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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 19 records

Immediate effects of acute Mars mission equivalent doses of SEP and GCR radiation on the murine gastrointestinal system-protective effects of curcumin-loaded nanolipoprotein particles (cNLPs)

Introduction: Missions beyond low Earth orbit (LEO) will expose astronauts to ionizing radiation (IR) in the form of solar energetic particles (SEP) and galactic cosmic rays (GCR) including high atomic number and energy (HZE) nuclei. The gastrointestinal (GI) system is documented to be highly radiosensitive with even relatively low dose IR exposures capable of inducing mucosal lesions and disrupting epithelial barrier function. IR is also an established risk factor for colorectal cancer (CRC) with several studies examining long-term GI effects of SEP/GCR exposure using tumor-prone APC mouse models. Studies of acute short-term effects of modeled space radiation exposures in wildtype mouse models are more limited and necessary to better define charged particle- induced GI pathologies and test novel medical countermeasures (MCMs) to promote astronaut safety. Methods: In this study, we performed ground-based studies where male and female C57BL/6J mice were exposed to γ-rays, 50 MeV protons, or 1 GeV/n Fe-56 ions at the NASA Space Radiation Laboratory (NSRL) with histology and immunohistochemistry endpoints measured in the first 24 h post-irradiation to define immediate SEP/GCR-induced GI alterations. Results: Our data show that unlike matched γ-ray controls, acute exposures to protons and iron ions disrupts intestinal function and induces mucosal lesions, vascular congestion, epithelial barrier breakdown, and marked enlargement of mucosa-associated lymphoid tissue. We also measured kinetics of DNA double-strand break (DSB) repair using gamma-H2AX- specific antibodies and apoptosis via TUNEL labeling, noting the induction and disappearance of extranuclear cytoplasmic DNA marked by gamma-H2AX only in the charged particle-irradiated samples. We show that 18 h pre-treatment with curcumin-loaded nanolipoprotein particles (cNLPs) delivered via IV injection reduces DSB-associated foci levels and apoptosis and restore crypt villi lengths. Discussion: These data improve our understanding of physiological alterations in the GI tract immediately following exposures to modeled space radiations and demonstrates effectiveness of a promising space radiation MCM.

59 BASIC BIOLOGICAL SCIENCES↗

Exploring Gamma-Ray and Neutron Spectroscopy Missions to Mars Caves [Slides]

In this work, we investigate the sensitivity of active neutron detector systems in Mars caves using MCNP6 to model neutron transport in different cave geometries, compositions, and detectors to determine if active neutron measurements can be used to identify the hydration of cave walls vs floor vs ceilings, and to perform a concept study for potential future Mars cave missions in search of hydration and habitable regions.

79 ASTRONOMY AND ASTROPHYSICS↗

Demonstrating autonomous controls on hardware test beds is a necessity for successful missions to Mars and beyond

NASA and the Department of Defense are planning for a mission to Mars in the 2030s–2040s using nuclear thermal propulsion (NTP). NTP uses a nuclear reactor to heat flowing hydrogen and create thrust. A serious concern for crewed and uncrewed missions to Mars is the loss of reactor control. The reactor startup and initial rocket impulse are initiated in cislunar or near-earth orbital regions; therefore, radio communications between ground control and the NTP engine should occur in real time. However, radio communications can take more than 20 min, depending on planet positions, to reach Mars orbiters from ground control. To address this delay, local autonomous controls are implemented onboard the NTP engine to ensure acceptable operation. However, autonomous controls have not been demonstrated or implemented in research or power reactor contexts because of safety and reliability concerns. To enable autonomous controls development, demonstration, and validation, Oak Ridge National Laboratory has created a nonnuclear hardware-in-the-loop test bed. Sensors throughout the test bed relay system status and hardware response to the user control algorithm, including measurements of temperature, flow, pressure of a loop, control drum position, and drum speed. This paper discusses the development of this facility and user accessibility.

