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At least 1,765 records · Page 98

A public website for the automated assessment and validation of SARS-CoV-2 diagnostic PCR assays

Abstract Summary Polymerase chain reaction-based assays are the current gold standard for detecting and diagnosing SARS-CoV-2. However, as SARS-CoV-2 mutates, we need to constantly assess whether existing PCR-based assays will continue to detect all known viral strains. To enable the continuous monitoring of SARS-CoV-2 assays, we have developed a web-based assay validation algorithm that checks existing PCR-based assays against the ever-expanding genome databases for SARS-CoV-2 using both thermodynamic and edit-distance metrics. The assay-screening results are displayed as a heatmap, showing the number of mismatches between each detection and each SARS-CoV-2 genome sequence. Using a mismatch threshold to define detection failure, assay performance is summarized with the true-positive rate (recall) to simplify assay comparisons. Availability and implementation The assay evaluation website and supporting software are Open Source and freely available at https://covid19.edgebioinformatics.org/#/assayValidation, https://github.com/jgans/thermonucleotide BLAST and https://github.com/LANL-Bioinformatics/assay_validation. Supplementary information Supplementary data are available at Bioinformatics online.

59 BASIC BIOLOGICAL SCIENCES↗

A Framework for Model Validation and Calibration of Microgrid Components Using PMU Data

This paper presents a framework for phasor measurement-based component model validation and calibration islanded microgrids, with emphasis on grid-forming inverters. Real measurements from the Plum Island microgrid facility are used to calibrate the model of a commercial inverter in the open-source phasor-based distribution system simulator GridLAB-D.Limitations of current distribution system simulators in replicating the behavior of commercial inverters are also identified.

microgrid, Synchrophasor data, model validation↗

Validation of Power Distribution Models using Load Flow Analysis in an ADMS Environment

Electric utilities are facing the need for better monitoring, analysis, and control of their distribution systems. An accurate mathematical model is a key to both the development of cutting-edge, scalable model-based algorithms and the assessment of emerging technologies such as distributed energy resources (DER) for grid planning and operation. However, the constantly evolving nature of power distribution systems poses challenges to maintaining accurate models. In this paper, we propose a novel load flow based approach to validate power distribution models. Networked equipment models described according to the Common Information Model (CIM) standard and a measurement model are used to formulate the distribution load flow problem. First, a system admittance matrix (Ybus) is derived from device-level CIM parameters. Next, the operational parameters (dynamic Ybus and nodal injections) are extracted from the measurement model using sensor configuration and equipment state. An iterative power flow method is then used to compute nodal voltages and branch flows that are compared against the measurement data to find any inconsistencies in the networked equipment model. This approach is implemented within GridAPPS-D, an open-source standards-based platform for advanced distribution management system (ADMS) application development, and demonstrated on the IEEE 13-bus, 123-bus, and 8500-node test feeders.

Common information model, model validation, power ↗

Validation of the Fault Ride-Through Response of a Generic EMT Inverter Model by Laboratory Testing

This paper presents the validation of the fault ride-through response of a large-scale inverter model using laboratory testing of a commercial inverter. First, we present the generic inverter model specifications. The generic inverter control is developed based on the fault ride-through response performance requirements of IEEE Std 2800-2022 for inverter-based resources. Next, we present laboratory tests that emulate voltages at the inverter terminal resulting from balanced and unbalanced faults on the transmission system. The tests are performed on a commercia12.2 MVA battery storage inverter at the U.S. National Renewable Energy Laboratory. Comparisons of the model's response to the laboratory measurements show the generic model presented can predict the controlled response of the commercial equipment. The differences between the model's response and the laboratory measurements during the initial transient at fault inception are discussed.

fault ride-through↗

A CHIL Validation of Machine Learning-Assisted Methods for Real-Time Controls of Solar PV for Grid Services

