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Results for “linear growth factor G”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 19 records
All sourcesNASA NTRSDOE OSTI
DOE OSTI2011

Cosmology without cosmic variance

The growth of structures in the Universe is described by a function G that is predicted by the combination of the expansion history of the Universe and the laws of gravity within it. We examine the improvements in constraints on G that are available from the combination of a large-scale galaxy redshift survey with a weak gravitational lensing survey of background sources. We describe a new combination of such observations that in principle this yields a measure of the growth rate that is free of sample variance, i.e. the uncertainty in G can be reduced without bound by increasing the number of redshifts obtained within a finite survey volume. The addition of background weak lensing data to a redshift survey increases information on G by an amount equivalent to a 10-fold increase in the volume of a standard redshift-space distortion measurement - if the lensing signal can be measured to sub-per cent accuracy. This argues that a combined lensing and redshift survey over a common low-redshift volume of the Universe is a more powerful test of general relativity than an isolated redshift survey over larger volume at high redshift, especially as surveys begin to cover most of the available sky.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2018

Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor

Receptor tyrosine kinases (RTKs) typically contain multiple autophosphorylation sites in their cytoplasmic domains. Once activated, these autophosphorylation sites can recruit downstream signaling proteins containing Src homology 2 (SH2) and phosphotyrosine-binding (PTB) domains, which recognize phosphotyrosine-containing short linear motifs (SLiMs).

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2016

Electric field stimulated growth of Zn whiskers

We have investigated the impact of strong (∼10{sup 4} V/cm) electric fields on the development of Zn whiskers. The original samples, with considerable whisker infestation were cut from Zn-coated steel floors and then exposed to electric fields stresses for 10-20 hours at room temperature. We used various electric field sources, from charges accumulated in samples irradiated by: (1) the electron beam of a scanning electron microscope (SEM), (2) the electron beam of a medical linear accelerator, and (3) the ion beam of a linear accelerator; we also used (4) the electric field produced by a Van der Graaf generator. In all cases, the exposed samples exhibited a considerable (tens of percent) increase in whiskers concentration compared to the control sample. The acceleration factor defined as the ratio of the measured whisker growth rate over that in zero field, was estimated to approach several hundred. The statistics of lengths of e-beam induced whiskers was found to follow the log-normal distribution known previously for metal whiskers. The observed accelerated whisker growth is attributed to electrostatic effects. These results offer promise for establishing whisker-related accelerated life testing protocols.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗
DOE OSTI2015

TU-CD-BRB-07: Identification of Associations Between Radiologist-Annotated Imaging Features and Genomic Alterations in Breast Invasive Carcinoma, a TCGA Phenotype Research Group Study

Purpose: To determine associations between radiologist-annotated MRI features and genomic measurements in breast invasive carcinoma (BRCA) from the Cancer Genome Atlas (TCGA). Methods: 98 TCGA patients with BRCA were assessed by a panel of radiologists (TCGA Breast Phenotype Research Group) based on a variety of mass and non-mass features according to the Breast Imaging Reporting and Data System (BI-RADS). Batch corrected gene expression data was obtained from the TCGA Data Portal. The Kruskal-Wallis test was used to assess correlations between categorical image features and tumor-derived genomic features (such as gene pathway activity, copy number and mutation characteristics). Image-derived features were also correlated with estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2/neu) status. Multiple hypothesis correction was done using Benjamini-Hochberg FDR. Associations at an FDR of 0.1 were selected for interpretation. Results: ER status was associated with rim enhancement and peritumoral edema. PR status was associated with internal enhancement. Several components of the PI3K/Akt pathway were associated with rim enhancement as well as heterogeneity. In addition, several components of cell cycle regulation and cell division were associated with imaging characteristics.TP53 and GATA3 mutations were associated with lesion size. MRI features associated with TP53 mutation status were rim enhancement and peritumoral edema. Rim enhancement was associated with activity of RB1, PIK3R1, MAP3K1, AKT1,PI3K, and PIK3CA. Margin status was associated with HIF1A/ARNT, Ras/ GTP/PI3K, KRAS, and GADD45A. Axillary lymphadenopathy was associated with RB1 and BCL2L1. Peritumoral edema was associated with Aurora A/GADD45A, BCL2L1, CCNE1, and FOXA1. Heterogeneous internal nonmass enhancement was associated with EGFR, PI3K, AKT1, HF/MET, and EGFR/Erbb4/neuregulin 1. Diffuse nonmass enhancement was associated with HGF/MET/MUC20/SHIP, and HGF/MET/RANBP9. Linear nonmass enhancement was associated with PIK3R1 and AKT activity. Conclusion: MRI-genomic association analysis revealed that several BRCA-associated gene features were associated with radiologist-annotated image features.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2013