33 ADVANCED PROPULSION SYSTEMS↗

Assessment of Wind Energy Resource Potential for Future Human Missions to Mars

Energy sustainability and redundancy for surface habitats, life support systems and scientific instrumentation represent one of the highest-priority issues for future crewed missions to Mars. However, power sources utilized for the current class of robotic missions to Mars may be potentially dangerous near human surface habitats (for example, nuclear) or lack stability on diurnal or seasonal timescales (for example, solar) that cannot be easily compensated for by power storage. Here, we evaluate the power potential for wind turbines as an alternative energy resource on the Mars surface. Using a state-of-the-art Mars global climate model, we analyse the total planetary Martian wind potential and calculate its spatial and temporal variability. We find that wind speeds at some proposed landing sites are sufficiently fast to provide a stand-alone or complementary energy source to solar or nuclear power. While several regions show promising wind energy resource potential, other regions of scientific interest can be discarded based on the natural solar and wind energy potential alone. We demonstrate that wind energy compensates for diurnal and seasonal reductions in solar power particularly in regions of scientific merit in the midlatitudes and during regional dust storms. Critically, proposed turbines stabilize power production when combined with solar arrays, increasing the percent time that power exceeds estimated mission requirements from ~40% for solar arrays alone to greater than 60-90% across a broad fraction of the Mars surface. We encourage additional study aimed at advancing wind turbine technology to operate efficiently under Mars conditions and to extract more power from Mars winds.

atmospheric dynamics↗

Application of multi-method-multi-model inference to radiation related solid cancer excess risks models for astronaut risk assessment

The impact of including model-averaged excess radiation risks (ER) into a measure of radiation attributed decrease of survival (RADS) for the outcome all solid cancer incidence and the impact on the uncertainties is demonstrated. It is shown that RADS applying weighted model averaged ER based on AIC weights result in smaller risk estimates with narrower 95% CI than RADS using ER based on BIC weights. Further a multi-method-multi-model inference approach is introduced that allows calculating one general RADS estimate providing a weighted average risk estimate for a lunar and a Mars mission. For males the general RADS estimate is found to be 0.42% (95% CI: 0.38%; 0.45%) and for females 0.67% (95% CI: 0.59%; 0.75%) for a lunar mission and 2.45% (95% CI: 2.23%; 2.67%) for males and 3.91% (95% CI: 3.44%; 4.39%) for females for a Mars mission considering an age at exposure of 40 years and an attained age of 65 years. It is recommended to include these types of uncertainties and to include model-averaged excess risks in astronaut risk assessment.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Nuclear Thermal Rocket Emulator for a Hardware-in-the-Loop Test Bed

To support NASA’s mission to use nuclear thermal rockets for future Mars missions, an instrumentation and control test bed has been built at Oak Ridge National Laboratory. The system is designed as a hardware-in-the-loop test bed for testing control elements and autonomous control algorithms for nuclear thermal propulsion rockets. The mock reactor system consists of a modular and scalable framework, using inexpensive components and open-source software. The hardware system consists of a two-phase flow loop and a mock reactor with six control drums. A single-board computer (NVIDIA Jetson) handles reactor core emulation and hosts a message queuing telemetry transport broker that allows user-deployed control algorithms to interact with the system hardware. The reactor emulator receives sensor data from the hardware and provides the simulated performance of the reactor under steady-state, transient, and fault conditions. The emulator uses a reactivity lookup table and the point kinetics equations to solve for the reactor dynamics in real time. Emulated reactor dynamics and sensor input inform the autonomous control algorithm’s decision-making in a closed-loop manner. The current system is capable of operating at 10 Hz, but faster cycle rates are an area of ongoing research. This test bed will enable NASA and other space vendors to rigorously test their autonomous control systems for NTP rockets under transient (reactor startup and shutdown), steady-state, and fault conditions to reduce development time and risk for autonomous control systems in future missions.

