Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “mason”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 records
All sourcesNASA NTRSDOE OSTI
NASA NTRS1988

Supernova 1987A in the Large Magellanic Cloud; Proceedings of the Fourth George Mason Astrophysics Workshop, George Mason University, Fairfax, VA, Oct. 12-14, 1987

Papers concerning SN 1987A are presented, covering topics such as images and spectrograms of the SN 1987A progenitor, a linear polarimetric study of SN 1987A, the energetics, nature, and uniqueness of the supernova, comparison of the SN 1987A light curve with other type II supernovae, P-Cygni features and photospheric velocities, the neutrino burst from SN 1987A, mass determination of neutrinos, neutrino transport, energetics, and oscillations. Additional papers discuss supernovae light echoes, the UV interstellar spectrum of SN 1987A, theoretical models of SN 1987A, circumstellar and interstellar interaction, the supernova as a stripped asymptotic-branch giant in a binary system, pulsar formation and the fall back mass fraction, the signals of particle acceleration at SN 1987A, the effects of the mixing of the ejecta on the hard X-ray emissions from the supernova, possible s-process gamma-ray lines in supernovae, detectability of early thermal radiation from a neutron star in SN 1987A, NASA studies of the supernova, and information exchange for SN 1987A. Observational studies presented include optical, IR, radio, and UV observations, IR speckle-interferometry, coded mask X-ray observations, broad band X-ray imaging spectrophotometry, gamma-ray and thermal X-ray observations, and reports from several observatories.

Kafatos, Minas↗
DOE OSTI2023

Drug discovery efforts at George Mason University

With over 39,000 students, and research expenditures in excess of $200 million, George Mason University (GMU) is the largest R1 (Carnegie Classification of very high research activity) university in Virginia. Mason scientists have been involved in the discovery and development of novel diagnostics and therapeutics in areas as diverse as infectious diseases and cancer. Below are highlights of the efforts being led by Mason researchers in the drug discovery arena. To enable targeted cellular delivery, and non-biomedical applications, Veneziano and colleagues have developed a synthesis strategy that enables the design of self-assembling DNA nanoparticles (DNA origami) with prescribed shape and size in the 10 to 100 nm range. The nanoparticles can be loaded with molecules of interest such as drugs, proteins and peptides, and are a promising new addition to the drug delivery platforms currently in use. The investigators also recently used the DNA origami nanoparticles to fine tune the spatial presentation of immunogens to study the impact on B cell activation. These studies are an important step towards the rational design of vaccines for a variety of infectious agents. To elucidate the parameters for optimizing the delivery efficiency of lipid nanoparticles (LNPs), Buschmann, Paige and colleagues have devised methods for predicting and experimentally validating the pKa of LNPs based on the structure of the ionizable lipids used to formulate the LNPs. These studies may pave the way for the development of new LNP delivery vehicles that have reduced systemic distribution and improved endosomal release of their cargo post administration. To better understand protein-protein interactions and identify potential drug targets that disrupt such interactions, Luchini and colleagues have developed a methodology that identifies contact points between proteins using small molecule dyes. The dye molecules noncovalently bind to the accessible surfaces of a protein complex with very high affinity, but are excluded from contact regions. When the complex is denatured and digested with trypsin, the exposed regions covered by the dye do not get cleaved by the enzyme, whereas the contact points are digested. The resulting fragments can then be identified using mass spectrometry. The data generated can serve as the basis for designing small molecules and peptides that can disrupt the formation of protein complexes involved in disease processes. For example, using peptides based on the interleukin 1 receptor accessory protein (IL-1RAcP), Luchini, Liotta, Paige and colleagues disrupted the formation of IL-1/IL-R/IL-1RAcP complex and demonstrated that the inhibition of complex formation reduced the inflammatory response to IL-1B. Working on the discovery of novel antimicrobial agents, Bishop, van Hoek and colleagues have discovered a number of antimicrobial peptides from reptiles and other species. DRGN-1, is a synthetic peptide based on a histone H1-derived peptide that they had identified from Komodo Dragon plasma. DRGN-1 was shown to disrupt bacterial biofilms and promote wound healing in an animal model. The peptide, along with others, is being developed and tested in preclinical studies. Other research by van Hoek and colleagues focuses on in silico antimicrobial peptide discovery, screening of small molecules for antibacterial properties, as well as assessment of diffusible signal factors (DFS) as future therapeutics. The above examples provide insight into the cutting-edge studies undertaken by GMU scientists to develop novel methodologies and platform technologies important to drug discovery.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS2011

