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At least 1,783 records · Page 99

Dst Index in the 2008 GEM Modeling Challenge - Model Performance for Moderate and Strong Magnetic Storms

The GEM 2008 modeling challenge efforts are expanding beyond comparing in-situ measurements in the magnetosphere and ionosphere to include the computation of indices to be compared. The Dst index measures the largest deviations of the horizontal magnetic field at 4 equatorial magnetometers from the quiet-time background field and is commonly used to track the strength of the magnetic disturbance of the magnetosphere during storms. Models can calculate a proxy Dst index in various ways, including using the Dessler-Parker Sckopke relation and the energy of the ring current and Biot-Savart integration of electric currents in the magnetosphere. The GEM modeling challenge investigates 4 space weather events and we compare models available at CCMC against each other and the observed values of Ost. Models used include SWMF/BATSRUS, OpenGGCM, LFM, GUMICS (3D magnetosphere MHD models), Fok-RC, CRCM, RAM-SCB (kinetic drift models of the ring current), WINDMI (magnetosphere-ionosphere electric circuit model), and predictions based on an impulse response function (IRF) model and analytic coupling functions with inputs of solar wind data. In addition to the analysis of model-observation comparisons we look at the way Dst is computed in global magnetosphere models. The default value of Dst computed by the SWMF model is for Bz the Earth's center. In addition to this, we present results obtained at different locations on the Earth's surface. We choose equatorial locations at local noon, dusk (18:00 hours), midnight and dawn (6:00 hours). The different virtual observatory locations reveal the variation around the earth-centered Dst value resulting from the distribution of electric currents in the magnetosphere during different phases of a storm.

Rastaetter, Lutz↗

Interaction of Delaminations and Matrix Cracks in a CFRP Plate, Part II: Simulation Using an Enriched Shell Finite Element Model

Numerical simulations are presented of a recently developed test which creates multiple delaminations in a CFRP laminate specimen that grow and interact via transverse matrix cracks. A novel shell element enriched with the Floating Node Method, and a damage algorithm based on the Virtual Crack Closure Technique, were used to successfully simulate the tests. Additionally, a 3D high mesh fidelity model based on cohesive zones and continuum damage mechanics was used to simulate the tests and act as a representative of other similar state-of-the-art high mesh fidelity modeling techniques to compare to the enriched shell element. The enriched shell and high mesh fidelity models had similar levels of accuracy and generally matched the experimental data. With runtimes of 36 minutes for the shell model and 55 hours for the high mesh fidelity model, the shell model is 92 times faster than the high- fidelity simulation.

Mark W McElroy↗

Creating and Using Sensors That Tell Us About Precipitation

Precipitation is deceptively simple to measure - just put a container in the back yard - and this was the only technology available until radar was discovered to be capable of sensing precipitation in the 1940's,leading to quantitative estimates by the 1970's.Meanwhile, satellite-based sensors started advancing.The first precipitation estimates from space re purposed the existing geosynchronous satellite infrared (GEO-IR) data, but purpose-built passive microwave (PMW) sensors soon became a reality. In 1987, the launch of the first Special Sensor Microwave/Imager on the Defense Meteorological Satellite Program F08 by the U.S. Department of Defense, and their decision to open the dataset top public use, created a boom in precipitation algorithms that continues to this day. Experimental work to create a global multi-satellite product by Global Precipitation Climatology Project, and then a "virtual constellation"of PMW sensors from satellite agencies around the globe by the NASA/JAXA Tropical Rainfall Measuring Mission (TRMM) and by NOAA/NWS Climate Prediction Center, resulted in a new generation of quasi-global multi-satellite precipitation estimates at increasingly fine time and space scales. TRMM and the NASA/JAXA Global Precipitation Measurement mission have hosted precipitation radars in space, providing critical new quasi-global information about 3-D precipitation structures and enabling improved calibration of the PMW constellation's estimates.