Integration of microplasma with transmission electron microscopy: Real-time observation of gold sputtering and island formation

An in situ platform for characterizing plasma-materials interactions at the nanoscale in the transmission electron microscope (TEM) has been demonstrated. Integrating a DC microplasma device, having plane-parallel electrodes with a 25 nm thick Au film on both the cathode and anode and operating in 760 Torr of Ar, within a TEM provides real-time observation of Au sputtering and island formation with a spatial resolution of , 100 nm. Analyses of TEM and atomic force microscopy images show the growth of Au islands to proceed by a Stranski-Krastanov process at a rate that varies linearly with the discharge power and is approximately a factor of 3 larger than the predictions of a DC plasma sputtering model. The experiments reported here extend in situ TEM diagnostics to plasma-solid and plasma-liquid interactions.

METAMATERIALS↗
DOE OSTI2013

Hydrodynamic simulations of long-scale-length two-plasmon-decay experiments at the Omega Laser Facility

Direct-drive-ignition designs with plastic CH ablators create plasmas of long density scale lengths (L{sub n} {>=} 500 {mu}m) at the quarter-critical density (N{sub qc}) region of the driving laser. The two-plasmon-decay (TPD) instability can exceed its threshold in such long-scale-length plasmas (LSPs). To investigate the scaling of TPD-induced hot electrons to laser intensity and plasma conditions, a series of planar experiments have been conducted at the Omega Laser Facility with 2-ns square pulses at the maximum laser energies available on OMEGA and OMEGA EP. Radiation-hydrodynamic simulations have been performed for these LSP experiments using the two-dimensional hydrocode draco. The simulated hydrodynamic evolution of such long-scale-length plasmas has been validated with the time-resolved full-aperture backscattering and Thomson-scattering measurements. draco simulations for CH ablator indicate that (1) ignition-relevant long-scale-length plasmas of L{sub n} approaching {approx}400 {mu}m have been created; (2) the density scale length at N{sub qc} scales as L{sub n}({mu}m) Asymptotically-Equal-To (R{sub DPP} Multiplication-Sign I{sup 1/4}/2); and (3) the electron temperature T{sub e} at N{sub qc} scales as T{sub e}(keV) Asymptotically-Equal-To 0.95 Multiplication-Sign {radical}(I), with the incident intensity (I) measured in 10{sup 14} W/cm{sup 2} for plasmas created on both OMEGA and OMEGA EP configurations with different-sized (R{sub DPP}) distributed phase plates. These intensity scalings are in good agreement with the self-similar model predictions. The measured conversion fraction of laser energy into hot electrons f{sub hot} is found to have a similar behavior for both configurations: a rapid growth [f{sub hot} Asymptotically-Equal-To f{sub c} Multiplication-Sign (G{sub c}/4){sup 6} for G{sub c} < 4] followed by a saturation of the form, f{sub hot} Asymptotically-Equal-To f{sub c} Multiplication-Sign (G{sub c}/4){sup 1.2} for G{sub c} {>=} 4, with the common wave gain is defined as G{sub c}=3 Multiplication-Sign 10{sup -2} Multiplication-Sign I{sub qc}L{sub n}{lambda}{sub 0}/T{sub e}, where the laser intensity contributing to common-wave gain I{sub qc}, L{sub n}, T{sub e} at N{sub qc}, and the laser wavelength {lambda}{sub 0} are, respectively, measured in [10{sup 14} W/cm{sup 2}], [{mu}m], [keV], and [{mu}m]. The saturation level f{sub c} is observed to be f{sub c} Asymptotically-Equal-To 10{sup -2} at around G{sub c} Asymptotically-Equal-To 4. The hot-electron temperature scales roughly linear with G{sub c}. Furthermore, to mitigate TPD instability in long-scale-length plasmas, different ablator materials such as saran and aluminum have been investigated on OMEGA EP. Hot-electron generation has been reduced by a factor of 3-10 for saran and aluminum plasmas, compared to the CH case at the same incident laser intensity. draco simulations suggest that saran might be a better ablator for direct-drive-ignition designs as it balances TPD mitigation with an acceptable hydro-efficiency.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2018