Recent research has highlighted the potential for solar to act as a zero-marginal-cost and zero-emission flexibility resource on the bulk power system when operated with advanced control systems. To increase the performance of these systems, leading technologies, including machine learning (ML) and hierarchical inverter set point allocation, have been proposed; however, these technologies lack comprehensive validation under real-world application scenarios. This paper addresses this gap by designing and developing a controller-hardware-in-the-loop framework to evaluate the performance of different flexible solar technologies in responding to automatic generation control signals in a closed-loop fashion. Simulation results indicate the superior performance of an ML-based approach compared to the conventional reference-control grouping-based approach, showcasing its potential to support grid stability and operational efficiency.

closed-loop validation↗

Verified, Archived, Library of Inputs and Data (VALID) Supporting Files

This dataset contains input, output, and sensitivity data files for computational simulations with the SCALE code system as part of the Verified, Archived Library of Inputs and Data (VALID). The simulations cover critical benchmark experiments from the International Criticality Safety Benchmark Evaluation Project. The files are to be housed in a public directory for distribution. The information contained in the files have been approved for release by the Organisation for Economic Co-operation and Development Nuclear Energy Agency (NEA). Users wanting to reproduce results from this dataset are required to obtain a license to the SCALE code system for which details on the distribution can be found here: https://www.ornl.gov/scale/releases.

keff↗

Cross Validation of the Network of Ground-Based Radar with GPM during the Remote Sensing of Electrification, Lightning, And Mesoscale/Microscale Processes with Adaptive Ground Observations (RELAMPAGO) Field Campaign

The cross-validation of radars in a network is important in making consistent retrievals across the domain and assuring the product quality. During the RELAMPAGO field campaign, two C-band radars, namely the Colorado State University C-band Hydrological Instrument for Volumetric Observations ( CSU-CHIVO) and the C-band Scanning ARM Precipitation Radar (CSAPR-2), were deployed near the Sierras de Cordoba in Argentina, a region known for having some of the most intense severe weather in the world. In addition to these two radars, the operational radar of the Cordoba City, the Radar Meteorologico Argentino 1 (RMA-1), adds another instrument to the RELAMPAGO network. This study presents an intercomparison between the RELAMPAGO C-band radars using the GPM spaceborne radar as a common reference ..A method to bring ground-based radars into better agreement is also proposed. Moreover, the attenuation correction for the C-band radar is studied in the context of intercomparing two radars. The attenuation coefficients are computed for the RELAMPAGO domain using the local disdrometers deployed. during the campaign. After the attenuation correction, CSU-CHIVO, CSAPR-2, and RMA-1 compare well with GPM-DPR with a high correlation and bias less than 1 dB.

54 ENVIRONMENTAL SCIENCES↗

The Verification and Validation Strategy Within the Second Wind Forecast Improvement Project (WFIP 2)

The Wind Forecast Improvement Project 2 (WFIP2), in the complex terrain of the Columbia Gorge, focuses on a set of weather phenomena that poses particular challenges for wind and wind power forecasting. It further aims to understand and improve the skill of weather forecast models, particularly the National Oceanic and Atmospheric Administration's (NOAA's) High Resolution Rapid Refresh (HRRR), in complex terrain. The project also includes an extensive field campaign in the Columbia River Gorge, during which data from many different instruments were collected. WFIP2 is funded by the U.S. Department of Energy (DOE). Scientists from four U.S. national laboratories, NOAA, Vaisala, and universities contribute to the project with wide and varied interests and skill sets. Therefore, coordinated verification & validation (V&V) efforts across these members allows for the development of a clear picture of model improvements and scientific findings within WFIP2. The WFIP2 V&V team is tasked with providing tools, methods, and guidance to enable repeatable, metrics-based assessment of the Weather Research and Forecasting (WRF) model and associated modeling suites for analysis and forecasting of mesoscale weather phenomena that are important for wind energy in the Columbia River Gorge and other parts of the continental United States. This report summarizes what has been worked on and accomplished within the duration of the WFIP2 project, 4 years, by the V&V team.

