Engineering topics

Cecchi, Joseph L.

Publications and source records attributed to Cecchi, Joseph L..

3 records

DOE OSTI2022

Enzymatically active high-flux selectively gas-permeable membranes for enhanced oil recovery and carbon capture

A membrane structure for moving a gaseous object species from a first region having an object species first concentration, through the membrane structure, to a second region having an object species second concentration different from the first concentration is described. The membrane includes a supporting substrate having a plurality of pores therethrough, each of the plurality of pores defined by a first end, a second end and a surface of the supporting substrate extending between the first end and the second end as well as a nanoporous layer within the plurality of pores, wherein the nanoporous layer comprises a hydrophilic layer and a hydrophobic layer. The membrane also includes a liquid transport medium within the hydrophilic layer. The liquid transport medium includes a liquideous permeation medium and at least one enzyme within the liquideous permeation medium. The at least one enzyme is reinforced by at least one stabilizing component.

Rempe, Susan Lynne↗

DOE OSTI2018

Ultra-thin enzymatic liquid membrane for CO 2 separation and capture

Here, the limited flux and selectivities of current carbon dioxide membranes and the high costs associated with conventional absorption-based CO 2 sequestration call for alternative CO 2 separation approaches. Here we describe an enzymatically active, ultra-thin, biomimetic membrane enabling CO 2 capture and separation under ambient pressure and temperature conditions. The membrane comprises a ~18-nm-thick close-packed array of 8 nm diameter hydrophilic pores that stabilize water by capillary condensation and precisely accommodate the metalloenzyme carbonic anhydrase (CA). CA catalyzes the rapid interconversion of CO 2 and water into carbonic acid. By minimizing diffusional constraints, stabilizing and concentrating CA within the nanopore array to a concentration 10× greater than achievable in solution, our enzymatic liquid membrane separates CO 2 at room temperature and atmospheric pressure at a rate of 2600 GPU with CO 2 /N 2 and CO 2 /H 2 selectivities as high as 788 and 1500, respectively, the highest combined flux and selectivity yet reported for ambient condition operation.

42 ENGINEERING↗

DOE OSTI2017

Method for atomic layer deposition

An atomic layer deposition method is disclosed for preparing polypeptides. The method comprises providing a solid-phase support comprising a reactive amine monolayer in an atomic layer deposition (ALD) chamber. The solid-phase support is contacted with a first protected amino acid substituted with a protecting group by atomic layer deposition, wherein the protecting group is bonded to a non-side chain amino group of the protected amino acid. A carboxylic acid group of the first protected amino acid is reacted with the reactive amine monolayer, thereby coupling the first protected amino acid to the solid-phase support to produce a coupled-product.

59 BASIC BIOLOGICAL SCIENCES↗