autonomous control↗

Modelling Nuclear Thermal Propulsion Reactor Startup Transients

The National Aeronautics and Space Administration (NASA) has set the goal of a manned mission to Mars by the year 2030 [1] and charged the national academy of sci- ences "to identify primary technical and programmatic chal- lenges, merits, and risks for maturing space nuclear propulsion technologies of interest to a future human Mars exploration mission" [2]. One relevant technology, nuclear thermal propul- sion (NTP), has notable advantages over traditional chemical rockets; most important among them is the ability to produce larger specific impulse on the order of 900s. The reduction of mission time is crucial for a manned mission to Mars to reduce the risk for the crew. Due to its higher specific impulse, NTP satisfies this need and is pursued as one technology to get humans to Mars [3, 4]. The construction of an NTP sys- tem has to negotiate several challenges laid out in Ref. [2]; one of these challenges is the need to startup the NTP sys- tem from essentially cold conditions to full power within one minute. This paper focuses on studying the neutronics and thermal-hydraulics behavior of a simplified NTP model dur- ing prescribed reactivity insertions and mass flow rate (MFR) ramps. It is the goal of this paper to investigate startup, peak material temperatures, and average specific impulse for a low enriched Uranium (LEU), ceramic and metal material (CER- MET) NTP system when varying reactivity insertion and MFR ramps.

33 ADVANCED PROPULSION SYSTEMS↗

Description and Genome Characterization of Three Novel Fungal Strains Isolated from Mars 2020 Mission-Associated Spacecraft Assembly Facility Surfaces—Recommendations for Two New Genera and One Species

National Aeronautics and Space Administration’s (NASA) spacecraft assembly facilities are monitored for the presence of any bacteria or fungi that might conceivably survive a transfer to an extraterrestrial environment. Fungi present a broad and diverse range of phenotypic and functional traits to adapt to extreme conditions, hence the detection of fungi and subsequent eradication of them are needed to prevent forward contamination for future NASA missions. During the construction and assembly for the Mars 2020 mission, three fungal strains with unique morphological and phylogenetic properties were isolated from spacecraft assembly facilities. The reconstruction of phylogenetic trees based on several gene loci (ITS, LSU, SSU, RPB, TUB, TEF1) using multi-locus sequence typing (MLST) and whole genome sequencing (WGS) analyses supported the hypothesis that these were novel species. Here we report the genus or species-level classification of these three novel strains via a polyphasic approach using phylogenetic analysis, colony and cell morphology, and comparative analysis of WGS. The strain FJI-L9-BK-P1 isolated from the Jet Propulsion Laboratory Spacecraft Assembly Facility (JPL-SAF) exhibited a putative phylogenetic relationship with the strain Aaosphaeria arxii CBS175.79 but showed distinct morphology and microscopic features. Another JPL-SAF strain, FJII-L3-CM-DR1, was phylogenetically distinct from members of the family Trichomeriaceae and exhibited morphologically different features from the genera Lithohypha and Strelitziana. The strain FKI-L1-BK-DR1 isolated from the Kennedy Space Center facility was identified as a member of Dothideomycetes incertae sedis and is closely related to the family Kirschsteiniotheliaceae according to a phylogenetic analysis. The polyphasic taxonomic approach supported the recommendation for establishing two novel genera and one novel species. The names Aaosphaeria pasadenensis (FJI-L9-BK-P1 = NRRL 64424 = DSM 114621), Pasadenomyces melaninifex (FJII-L3-CM-DR1 = NRRL 64433 = DSM 114623), and Floridaphiala radiotolerans (FKI-L1-BK-DR1 = NRRL 64434 = DSM 114624) are proposed as type species. Furthermore, resistance to ultraviolet-C and presence of specific biosynthetic gene cluster(s) coding for metabolically active compounds are unique to these strains.