17 WIND ENERGY↗

Energy Performance Validation of a Gaseous Air Cleaning Technology for Commercial Buildings

The U.S. Department of Energy (DOE) Building Technologies Office Commercial Building Integration group conducts evaluations of new energy efficiency technologies as part of the High Impact Technology Catalyst program. The subject of this field validation project is an air cleaning technology that removes gaseous contaminants from indoor air to reduce outdoor air ventilation requirements. Reducing the volume of outdoor air required reduces heating, ventilating, and air conditioning (HVAC) loads and can provide significant energy savings for some buildings in certain climates. The technology, called the HLR (HVAC Load Reduction), was developed by enVerid. The technology uses a solid regenerable sorbent material that was developed by DOE's National Energy Technology Laboratory and licensed to the vendor for this application. The sorbent material was originally developed to adsorb carbon dioxide (CO2); the vendor continued to develop the sorbent and the overall system so that it can also remove volatile organic compounds (including aldehydes), carbon monoxide, ozone, and particulate matter 2.5 micrometers in diameter or smaller (PM2.5) from the air. This material has low regeneration temperature requirements, and its sorption properties are unaffected by humidity levels, both of which are beneficial for building applications.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Validation of SolarWorld Modules at the NREL Regional Test Center Site (CRADA CRD-15-595 Final Report)

SolarWorld and the National Renewable Energy Laboratory (NREL) are entering into a cooperative research and development agreement (CRADA) in order to perform validation testing of SolarWorld’s Photovoltaic (PV) modules through the Department of Energy (DOE) Regional Test Center (RTC) program. This CRADA describes testing activities conducted specifically at the NREL-managed Colorado RTC site.

14 SOLAR ENERGY↗

Best Practices for the Validation of U.S. Offshore Wind Resource Models

This report presents a comprehensive set of best practices for working with both modeled and measured US offshore wind resource data sets. We specifically target two key questions in this report. First, what are the best data sources and methods for validating modeled wind resource estimates? Second, what are the best methods for vertically extrapolating near-surface wind speed measurements to heights that span the rotor-swept area of modern offshore wind turbines?

17 WIND ENERGY↗

Rapid Construction of Validated Chemistry Models for Advanced Biofuels (Co-Optima Final Report)

Computer methods were developed and demonstrated that make it possible to predict the combustion and pyrolysis chemistry of proposed biofuels, even before the biofuels are ever manufactured or experimentally tested. The methods are based on first-principles calculations of reaction rates and equilibria. A large number of complicated calculations are required, so we developed a computer workflow that automates many of the steps. With the chemical structure of the biofuel and the system conditions (temperature, pressure, compositions, etc.) as the input, the computer methods can construct a detailed kinetic model with refined parameters without intense human intervention. The automation of model construction makes it practical for a single engineer to make the predictions in a reasonable time period. The accuracy of the computer predictions was tested by measuring the time-profiles of various reaction intermediates (carbon monoxide, carbon dioxide, water, formaldehyde, methane, and ethylene) formed as the biofuels pyrolyze or ignite using sophisticated laser shock tube methods. Several biofuels, including methyl propyl ether, cyclopentanone, butyl acetate isomers, etc., were carefully studied to demonstrate the validity of the proposed computational and experimental methodology. This research project opens up the possibility for assessing some proposed biofuels on the computer without expensive experimental campaigns. The new computer methods are open source and well-documented, allowing a knowledgeable modeler to easily access the developed methods and implement them in their work routine. Moreover, they are also convenient and powerful, promising for developing the fuel chemistry models needed for use in engine simulators, facilitating co-optimization of new engine designs with new fuels.