Constitutive Soil Properties for Mason Sand and Kennedy Space Center

Accurate soil models are required for numerical simulations of land landings for the Orion Crew Exploration Vehicle (CEV). This report provides constitutive material models for two soil conditions at Kennedy Space Center (KSC) and four conditions of Mason Sand. The Mason Sand is the test sand for LaRC s drop tests and swing tests of the Orion. The soil models are based on mechanical and compressive behavior observed during geotechnical laboratory testing of remolded soil samples. The test specimens were reconstituted to measured in situ density and moisture content. Tests included: triaxial compression, hydrostatic compression, and uniaxial strain. A fit to the triaxial test results defines the strength envelope. Hydrostatic and uniaxial tests define the compressibility. The constitutive properties are presented in the format of LSDYNA Material Model 5: Soil and Foam. However, the laboratory test data provided can be used to construct other material models. The soil models are intended to be specific to the soil conditions they were tested at. The two KSC models represent two conditions at KSC: low density dry sand and high density in-situ moisture sand. The Mason Sand model was tested at four conditions which encompass measured conditions at LaRC s drop test site.

Thomas, Michael A.↗
DOE OSTI2022

Mason–Weaver theory: Revised and extended for a semi-infinite domain

Mason and Weaver developed equations to describe small particles settling under the influence of gravity and Brownian motion, including the limiting case for an infinitely deep suspension. We encountered this common convection–diffusion equation and no-flux boundary conditions in a model for dynamics of adsorbed polymers in dead end pores of a depolymerization catalyst. Close examination reveals that the Mason–Weaver solution is not correct for the infinite domain with a non-uniform initial condition. In this paper, we obtain the time dependent Green’s function for the no flux boundary condition and also for a more general reactive boundary condition. We demonstrate how the results provide solutions, via superposition, which provide solutions for several boundary conditions and all initial conditions.

Chen, Ziqiu↗
NASA NTRS1979

Lidar temperature profiling: Performance simulations of Masons method

Several methods of using lasers to measure atmospheric temperature profiles were described. Mason's suggestion was analyzed here to assess its capabilities for various lidar configurations. Temperatures were inferred from a measure of the Boltzmann distribution of rotational states in one of the vibrational bands of O2. Differential absorption was measured using three tunable, narrowband pulsed lasers. The outputs of two were tuned to wavelengths at the centers of absorption lines at either end of a particular branch in the band. The third wave-length was in a region of no absorption; its lidar return measured only the atmospheric backscatter, and therefore allowed calculations of the absorption coefficients at the other two wavelengths as a function of altitude. From the ratio of the two line absorption coefficients plus a priori knowledge of the line parameters, the temperature-altitude profile were calculated.

Schwemmer, G. K.↗
NASA NTRS1979

Lidar temperature profiling - Performance simulations of Mason's method

In Mason's method (1975) atmospheric temperatures are inferred from a measure of the Boltzmann distribution of rotational states in one of the vibrational bands of O2. Differential absorption is measured using three tunable, narrowband pulse lasers. The outputs of two are tuned to wavelengths at the centers of absorption lines at either end of a particular branch in the band; the third wavelength is in a region of no absorption. The temperature-altitude profile can be calculated from the ratio of the two line absorption coefficients plus a priori knowledge of the line parameters. In the present paper, computer simulations of various lidar configurations are made, using different line pairs in the atmospheric bands of O2 (approximately 630, 690, and 760 nm). Simulated results are presented for temperature profiles measured from a Space Shuttle lidar.

Schwemmer, G. K.↗
NASA NTRS1985

The Crab Nebula and related supernova remnants; Proceedings of the Workshop, George Mason University, Fairfax, VA, October 11, 12, 1984

Papers are presented on the Crab Nebula's composition, helium distribution, outer structure and jet, and evolution. Attention is given to line emission from supernova remnants and charge transfer reactions, a magnetohydrodynamic model of the Crab Nebula and its radiation, inferences made using data on the pulsed flux from the crab pulsar, a new interpretation of the crab pulsar X-ray interpulse radiation, and evolutionary models of the Crab Nebula's progenitor. Other topics include the evolution of the centimeter flux of 3C58 and the Crab Nebula, a search for a shock wave around the Crab Nebula, high resolution radio studies of the Crab Nebula, supernova shell structure, and the nature of the remnant 0540-693 and its implications for the study of crablike remnants. Papers are also presented on X-ray observations of: Crab-like remnants, the Crab Nebula, the Vela X region, W28, and 3C400.2. Other papers include the 50 millisecond pulsar in the Large Magellanic Cloud and the X-ray pulse emission mechanism, optical emission from the plerionic core of CTB 80, and one-arcminute resolution observations of W50.

