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The Zero Boil-Off Tank Experiment Ground Testing and Verification of Fluid and Thermal Performance

The Zero Boil-Off Technology (ZBOT) Experiment involves performing a small scale International Space Station (ISS) experiment to study tank pressurization and pressure control in microgravity. The ZBOT experiment consists of a vacuum jacketed test tank filled with an inert fluorocarbon simulant liquid. Heaters and thermo-electric coolers are used in conjunction with an axial jet mixer flow loop to study a range of thermal conditions within the tank. The objective is to provide a high quality database of low gravity fluid motions and thermal transients which will be used to validate Computational Fluid Dynamic (CFD) modeling. This CFD can then be used in turn to predict behavior in larger systems with cryogens. This paper will discuss the work that has been done to demonstrate that the ZBOT experiment is capable of performing the functions required to produce a meaningful and accurate results, prior to its launch to the International Space Station. Main systems discussed are expected to include the thermal control system, the optical imaging system, and the tank filling system.This work is sponsored by NASAs Human Exploration Mission Directorates Physical Sciences Research program.

Fluid management↗

GeneLab

GeneLab collects and enables analysis of spaceflight and ground-based spaceflight simulation genomic data, RNA and protein expression, and metabolic profiles. It interfaces with other existing databases containing spaceflight omic data. The 2011 National Research Council (NRC) Decadal Survey on NASA Life and Physical Sciences called for increased opportunities for multi-investigator spaceflight opportunities and greater use of genomic approaches to meet the needs of NASA researchers. To address these recommendations of the NRC Decadal Survey, the Space Life and Physical Sciences Research and Applications Division of NASA's Human Exploration and Operations Mission Directorate has initiated a transition to an Open Science architecture to increase research opportunities, and has developed the GeneLab Platform based on highly leveraged and integrated bioinformatics analytics. GeneLab is an interactive, open-access resource where scientists can upload, download, store, search, share, transfer, and analyze omics data from spaceflight and corresponding analogue experiments. Users can explore GeneLab datasets in the Data Repository, analyze data using the Analysis Platform, visualize high-order data and create collaborative projects using the Collaborative Workspace. Our primary goal is to maximize the utilization of the valuable biological research conducted aboard the International Space Station (ISS) by collecting genomic, transcriptomic, proteomic, and metabolomics data known as “omics”. By providing a portal linking processed data to flight parameters, GeneLab enables exploration of the molecular network responses of terrestrial biology to the space environment. This allows researchers to understand the complex responses of biological systems to the space environment. This technology development activity was transferred from the Human Exploration and Operations Mission Directorate to the Science Mission Directorate Division of Biological and Physical Sciences (BPS) in October 2020.

GeneLab↗

What's New in the PSI? (Physical Sciences Informatics)

The NASA Physical Sciences Informatics (PSI) database is NASA’s archival for physical sciences research in microgravity – on ISS and also other reduced gravity platforms. The database has been making data from microgravity physical science investigations publicly available since its launch late 2014. The database was an early investment in Open Science for NASA’s Biophysics and Physical Sciences (BPS) Division of the Science Mission Directorate (SMD), who conducts fundamental and applied physical sciences yielding research data in 6 disciplines: biophysics, combustion science, complex fluids, fluid physics, fundamental physics, and materials science. PSI started initially with data from 14 microgravity investigations. Receipt of data through the years and an annual NRA to fund ground investigations extending flight datasets has increased the total to 72 investigations available with 8 new datasets in the 2020 NRA (NNH20ZDA014N). These new datasets are open for public access at the PSI website at https://www.nasa.gov/PSI.

Physical Sciences Informatics PSI database↗

SMD Technology Highlights

Three technology highlights from the Science Mission Directorate (SMD) Astrophysics Division, Biological and Physical Sciences Division, and Planetary Science Division are featured: a) A new class of X-ray detector with unprecedented energy resolution and array size could help transform our understanding of the cosmos through unparalleled vision into the otherwise invisible universe. b) An autonomous microfluidic culturing system with CubeSat heritage is teaming up with two state-of-the-art radiation detectors to measure how biology responds to the radiation and reduced gravity environment on the lunar surface. c) Several core technologies developed via the Hot Operating Temperature Technology (HOTTech) Program were recently tested in the Glenn Extreme Environment Rig (GEER), which simulates the conditions on the surface of Venus.