09 BIOMASS FUELS↗

Field Validation of Air-Source Heat Pumps for Cold Climates

Heating energy is the largest end-use for U.S. residential buildings accounting for approximately one-third of residential building energy consumption (EIA 2021). Historically, air-source heat pumps have been limited to temperate climates because of subpar performance at extremely cold outdoor air temperatures. However, recent advances to cold-climate air-source heat pump technology, which typically rely on inverter-driven, variable-speed compressors and variable-speed fans, have significantly improved low-temperature heat pump performance enabling the technology to save energy for many homes in cold climates. The primary objective of this project was to measure in-field performance of centrally ducted, variable-capacity air-source heat pumps in cold climates to validate performance and develop field-based performance maps. The project focused on quantifying heat pump performance at cold temperatures. The sites identified for the study were primarily located in the Northwest United States since homes in the region tend to have all-electric space heating systems and high-efficiency heat pumps have been incentivized in the region for several years. NREL partnered with Ecotope, Inc., a small energy consulting firm located in Seattle, WA, for site recruitment, monitoring equipment installation, data quality management. All the sites included in the study had previously installed a high-efficiency, central heat pump system. One site was in a Denver, CO suburb, which was the only dual fuel heat pump in the study. We used airside and power measurements, collected at 5-second intervals, to quantify heat pump capacity, coefficient of performance (COP), and auxiliary heater energy consumption. We developed algorithms to automatically determine the heat pump operating mode including defrost and auxiliary heating operation. A whole-house thermal and duct audit was completed during the initial site visit to estimate winter heating loads and assess heat pump sizing. Whole-home heating design loads were calculated at ASHRAE 99% design temperatures and compared to manufacturer-reported maximum capacities to assess the heat pump sizing at each site.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Verification and Validation for Energy System Co-Design and Simulation

This project was only active for two months and was terminated due to a re-organization of the sponsoring initiative. The original purpose of the project was to develop and apply verification and validation (V&V) methodologies for the Energy System Co-Design with Multiple Objectives and Power Electronics (E-COMP) Initiative. This report summarizes the project and the work that was completed in the shortened time frame.

42 ENGINEERING↗

Floating PV Potential and Technology Validation [Slides]

This presentation covers, at a high-level, the potential for floating solar PV (FPV) in the United States as well as technology validation approaches and research capabilities at the U.S. Department of Energy's National Renewable Energy Laboratory (NREL).

14 SOLAR ENERGY↗

Chicago Energy Efficiency Planning and Analysis and Integrated Retrofit Strategy Validation in Single-Family Homes

In June 2020, the project team comprised of Elevate and the National Renewable Energy Laboratory (NREL), with advisory roles from the City of Chicago and Commonwealth Edison, initiated a three-year project with the U.S. Department of Energy to inform communitywide energy planning at a local scale and validate advanced retrofit packages that achieve at least 50% energy savings in existing homes. The project team has characterized Chicago’s single-family and 2-4 unit housing stock and energy use using the ResStock™ modeling tool, and with that information developed advanced whole home energy retrofit packages for single family and 2-4 unit homes that can reduce energy use by at least 50% and support climate, air quality, and other goals. This report presents an analysis of the technical potential of applying these retrofit packages at a City-wide scale, and a roadmap for rapidly scaling up retrofit programs to improve Chicago’s housing stock and target investments in the neighborhoods that need it most. The main goals of the analysis are to: 1) develop a Chicago-specific single-family and 2-4 unit building retrofit prioritization strategy; 2) identify opportunities for beneficial electrification in communities and home types that stand to benefit most; and 3) assess costs and savings potential for retrofit investments at a household and city scale, in terms of energy use, bill impacts, carbon emissions, and other outcomes.

14 SOLAR ENERGY↗

1D Heat Loss Models Validation Experiment

Contains data from the model validation in the 1D Heat Loss Models to Predict the Aquifer Temperature Profile during Hot/Cold Water Injection Project. The data include two COMSOL models (2D axisymmetric benchmark model and 2D Vinsome model), one python code (1D Vinsome based FEM numerical simulation), one matlab main code (1D Newton analytical solution and all results comparison visualization), and output files generated from the above models.

1D↗