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Results for “NASA Discipline Number 99-99”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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17 records
All sourcesNASA NTRSDOE OSTI
NASA NTRS1996

The Neurolab mission and biomedical engineering: a partnership for the future

Over the last five years, with the advent of flights of U.S. Shuttle/Spacelab missions dedicated entirely to life sciences research, the opportunities for conducting serious studies that use a fully outfitted space laboratory to better understand basic biological processes have increased. The last of this series of Shuttle/Spacelab missions, currently scheduled for 1998, is dedicated entirely to neuroscience and behavioral research. The mission, named Neurolab, includes a broad range of experiments that build on previous research efforts, as well as studies related to less mature areas of space neuroscience. The Neurolab mission provides the global scientific community with the opportunity to use the space environment for investigations that exploit microgravity to increase our understanding of basic processes in neuroscience. The results from this premier mission should lead to a significant advancement in the field as a whole and to the opening of new lines of investigation for future research. Experiments under development for this mission will utilize human subjects as well as a variety of other species. The capacity to carry out detailed experiments on both human and animal subjects in space allows a diverse complement of studies that investigate functional changes and their underlying molecular, cellular, and physiological mechanisms. In order to conduct these experiments, a wide array of biomedical instrumentation will be used, including some instruments and devices being developed especially for the mission.

NASA Program Flight↗
NASA NTRS1996

A consensus approach to planetary protection requirements: recommendations for Mars lander missions

Over the last several years, the nature of the surface conditions on the planet Mars, our knowledge of the growth capabilities of Earth organisms under extreme conditions, and future opportunities for Mars exploration have been under extensive review in the United States and elsewhere. As part of these examinations, in 1992 the US Space Studies Board made a series of recommendations to NASA on the requirements that should be implemented on future missions that will explore Mars. In particular, significant changes were recommended in the requirements for Mars landers, changes that significantly alleviated the burden of planetary protection implementation for these missions. In this paper we propose a resolution implementing this new set of recommendations, for adoption by COSPAR at its 30th meeting in Hamburg. We also discuss future directions and study areas for planetary protection, in light of changing plans for Mars exploration.

NASA Discipline Number 99-99↗
NASA NTRS1994

Introduction: an overview of gravity sensing, perception, and signal transduction in animals and plants

The antiquity of biological sensitivity and response to gravity can be traced through the ubiquity of morphology, mechanisms, and cellular events in gravity sensing biological systems in the most diverse species of both plants and animals. Further, when we examine organisms at the cellular level to elucidate the molecular mechanism by which a gravitational signal is transduced into a biochemical response, the distinction between plants and animals becomes blurred.

NASA Center HQS↗
NASA NTRS1996

The fragmentation of 510 MeV/nucleon iron-56 in polyethylene. I. Fragment fluence spectra

The fragmentation of 510 MeV/nucleon iron ions in several thicknesses of polyethylene has been measured. Non-interacting primary beam particles and fragments have been identified and their LETs calculated by measuring ionization energy loss in a stack of silicon detectors. Fluences, normalized to the incident beam intensity and corrected for detector effects, are presented for each fragment charge and target. Histograms of fluence as a function of LET are also presented. Some implications of these data for measurements of the biological effects of heavy ions are discussed.

NASA Center HQS↗
NASA NTRS1990

Chemical evolution and the origin of life: cumulative keyword subject index 1970-1986

This cumulative subject index encompasses the subject indexes of the bibliographies on Chemical Evolution and the Origin of Life that were first published in 1970 and have continued through publication of the 1986 bibliography supplement. Early bibliographies focused on experimental and theoretical material dealing directly with the concepts of chemical evolution and the origin of life, excluding the broader areas of exobiology, biological evolution, and geochemistry. In recent years, these broader subject areas have also been incorporated as they appear in literature searches relating to chemical evolution and the origin of life, although direct attempts have not been made to compile all of the citations in these broad areas. The keyword subject indexes have also undergone an analogous change in scope. Compilers of earlier bibliographies used the most specific term available in producing the subject index. Compilers of recent bibliographies have used a number of broad terms relating to the overall subject content of each citation and specific terms where appropriate. The subject indexes of these 17 bibliographies have, in general, been cumulatively compiled exactly as they originally appeared. However, some changes have been made in an attempt to correct errors, combine terms, and provide more meaningful terms.

NASA Center HQS↗
NASA NTRS1990

Medical considerations for extending human presence in space

The prospects for extending the length of time that humans can safely remain in space depend partly on resolution of a number of medical issues. Physiologic effects of weightlessness that may affect health during flight include loss of body fluid, functional alterations in the cardiovascular system, loss of red blood cells and bone mineral, compromised immune system function, and neurosensory disturbances. Some of the physiologic adaptations to weightlessness contribute to difficulties with readaptation to Earth's gravity. These include cardiovascular deconditioning and loss of body fluids and electrolytes; red blood cell mass; muscle mass, strength, and endurance; and bone mineral. Potentially harmful factors in space flight that are not related to weightlessness include radiation, altered circadian rhythms and rest/work cycles, and the closed, isolated environment of the spacecraft. There is no evidence that space flight has long-term effects on humans, except that bone mass lost during flight may not be replaced, and radiation damage is cumulative. However, the number of people who have spent several months or longer in space is still small. Only carefully-planned experiments in space preceded by thorough ground-based studies can provide the information needed to increase the amount of time humans can safely spend in space.

