Mutation of the conserved Asp-Asp pair impairs the structure, function, and inhibition of CTX-M Clas
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Kemp, M. Trent↗
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Determination of ASPS performance for large payloads in the shuttle orbiter disturbance environment
A high fidelity simulation of the annular suspension and pointing system (ASPS), its payload, and the shuttle orbiter was used to define the worst case orientations of the ASPS and its payload for the various vehicle disturbances, and to determine the performance capability of the ASPS under these conditions. The most demanding and largest proposed payload, the Solar Optical Telescope was selected for study. It was found that, in all cases, the ASPS more than satisfied the payload's requirements. It is concluded that, to satisfy facility class payload requirements, the ASPS or a shuttle orbiter free-drift mode (control system off) should be utilized.
Keckler, C. R.↗
Array Simulations Platform (ASP) predicts NASA Data Link Module (NDLM) performance
Through a variety of imbedded theoretical and actual antenna patterns, the array simulation platform (ASP) enhanced analysis of the array antenna pattern effects for the KTx (Ku-Band Transmit) service of the NDLM (NASA Data Link Module). The ASP utilizes internally stored models of the NDLM antennas and can develop the overall pattern of antenna arrays through common array calculation techniques. ASP expertly assisted in the diagnosing of element phase shifter errors during KTx testing and was able to accurately predict the overall array pattern from combinations of the four internally held element patterns. This paper provides an overview of the use of the ASP software in the solving of array mis-phasing problems.
Snook, Allen David↗
Laboratory evaluation of the pointing stability of the ASPS Vernier System
The annular suspension and pointing system (ASPS) is an end-mount experiment pointing system designed for use in the space shuttle. The results of the ASPS Vernier System (AVS) pointing stability tests conducted in a laboratory environment are documented. A simulated zero-G suspension was used to support the test payload in the laboratory. The AVS and the suspension were modelled and incorporated into a simulation of the laboratory test. Error sources were identified and pointing stability sensitivities were determined via simulation. Statistical predictions of laboratory test performance were derived and compared to actual laboratory test results. The predicted mean pointing stability during simulated shuttle disturbances was 1.22 arc seconds; the actual mean laboratory test pointing stability was 1.36 arc seconds. The successful prediction of laboratory test results provides increased confidence in the analytical understanding of the AVS magnetic bearing technology and allows confident prediction of in-flight performance. Computer simulations of ASPS, operating in the shuttle disturbance environment, predict in-flight pointing stability errors less than 0.01 arc seconds.
Source record↗
AmeriFlux FLUXNET-1F US-Mo1 LTAR CMRB Field 1 (CMRB ASP)
This is the AmeriFlux Management Project (AMP) created FLUXNET-1F version of the carbon flux data for the site US-Mo1 LTAR CMRB Field 1 (CMRB ASP). This is the FLUXNET version of the carbon flux data for the site US-Mo1 LTAR CMRB Field 1 (CMRB ASP) produced by applying the standard ONEFlux (1F) software. Site Description - Site is in a 36 ha agricultural research field near Centralia, MO on a broad, slightly sloped landscape. Currently farmed in a corn-soybean-wheat-hay rotation. Used for research since 1991; prior to that was managed for commercial crop production.
Schreiner-McGraw, Adam↗
ASPS performance with large payloads onboard the Shuttle Orbiter
A high fidelity digital computer simulation was used to establish the viability of the Annular Suspension and Pointing System (ASPS) for satisfying the pointing and stability requirements of facility class payloads, such as the Solar Optical Telescope, when subjected to the Orbiter disturbance environment. The ASPS and its payload were subjected to disturbances resulting from crew motions in the Orbiter aft flight deck and VRCS thruster firings. Worst case pointing errors of 0.005 arc seconds were experienced under the disturbance environment simulated; this is well within the 0.08 arc seconds requirement specified by the payload.
Keckler, C. R.↗
Annular Suspension and Pointing System (ASPS) magnetic rotary joint
The Annular Suspension and Pointing System (ASPS) is a prototype of flight hardware for a high-accuracy space payload pointing mount. The long term project objective is to perform modifications and implement improvements to the existing ASPS in hopes of recommission. Also, new applications will be investigated for this technology. This report will focus on the first aspect of this overall goal, to establish operation of a single bearing station. Presented is an overview of the system history and bearing operation followed by the processes, results, and status of the single bearing study.
Smith, W. E.↗
The Absolute Spectrum Polarimeter (ASP)
The Absolute Spectrum Polarimeter (ASP) is an Explorer-class mission to map the absolute intensity and linear polarization of the cosmic microwave background and diffuse astrophysical foregrounds over the full sky from 30 GHz to 5 THz. The principal science goal is the detection and characterization of linear polarization from an inflationary epoch in the early universe, with tensor-to-scalar ratio r much greater than 1O(raised to the power of { -3}) and Compton distortion y < 10 (raised to the power of{-6}). We describe the ASP instrument and mission architecture needed to detect the signature of an inflationary epoch in the early universe using only 4 semiconductor bolometers.
Kogut, A. J.↗
AmeriFlux US-Mo1 LTAR CMRB Field 1 (CMRB ASP)
This is the AmeriFlux version of the carbon flux data for the site US-Mo1 LTAR CMRB Field 1 (CMRB ASP). Site Description - Site is in a 36 ha agricultural research field near Centralia, MO on a broad, slightly sloped landscape. Currently farmed in a corn-soybean-wheat-hay rotation. Used for research since 1991; prior to that was managed for commercial crop production.