yeast↗

Laboratory For Atmospheres 1996 Annual Report

A broad and vigorous science program in NASA is vital for the advancement of knowledge through space research.Scientists at NASA in collaboration with outside scientists play a key role in conceiving new space missions, providing mission requirements, and carrying out research oriented towards explaining the behavior of Earth's and other planetary systems. NASA scientists also supply outside scientists with technical assistance and scientific data.The Laboratory for Atmospheres serves as the focal point of a broad theoretical and experimental research program. The goal of the program is to study all aspects of the atmospheres of the Earth and other planets, including their structural, dynamical, radiative, and chemical properties. The Laboratory is one of four science laboratories of the at the Goddard Space Flight Center (GSFC). The Laboratory is located in Greenbelt, MD along with the and the. , located in New York, NY, is the fourth science Laboratory in the Directorate. The Directorate also includes the Global Change Data Center and the Space Data and Computing Division (SDCD). The GSFC is the lead center for science and management of the, which is one of the four NASA enterprises. Earth Sciences Directorate Laboratory for Terrestrial Physics Laboratory for Hydrospheric Processes The Goddard Institute for Space Studies (GISS) Mission to Planet Earth (MTPE)This report is a general statement of the purpose and philosophy of the Laboratory and of its role within NASA. It also includes a broad description of the research areas; information on human resources, scientific interactions, and outreach activities with the outside community; and a selection of the major accomplishments achieved in the Laboratory in calendar year 1996.

Steven E. Platnick↗

Benchmark Models for Classification of Radiation Type Induced in Immune Cells

NASA Biological and Physical Sciences and the Science Mission Directorate have published a benchmark dataset of mouse immune cells subjected to radiation-induced DNA damage. The dataset comprises ML-ready microscopic imagery of said cells, including labels indicating radiation type and dose. The machine learning team at NASA Interagency Implementation and Advanced Concept Team (IMPACT) created multiple benchmark models. Initially, we conducted a preliminary analysis using thresholding. The algorithm used thresholds on average brightness of the available images to classify them into their respective radiation type. We also tested machine learning approaches. Convolutional Neural Networks (CNN) emerged as the best-performing model. This poster presents the benchmark scores obtained by the models.

Vishal Perekadan↗

SMD Technology Highlights

Six technology highlights from the Science Mission Directorate (SMD) Heliophysics, Astrophysics, Earth, and Biological and Physical Sciences divisions. Technologies featured include 1. the 1653 m2 Solar Cruiser Solar Sail Propulsion system to enable missions to reach novel and otherwise difficult or impossible destinations for observing the Sun. 2. Technology sponsored by NASA and developed by MIT Space Nanotechnology Lab is developing high-performance space instrumentation for more powerful future X-ray telescopes that will study the dynamics of the high-energy universe. 3. Active thermal control technology that will help enable large ultra-stable telescopes needed to detect and characterize Earth-like planets around other stars. 4. SMD sponsored high-performance infrared sensors with reduced requirements for cooling onboard satellites and these sensors could potentially be flown on small satellite platforms like CubeSats. 5. A new technology that will utilize electron beams/ultraviolet light to remove dust that could help protect future space assets and astronauts from dangerous effects that arise from Moon/Mars dust exposure. 6. Studies using model organisms on ISS to understand the impact of the spaceflight environment on organisms in preparation for long-duration missions.

solar sail↗

NASA Ames Institutional Scientific Collection (ISC)

NASA's current human space flight research is directed towards enabling human space exploration beyond Low Earth Orbit (LEO). The Space Flight Payload Projects; Rodent Research, Cell Science, and Microbial Labs, flown on the International Space Station (ISS), benefit both the global life sciences and commercial space communities. Verified data sets, science results, peer-reviewed publications, and returned biospecimens, collected and analyzed for flight and ground investigations, are all part of the knowledge base within NASA’s Human Exploration and Operations Mission Directorate’s Space Life and Physical Sciences Research and Applications (SLPSRA) Division, specifically the Human Research and Space Biology Programs. These data and biospecimens are made available through the public LSDA website. The Ames Institutional Scientific Collection (ISC), or ARC Biobank, stores flight and ground biospecimens from Space Shuttle and ISS programs. These specimens are curated and managed by the Ames Life Sciences Data Archive (ALSDA), an internal node of NASA's Life Sciences Data Archive (LSDA). The ARC Biolbank stores over 15,000 specimens from experiments dating from 1984 to present. Currently available specimens include tissues from the circulatory, digestive, endocrine, excretory, integumentary, muscular, neurosensory, reproductive, respiratory and skeletal systems. The most recent contributions include RNA, DNA and protein extracts from Rodent Research 1 and tissues from Rodent Research 4. NASA's biospecimen collection represents a unique and limited resource. The use of these biospecimens maximizes utilization and scientific return from these unique spaceflight payload and ground control research subjects. These biospecimens are harvested following complex, costly NASA research activities to meet primary scientific objectives. Once the primary scientific objectives have been met, the remaining specimens are made available to provide secondary opportunities for complementary studies or new investigations to broaden research without large expenditures of time or resources. Innovative ways of sharing this information ultimately advances the frontiers of human space exploration as well as scientific understanding of the effects of gravity on life on earth.