Study of ion-gyroscale fluctuations in low-density L-mode plasmas heated by NBI on KSTAR

Broadband density fluctuations with peak frequency ranging from 150 to 400 kHz were measured using a multichannel microwave imaging reflectometer in core region of the low-density L-mode plasmas heated by neutral beam injection on KSTAR. These fluctuations have been studied by comparing the dominant mode scales estimated from the measurement with those predicted from linear gyrokinetic simulation. The measured poloidal wavenumbers are qualitatively comparable to those of the 'fastest growing modes' from simulations, whereas they are larger than those of the 'transport-dominant modes' by about a factor of three. The agreement on wavenumbers between the measurement and linear simulation (for the fastest growing modes) is probably due to sufficiently weak $E \times B$ flow shear compared to the maximum linear growth rate. Meanwhile, the transport-dominant modes seem to be related to the fluctuations in lower frequencies (~80–150 kHz) observed in some of the measurement.

Physics↗
NASA NTRS1982

Fracture mechanics criteria for turbine engine hot section components

The application of several fracture mechanics data correlation parameters to predicting the crack propagation life of turbine engine hot section components was evaluated. An engine survey was conducted to determine the locations where conventional fracture mechanics approaches may not be adequate to characterize cracking behavior. Both linear and nonlinear fracture mechanics analyses of a cracked annular combustor liner configuration were performed. Isothermal and variable temperature crack propagation tests were performed on Hastelloy X combustor liner material. The crack growth data was reduced using the stress intensity factor, the strain intensity factor, the J integral, crack opening displacement, and Tomkins' model. The parameter which showed the most effectiveness in correlation high temperature and variable temperature Hastelloy X crack growth data was crack opening displacement.

Meyers, G. J.↗
DOE OSTI2012

Volume Changes After Stereotactic LINAC Radiotherapy in Vestibular Schwannoma: Control Rate and Growth Patterns

Purpose: The purpose of this study was to evaluate the control rate of vestibular schwannomas (VS) after treatment with linear accelerator (LINAC)-based stereotactic radiosurgery (SRS) or radiotherapy (SRT) by using a validated volumetric measuring tool. Volume-based studies on prognosis after LINAC-based SRS or SRT for VS are reported scarcely. In addition, growth patterns and risk factors predicting treatment failure were analyzed. Materials and Methods: Retrospectively, 37 VS patients treated with LINAC based SRS or SRT were analyzed. Baseline and follow-up magnetic resonance imaging scans were analyzed with volume measurements on contrast enhanced T1-weighted magnetic resonance imaging. Absence of intervention after radiotherapy was defined as 'no additional intervention group, ' absence of radiological growth was defined as 'radiological control group. ' Significant growth was defined as a volume change of 19.7% or more, as calculated in a previous study. Results: The cumulative 4-year probability of no additional intervention was 96.4% {+-} 0.03; the 4-year radiological control probability was 85.4% {+-} 0.1). The median follow-up was 40 months. Overall, shrinkage was seen in 65%, stable VS in 22%, and growth in 13%. In 54% of all patients, transient swelling was observed. No prognostic factors were found regarding VS growth. Previous treatment and SRS were associated with transient swelling significantly. Conclusions: Good control rates are reported for LINAC based SRS or SRT in VS, in which the lower rate of radiological growth control is attributed to the use of the more sensitive volume measurements. Transient swelling after radiosurgery is a common phenomenon and should not be mistaken for treatment failure. Previous treatment and SRS were significantly associated with transient swelling.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
NASA NTRS1994

