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TlC is Tetraauricupride structured and crystallizes in the tetragonal P4mm space group. The structure is two-dimensional and consists of one TlC sheet oriented in the (0, 0, 1) direction. Tl3+ is bonded in a rectangular see-saw-like geometry to four equivalent C3- atoms. All Tl–C bond lengths are 2.43 Å. C3- is bonded in a rectangular see-saw-like geometry to four equivalent Tl3+ atoms.
The chief aims in THE SPHINX PROJECT are research of super lepton physics and new detector experiments. At the second phase of THE SPHINX PROJECT, a hybrid TLC-PAIR METER was designed for measuring high energy neutrino sources (E upsilon * TeV), searching high energy muon sources (E mu TeV) and measuring muon group (E mu 1 TeV). The principle of PAIR METER has been already proposed. In this TLC-PAIR METER, electromagnetic shower induced by cosmic ray muons are detected using TL (Thermoluminescence) sheets with position counters.
TlC is Halite, Rock Salt structured and crystallizes in the cubic Fm-3m space group. The structure is three-dimensional. Tl3+ is bonded to six equivalent C3- atoms to form a mixture of edge and corner-sharing TlC6 octahedra. The corner-sharing octahedral tilt angles are 0°. All Tl–C bond lengths are 2.52 Å. C3- is bonded to six equivalent Tl3+ atoms to form a mixture of edge and corner-sharing CTl6 octahedra. The corner-sharing octahedral tilt angles are 0°.
TlC is Tetraauricupride structured and crystallizes in the cubic Pm-3m space group. The structure is three-dimensional. Tl3+ is bonded in a body-centered cubic geometry to eight equivalent C3- atoms. All Tl–C bond lengths are 2.80 Å. C3- is bonded in a body-centered cubic geometry to eight equivalent Tl3+ atoms.
Application of thin-layer chromatographics provides rapid qualitative determination of functional distribution in experimental prepolymer. Functionality distribution is of fundamental importance for it determines; (1) manner in which given carboxyl-terminated prepolymer will cure and (2) physical properties of resulting product.
The complex polar lipids of the hot spring cyanobacterial mat in the 50 to 55 degrees C region of Octopus Spring, Yellowstone National Park, and of thermophilic bacteria cultivated from this or similar habitats, were compared in an attempt to understand the microbial sources of the major lipid biomarkers in this community. Intact complex lipids were analyzed directly by fast atom bombardment mass spectrometry (FAB-MS), two-dimensional thin-layer chromatography (TLC), and combined TLC-FAB-MS. FAB-MS and TLC gave qualitatively similar results, suggesting that the mat contains major lipids most like those of the cyanobacterial isolate we studied, Synechococcus sp. strain Y-7c-s. These include monoglycosyl, diglycosyl, and sulfoquinosovyl diglycerides (MG, DG, and SQ, respectively) and phosphatidyl glycerol (PG). Though Chloroflexus aurantiacus also contains MG, DG, and PG, the fatty acid chain lengths of mat MGs, DGs, and PGs resemble more those of cyanobacterial than green nonsulfur bacterial lipids. FAB-MS spectra of the lipids of nonphototrophic bacterial isolates were distinctively different from those of the mat and phototrophic isolates. The lipids of these nonphototrophic isolates were not detected in the mat, but most could be detected when added to mat samples. The mat also contains major glycolipids and aminophospholipids of unknown structure and origin. FAB-MS and TLC did not always give quantitatively similar results. In particular, PG and SQ may give disproportionately high FAB-MS responses.
Background: Synthetic biology efforts often require high-throughput screening tools for enzyme engineering campaigns. While innovations in chromatographic and mass spectrometry-based techniques provide relevant structural information associated with enzyme activity, these approaches can require cost-intensive instrumentation and technical expertise not broadly available. Moreover, complex workflows and analysis time can significantly impact throughput. To this end, we develop an automated, 96-well screening platform based on thin layer chromatography (TLC) and use it to monitor in vitro activity of a geranylgeranyl reductase isolated from Sulfolobus acidocaldarius (SaGGR). Results: Unreduced SaGGR products are oxidized to their corresponding epoxide and applied to thin layer silica plates by acoustic printing. These derivatives are chromatographically separated based on the extent of epoxidation and are covalently ligated to a chromophore, allowing detection of enzyme variants with unique product distributions or enhanced reductase activity. Herein, we employ this workflow to examine farnesol reduction using a codon-saturation mutagenesis library at the Leu377 site of SaGGR. We show this TLC-based screen can distinguish between fourfold differences in enzyme activity for select mutants and validated those results by GC–MS. Conclusions: With appropriate quantitation methods, this workflow can be used to screen polyprenyl reductase activity and can be readily adapted to analyze broader catalyst libraries whose products are amenable to TLC analysis.
