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NASA NTRS2006

WISE-2005: LBNP/Treadmill and Resistive Exercise Countermeasures Maintain Aerobic Capacity during a 60-d Bed Rest

We have previously documented that supine treadmill exercise within lower body negative pressure (LBNPex) performed 6 sessions (raised dot) wk(sup -1) during 15- and 30-day bed rests (BR) maintained upright aerobic capacity (VO2pk). In the present study, ure are evaluating whether aerobic capacity is maintained during a 60-d BR when the LBNPex frequency is reduced to 2-4 sessions (raised dot) wk(sup -1) and resistance exercise (REX) is added 2-3 sessions (raised dot) wk(sup -1). Eight healthy women (32 plus or minus 4 yrs; 56.4 plus or minus 3.6 kg; 164 plus or minus 8 cm; mean plus or minus SD) performed maximal-exertion, graded treadmill tests before and 3 days after a 60-d, 6 deg. head-down tilt BR. (Earliest day the medical monitors would permit a maximal exercise test post-BR). During BR, four subjects performed no exercise (CON), while four other subjects (EX) performed LBNPex and REX on separate days. The LBNPex countermeasure employed an intermittent (40-80% pre-BR VO2pk), 40-min protocol against an LBNP pressure (-49 plus or minus 3 mmHg) applied to provide a footward force equivalent to 1.0-1.2 body weight. REX consisted of maximal concentric and eccentric supine leg press and heel raise exercises using a gravity-independent flywheel ergometer. Comparisons were performed using paired (within-group) or non-paired (between-group) t-tests. Three days post-BR, VO2pk of the CON group was reduced significantly from pre-BR (Pre:37.2 plus or minus 1.2, Post: 29.4 plus or minus 2 ml (raised dot) kg(sup -1) (raised dot) min(sup -1), P less than 0.05), while the VO2pk of the EX group was not significantly reduced (Pre: 39.6 plus or minus 1.9, Post: 38.0 plus or minus 0.6 ml (raised dot) kg(sup -1) (raised dot) min(sup -1)). Peak heart rate, ventilation, rating of perceived exertion, and respiratory exchange ratio were not significantly different between the two groups pre- and post-BR. These preliminary results suggest that the combined LBNPex and REX countermeasures may be sufficient to maintain upright aerobic capacity after long-duration space flights.

Schneider, Suzanne M.↗

NASA NTRS1980

Fuselage ventilation due to wind flow about a postcrash aircraft

Postcrash aircraft fuselage fire development, dependent on the internal and external fluid dynamics is discussed. The natural ventilation rate, a major factor in the internal flow patterns and fire development is reviewed. The flow about the fuselage as affected by the wind and external fire is studied. An analysis was performend which estimated the rates of ventilation produced by the wind for a limited idealized environmental configuration. The simulation utilizes the empirical pressure coefficient distribution of an infinite circular cylinder near a wall with its boundary later flow to represent the atmospheric boundary layer. The resulting maximum ventilation rate for two door size openings, with varying circumferential location in a common 10 mph wind was an order of magnitude greater than the forced ventilation specified in full scale fire testing. The parameter discussed are: (1) fuselage size and shape, (2) fuselage orientation and proximity to the ground, (3) fuselage-openings size and location, (4) wind speed and direction, and (5) induced flow of the external fire plume is recommended. The fire testing should be conducted to a maximum ventilation rate at least an order of magnitude greater than the inflight air conditioning rates.

Stuart, J. W.↗

NASA NTRS2005

Metronome Use for Coordination of Breaths and Cardiac Compressions Delivered by Minimally-Trained Caregivers During Two-Person CPR