Kafatos, M. C.↗
NASA NTRS1986

Astrophysics of brown dwarfs; Proceedings of the Workshop, George Mason University, Fairfax, VA, Oct. 14, 15, 1985

Various reports on theoretical and observational studies of brown dwarfs (BDs) are presented. The topics considered include: astrometric detection of BDs, search for substellar companions to nearby stars using IR imaging, constraints on BD mass function from optical and IR searches, properties of stellar objects near the main sequence mass limit, search for low-mass stellar companions with the HF precision velocity technique, dynamical search for substellar objects, search for BDs in the IRAS data base, deep CCD survey for low mass stars in the disk and halo, the Berkeley search for a faint solar companion, the luminosity function for late M stars, astronomic search for IR dwarfs, and the role of the Space Telescope in the detection of BDs. Also addressed are: theoretical significance of BDs, evolution of super-Jupiters, compositional indicators in IR spectra of BDs, evolution of BDs and the evolutionary status of VB8B, the position of BDs on universal diagrams, theoretical determination of the minimum protostellar mass, Population II BDs and dark halos.

Kafatos, Minas C.↗
NASA NTRS2015

Preliminary Flight Deck Observations During Flight in High Ice Water Content Conditions

In 2006, Mason et al. identified common observations that occurred in engine power-loss events attributed to flight in high concentrations of ice crystals. Observations included light to moderate turbulence, precipitation on the windscreen (often reported as rain), aircraft total temperature anomalies, lack of significant airframe icing, and no flight radar echoes at the location and altitude of the engine event. Since 2006, Mason et al. and others have collected information from pilots who experienced engine power-loss events via interviews and questionnaires to substantiate earlier observations and support event analyses. In 2011, Mason and Grzych reported that vertical acceleration data showed increases in turbulence prior to engine events, although the turbulence was usually light to moderate and not unique to high ice water content (HIWC) clouds. Mason concluded that the observation of rain on the windscreen was due to melting of ice high concentrations of ice crystals on the windscreen, coalescing into drops. Mason also reported that these pilot observations of rain on the windscreen were varied. Many pilots indicated no rain was observed, while others observed moderate rain with unique impact sounds. Mason concluded that the variation in the reports may be due to variation in the ice concentration, particle size, and temperature.

Wind Tunnel Tests↗
NASA NTRS2003

Dynamic Turbulence Modelling in Large-eddy Simulations of the Cloud-topped Atmospheric Boundary Layer

The use of large eddy simulation, or LES, to study the atmospheric boundary layer dates back to the early 1970s when Deardor (1972) used a three-dimensional simulation to determine velocity and temperature scales in the convective boundary layer. In 1974 he applied LES to the problem of mixing layer entrainment (Deardor 1974) and in 1980 to the cloud-topped boundary layer (Deardor 1980b). Since that time the LES approach has been applied to atmospheric boundary layer problems by numerous authors. While LES has been shown to be relatively robust for simple cases such as a clear, convective boundary layer (Mason 1989), simulation of the cloud-topped boundary layer has proved more of a challenge. The combination of small length scales and anisotropic turbulence coupled with cloud microphysics and radiation effects places a heavy burden on the turbulence model, especially in the cloud-top region. Consequently, over the past few decades considerable effort has been devoted to developing turbulence models that are better able to parameterize these processes. Much of this work has involved taking parameterizations developed for neutral boundary layers and deriving corrections to account for buoyancy effects associated with the background stratification and local buoyancy sources due to radiative and latent heat transfer within the cloud (see Lilly 1962; Deardor 1980a; Mason 1989; MacVean & Mason 1990, for example). In this paper we hope to contribute to this effort by presenting a number of turbulence models in which the model coefficients are calculated dynamically during the simulation rather than being prescribed a priori.

Kirkpatrick, M. P.↗
DOE OSTI2023

Rheo-electric measurements of carbon black suspensions containing polyvinylidene difluoride in N -methyl-2-pyrrolidone