An Analytical Tool for Fracture Control

The structural integrity of critical NASA space flight hardware is ensured through a damage tolerance program which is dictated in the fracture control requirements. The goal of a fracture control program is to ensure proper material selection and control, control of working stress levels, use of fracture resistant design concepts, manufacturing process control, and the use of qualified inspection procedures. The damage tolerance philosophy assumes that all components contain initial defects and the damage accumulation process is thus entirely crack propagation. The service capability of fracture critical components is determined by analysis and/or test. A large percentage of NASA fracture critical hardware is certified by analysis only and it is therefore imperative that the analysis code utilized contain the latest state of the art technology. Not all space contractors and vendors are able to develop and maintain an analysis code which meets this requirement. A response to this need has been fulfilled by the development of the NASA/FLAGRO (NASGRO) fracture mechanics code here at the Johnson Space Center. The NASGRO code is based primarily in Linear Elastic Fracture Mechanics (LEFM) and is continually updated to meet to needs of the user community. Development assistance comes from other NASA centers as well as the European Space Agency (ESA). The code currently has a vast materials data file (over 350 different entries) which defines the material strength, fracture toughness, crack growth rate, and crack growth threshold. The code also allows for user defined inputs of data from other sources. The code also provides a large library of stress intensity factor solutions for numerous geometries and loading conditions.

Patin, Raymond M.↗
NASA NTRS1991

Interaction of a finite-length ion beam with a background plasma - Reflected ions at the quasi-parallel bow shock

The coupling of a finite-length, field-aligned, ion beam with a uniform background plasma is investigated using one-dimensional hybrid computer simulations. The finite-length beam is used to study the interaction between the incident solar wind and ions reflected from the earth's quasi-parallel bow shock, where the reflection process may vary with time. The coupling between the reflected ions and the solar wind is relevant to ion heating at the bow shock and possibly to the formation of hot, flow anomalies and re-formation of the shock itself. Consistent with linear theory, the waves which dominate the interaction are the electromagnetic right-hand polarized resonant and nonresonant modes. However, in addition to the instability growth rates, the length of time that the waves are in contact with the beam is also an important factor in determining which wave mode will dominate the interaction. It is found that interaction will result in strong coupling, where a significant fraction of the available free energy is converted into thermal energy in a short time, provided the beam is sufficiently dense or sufficiently long.

Onsager, T. G.↗
DOE OSTI2020

Magnetic shear effect on plasma transport at T e / T i ~ 1 through electron cyclotron heating in DIII-D plasmas

The effect of magnetic shear on plasma transport for an electron to ion temperature ratio ( T e / T i ) near unity has been explored in DIII-D utilizing electron cyclotron heating (ECH). Previous reports showed that significant confinement degradation occurred at T e / T i ~ 1 in positive shear (PS) plasmas in DIII-D, whereas reduced confinement degradation was observed in negative central shear (NCS) plasmas. In this study, plasma transport in weak magnetic shear (WS) plasmas with ECH is investigated and compared with that in NCS and PS plasmas. Here the magnetic shears ($\hat s$) are $\hat s$ > 0.5, ~0 and <-0.1 in the core region (ρ~ 0.3–0.4) of PS, WS and NCS plasmas, respectively, and flat or negative inside ρ~ 0.4 in the WS and NCS plasmas. Weak magnetic shear is found to be effective in minimizing degradation of ion thermal confinement as T e / T i increases through ECH application, and an improved confinement factor of H 98y2 ~ 1.2 is maintained, similar to NCS plasmas. At T e / T i ~ 1, the ion thermal diffusivity around an internal transport barrier decreases when changing the magnetic shear from positive to weak or negative shear. Also, reduced local particle and momentum transport was indicated by steeper density and toroidal rotation profiles in the weak and negative shear regimes. Linear gyrokinetic simulations predict little change in growth rates of low-k turbulence with ECH application in the WS and NCS plasmas, which is consistent with the transport and profile analyses.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
NASA NTRS1975