Astronaut crew medical officers (CMO) aboard the International Space Station (ISS) receive 40 hours of medical training over 18 months before each mission, including two-person cardiopulmonary resuscitation (2CPR) as recommended by the American Heart Association (AHA). Recent studies have concluded that the use of metronomic tones improves the coordination of 2CPR by trained clinicians. 2CPR performance data for minimally-trained caregivers has been limited. The goal of this study was to determine whether use of a metronome by minimally-trained caregivers (CMO analogues) would improve 2CPR performance. 20 pairs of minimally-trained caregivers certified in 2CPR via AHA guidelines performed 2CPR for 4 minutes on an instrumented manikin using 3 interventions: 1) Standard 2CPR without a metronome [NONE], 2) Standard 2CPR plus a metronome for coordinating compression rate only [MET], 3) Standard 2CPR plus a metronome for coordinating both the compression rate and ventilation rate [BOTH]. Caregivers were evaluated for their ability to meet the AHA guideline of 32 breaths-240 compressions in 4 minutes. All (100%) caregivers using the BOTH intervention provided the required number of ventilation breaths as compared with the NONE caregivers (10%) and MET caregivers (0%). For compressions, 97.5% of the BOTH caregivers were not successful in meeting the AHA compression guideline; however, an average of 238 compressions of the desired 240 were completed. None of the caregivers were successful in meeting the compression guideline using the NONE and MET interventions. This study demonstrates that use of metronomic tones by minimally-trained caregivers for coordinating both compressions and breaths improves 2CPR performance. Meeting the breath guideline is important to minimize air entering the stomach, thus decreasing the likelihood of gastric aspiration. These results suggest that manifesting a metronome for the ISS may augment the performance of 2CPR on orbit and thus may increase the level of care.

Hurst, Victor, IV↗

NASA NTRS1979

Fuselage ventilation under wind conditions

To determine realistic fuselage ventilation rates for post-crash fires and full-scale fire tests, the effects on wind-about fuselage ventilation rate of various parameters were studied. The parameters investigated were fuselage size and shape, fuselage orientation and proximity to ground, fuselage-opening and location, and wind speed and direction.

Stuart, J. W.↗

NASA NTRS2011

Spacesuit Portable Life Support System Breadboard (PLSS 1.0) Development and Test Results

A multi-year effort has been carried out at NASA-JSC to develop an advanced Extravehicular Activity (EVA) PLSS design intended to further the current state of the art by increasing operational flexibility, reducing consumables, and increasing robustness. Previous efforts have focused on modeling and analyzing the advanced PLSS architecture, as well as developing key enabling technologies. Like the current International Space Station (ISS) Extravehicular Mobility Unit (EMU) PLSS, the advanced PLSS comprises of three subsystems required to sustain the crew during EVA including the Thermal, Ventilation, and Oxygen Subsystems. This multi-year effort has culminated in the construction and operation of PLSS 1.0, a test rig that simulates full functionality of the advanced PLSS design. PLSS 1.0 integrates commercial off the shelf hardware with prototype technology development components, including the primary and secondary oxygen regulators, ventilation loop fan, Rapid Cycle Amine (RCA) swingbed, and Spacesuit Water Membrane Evaporator (SWME). Testing accumulated 239 hours over 45 days, while executing 172 test points. Specific PLSS 1.0 test objectives assessed during this testing include: confirming key individual components perform in a system level test as they have performed during component level testing; identifying unexpected system-level interactions; operating PLSS 1.0 in nominal steady-state EVA modes to baseline subsystem performance with respect to metabolic rate, ventilation loop pressure and flow rate, and environmental conditions; simulating nominal transient EVA operational scenarios; simulating contingency EVA operational scenarios; and further evaluating individual technology development components. Successful testing of the PLSS 1.0 provided a large database of test results that characterize system level and component performance. With the exception of several minor anomalies, the PLSS 1.0 test rig performed as expected; furthermore, many system responses trended in accordance with pre-test predictions.

Vogel, Matt R.↗

NASA NTRS2012

Spacesuit Portable Life Support System Breadboard (PLSS 1.0) Development and Test Results