Schreiner-McGraw, Adam↗
AmeriFlux US-LMA Mississippi ARS Arant ASP
This is the AmeriFlux version of the carbon flux data for the site US-LMA Mississippi ARS Arant ASP. Site Description - Field
Witthaus, Lindsey [USDA ARS]↗
Comparison of Response Times for the Thermo ASP-2S1/NRD and Ludlum 30-7B Neutron Instruments
Health Physics Services (HPS) received feedback from a customer service survey regarding the difference in response times between the Thermo ASP-2S1/NRD (Thermo) and Ludlum Model 30-7B (Ludlum). In response to the feedback, tests were performed in the field and duplicated in a laboratory to evaluate and compare each instrument’s response time to reach an applied exposure. The results of the tests showed that optimizing its screen refresh rate by updating the Ludlum’s firmware improves response time, making it more comparable to the Thermo.
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
Nonlinear analysis and performance evaluation of the Annular Suspension and Pointing System (ASPS)
The Annular Suspension and Pointing System (ASPS) can provide high accurate fine pointing for a variety of solar-, stellar-, and Earth-viewing scientific instruments during space shuttle orbital missions. In this report, a detailed nonlinear mathematical model is developed for the ASPS/Space Shuttle system. The equations are augmented with nonlinear models of components such as magnetic actuators and gimbal torquers. Control systems and payload attitude state estimators are designed in order to obtain satisfactory pointing performance, and statistical pointing performance is predicted in the presence of measurement noise and disturbances.
Joshi, S. M.↗
Conceptual design of a noncontacting power transfer device for the ASPS Vernier system
The conceptual of electrical power transfer across a magnetically controlled gap as discussed for several years. The design represents the culmination of the first serious attempt to design a very low force, noncontracting power transfer mechanism. The electromagnetic device advanced herein is an ironless, translatable secondary transformer in which one of the two coils is fixed to the entire magnetic core. The second coil is free to move within the core over the full range of motions required. The specific application considered for this design was the Vernier subsystem of the Annular Suspension and Pointing System (ASPS). The development of and rationale for the electromagnetics design is presented. Similar documentation is provided for the Electronics Design. The Appendices detail the results of small scale model tests, disturbance force calculations, the baseline transformer fabrication drawings, the AVS Converter Parts List, and model schematic diagrams.
Kroeger, J.↗
An Arg-Gly-Asp peptide stimulates Ca2+ efflux from osteoclast precursors through a novel mechanism
We examined the effect of a peptide containing the Arg-Gly-Asp (RGD) sequence on 45Ca2+ efflux from osteoclast precursors. 45Ca(2+)-loaded osteoclast precursors were treated with GRGDSP (170 microM) for 10 min after 30 min of basal perfusion with a bicarbonate-containing buffer. GRGDSP significantly increased fractional efflux of Ca2+ from treated cells compared with vehicle-treated cells (P < 0.01) or cells treated with up to 200 micrograms/ml of a control peptide containing GRGESP. The effect of RGD was sustained for 15 min after the peptide was removed from the perfusate, but control levels of Ca2+ efflux returned by 1 h. The Ca2+ efflux effect of GRGDSP was most likely due to activation of the plasma membrane Ca(2+)-adenosinetriphosphatase (Ca(2+)-ATPase) pump, as indicated by its inhibition with vanadate and a calmodulin antagonist, N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide, and the absence of an effect of Na+/Ca2+ exchange inhibition. An inhibitor of cyclic nucleotide-dependent protein kinases, N-[2-(methylamino)ethyl]-5-isoquinoline-sulfonamide (0.1 mM), failed to inhibit GRGDSP-stimulated Ca2+ efflux. However, genistein and herbimycin A, inhibitors of protein-tyrosine kinases, blocked Ca2+ efflux stimulated by GRGDSP. The results indicate that RGD sequences of matrix proteins may stimulate Ca2+ efflux from osteoclasts through activation of protein-tyrosine kinases and suggest that GRGDSP-stimulated Ca2+ efflux is mediated via the plasma membrane Ca(2+)-ATPase.
NASA Discipline Musculoskeletal↗
AIRS Science Processing System (ASPS): a description of architecture and capabilities
This paper describes the architecture of the AIRS Science Processing System (SPS) used to process AIRS data.
AIRS ASPS SPS TLSCF TDS↗
Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2
Not provided.
Biochemistry & Molecular Biology↗
ASP (Adaptive Splines for Prediction) [SWR-22-66]
This software package provides functionality to fit piecewise cubic splines to model the relationship between a univariate X (independent variable) and a univariate Y (dependent variable). The output is akin to linear regression but has higher "capacity" in that it can learn more complicated relationships despite leveraging only a single predictor. It thus can learn very reasonable relationships between X and Y with minimal effort. The canonical intended use case is for predicting electric demand (Y) from temperature (X). There can be complicated, non-linear relationships between these two variables, but these can be reasonably approximated by the sum of: 1) an "aggregate" relationship between daily average temperature and daily average demand, and 2) intra-day patterns represented as hourly offsets from the daily average load. The spline functionality is used for learning a robust "aggregate" relationship without the inconvenience of manual feature engineering while still ensuring robust results. The model fitting workhorse is R's built-in smooth.spline. This package provides a suite of options for controlling how smooth.spline fits a spline to the data. In particular, it is designed to return a model with a single critical point (i.e., a single location along the domain/support where the first derivative is zero). This is to ensure that predicted changes in electric demand are always positive as temperatures become more extreme. This helps to prevent overfitting, particularly when the input data has few observations or has significant uncertainty from other sources.
Murphy, Sinnott↗