Huffman, George J.↗

AstroAmpSeq: Microbial Bioinformatics Education with NASA GeneLab’s Amplicon Pipeline

The prevalence and importance of large sequencing datasets in microbiology has led to a movement to share microbial ecology experimental data through open-access databases. This is particularly true of experiments that are difficult to replicate, such as those conducted in the spaceflight environment and shared via NASA GeneLab. It is now possible and indeed valuable for students to access and re-analyze these shared datasets for educational and research purposes. To provide students with experience utilizing microbial bioinformatics tools, GeneLab for Colleges and Universities (GL4U) has designed AstroAmpSeq, a week-long, virtually implemented project-based learning (PBL) minicourse to instruct undergraduate students on 16S amplicon sequencing. AstroAmpSeq was created to be accessible to students without prior bioinformatics or microbial ecology experience. During the minicourse students work in teams to process, analyze, and visualize a subsample of GeneLab dataset GLDS-280 using GeneLab’s standard amplicon processing pipeline, which is based in R. Students develop a hypothesis related to the dataset then generate and analyze figures to evaluate their hypothesis. Formative assessment of student learning is determined via pre- and post-evaluations, peer feedback, and self-reflection. Project and presentation rubrics serve as a summative assessment of student learning. GL4U AstroAmpSeq not only meets American Society for Microbiology Curriculum Guidelines, but also incites student interest in research by an inquiry-based approach and can be made part of a larger semester-long curriculum. GL4U AstroAmpSeq raises awareness of space microbiology and bioinformatics as a field and career path among undergraduates. Further, by using a GeneLab dataset and nesting microbiology techniques into the real-world application of space biology, AstroAmpSeq enforces deeper and longer-lasting student learning.

microbiology↗

BOREAS TE-9 In Situ Understory Spectral Reflectance Within the NSA

The Boreal Ecosystem-Atmospheric Study (BOREAS) TE-9 (Terrestrial Ecology) team collected several data sets related to chemical and photosynthetic properties of leaves in boreal forest tree species. Spectral reflection coefficients of the forest understory at the ground level, in three boreal forest sites of Northern Manitoba (56 N latitude and 98 W longitude), were obtained and analyzed in 1994. In particular, angular variation of the reflection coefficients in the old jack pine and young jack pine forests, as well as nadir reflection coefficient in the young aspen forest, were investigated. The complexity of understory composition and the light patterns limited quantitative conclusions; however, a number of interesting trends in the behavior of the measured values can be inferred. In particular, the unique spectral profiles of lichens show very strongly in the old jack pine understory, yet are definitely less conspicuous for young jack pine, and virtually absent in the aspen forest. The angular variation of the reflection coefficient by the young pine understory seems to be significantly toned down by fine-structured branches and their shadows. Our study also indicates how difficult the ground reflection coefficient problem in a forest is, compared to certain previously investigated areas that have a more uniform appearance, such as prairie grassland, bare soil, or agricultural crops. This is due to several factors, generally typical of a forest environment, that may influence the overall understory reflection coefficient, including: (1) a strong diversity of the forest floor due to the presence of dead tree trunks, holes in the ground, patches of different types of vegetation or litter, etc.; (2) pronounced 3-D structures at the ground level, such as shrubs, bushes, and young trees; and (3) an irregular shadow mosaic, which not only varies with the time of the day, causing intensity variations, but likely also effectively modifies the spectrum of the illuminating light and hence the reflection coefficient signal as well The data are stored in tabular ASCII files. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC).

Hall, Forrest G.↗

Numerical solutions for supersonic corner flow

Analytical solutions for inviscid supersonic corner flows are virtually nonexistent due to the complexity of the interference geometry. In view of this, numerical solutions for swept-compressive and swept-expansive corner flows are obtained. The governing equations are written in strong conservation-law form and are solved iteratively in nonorthogonal conical coordinates by use of a second-order, shock-capturing, finite-difference technique. The computed wave structure and surface pressure distributions are compared with high Reynolds number experimental data and show very good agreement. The results clearly show that supersonic corner flow at reasonably high Reynolds numbers including the effect of sweep is dominated by the inviscid field.

Shankar, V.↗

Resiliency of the Multiscale Retinex Image Enhancement Algorithm

The multiscale retinex with color restoration (MSRCR) continues to prove itself in extensive testing to be very versatile automatic image enhancement algorithm that simultaneously provides dynamic range compression, color constancy, and color rendition, However, issues remain with regard to the resiliency of the MSRCR to different image sources and arbitrary image manipulations which may have been applied prior to retinex processing. In this paper we define these areas of concern, provide experimental results, and, examine the effects of commonly occurring image manipulation on retinex performance. In virtually all cases the MSRCR is highly resilient to the effects of both the image source variations and commonly encountered prior image-processing. Significant artifacts are primarily observed for the case of selective color channel clipping in large dark zones in a image. These issues are of concerning the processing of digital image archives and other applications where there is neither control over the image acquisition process, nor knowledge about any processing done on th data beforehand.