A multi-year effort has been carried out at the Johnson Space Center to develop an advanced EVA PLSS design intended to further the current state of the art by increasing operational flexibility, reducing consumables, and increasing robustness. This multi-year effort has culminated in the construction and operation of PLSS 1.0, a test rig that simulates full functionality of the advanced PLSS design. PLSS 1.0 integrates commercial off-the-shelf hardware with prototype technology development components, including the primary and secondary oxygen regulators, ventilation loop fan, Rapid Cycle Amine (RCA) swingbed, and Spacesuit Water Membrane Evaporator (SWME). PLSS 1.0 was tested from June 17th through September 30th, 2011. Testing accumulated 233 hours over 45 days, while executing 119 test points. An additional 164 hours of operational time were accrued during the test series, bringing the total operational time for PLSS 1.0 testing to 397 hours. Specific PLSS 1.0 test objectives assessed during this testing include: (1) Confirming prototype components perform in a system level test as they have performed during component level testing, (2) Identifying unexpected system-level interactions (3) Operating PLSS 1.0 in nominal steady-state EVA modes to baseline subsystem performance with respect to metabolic rate, ventilation loop pressure and flow rate, and environmental conditions (4) Simulating nominal transient EVA operational scenarios (5) Simulating contingency EVA operational scenarios (6) Further evaluating prototype technology development components Successful testing of the PLSS 1.0 provided a large database of test results that characterize system level and component performance. With the exception of several minor anomalies, the PLSS 1.0 test rig performed as expected. Documented anomalies and observations include: (1) Ventilation loop fan controller issues at high fan speeds (near 70,000 rpm, whereas the fan speed during nominal operations would be closer to 35,000 rpm) (2) RCA performance at boundary conditions, including carbon dioxide and water vapor saturation events, as well as reduced vacuum quality (3) SWME valve anomalies (4 documented cases where the SWME failed to respond to a control signal or physically jammed, preventing SWME control) (4) Reduction of SWME hollow fiber hydrophobicity and significant reduction of the SWME degassing capability after significant accumulated test time.

Watts, Carly A.↗

NASA NTRS2020

Development of a Photosynthesis Measurement Chamber under Different Airspeeds for Applications in Future Space Crop-Production Facilities

Space crop production systems are being developed to grow fresh produce in-situ to supplement the astronauts’ diet, but the required ventilation rates for crops in different gravity environments remains poorly understood. The reduction or lack of buoyancy-driven convection in reduced gravity environments leads to impaired gas exchange (CO2 absorption, water transpiration and O2 release) at the leaf surface if no extra ventilation is provided, and this could lead to a reduction in biomass production in the long run. To better characterize the influence of different airspeeds on photosynthesis and be able to model this in low gravity, a chamber was designed to interface with a LI-6800 portable photosynthesis system. This paper details the design of this chamber, specifically made to measure whole-plant and small canopy gas exchange at different airspeeds. The fans provide turbulent mixing in the chamber to ensure that it behaves like a continuous stirred tank reactor (CSTR)and that the residence time distribution (RTD) is the same for any fan speed; the computational fluid dynamic (CFD) model of the gas domain (the air in the chamber) hence uses a k-omega turbulence model. An airflow map of the chamber was created using anemometer measurements for the different airspeeds tested, and this was used together with the CFD simulation results to relate the experimentally measured fan outputs to actual airspeeds on top of an artificial plant. Environmental parameters (air temperature, relative humidity, CO2level) are controlled by the LI-6800. This work was funded by NASA Space Biology through the NASA postdoctoral program / USRA.

Lucie Poulet↗

NASA NTRS1994

Using spacecraft trace contaminant control systems to cure sick building syndrome

Many residential and commercial buildings with centralized, recirculating, heating ventilation and air conditioning systems suffer from 'Sick Building Syndrome.' Ventilation rates are reduced to save energy costs, synthetic building materials off-gas contaminants, and unsafe levels of volatile organic compounds (VOC's) accumulate. These unsafe levels of contaminants can cause irritation of eyes and throat, fatigue and dizziness to building occupants. Increased ventilation, the primary method of treating Sick Building Syndrome is expensive (due to increased energy costs) and recently, the effectiveness of increased ventilation has been questioned. On spacecraft venting is not allowed, so the primary methods of air quality control are; source control, active filtering, and destruction of VOC's. Four non-venting contaminant removal technologies; strict material selection to provide source control, ambient temperature catalytic oxidation, photocatalytic oxidation, and uptake by higher plants, may have potential application for indoor air quality control.

Graf, John C.↗

NASA NTRS1976

Control of thermal balance by a liquid circulating garment based on a mathematical representation of the human thermoregulatory system

Test data and a mathematical model of the human thermoregulatory system were used to investigate control of thermal balance by means of a liquid circulating garment (LCG). The test data were derived from five series of experiments in which environmental and metabolic conditions were varied parametrically as a function of several independent variables, including LCG flowrate, LCG inlet temperature, net environmental heat exchange, surrounding gas ventilation rate, ambient pressure, metabolic rate, and subjective/obligatory cooling control. The resultant data were used to relate skin temperature to LCG water temperature and flowrate, to assess a thermal comfort band, to demonstrate the relationship between metabolic rate and LCG heat dissipation, and so forth. The usefulness of the mathematical model as a tool for data interpretation and for generation of trends and relationships among the various physiological parameters was also investigated and verified.