The experimental procedure and aerodynamic force and moment measurements for wind tunnel testing of the three lifting surface configuration (TLC) are described. The influence of nonelliptical lift distributions on lift, drag, and static longitudinal stability are examined; graphs of the lift coefficient versus angle of attack, the pitching moment coefficient, drag coefficient, and lift to drag ratio versus lift coefficient are provided. The TLC data are compared with the conventional tail-aft configuration and the canard-wing configuration; it is concluded that the TLC has better lift and high-lift drag characteristics, lift to drag ratio, and zero-lift moments than the other two configurations. The effects of variations in forward and tail wind incidence angles, gap, stagger, and forward wind span on the drag, lift, longitudinal stability, and zero-lift moments of the configuration are studied.
The effect of prolonged bed rest on the lung function was studied by measuring forced vital capacity (FVC) and total lung capacity (TLC) in normal subjects before, during, and after 11- to 12-day rest periods. It was found that both FVC and TLC increased during bed rest (compared with the ambulatory controls), while residual volume and functional residual capacity of the respiratory system did not change. It is concluded that the increase in TLC by prolonged bed rest is not dependent on alterations in plasma volume.
When utilizing [ 18 F]tetrabutylammonium fluoride ([ 18 F]TBAF) in the synthesis of 18 F-labeled radiotracers for clinical positron emission tomography (PET) imaging, it is necessary to confirm that residual TBA levels in formulated doses do not exceed established specifications (≤2.6 mg per patient dose). Historically this has been accomplished using HPLC, but this is time consuming for short-lived PET radiotracers and limited by the need for expensive equipment. This motivated us to introduce a TLC spot test for determining residual TBA, and we have developed a new method which employs the Dragendorff reagent. Herein we report details of the TLC method and use it to quantify residual TBA in different formulations of 6-[ 18 F]fluoro-DOPA.
Argonne National Laboratory (Argonne) is assisting NorthStar Medical Technologies in the development of a domestic supply of 99 Mo. Specifically, the present study focuses on the production of 99 Mo-feed solution used by the RadioGenix™ 99m Tc generator. During the target-irradiation phase of production, impurities can potentially be introduced into the feed, and can lead to disturbance of ligand- 99m Tc complexation chemistry and contamination of the final radiopharmaceutical that directly interacts with the patient. To address this issue, Argonne performed irradiations and chemical processing to identify whether the potential contamination of He flow with hydrocarbon oil during irradiation affects the radiochemical purity of the final K 2 MoO 4 (K 2 TcO 4 ) in 5M KOH solution. To mimic the conditions of real irradiation at NorthStar, Argonne used its electron linear accelerator and Van de Graaff facilities, heated the target and oil source to >800°C, and controlled oxygen in the presence of He during irradiation. Following irradiation, scanning electron microscopy (SEM) and carbon analysis (CA) were used to detect carbon contamination on the solid targets. The radiochemical purity of the dissolved targets was studied via thin-layer paper chromatography (TLC). As a result of these experiments, small regions of the surface of some irradiated disks were found to be high in carbon, but the total carbon content was still negligible in comparison to the reference sample, which had experienced no irradiation or contact with oil. The summarized results from the SEM, CA, and TLC tests lead to the conclusion that even an excess of oil and heating during irradiation do not affect the radiochemical purity of the final product.
A novel technique has been developed to visualized the thermal performance characteristics of simple low temperature heat pipes and thermosyphons. Copper heat pipes with internal, annular mesh wicks and charged with Refrigerant-12 were externally coated with thermochromic liquid crystal (TLC) paints. The thermally sensitive TLC coating reversibly changes color upon heating and readily permits visual identification of transient and steady state isotherms during low temperature operation. The start-up and operational behaviors of the heat pipe as well as the presence of non-condensible gases can be visually identified through a spectrum of color changes. A brief video demonstration illustrating heat pipe thermal performance characteristics has been developed and illustrates the utility of TLCs for visualizing thermal behavior.
Paints containing thermochromic liquid crystals (TLC's) used to map temperatures on heat pipes and thermosyphons. Color of thermally sensitive TLC coat changes reversibly upon heating or cooling. Each distinct color indicates particular temperature. Transient and steady-state isotherms become visible as colored bands. Positions and movements of bands yield information about startup transients, steady-state operation, cooler regions containing noncondensible gas, and other phenomena relevant to performance of heat pipe.