Rahman, Zia-Ur↗

Integrated data-driven and experimental approaches to accelerate lead optimization targeting SARS-CoV- 2 main protease

Identification of potential therapeutic candidates can be expedited by integrating computational modeling with domain aware machine learning (ML) approaches followed by experimental validation. Generative deep learning models have been recently developed that can generate thousands of new candidates, but their physiochemical properties are typically not optimized. Using our deep learning models and a scaffold as a starting point, we generated tens of thousands of compounds for SARS-CoV-2 M pro that preserve the core scaffold. Here we utilized and implemented several computational tools such as structural alert and toxicity analysis, high throughput virtual screening, ML-based 3D quantitative structure–activity relationships, multi-parameter optimization, and graph neural networks on libraries of generated candidates to predict biological activity and binding affinity a priori. From these collective computational results, eight promising candidates were identified and tested experimentally using Native Mass Spectrometry (MS) and FRET-based functional assays. Two compounds, with quinazoline-2-thiol and acetylpiperidine core moiety showed IC 50 values in the low micromolar range: 2.95±0.0017 µM and 3.41±0.0015 µM, respectively. The molecular dynamics simulations further highlight that binding of these compounds results in allosteric modulations in the chain B and the interface domains of the M pro . The key fragments from these top hits can be used as input for closed loop lead optimization in the integrated pipeline.

60 APPLIED LIFE SCIENCES↗

Advanced Mooring Lines for Marine Energy Workshop – Summary Report

This report summarizes the outcomes of the virtual Advanced Mooring Lines for Marine Energy Workshop. The workshop convened experts from industry, academia, and national laboratories to identify key challenges associated with the deployment of synthetic mooring lines for marine energy applications. Discussions focused on four technical areas—materials, failure and degradation, testing, and modeling. Despite the significant promise of leveraging synthetic mooring systems for marine energy applications, discussion highlighted broader research and development needed to address the lack of validated long-term performance data, insufficient structural health monitoring frameworks, limited large-scale testing capabilities, and gaps in predictive modeling. Overall, the workshop emphasized the importance of coordinated research and development efforts to advance reliable, durable, and cost-effective synthetic mooring solutions for marine energy applications.

16 TIDAL AND WAVE POWER↗

Rapid Spin-Up Episodes in the Wind-Fed Accreting Pulsar GX 301-2

The accreting pulsar GX 301-2 (P = 680 s) has been observed continuously by the large-area detectors of the Burst and Transient Source Experiment (BATSE) instrument on the Compton Gamma Ray Observatory since 1991 April 5. Orbital parameters determined from these data are consistent with previous measurements, with improved accuracy in the current orbital epoch. The most striking features in the pulsar frequency history are two steady and rapid spin-up episodes, with a dot-nu approximately equal to (3_5) x 10(exp -12) Hz/s, each lasting for about 30 days. They probably represent the formation of transient accretion disks in this wind-fed pulsar. Except for these spin-up episodes, there are virtually no net changes in the neutron star spin frequency on long timescales. We suggest that the long-term spin-up trend observed since 1984 (dot-nu is approximately equals 2x10(exp -13) Hz/s) may be due entirely to brief (approximately 20 days) spin-up episodes similar to those we have discovered. We assess different accretion models and their ability to explain the orbital phase dependence of the observed flux. In addition to the previously observed preperiastron peak at orbital phase 0.956 +/- 0.022, we also find a smaller peak close to - at orbital phase 0.498 +/- 0.057. We show that if the companion star's effective temperature is less than 22,000 K, then it must have a mass M(sub c) < 70 solar mass and a radius R(sub c) < 85 solar radius so as not to overfill the tidal lobe at periastron. In order not to overflow the Roche lobe at periastron, the corresponding values are M(sub c) < 55 solar mass and R(sub c) < 68 solar radius. These constraints are nearly at odds with the reclassification of the companion as a B1 Ia + hypergiant.