Crack growth in bonded elastic half planes

Two solutions were developed for the two dimensional problem of bonded linearly elastic half-planes. For each solution, numerical results are presented for the stress intensity factors, strain energy release rate, stresses, and displacements. The behavior predicted by the studies was investigated experimentally using polymers for the material pairs. Close agreement was found for the critical stress intensity factor at fracture for the perpendicular crack near the interface. Fracture along the interface proved to be inconclusive due to difficulties in obtaining a brittle bond. Some interesting and predictable behavior regarding the potential for the crack to cross the interface was observed and is discussed.

Goree, J. G.↗
DOE OSTI2022

Constraining scale dependent growth with redshift surveys

Ongoing and future redshift surveys have the capability to measure the growth rate of large scale structure at the percent level over a broad range of redshifts, tightly constraining cosmological parameters. Beyond general relativity, however, the growth rate in the linear density perturbation regime can be not only redshift dependent but scale dependent, revealing important clues to modified gravity. We demonstrate that a fully model independent approach of binning the gravitational strength G eff (k,z) matches scalar-tensor results for the growth rate fσ 8 (k,z) to 0.02%–0.27% rms accuracy. For data of the quality of the Dark Energy Spectroscopic Instrument (DESI) we find the bin values can be constrained to 1.4%–28%. We also explore the general scalar-tensor form, constraining the amplitude and past and future scalaron mass/shape parameters. Perhaps most interesting is the strong complementarity of low redshift peculiar velocity data with DESI-like redshift space distortion measurements, enabling improvements up to a factor 6–7 on 2D joint confidence contour areas. Finally, we quantify some issues with gravity parametrizations that do not include all the key physics.

79 ASTRONOMY AND ASTROPHYSICS↗
NASA NTRS1992

Green and non-green callus induction from excised rice (Oryza sativa) embryos: effects of exogenous plant growth regulators

Calli were induced either from excised rice embryos or from whole seeds in the presence of 1 to 5 mg l-1 NAA. After 12 days of culture, calli were induced only from excised rice embryos. We found that excised embryos accumulated NAA up to 6 times higher concentration than did whole seeds. In the presence of 1 to 5 mg l-1 NAA and 2 to 10 mg l-1 kinetin, chlorophyllous calli were induced from excised rice embryos. Chlorophyll contents in the callus tissue increased with increasing kinetin concentration while percent callus induction decreased. The total chlorophyll content was linearly correlated with the ratio of kinetin to NAA in the medium.

NASA Discipline Number 40-50↗
DOE OSTI2022

Verification and validation of linear gyrokinetic and kinetic-MHD simulations for internal kink instability in DIII-D tokamak

Here, verification and linear validation of the internal kink instability in tokamak have been performed for both gyrokinetic (GTC) and kinetic-MHD codes (GAM-solver, M3D-C1-K, NOVA, XTOR-K). Using realistic magnetic geometry and plasma profiles from the same equilibrium reconstruction of the DIII-D shot #141216, these codes exhibit excellent agreement for the growth rate and mode structure of the internal kink mode when all kinetic effects are suppressed. The simulated radial mode structures, obtained from linear simulations, are in reasonable agreement with the normalised electron cyclotron emission measurement after adjusting, within the experimental uncertainty, the safety factor q = 1 flux-surface location in the equilibrium reconstruction. Compressible magnetic perturbations strongly destabilize the kink, while poloidal variations of the equilibrium current density reduce the growth rate of the kink. Furthermore, kinetic effects of thermal ions are found to decrease the kink growth rate in kinetic-MHD simulations, but increase the kink growth rate in gyrokinetic simulations, due to the additional drive of the ion temperature gradient and parallel electric field. Kinetic thermal electrons are found to have negligible effects on the internal kink instability.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2020