Gravity is known to influence the mechanical behavior of the lung and chest wall. However, the effect of sustained microgravity (microgravity) on lung volumes has not been reported. Pulmonary function tests were performed by four subjects before, during, and after 9 days of microgravity exposure. Ground measurements were made in standing and supine postures. Tests were performed using a bag-in-box-and-flowmeter system and a respiratory mass spectrometer. Measurements included functional residual capacity (FRC), expiratory reserve volume (ERV), residual volume (RV), inspiratory and expiratory vital capacities (IVC and EVC), and tidal volume (V9sub T)). Total lung capacity (TLC) was derived from the measured EVC and RV values. With preflight standing values as a comparison, FRC was significantly reduced by 15% (approximately 500 ml) in microgravity and 32% in the supine posture. ERV was reduced by 10 - 20% in microgravity and decreased by 64% in the supine posture. RV was significantly reduced by 18% (310 ml) in microgravity but did not significantly change in the supine posture compared with standing. IVC and EVC were slightly reduced during the first 24 h of microgravity but returned to 1-G standing values within 72 h of microgravity exposure. IVC and EVC in the supine posture were significantly reduced by 12% compared with standing. During microgravity, V(sub T) decreased by 15% (approximately 90 ml), but supine V(sub T) was unchanged compared with preflight standing values. TLC decreased by approximately 8% during microgravity and in the supine posture compared with preflight standing. The reductions in FRC, ERV, and RV during microgravity are probably due to the cranial shift of the diaphragm, an increase in intrathoracic blood volume, and more uniform alveolar expansion.
Flight control of small crew return vehicles during atmospheric reentry will be an important technology in any human space flight mission undertaken in the future. The control system presented in this paper is applicable to small crew return vehicles in which reaction control system (RCS) thrusters are the only actuators available for attitude control. The control system consists of two modules: (i) the attitude controller using the trajectory linearization control (TLC) technique, and (ii) the reaction control system (RCS) control allocation module using a dynamic table-lookup technique. This paper describes the design and implementation of the TLC attitude control and the dynamic table-lookup RCS control allocation for nonimal flight along with design verification test results.
Maneuver reconstructions for the Gravity Recovery and Interior Laboratory (GRAIL) A and B lunar orbiters were improved through updates to the orbit determination filter and dynamic models. Consistent reconstructions of the 27 GRAIL A and B maneuvers from the Trans-Lunar Cruise phase in the fall of 2011 through the Transition to Science Formation phase in February 2012 were performed. Standard methods of orbit determination were applied incorporating the latest dynamic models and filter strategies developed by the GRAIL Navigation and Science Teams, including a high resolution, 420 x 420 degree and order lunar spherical harmonic gravity field model. For Trans-Lunar Cruise for GRAIL-A (TLC-A), all maneuvers executed with delta V errors below 5.50 +/- 0.50 mm/s and pointing errors below 0.25 degrees. GRAIL-A lunar orbit maneuvers had delta V errors below 30.0 mm/s and pointing errors below 0.51 degrees. For TLC-B, all maneuvers executed with delta V errors below 8.60 +/- 1.41 mm/s and pointing errors below 0.300 degrees. GRAIL-B maneuvers in lunar orbit executed with maximum delta V errors of 25.0 mm/s and pointing error of 0.43 degrees. These maneuver reconstructions will enable the GRAIL Navigation Team to better characterize the main engine performance of each spacecraft. This will help the Navigation Team to navigate low (greater than 8 km) altitude orbits during the extended mission phase in the fall of 2012.
Physical vapor deposition (PVD) provides a route to prepare highly stable and anisotropic organic glasses that are utilized in multi-layer structures such as organic light-emitting devices. While previous work has demonstrated that anisotropic glasses with uniaxial symmetry can be prepared by PVD, here, we prepare biaxially aligned glasses in which molecular orientation has a preferred in-plane direction. With the collective effect of the surface equilibration mechanism and template growth on an aligned substrate, macroscopic biaxial alignment is achieved in depositions as much as 180 K below the clearing point TLC−iso (and 50 K below the glass transition temperature Tg) with single-component disk-like (phenanthroperylene ester) and rod-like (itraconazole) mesogens. The preparation of biaxially aligned organic semiconductors adds a new dimension of structural control for vapor-deposited glasses and may enable polarized emission and in-plane control of charge mobility.
Single-event upset (SEU) cross sections are reduced in 176-layer charge trap (CT) 3-D nand devices under proton irradiation when multiple write operations are applied sequentially without the typical erase-before-write. Here, this effect is observed for multiple data patterns and in both single-level cell (SLC) and triple-level cell (TLC) operating modes. SEU cross section calculation methodologies are discussed for highly scaled 3-D devices both with and without the application of rewrites, and potential implications for long-term endurance effects are proposed.