Koh, Danny T.↗

A microstructural approach to cytoskeletal mechanics based on tensegrity

Mechanical properties of living cells are commonly described in terms of the laws of continuum mechanics. The purpose of this report is to consider the implications of an alternative approach that emphasizes the discrete nature of stress bearing elements in the cell and is based on the known structural properties of the cytoskeleton. We have noted previously that tensegrity architecture seems to capture essential qualitative features of cytoskeletal shape distortion in adherent cells (Ingber, 1993a; Wang et al., 1993). Here we extend those qualitative notions into a formal microstructural analysis. On the basis of that analysis we attempt to identify unifying principles that might underlie the shape stability of the cytoskeleton. For simplicity, we focus on a tensegrity structure containing six rigid struts interconnected by 24 linearly elastic cables. Cables carry initial tension ("prestress") counterbalanced by compression of struts. Two cases of interconnectedness between cables and struts are considered: one where they are connected by pin-joints, and the other where the cables run through frictionless loops at the junctions. At the molecular level, the pinned structure may represent the case in which different cytoskeletal filaments are cross-linked whereas the looped structure represents the case where they are free to slip past one another. The system is then subjected to uniaxial stretching. Using the principal of virtual work, stretching force vs. extension and structural stiffness vs. stretching force relationships are calculated for different prestresses. The stiffness is found to increase with increasing prestress and, at a given prestress, to increase approximately linearly with increasing stretching force. This behavior is consistent with observations in living endothelial cells exposed to shear stresses (Wang & Ingber, 1994). At a given prestress, the pinned structure is found to be stiffer than the looped one, a result consistent with data on mechanical behavior of isolated, cross-linked and uncross-linked actin networks (Wachsstock et al., 1993). On the basis of our analysis we concluded that architecture and the prestress of the cytoskeleton might be key features that underlie a cell's ability to regulate its shape.

NASA Discipline Cell Biology↗

Kinect Engineering with Learning (KEWL)

According to a Nielsen survey at the time of this reporting, 41% of all households have a game console. This is one market in which NASA has been absent from education and outreach efforts. Kinect Engineering with Learning (KEWL) is made to enter into that market and bring NASA education and outreach to a very familiar venue. KEWL creates an education and outreach experience that is more participatory, both in a school and museum environment. KEWL is a set of applications that runs on an Xbox 360 using the Kinect controller used for education and outreach. These applications currently include: Train R2, a visual simulation of Robonaut 2 that allows students to control a virtual R2 in a game environment; Drive R2, an interface using the Xbox 360 and Kinect controller that allows students to control the real R2 using the methods they learned playing Train R2; ISS experience, a visual tour of the interior of the International Space Station where students use their body to fly through the virtual ISS; Gravity Ball, a simulation of throwing balls in the gravity of different planets; Solar Array repair, a simulation of the simplified STS-121 solar array repair mission; and PlaySpace, a Mars/Moon application that allows students to experience different aspects of Mars/Moon. Users can "fly through" the ISS using their body, allowing an experience similar to what an astronaut would have on orbit. In PlaySpace, users can fly over the surface of Mars and view surface data obtained by Mars rovers. Users of Train R2 and Drive R2 can experience what it is like to control a robot over a distance with a time delay, simulating the time delay that would occur between ground control and an on-orbit robot. The initial ISS experiences were built using parts of code from the NASA Enigma software. The models used in these experiences were also from the Integrated Graphics Operations and Analysis Lab model database. The PlaySpace experience incorporates surface data obtained from NASA rovers and satellites and was built by NASA JPL.

Goza, Sharon↗

VML 3.0 Reactive Sequencing Objects and Matrix Math Operations for Attitude Profiling

VML (Virtual Machine Language) has been used as the sequencing flight software on over a dozen JPL deep-space missions, most recently flying on GRAIL and JUNO. In conjunction with the NASA SBIR entitled "Reactive Rendezvous and Docking Sequencer", VML version 3.0 has been enhanced to include object-oriented element organization, built-in queuing operations, and sophisticated matrix / vector operations. These improvements allow VML scripts to easily perform much of the work that formerly would have required a great deal of expensive flight software development to realize. Autonomous turning and tracking makes considerable use of new VML features. Profiles generated by flight software are managed using object-oriented VML data constructs executed in discrete time by the VML flight software. VML vector and matrix operations provide the ability to calculate and supply quaternions to the attitude controller flight software which produces torque requests. Using VML-based attitude planning components eliminates flight software development effort, and reduces corresponding costs. In addition, the direct management of the quaternions allows turning and tracking to be tied in with sophisticated high-level VML state machines. These state machines provide autonomous management of spacecraft operations during critical tasks like a hypothetic Mars sample return rendezvous and docking. State machines created for autonomous science observations can also use this sort of attitude planning system, allowing heightened autonomy levels to reduce operations costs. VML state machines cannot be considered merely sequences - they are reactive logic constructs capable of autonomous decision making within a well-defined domain. The state machine approach enabled by VML 3.0 is progressing toward flight capability with a wide array of applicable mission activities.