Kuznetz, L. H.↗

NASA NTRS1977

Metabolic and cardiovascular adaptation, monkey. NASA SMD 3, project 76, experiment 44 conducted at NASA/JSC, 14-25 May 1977

The biomedical results from an experiment on a monkey subjected to space flight conditions are reported. A background history of the development and testing of an experiment system designed to permit measurement of physiological parameters in subhuman primates during continuous, comfortable, couch restraint for periods of up to 30 days is reviewed. Of major importance in the experimental design of the system was the use of a fiberglass pod, which could be sealed and subdivided into upper and lower parts, to monitor and control the physiological responses for various parts of the animal's body. The experiment was conducted within the Spacelab Simulator for a period of 11 days. Data recorded includes: Spacelab Simulator cabin temperature; ventilation rate; pod internal temperature; fraction percent oxygen; fraction percent carbon dioxide; oxygen consumption rate; carbon dioxide production rate; respiratory quotient; intrathoracic temperature; heart rate; mean aortic pressure; mean ventricular pressure; diurnal variation of parameters measured; comparison of mean preflight, flight, and postflight values of the parameters measured; and correlation matrix for the parameters measured.

Pace, N.↗

NASA NTRS1974

Evaluation of exercise-respiratory system modifications and preliminary respiratory-circulatory system integration scheme

The respiratory control system, functioning as an independent system, is presented with modifications of the exercise subroutine. These modifications illustrate an improved control of ventilation rates and arterial and compartmental gas tensions. A very elementary approach to describing the interactions of the respiratory and circulatory system is presented.

Gallagher, R. R.↗

NASA NTRS1974

Evaluation of exercise-respiratory system modifications and integration schemes for physiological systems

Exercise subroutine modifications are implemented in an exercise-respiratory system model yielding improvement of system response to exercise forcings. A more physiologically desirable respiratory ventilation rate in addition to an improved regulation of arterial gas tensions and cerebral blood flow is observed. A respiratory frequency expression is proposed which would be appropriate as an interfacing element of the respiratory-pulsatile cardiovascular system. Presentation of a circulatory-respiratory system integration scheme along with its computer program listing is given. The integrated system responds to exercise stimulation for both nonstressed and stressed physiological states. Other integration possibilities are discussed with respect to the respiratory, pulsatile cardiovascular, thermoregulatory, and the long-term circulatory systems.

Gallagher, R. R.↗

NASA NTRS1980

Reduced bleed air extraction for DC-10 cabin air conditioning

It is noted that a significant fuel savings can be achieved by reducing bleed air used for cabin air conditioning. Air in the cabin can be recirculated to maintain comfortable ventilation rates but the quality of the air tends to decrease due to entrainment of smoke and odors. Attention is given to a development system designed and fabricated under the NASA Engine Component Improvement Program to define the recirculation limit for the DC-10. It is shown that with the system, a wide range of bleed air reductions and recirculation rates is possible. A goal of 0.8% fuel savings has been achieved which results from a 50% reduction in bleed extraction from the engine.

Newman, W. H.↗

NASA NTRS1986

Space bio-technology in housing

Gas chromatography and mass spectrometry data obtained from monitoring atmospheric pollutants in Skylab spurred studies of indoor pollutants in terrestrial buildings. Subsequent studies of techniques for removing the pollutants from space habitats have led to building concepts which achieve the same purpose on earth. The Skylab data indicated that the synthesized organic materials used in many modern buildings, furnishings, personal clothing and aerosols add significant amounts of chemicals to the indoor atmosphere. Lowered circulation and ventilation rates to conserve energy have caused trapping of these substances in buildings. Studies of methods for space modules which will use plants and microbes to absorb airborne and wastewater pollutants have defined biotechnology designs which can be applied to remove pollutants from air and wastewater organically. Plant roots trap pollutants from wastewater and leaves readily absorb air pollutants, as well as improve the overall energy efficiency of buildings. Several designs which incorporate biotechnology to enhance both the aesthetics and efficiency of homes and office buildings are illustrated.