Review, Tutorial↗
NASA NTRS1996

Space research activities during missions of the past

For over 30 yr, men and women have lived for various periods of time in a weightless (or free-fall) environment while orbiting the Earth. During these years, we have learned that humans function quite well for short periods of weightlessness, that is, for up to a little more than a year. Some space flight missions have provided physiologic data, including cardiovascular data, from the spacefarers. In fact, some missions have provided laboratories for systematic study of cardiovascular responses and adaptation to space flight. However, the opportunity to obtain physiologic data from people in space is a rarity. It is important to remember that the population sample sizes are small, other stresses may confound the effects of weightlessness, and in some situations the crewmembers are subjects for several experiments at the same time. Furthermore, comparison of cardiovascular data from space flight to data obtained on the ground is sometimes difficult because the subject's posture on the ground is not always reported; in a gravity environment, posture influences the hydrostatic gradient. This over view describes what we have learned about cardiovascular function during flight and after return to Earth.

NASA Discipline Cardiopulmonary↗
NASA NTRS1993

Space Station Freedom: a unique laboratory for gravitational biology research

The advent of Space Station Freedom (SSF) will provide a permanent laboratory in space with unparalleled opportunities to perform biological research. As with any spacecraft there will also be limitations. It is our intent to describe this space laboratory and present a picture of how scientists will conduct research in this unique environment we call space. SSF is an international venture which will continue to serve as a model for other peaceful international efforts. It is hoped that as the human race moves out from this planet back to the moon and then on to Mars that SSF can serve as a successful example of how things can and should be done.

NASA Program Life Sciences Management↗
NASA NTRS1988

Assessment of the efficacy of medical countermeasures in space flight

Changes in body fluids, electrolytes, and muscle mass are manifestations of adaptation to space flight and readaptation to the 1-g environment. The purposes of this paper are to review the current knowledge of biomedical responses to short- and long-duration space missions and to assess the efficacy of countermeasures to 1-g conditioning. Exercise protocols, fluid hydration, dietary and potential pharmacologic measures are evaluated, and directions for future research activities are recommended.

NASA Discipline General Space Life Sciences↗
NASA NTRS1996

The fragmentation of 510 MeV/nucleon iron-56 in polyethylene. II. Comparisons between data and a model

The results of a Monte Carlo model for calculating fragment fluences and LET spectra are compared to data taken with 600 MeV/nucleon iron ions incident on an accelerator beamline configured for irradiation of biological samples, with no target and with 2, 5 and 8 cm of polyethylene. The model uses a multi-generation nuclear fragmentation code, coupled with a formulation of ionization energy loss based on the Bethe-Bloch equation. In the region where the data are reliable and the experimental acceptance is well understood, many of the features of the experimental spectra are well replicated by the model. To obtain good agreement with the experimental data, the model must allow for at least two generations of fragment production in the target.

NASA Discipline Number 99-99↗
NASA NTRS1984

Experiments on plants grown in space. Status and prospects

Space flight provides a unique capability to gravitational research by providing an environment in which gravity can be manipulated below the Earth norm of 1 to a state comparable to weightlessness. Although space experiments with seeds and plants have been conducted for almost 25 years, we are only now entering an era that promises the capability of routinely conducting controlled plant experiments in space. Results from experiments with higher plants and seeds flown thus far in both manned and unmanned spacecraft from both the USA and USSR are briefly summarized. An overview of the current status of space biology experimentation as it relates to plants is presented and present and future opportunities to conduct plant experiments under space flight conditions are discussed.

Flight Experiment↗
NASA NTRS1987

Plants in space

Space may be, as some have called it, our last frontier. As such, it provides novel, even unique research opportunities. Plants are sure to figure significantly in these activities. The ability to manipulate the force of gravity from near zero to 1 g affords fresh opportunities to investigate gravity's physiological effects as well as a means of probing gravi- and phototropism, thigmo-morphogenesis, and other environmental effects in a state uncompromised by gravity. In this review we aim primarily to consider phenomenology, a goal that befits the state of our knowledge from space experiments. We intend to provide grist for future ground-based and space experiments and to reveal the potential for scientific discovery in this area.

long duration↗
NASA NTRS1996

Life sciences space missions. Overview

It has been known for many years that weightlessness induces changes in numerous physiological systems: the cardiovascular system declines in both aerobic capacity and orthostatic tolerance; there is a reduction in fluid and electrolyte balance, hematocrit, and certain immune parameters; bone and muscle mass and strength are reduced; various neurological responses include space motion sickness and posture and gate alterations. These responses are caused by the hypokinesia of weightlessness, the cephalic fluid shift, the unloading of the vestibular system, stress, and the altered temporal environment.

NASA Center HQS↗