Lithium-ion battery cathode slurries have a microstructure that depends sensitively on how they are processed due to carbon black's (CB) evolving structure when subjected coating flows. While polyvinylidene difluoride (PVDF), one of the main components of the cathode slurry, plays an important role in modifying the structure and rheology of CB, a quantitative understanding is lacking. In this work, we explore the role of PVDF in determining the structural evolution of Super C65 CB in N-methyl-2-pyrrolidinone (NMP) with rheo-electric measurements. We find that PVDF enhances the viscosity of NMP resulting in a more extensive structural erosion of CB agglomerates with increasing polymer concentration and molecular weight. We also show that the relative viscosity of all suspensions can be collapsed by the fluid Mason number (Mnf), which compares the hydrodynamic forces imposed by the medium to cohesive forces holding CB agglomerates together. Using simultaneous rheo-electric measurements, we find at high Mnf, the dielectric strength (Δε) scales with Mnf, and the power-law scaling can be quantitatively predicted by considering the self-similar break up of CB agglomerates. The collapse of the relative viscosity and scaling of Δε both suggest that PVDF increases the hydrodynamic force of the suspending medium without directly changing the CB agglomerate structure. These findings are valuable for optimizing the rheology of lithium ion battery cathode slurries. We also anticipate that these findings can be extended to understand the microstructure of similar systems under flow.

Mechanics↗
DOE OSTI2022

Operational and Mission Highlights (A Monthly Summary of Top Achievements, November 2022)

On November 16, Los Alamos National Laboratory Director Thom Mason answered questions from the Defense Nuclear Facilities Safety Board (DNFSB) at a public hearing in Santa Fe about the safety of operations at the Laboratory’s plutonium facility and the pit production mission. Mason participated on a panel along with National Nuclear Security Administration’s (NNSA) Administrator Jill Hruby, Deputy NNSA Administrator James McConnell, and NNSA Los Alamos Field Office Manager Ted Wyka.

98 NUCLEAR DISARMAMENT, SAFEGUARDS, AND PHYSICAL P↗
DOE OSTI2023

A review of the shear rheology of carbon black suspensions

The microstructural link to the rheology of carbon black suspensions has recently become clear as a result of advances in computational and experimental methods. This understanding reveals the important role of the restructuring, build-up, and break-up of carbon black agglomerates in simple shear, rationalized by a dimensionless balance of the hydrodynamic forces acting to break the agglomerates apart against the cohesive forces holding them together (i.e., the Mason number). The Mason number not only can predict the origin of reversible thixotropy seen in carbon black suspensions observed at higher shear intensities, but can also be used to rationalize the evolution of microstructure at lower shear intensities. This review focuses on carbon black suspension behavior, but the insights derived from carbon black suspensions are broadly applicable to a diverse class of soft matter including colloidal gels relevant to a variety of applications.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
NASA NTRS1974

ICR study of nonreactive ion-molecule collision rate constants for Cl/-/ and Cr/CO/5/-/

Determination of experimental momentum transfer rate constants for systems of Cl(-) and Cr(CO)5(-) ions by means of an ion cyclotron resonance (ICR) line-broadening technique. It is found that in the pure polarization limit of small ion/large neutral collisions the Langevin ion mobility theory gives good agreement with experimental results. A comparison of isotropic and anisotropic neutral systems suggests that a correction for the anisotropic systems is necessary. Beyond the pure polarization limit the Langevin theory gives poor predictions for ion mobilities. The adjustable parameter, gamma, of the Mason-Schamp (12-6-4) potential function permits unique solution of the ion mobility for Cr(CO)5(-) in a wide range of neutral gases. The large values of gamma obtained for most of these systems imply, in terms of the Mason-Schamp theory, that the r to the minus 6th power contribution to the potential function is significant.

Dymerski, P. P.↗
NASA NTRS2016

The OMICS of Sports & Space: How Genomics is Transforming Both Fields

Join top 10 New York Times Bestseller “The Sports Gene” author David Epstein and NASA Twins Study investigator Christopher E. Mason, Ph.D., in the debate as old as physical competition—nature versus nurture. From personal experience, Epstein tackles the great debate and traces how far science has come in solving this timeless riddle, and how genetics has entered into the field of sports. He’s an investigative science reporter for ProPublica and longtime contributor to Sports Illustrated. Epstein will share insights into performance-enhancing drugs, the lucky genetics that separate a professional athlete from a less talented athlete, and his research into the death of a friend with Hypertrophic Cardiomyopathy (HCM).From an epigenomic viewpoint, Mason examines the benefits and risks for astronauts who face extreme spaceflight conditions and what it means for the future of human space travel. He is an associate professor in the Department of Physiology and Biophysics, The Feil Family Brain and Mind Research Institute (BMRI) & The Institute for Computational Biomedicine at Weill Cornell Medicine. He is also part of the Tri-Institutional Program on Computational Biology and a Medicine Fellow of Genomics, Ethics, and Law in the Information Society Project at Yale Law School.The study of omics shows tremendous potential in prevention, diagnosis and treatment of injuries and diseases but genetic discrimination and molecular privacy concerns are raised in both sports and space.

Reeves, Katherine↗