59 BASIC BIOLOGICAL SCIENCES↗

Quantitative modeling of carcinogenesis induced by single beams or mixtures of space radiations using targeted and non-targeted effects

Abstract Ionizing radiations encountered by astronauts on deep space missions produce biological damage by two main mechanisms: (1) Targeted effects (TE) due to direct traversals of cells by ionizing tracks. (2) Non-targeted effects (NTE) caused by release of signals from directly hit cells. The combination of these mechanisms generates non-linear dose response shapes, which need to be modeled quantitatively to predict health risks from space exploration. Here we used a TE + NTE model to analyze data on APC (1638N/+) mouse tumorigenesis induced by space-relevant doses of protons, 4 He, 12 C, 16 O, 28 Si or 56 Fe ions, or γ rays. A customized weighted Negative Binomial distribution was used to describe the radiation type- and dose-dependent data variability. This approach allowed detailed quantification of dose–response shapes, NTE- and TE-related model parameters, and radiation quality metrics (relative biological effectiveness, RBE, and radiation effects ratio, RER, relative to γ rays) for each radiation type. Based on the modeled responses for each radiation type, we predicted the tumor yield for a Mars-mission-relevant mixture of these radiations, using the recently-developed incremental effect additivity (IEA) synergy theory. The proposed modeling approach can enhance current knowledge about quantification of space radiation quality effects, dose response shapes, and ultimately the health risks for astronauts.

60 APPLIED LIFE SCIENCES↗

External perturbation-driven Sabatier breakthrough

The Sabatier reaction (CO 2 + 4H 2 → CH 4 + 2H 2 O) is gaining renewed interest due to its potential to reduce energy carrier storage costs, serve as a feedstock for various organic chemicals, and supply in-situ propellant and life-support resources for long-duration Mars missions. This study demonstrates that combining a modest 2 mA electric field with H 2 feed modulation markedly elevates the CO 2 hydrogenation activity of 2 wt% Ru/CeO 2 catalyst. CO 2 conversion reaches 88 % and 93 % with a CH 4 yield of 83 % and 89 % at 350 °C and 450 °C, respectively. A simple lumped kinetic model reveals that the combined external perturbations not only shift the reaction mechanism but also redistribute key surface-adsorbed intermediates such as hydrogen adatoms and hydrogen-activated CO 2 among the Ru clusters, Ru/CeO 2 interface, and ceria surface. The electric field accelerates the conversion of adsorbed CO 2 to the hydrogenated CO 2 species on Ru and boosts CH 4 formation rate constant, while simultaneously suppresses the formation of undesired, non-reactive surface intermediates. Degree-of-rate-control analysis pinpoints proton migration across the metal-support interface as the decisive lever under these coupled perturbations. In conclusion, these findings establish that rational pairing of metal-support design with well-tuned electric fields and feed oscillations can unlock unprecedented Sabatier rates, guiding the development of next-generation reactors for efficient CO 2 to CH 4 conversion.

10 - SYNTHETIC FUELS↗

Development and verification of the pyIsoDep depletion package for nuclear thermal propulsion reactors

Nuclear thermal propulsion technology is currently being developed by the National Air and Space Administration for future manned Mars missions. There are multiple on-going activities to develop and enhance computational capabilities, single- and multi-physics, to advance the readiness level of this technology. The prediction of short-lived fission products is crucial to understand the reactivity penalty and the decay heat production during the different burnout stages of the vehicle. Generally, the solution entails coupled neutronic-depletion analysis. However, such simulations are somewhat expensive, especially if the duration of each engine burn is to be optimized. Therefore, there is a need to complement such high-fidelity techniques with time-efficient alternatives that do not require the sequential neutronic and depletion analysis. This paper details the methods and capabilities of pyIsoDep, an open-source code used for depletion analysis of nuclear thermal propulsion reactors. The package is general, in principle, and thus can be applied to any fission system, and can potentially be extended for fusion systems. The package was developed to provide a flexible and efficient alternative to pre-existing higher order depletion codes that could integrate well into mission and transient analysis of nuclear thermal propulsion reactors. Finally, this paper presents a validation and verification of pyIsoDep against analytical and Serpent-generated solutions. (authors)

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗

Search for Infrasound Signals in InSight Data Using Coupled Pressure/Ground Deformation Methods

