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Benton, E. V.

Publications and source records attributed to Benton, E. V..

At least 127 records · Page 7

The stopping of deuterons in lithium

The interaction of 52 MeV deuterons with lithium was investigated, in view of the optimization of a lithium target for an intense neutron source based on the d-Li stripping reaction. The experimental results are compared with theoretical calculations obtained from an updated version of the Bragg code. This code describes in detail the interaction of charged particles with matter. Within the experimental uncertainties the theoretical results are well reproduced by the experiments.

NASA Program Space Medicine↗

Space Shuttle flight test results of the Cosmic Ray Upset Experiment

CRUX is the first engineering flight experiment designed to test for the incidence of upsets in microcircuits by energetic particles. Harris HM 6504 4K x 1 static CMOS RAM's were used as the test device types in a 1.3 megabit memory which flew on two Shuttle flights. Ground (cyclotron) test information led to a prediction of about one error every 1000 days. No errors were experienced in 10 days of flight. While data were not in conflict with the error prediction and do support it, quantitative validation of the modeling for upsets is not statistically possible. Follow-on hardware (CRUX III) incorporates five different state-of-the-art microcircuits, and is scheduled for flight in October 1984.

Adolphsen, J. W.↗

Radiation measurements aboard Spacelab 1

The radiation environment inside Spacelab 1 was measured by a set of passive radiation detectors distributed throughout the volume inside the module, in the access tunnel, and outside on the pallet. Measurements of the low linear energy transfer (LET) component obtained from the thermoluminescence detectors ranged from 102 to 190 millirads, yielding an average low LET dose rate of 11.2 millirads/day inside the module, about twice the low LET dose rate measured on previous flights of the Space Shuttle. Because of the higher inclination of the orbit (57 versus 28.5 deg for previous Shuttle flights), substantial fluxes of highly ionizing high charge and energy galactic cosmic ray particles were observed, yielding an overall average mission dose-equivalent of about 150 millirems, more than three times higher than that measured on previous Shuttle missions.

Benton, E. V.↗

Linear energy transfer spectrum measurement experiment (P0006)

The linear energy transfer (LET) is the energy deposited per unit path length of charged particle traversing matter. For estimating the rate of damage from single-hit phenomena, the quantity that best combines the radiation environment, orbital situation, and spacecraft shielding is the linear energy transfer (LET) spectrum at the device location. This experiment will measure the LET spectrum behind different shielding configurations for approximately 1 year. The shielding will be increased in increments of approximately 1 G/sq cm up to a maximum shieldng of 16 G/sq cm. In addition to providing critical information to future spacecraft designers, these measurements will also provide data that will be extremely valuable to other experiments on LDEF.

Benton, E. V.↗

Summary of current radiation dosimetry results on manned spacecraft

It is pointed out that the experimental data existing on radiation levels inside orbiting spacecraft are currently limited. However, it is recognized that perhaps the single most important constraint to long-term manned space activity may be related to the complex space radiation environment. For this reason, it is important to know the radiological parameters which determine the biological effects of space radiation on humans. Attention is given to radiation dose measurements, LET (linear energy transfer) spectra for HZE particles, and dosimetry data from U.S. manned spaceflights. In particular, data are now available on dose rates in spacecraft at low altitudes (less than 300 km), while insufficient measurements exist for high altitude and high inclination orbits, geostationary orbits, and many orbits in between. Very little data exist on neutron dose and spectra.

Benton, E. V.↗

Radiation exposures during space flight and their measurement

The paper reviews radiation exposures recorded during space flights of the U.S. and USSR. Most of the data are from manned missions and include discussion of absorbed dose and dose rates as a function of parameters such as altitude, inclination, spacecraft type and shielding. Preliminary data exist on the neutron and HZE-particle component, as well as the LET spectra. For low earth-orbit missions, the dose encountered is strongly altitude-dependent, with a weaker dependence upon inclination. The doses range from about 6 millirad per day for the Space Transportation System No. 3 flight to about 90 mrad per day for Skylab. The effective quality factor (QF) for the near-earth orbits and free space has been estimated to be about 1.5 and about 5.5 respectively. Complete shielding from the galactic cosmic rays does not appear practical because of spacecraft weight limitations.

Benton, E. V.↗

Effects of high-LET particles /A-40/ on the brain of Drosophila melanogaster

To investigate the effects of galactic heavy particles on nervous tissue, Drosophila melanogaster flies were exposed to A-40 from the Super-HILAC accelerator at the Lawrence Berkeley Laboratory. The energy of the particles reaching the Drosophila neurons was 4.8 MeV/nucleon, and the fluence ranged from 60,000 to 80 million particles/sq cm. Thirty-five days after irradiation at the higher fluences, extensive tissue fragmentation and cysts were found. At fluences as low as one hit/two cell bodies (about 5 million) and one hit/90 cell bodies (about 90,000 particles/sq cm or 21 rad average dose) swelling of neuronal cytoplasm and focally fragmented membranes were noted; at fluences ranging from one hit/six to one hit/135 cell bodies, there was frequently a marked increase in glial lamellae around nerve-cell processes, which often had degenerative features. These findings support the view that single hits by heavy particles may injure nervous tissue.