Wolverton, B. C.↗

NASA NTRS1998

Human Physiological Responses to Cycle Ergometer Leg Exercise During +Gz Acceleration

Spaceflight and bed-rest deconditioning decrease maximal oxygen uptake (aerobic power), strength, endurance capacity, and orthostatic tolerance. In addition to extensive use of muscular exercise conditioning as a countermeasure for the reduction in aerobic power (VO(sub 2max)), stimuli from some form of +Gz acceleration conditioning may be necessary to attenuate the orthostatic intolerance component of this deconditioning. Hypothesis: There will be no significant difference in the physiological responses (oxygen uptake, heart rate, ventilation, or respiratory exchange ratio) during supine exercise with moderate +Gz acceleration.

Chou, J. L.↗

NASA NTRS2018

Relationships Between the Planetary Boundary Layer Height and Surface Pollutants Derived from Lidar Observations over China: Regional Pattern and Influencing Factors

The frequent occurrence of severe air pollution episodes in China has been a great concern and thus the focus of intensive studies. Planetary boundary layer height (PBLH) is a key factor in the vertical mixing and dilution of near-surface pollutants. However, the relationship between PBLH and surface pollutants, especially particulate matter (PM) concentration across China, is not yet well understood. We investigate this issue at 1600 surface stations using PBLH derived from space-borne and ground-based lidar, and discuss the influence of topography and meteorological variables on the PBLH–PM relationship. Albeit the PBLH–PM correlations are roughly negative for most cases, their magnitude, significance, and even sign vary considerably with location, season, and meteorological conditions. Weak or even uncorrelated PBLH–PM relationships are found over clean regions (e.g., Pearl River Delta), whereas nonlinearly negative responses of PM to PBLH evolution are found over polluted regions (e.g., North China Plain). Relatively strong PBLH–PM interactions are found when the PBLH is shallow and PM concentration is high, which typically corresponds to wintertime cases. Correlations are much weaker over the highlands than the plains regions, which may be associated with lighter pollution loading at higher elevations and contributions from mountain breezes. The influence of horizontal transport on surface PM is considered as well, manifested as a negative correlation between surface PM and wind speed over the whole nation. Strong wind with clean upwind air plays a dominant role in removing pollutants, and leads to obscure PBLH–PM relationships. A ventilation rate is used to jointly consider horizontal and vertical dispersion, which has the largest impact on surface pollutant accumulation over the North China Plain. As such, this study contributes to improved understanding of aerosol–planetary boundary layer (PBL) interactions and thus our ability to forecast surface air pollution.

Su, Tianning↗

NASA NTRS2023

Ventilation Heat Exchanger / Flow Meter for xPLSS

The flow meter / heat exchanger (FMHX) in the ventilation loop of the exploration EMU cools the ventilation gas and measures the ventilation flow rate. The heat exchanger transfers heat from the ventilation gas to the thermal control loop via a miniature shell-and-tube heat exchanger. The flow meters calculate the flow rate of gas through the ventilation loop based on the pressure drop across the heat exchanger core. Creare has delivered four design validation test (DVT) heat exchangers and five DVT flow meters to NASA JSC to support development of the exploration portable life support system (xPLSS). This paper describes the design and performance of the DVT units.The heat exchangers are designed to cool the ventilation gas to a specified temperature with low pressure losses under the most challenging operating conditions. The measured performance of the DVT heat exchangers agrees well with design models and meets all performance requirements. The flow meters use a MEMS thermal flow sensor to produce a signal that is proportional to a small bypass flow around the heat exchanger core. They are designed to achieve high measurement accuracy across the full range of xPLSS operating conditions. We calibrated the flow meters in a special-purpose flow facility that simulates operation in the xPLSS ventilation loop. Calibration testing shows that DVT flow meters produce digital output for vent loop mass flow that meets NASA’s accuracy requirements across the range of xPLSS operating conditions. This paper reviews the design of the heat exchangers and flow meters and presents data from the final flow meter calibration testing, heat exchanger performance validation, and initial ground testing in NASA’s xPLSS.

spacesuit↗

NASA NTRS2023

Ventilation Heat Exchanger / Flow Meter for xPLSS

spacesuit↗