The unprecedented quality and sampling rate of seismometer and pressure sensors of the InSight Mars mission allow us to investigate infrasound through its pressure and ground deformation signals. This study focuses on compliance effects induced by acoustic waves propagating almost horizontally close to the surface. The compliance of acoustic waves is first estimated using the compliance estimates from pressure perturbations moving at wind speed. Then, a marker of compliance events is used to detect events of ground deformation induced by pressure variations, in three frequency bands from 0.4 to 3.2 Hz, from InSight sol 180 to 690. Additional selection criteria are imposed on the detected events to focus on acoustic waves and to remove various noise sources (e.g., wind effects or seismometer artifacts). After an automated selection, the visual inspection of the records allows us to validate two infrasound candidates that cannot be related to pressure perturbations moving at wind speed nor to known noise sources. For our highest quality infrasound candidate, the relation between this event and a convective vortex occuring 10 s later is tested. The azimuth of the vortex position at the time of infrasound detection is not consistent with the arrival azimuth of the suspected infrasound inferred from the polarization of seismometer records, thus the link between these two phenomena cannot be demonstrated. Further investigations would require a better understanding of wind-related noise impacting InSight sensors and of the effects of lateral variations of subsurface mechanical properties on the ground deformations induced by atmospheric pressure variations.

58 GEOSCIENCES↗

Dynamic Electric Field Assisted CO 2 Methanation

Energy-efficient advanced chemical reactions are essential for accelerating the growth of hydrocarbon economy. Sabatier reaction stands out for its potential to effectively transform carbon dioxide into valuable hydrocarbons and is an asset for long-duration Mars missions. This study explores a novel catalytic approach that harnesses electric field-assisted catalysis to substantially enhance the efficiency of the Sabatier reaction. Application of a dynamically perturbed electric field at 1000 Hz resulted in remarkable enhancements, increasing methane formation rates by over 100% at 350 °C and by 74% at 400 °C. Post-reaction catalyst characterization further revealed reduced blockage of active catalytic surface area under the applied electric field, emphasizing improved catalytic longevity and sustained activity. These results underscore the potential of tailored electric field waveforms to dynamically modulate elementary reaction kinetics and surface processes, positioning electric field-assisted catalysis as a transformative strategy for energy-efficient, cost-effective chemical manufacturing and energy conversion technologies.

42 - ENGINEERING↗

A bespoke health risk assessment methodology for the radiation protection of astronauts

An alternative approach that is particularly suitable for the radiation health risk assessment (HRA) of astronauts is presented. The quantity, Radiation Attributed Decrease of Survival (RADS), representing the cumulative decrease in the unknown survival curve at a certain attained age, due to the radiation exposure at an earlier age, forms the basis for this alternative approach. Results are provided for all solid cancer plus leukemia incidence RADS from estimated doses from theoretical radiation exposures accumulated during long-term missions to the Moon or Mars. For example, it is shown that a 1000-day Mars exploration mission with a hypothetical mission effective dose of 1.07 Sv at typical astronaut ages around 40 years old, will result in the probability of surviving free of all types of solid cancer and leukemia until retirement age (65 years) being reduced by 4.2% (95% CI 3.2; 5.3) for males and 5.8% (95% CI 4.8; 7.0) for females. RADS dose–responses are given, for the outcomes for incidence of all solid cancer, leukemia, lung and female breast cancer. Results showing how RADS varies with age at exposure, attained age and other factors are also presented. The advantages of this alternative approach, over currently applied methodologies for the long-term radiation protection of astronauts after mission exposures, are presented with example calculations applicable to European astronaut occupational HRA. Some tentative suggestions for new types of occupational risk limits for space missions are given while acknowledging that the setting of astronaut radiation-related risk limits will ultimately be decided by the Space Agencies. Suggestions are provided for further work which builds on and extends this new HRA approach, e.g., by eventually including non-cancer effects and detailed space dosimetry.

61 RADIATION PROTECTION AND DOSIMETRY↗