French, Alison J.↗

Accelerating Space Life Sciences: Successes and Challenges of Biospecimen and Data Sharing

NASA's current human space flight research is directed towards enabling human space exploration beyond Low Earth Orbit (LEO). To that end, NASA Space Flight Payload Projects; Rodent Research, Cell Science, and Microbial Labs, flown on the International Space Station (ISS), benefit the global life sciences and commercial space communities. Verified data sets, science results, peer-reviewed publications, and returned biospecimens, collected and analyzed for flight and ground investigations, are all part of the knowledge base collected by NASA's Human Exploration and Operations Mission Directorate's Space Life and Physical Sciences Research and Applications (SLPSRA) Division, specifically the Human Research and Space Biology Programs. These data and biospecimens are made available through the public Life Sciences Data Archive (LSDA) website to promote basic discovery, pre-clinical and clinical science.The NASA Institutional Scientific Collection (ISC), stores flight and ground biospecimens from Space Shuttle and ISS programs. These specimens are curated and managed by the Ames Life Sciences Data Archive (ALSDA), an internal node of NASA's LSDA. The ISC stores over 30,000 specimens from experiments dating from 1984 to present. Currently available specimens include tissues from the circulatory, digestive, endocrine, excretory, integumentary, muscular, neurosensory, reproductive, respiratory and skeletal systems.NASA's biospecimen collection represents a unique and limited resource of unique spaceflight payload and ground control research subjects. These specimens are harvested according to well established SOPs that maintain their quality and integrity. Once the primary scientific objectives have been met, the remaining specimens are made available to provide secondary opportunities for complementary studies or new investigations to broaden research without large expenditures of time or resources. Website: https://lsda.jsc.nasa.gov/

Scott, Ryan T.↗

Research program of the Geodynamics Branch

This report is the Fourth Annual Summary of the Research Program of the Geodynamics Branch. The branch is located within the Laboratory for Terrestrial Physics of the Space and Earth Sciences Directorate of the Goddard Space Flight Center. The research activities of the branch staff cover a broad spectrum of geoscience disciplines including: tectonophysics, space geodesy, geopotential field modeling, and dynamic oceanography. The NASA programs which are supported by the work described in this document include the Geodynamics and Ocean Programs, the Crustal Dynamics Project and the proposed Ocean Topography Experiment (TOPEX). The reports highlight the investigations conducted by the Geodynamics Branch staff during calendar year 1985. The individual papers are grouped into chapters on Crustal Movements and Solid Earth Dynamics, Gravity Field Modeling and Sensing Techniques, and Sea Surface Topography. Further information on the activities of the branch or the particular research efforts described herein can be obtained through the branch office or from individual staff members.

Kahn, W. D.↗

SMD Technology Highlights

Two technology highlights from the Science Mission Directorate (SMD) Planetary Science Division and Biological and Physical Sciences division are featured: a) The Dynamic Radioisotope Power Systems Project (DRPS) may enable lunar science payloads to survive and thrive during the harsh lunar night. New robust DRPS have been built and delivered by industry and are in the process of being tested at NASA’s Glenn Research Center. b) NASA's Plant Water Management (PWM) project is demonstrating that even without the help of gravity, hydroponic plant watering methods can enable plant habitats aboard crewed or robotic space missions. On Earth, plants draw water upwards through the roots against gravity, via capillary action, which orients the plant and enables display of its canopy (foliage and branches) for optimal photosynthesis and transpiration. The plant grows above the nutrient-rich soil as the water U.S. Astronaut Kate Rubins poses with PWM after nearly doubling the science returns of the ISS experiment by drawing on her wealth of wet lab operations and handling experience—on Earth and in space.

RPS↗

NASA BPS Reduced Gravity Integrated Computational Materials Engineering (ICME) Study

The Biological and Physical Sciences (BPS) Division of NASA’s Science Mission Directorate (SMD), and its predecessors, has sponsored extensive flight and ground experiments yielding benchmark datasets in many materials science research areas including thermophysical properties and solidification microstructure formation and evolution. The subject study sought to motivate and focus BPS’s engagement within the broader Integrated ICME community to understand the phenomena underlying material processing, structure, and properties in the microgravity environment of space and to support future space exploration efforts.