On hybrid scenarios in KSTAR

We report the status of hybrid scenario experiments in Korea Superconducting Tokamak Advanced Research (KSTAR). The hybrid scenario is defined as stationary discharges with ${\beta _{\rm{N}}}$ $ \geqslant $ 2.4 and ${H_{89}}$ $ \geqslant $ 2.0 at ${q_{95}}$ < 6.5 without or with very mild sawtooth activities in KSTAR. It is being developed towards reactor-relevant conditions. High performance of ${\beta _{\rm{N}}} \lesssim 3.0$, ${H_{89}} \lesssim 2.4$ and G-factor ($ \equiv {\beta _{\rm{N}}}{H_{89}}/q_{95}^2$) $ \lesssim 0.4$6 has been achieved and sustained for $ \gtrsim 40{{\tau }_{\text{E}}}$ at ne/nGW ~ 0.7 with heating power of $ \lesssim $5 MW. Some KSTAR hybrid discharges exhibit a unique feature of a slow transition from conventional H-mode to hybrid mode after the third neutral beam injection. The reason for the confinement enhancement is extensively studied in this transition period of a representative discharge exhibiting a common feature of KSTAR hybrid scenarios. 0D performance analysis with magnetohydrodynamic activities, 1D kinetic profile dynamics, power balance analysis, linear gyro-kinetic analysis and edge pedestal stability analysis were conducted. The enhancement is thought to be from both the core and the pedestal. The improvement in the core region of the ion energy channel is observed from the linear gyro-kinetic analysis considering the electromagnetic, the fast ion, the Shafranov shift, ${\it{\omega }_{E \times B}}$, and the magnetic shear effect. The electromagnetic finite $\beta $ stabilisation plays a role in the inner core region at ${\rho _{\rm{tor}}}\sim0.35$ together with the fast ion effect. The alpha stabilisation effect is also found at ${\rho _{\rm{tor}}}\sim0.5$. ${\omega _{E \times B}}$, which could reduce the linear growth of the ion temperature gradient mode in the outer core region at ${\rho _{\rm{tor}}}\sim0.5 - 0.7$ with the highest contribution from the toroidal rotation. Furthermore, regarding the improvement in the pedestal, Shafranov shift broadens the stability boundary of the pedestal in support of the diamagnetic effect. The pedestal height and width could be reproduced by the EPED model, while a realistic current profile is used to calculate the internal inductance for Shafranov shift. Based on these findings, a comprehensive confinement enhancement mechanism has been proposed by considering the core-edge interplay.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2024

Complete quasilinear model for the acceleration-driven lower hybrid drift instability and a computational assessment of its validity

A complete quasilinear model is derived for the electrostatic acceleration-driven lower hybrid drift instability in a uniform two-species low-beta plasma in which current is perpendicular to the background magnetic field. The model consists of coupled nonlinear velocity space diffusion equations for the volume-averaged ion and electron distribution functions. Each species' diffusion coefficient depends on a time-evolving spectral density of the electric-field energy per unit volume and a time-evolving dispersion relation. The dispersion relation is expressed analytically in integral form without the use of asymptotic limits and applies to arbitrary distribution functions, so long as they can be expressed as a function of one velocity coordinate, e.g., f⁡(vy) or f⁡(v⊥). The quasilinear model conserves energy and is complete in that it fully describes the evolution of the distribution functions, including resonant and nonresonant particle-wave interactions, while accounting for distribution-function-dependent mixed-complex frequencies. Further, the quasilinear diffusion model is solved numerically and self-consistently using a Crank-Nicolson temporal discretization and a second-order finite-volume velocity-space discretization. Numerical solutions are compared to nonlinear fourth-order accurate continuum kinetic Vlasov-Poisson simulations. Evolution of electric-field energy, growth rates, distribution functions, and diffusion coefficients are shown to be in agreement with Vlasov simulations. The quasilinear model is shown to predict anomalous transport terms, like resistivity and heating, to within a factor of order unity. Discrepancies between the quasilinear model and Vlasov simulations are assessed and attributed primarily to lack of damping in the quasilinear description and to the use of unperturbed-orbit susceptibilities in the linear theory dispersion relation. The results illuminate the predictive accuracy of the quasilinear model, place approximate bounds on its validity, and provide much needed vetting of quasilinear theory's ability to predict the nonlinear state of a microturbulent plasma.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