretching. The adaptation of myofibers and noncontractile tissue was followed by histochemical techniques and computer-assisted image analysis. Muscle hypertrophy was seen in the slow-stretched muscles, which increased in mass by 13% and increased in myofiber cross-sectional area by 30%. In the fast-stretched muscle, mass increased by 10% but myofiber cross-sectional area actually decreased. This decrease in mean fiber area was the result of a population of very small fibers (population A) that coexisted with slightly smaller normal-sized fibers (population B). Fibers in population A did not have the distribution expected from atrophy compared with atrophic fibers from unloaded muscles; they were much smaller. In addition, there was a 44% increase in noncontractile tissue in the fast-stretched muscles. Thus, soleus muscles subjected to repeated strains respond differently to slow and fast stretching. Slow stretching results in typical muscle hypertrophy, whereas fast stretching produces somewhat larger muscles but with a mixture of small and normal-sized myofibers accompanied by a marked proliferation of noncontractile tissue.

Stauber, W. T.↗

NASA NTRS1994

Induction of carcinoembryonic antigen expression in a three-dimensional culture system

MIP-101 is a poorly differentiated human colon carcinoma cell line established from ascites that produces minimal amounts of carcinoembryonic antigen (CEA), a 180 kDa glycoprotein tumor marker, and nonspecific cross-reacting antigen (NCA), a related protein that has 50 and 90 kDa isoforms, in vitro in monolayer culture. MIP-101 produces CEA when implanted into the peritoneum of nude mice but not when implanted into subcutaneous tissue. We tested whether MIP-101 cells may be induced to express CEA when cultured on microcarrier beads in three-dimensional cultures, either in static cultures as non-adherent aggregates or under dynamic conditions in a NASA-designed low shear stress bioreactor. MIP- 101 cells proliferated well under all three conditions and increased CEA and NCA production 3 - 4 fold when grown in three-dimensional cultures compared to MIP-101 cells growing logarithmically in monolayers. These results suggest that three-dimensional growth in vitro simulates tumor function in vivo and that three-dimensional growth by itself may enhance production of molecules that are associated with the metastatic process.

Jessup, J. M.↗