Louise Littles↗

The “Gravity” of Combustion, Fluid and Soft Matter Research

Over the next year, the National Academies of Science, Engineering and Medicine (NASEM) will be developing the report for the next Decadal Survey on Life and Physical Sciences Research in space 2023-2032. This document will be used by the Science Mission Directorate in the National Aeronautics and Space Administration (NASA) to provide the framework for the vision, priorities, and strategic plan and budget for NASA’s research efforts in the area of biological and physical sciences in space, especially with regards to effects of gravity or the lack thereof. Gravity can affect fluid motion, shapes interfacial boundaries, squeezes compressible volumes by their surroundings, and ultimately affects heat and mass transfer as well as chemical reactions. NASEM will be requesting input from the research community via white papers in order to generate a comprehensive vision and strategy for a decade of transformative science at the frontiers of science space. Note: Accompanying videos are included in this submission and are listed based on there corresponding slide. For viewing you will need to download each mp4 formatted video, total run time 4 mins 2 secs. w/ color/sound.

combustion↗

SMD Technology Highlights

Seven technology highlights from the Science Mission Directorate (SMD) Astrophysics, Planetary Science, Heliophysics, and Biological and Physical Sciences, and Earth Science divisions are featured: 1. Technology using precisely controlled ultraviolet light source that to suppress electrostatic noise in gravitational wave observatories 2. New micro-shutter technology that will enable space telescopes to perform spectroscopy on a large number of objects simultaneously 3. An optical seismometer that is micro-fabricated, easy to manufacture, immune to radiation damage, and operates with low power consumption to characterize ice sheets and mantle on icy worlds 4. Rediscovering the lost art of fluxgate magnetometer cores 5. Innovative technology to measure muscle strength of worms in space to prepare astronauts for future missions 6. A new state-of-the-art sensor and satellite platform to enable continued monitoring of Earth’s radiant energy system 7. Novel Algorithms to merge ground- and space-based data to forecast air pollution events

ultraviolet↗

NASA Access 2 Space Workshop: Summary Report: Increased Science Return through Rideshare

This report summarizes the Access to Space (A2S) Workshop held on February 25-27, 2020 at the Johns Hopkins University Applied Physics Laboratory (APL) and hosted by NASA’s Science Mission Directorate (SMD). This workshop solicited community input on the creation and management of an ESPA-class1payload pipeline for NASA SMD launches. The workshop brought together roughly 180 participants including scientists, engineers, instrument developers, launch providers, and policy makers across NASA centers, government agencies, commercial industry, research institutes, and academia.

ESPA-Class Spacecraft↗

An Overview of SBIR Phase 2 Physical Sciences and Biomedical Technologies in Space

Technological innovation is the overall focus of NASA's Small Business Innovation Research (SBIR) program. The program invests in the development of innovative concepts and technologies to help NASA's mission directorates address critical research and development needs for agency projects. This report highlights innovative SBIR Phase II projects from 2007-2012 specifically addressing areas in physical sciences and biomedical technologies in space, which is one of six core competencies at NASA Glenn Research Center. There are twenty two technologies featured with emphasis on a wide spectrum of applications such as reusable handheld electrolyte, sensor for bone markers, wideband single crystal transducer, mini treadmill for musculoskeletal, and much more. Each article in this report describes an innovation, technical objective, and highlights NASA commercial and industrial applications. This report serves as an opportunity for NASA personnel including engineers, researchers, and program managers to learn of NASA SBIR's capabilities that might be crosscutting into this technology area. As the result, it would cause collaborations and partnerships between the small companies and NASA Programs and Projects resulting in benefit to both SBIR companies and NASA.

electrolytes↗

Space Settlements: A Design Study

Nineteen professors of engineering, physical science, social science, and architecture, three volunteers, six students, a technical director, and two co-directors worked for ten weeks to construct a convincing picture of how people might permanently sustain life in space on a large scale, and to design a system for the colonization of space. Because the idea of colonizing space has awakened strong public interest, the document presented is written to be understood by the educated public and specialists in other fields. It also includes considerable background material. A table of units and conversion factors is included to aid the reader in interpreting the units of the metric system used in the report.

Richard D Johnson↗

The NASA Space Life Sciences Training Program: Accomplishments Since 2013

The NASA Space Life Sciences Training Program (SLSTP) provides undergraduate students entering their junior or senior years with professional experience in space life science disciplines. This challenging ten-week summer program is held at NASA Ames Research Center. The primary goal of the program is to train the next generation of scientists and engineers, enabling NASA to meet future research and development challenges in the space life sciences. Students work closely with NASA scientists and engineers on cutting-edge research and technology development. In addition to conducting hands-on research and presenting their findings, SLSTP students attend technical lectures given by experts on a wide range of topics, tour NASA research facilities, participate in leadership and team building exercises, and complete a group project. For this presentation, we will highlight program processes, accomplishments, goals, and feedback from alumni and mentors since 2013. To date, 49 students from 41 different academic institutions, 9 staffers, and 21 mentors have participated in the program. The SLSTP is funded by Space Biology, which is part of the Space Life and Physical Sciences Research and Application division of NASA's Human Exploration and Operations Mission Directorate. The SLSTP is managed by the Space Biology Project within the Science Directorate at Ames Research Center.

education↗