VML (Virtual Machine Language)↗

Medical Physics Leadership Academy Journal Club (Leadership Club) program: Two-year review in building a community of leaders

The American Association of Physicists in Medicine began the Medical Physics Leadership Academy Journal Club in the fall of 2020. The initiative was launched to provide a forum for medical physicists to learn about leadership topics using published material, discuss and reflect on the material, and consider incorporating the discussed skills into their professional practice. This report presents the framework for the MPLA Journal Club program, describes the lessons learned over the last 2 years, summarizes the data collected from attendees, and highlights the roadmap for the program moving forward.

99 GENERAL AND MISCELLANEOUS↗

Parallel quantum computing simulations via quantum accelerator platform virtualization

Quantum circuit execution is a central task in quantum computation. Due to inherent quantum-mechanical constraints, quantum computing workflows often involve a considerable number of independent measurements over a large set of slightly different quantum circuits. Here we discuss a simple model for parallelizing such quantum circuit executions that is based on introducing a large array of virtual quantum processing units (mapped to HPC nodes in our case) as a parallel quantum computing platform. Implemented within the XACC framework, the model can readily take advantage of its backend-agnostic features, enabling parallel quantum computing/simulation over any target backend supported by XACC. We illustrate the performance of this approach by demonstrating strong scaling in two pertinent domain science problems, namely in computing the gradients for the multi-contracted variational quantum eigensolver and in data-driven quantum circuit learning, where we vary the number of qubits and the number of circuit layers. Here, the latter simulation leverages the cuQuantum library to run efficiently on GPU-accelerated HPC platforms.

97 MATHEMATICS AND COMPUTING↗

GAHLS: an optimized graph analytics based high level synthesis framework

The urgent need for low latency, high-compute and low power on-board intelligence in autonomous systems, cyber-physical systems, robotics, edge computing, evolvable computing, and complex data science calls for determining the optimal amount and type of specialized hardware together with reconfigurability capabilities. With these goals in mind, we propose a novel comprehensive graph analytics based high level synthesis (GAHLS) framework that efficiently analyzes complex high level programs through a combined compiler-based approach and graph theoretic optimization and synthesizes them into message passing domain-specific accelerators. This GAHLS framework first constructs a compiler-assisted dependency graph (CaDG) from low level virtual machine (LLVM) intermediate representation (IR) of high level programs and converts it into a hardware friendly description representation. Next, the GAHLS framework performs a memory design space exploration while account for the identified computational properties from the CaDG and optimizing the system performance for higher bandwidth. The GAHLS framework also performs a robust optimization to identify the CaDG subgraphs with similar computational structures and aggregate them into intelligent processing clusters in order to optimize the usage of underlying hardware resources. Finally, the GAHLS framework synthesizes this compressed specialized CaDG into processing elements while optimizing the system performance and area metrics. Evaluations of the GAHLS framework on several real-life applications (e.g., deep learning, brain machine interfaces) demonstrate that it provides 14.27× performance improvements compared to state-of-the-art approaches such as LegUp 6.2.

97 MATHEMATICS AND COMPUTING↗

Scanning Probe Microscopy in the Information Age

Scanning probe microscopy (SPM) has brought scientific exploration, visualization, and control to nanoscale. A plethora of measurement approaches and techniques devised around SPM enabled probing structure and functionalities crucial for virtually all areas of science. While high-resolution electron microscopy techniques preceded scanning probes, SPM effectively opened the door to probing the structure–property relationship on length scales spanning 100s of micrometers down to a single atom. As the complexity of the material systems and the scientific questions increased, so too did the SPM techniques. Substantial efforts have been dedicated toward the development of better instrumentation platforms, probes, and novel spectroscopic measurements; however, many opportunities related to data processing and acquisition in SPM are just being realized now. This chapter will describe the recent progress in data-driven SPM by giving a broad overview of the field, the foundation of the scanning tunneling microscope (STM) and the atomic force microscope (AFM), as well as a description behind the operating principles and dynamic modes. A comprehensive overview of the multi-frequency techniques, Band excitation, and general acquisition mode SPM is given, setting the context for the application of big data, machine learning, and artificial intelligence in the field of dynamic SPM.

Collins, Liam↗

SmallTAL: Real-Time Egocentric Online Temporal Action Localization for the Data-Impoverished

Abstract We propose a real-time, online temporal action localization system that requires a small amount of annotated data. The main challenges we address are high intra-class variability and a large and diverse background class. We address these using a flexible frame descriptor, dynamic time warping, and a novel approach to database construction. Our solution receives egocentric RGB-D streams as input and makes predictions at regular temporal intervals. We validate our approach by localizing actions in a digital twin of an electrical substation, in which certain objects have been replaced by functional virtual replicas.

Computer Science↗