Miquel, J.↗

Ground-based dosimetry support for experiment AR002

Actinomyces levoris colonies were exposed to alpha particles at the 184-inch cyclotron, and Streptomyces levoris colonies were exposed to Ne-20 ions. A description is given of the experimental conditions for each experiment along with tables listing the doses delivered to the colonies. The doses for the Actinomyces levoris exposures came from calibrations made by the cyclotron operators, while the doses for the Streptomyces levoris exposures came in part from cave calibrations and also in part from calculations.

Cassou, R.↗

Project BIOCORE /M212/, a biological cosmic ray experiment - Procedures, summary, and conclusions

The primary objective of the experiment was to determine whether a specific portion of the high Z-high energy (HZE) galactic cosmic ray particle spectrum, especially particles with Z no less than 6, can produce microscopically visible injury of brain and eye tissues. Pocket mice (Perognathus longimembris), obtained from the California desert, were selected as the biological target. Five of these mice were flown on Apollo XVII. Not only the brain and eyes but also many other tissues of these animals were studied for evidence of cosmic ray particle damage. The lack of prior experimental evidence as to the character of the potential injury induced by HZE particles required reliance on the physical characteristics of particle radiation in ascertaining the probable nature of the injury. These characteristics and the key aspects of the experiment are summarized in this paper. Subsequent articles in this special supplement give details of the biological, engineering, and dosimetric aspects of BIOCORE together with the results.

Haymaker, W.↗

Dosimeter design, construction, and implantation

To detect the passage of cosmic ray particles through the heads of the pocket mice during the Apollo XVII flight, a 'monitor' (dosimeter) composed of plastics was prepared and implanted under the scalp. The monitor was mounted on a platform, the undersurface of which fitted the contour of the skull. Numerous tests were run to assure that the presence of the monitor assembly beneath the scalp would be compatible with the well-being of the mice and that the capacity of the monitor to detect the traversal of cosmic ray particles would be preserved over the several weeks during which it would remain under the scalp.

Winter, D. L.↗

Cosmic ray particle dosimetry and trajectory tracing

Five pocket mice (Perognathus longimembris) were flown on Apollo XVII, each with a solid-state (plastic) nuclear track detector implanted beneath its scalp. The subscalp detectors were sensitive to HZE cosmic ray particles with a LET greater than or approximately equal to 0.15 million electron volts per micrometer (MeV/micron). A critical aspect of the dosimetry of the experiment involved tracing individual particle trajectories through each mouse head from particle tracks registered in the individual subscalp detectors, thereby establishing a one-to-one correspondence between a trajectory location in the tissue and the presence or absence of a lesion. The other major aspect was the identification of each registered particle. An average of 16 particles with Z greater than or equal to 6 and 2.2 particles with Z greater than or equal to 20 were found per detector. The track density, 29 tracks/sq cm, when adjusted for detection volume, was in agreement with the photographic emulsion data from an area dosimeter located next to the flight package.

Cruty, M. R.↗

Results of examination of the nasal mucosa

The olfactory epithelium, but not the nasal respiratory epithelium, of the four pocket mice (Perognathus longimembris) that survived their flight on Apollo XVII showed both diffuse alterations and numerous disseminated focal lesions. The olfactory mucosa of the mouse that died during flight was also affected, but to a minor degree insofar as could be determined. All this was in contrast to the normal appearance of the olfactory mucosa of the numerous control animals. A number of possible causes were considered: systemic or regional infection; inhaled particulate material (seed dust); by-products from the KO2 bed in aerosol or particulate form; gas contaminants originating in the flight package; volatile substances from the dead mouse; weightlessness; and cosmic ray particle radiation. Where feasible, studies were conducted in an effort to rule in or rule out some of these potentially causative factors. No definitive conclusions were reached as to the cause of the lesions in the flight mice.

Kraft, L. M.↗

Results of eye examination

Five pocket mice (Perognathus longimembris) were flown on Apollo XVII, and four survived. All the eyes, except one eye from the dead flight mouse, were examined histologically. In the four surviving mice, a total of five cosmic-ray particles which had registered in the subscalp particle detectors had trajectories that intersected the eyes. Four of them (Z = 6.9 for three of the particles and Z greater than or equal to 10 for the fourth) most likely went through the head before reaching the particle detector, while the thindown direction of the fifth (Z greater than or equal to 10) was not determinable. The retinas of the flight animals were found free from histological alterations such as might have been expected from encounters with cosmic-ray particles.

Philpott, D. E.↗

Results of examination of the calvarium, brain, and meninges

Tissue reactions were found around the monitor (dosimeter) assemblies that had been implanted beneath the scalp of the five pocket mice that flew on Apollo XVII. Mitosis in the dentate gyrus of the hippocampal formation was considerably reduced in comparison with that in control animals. Otherwise the brain tissue as well as the meninges in the flight animals appeared unaltered. Since the animals were exposed primarily to high Z-high energy (HZE) cosmic-ray particles at the lower end of the high LET spectrum, the lack of changes in the brain cannot be taken as evidence that the brain will suffer no damage from the heavier HZE particles on prolonged manned missions.

Haymaker, W.↗

Heavy cosmic-ray exposure of Apollo astronauts

A comprehensive study of the heavy-particle cosmic-ray exposure received by the individual astronauts during the nine lunar Apollo missions reveals a significant variation in the exposure as a function of shielding and the phase of the solar cycle. The data are useful in planning for future long-range missions and in estimating the expected biological damage.

Benton, E. V.↗