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At least 1,765 records · Page 98

Lateral optical confinement of channeled-substrate-planar lasers with GaAs/AlGaAs substrates

A physical explanation of the lateral guiding mechanism in channeled-substrate-planar (CSP) lasers based on the amount of wavefront tilt of the transverse field outside the channel region is presented. Because of this inherent wavefront tilt, all CSP lasers will have a very slight asymmetry in their transverse far-field pattern. The nature of the guiding mechanism does not require light absorption by the substrate. Design curves showing the complex lateral effective index step as a function of n-clad thickness with the active layer as a parameter are also presented. Depending on the specific layer compositions and thicknesses, the CSP guiding mechanism can provide a positive lateral index step for substrates with mole fractions of AlAs ranging from 0 to higher than 0.2.

Evans, Gary A.↗

Fault tolerant system performance modeling

With the proliferation of complex digital systems on aircraft, the need to accurately predict system performance early in the system design cycle becomes imperative. In the past, system designers have relied on ad hoc methods for evaluating performance issues. This has produced systems that have not always worked as originally intended. To alleviate these design deficiencies, formal methods, with supporting tools, must be adhered to during the system design process. The use of performance modeling tools is becoming widely accepted as a way to address timing considerations of system design. An additional incentive for the use of these tools is that they allow the system architect to analyze system component interactions (i.e., bus contention, contention of functions for a processing site, and system repair activity on application performance). This inherent flexibility can result in an explicit specification of the system architecture. This paper addresses a method that supports performance modeling of fault tolerant systems using a discrete event simulation tool. An additional focus is on lessons learned from analyzing these classes of problems. The methodology and supporting work provide system architects with the capability to specify candidate architectures and accurately predict their performance in the early stages of design, where changes to system design is most cost effective. The work has been supported under NASA contract NAS1-18099. Integrated Airframe Propulsion Control System Architecture (IAPSA II). This contract addresses methodology, analysis, and detailed design of integrated control system architectures suitable for high-performance aircraft of the 1990's.

Discrete event simulation↗

Elements of designing for cost

During recent history in the United States, government systems development has been performance driven. As a result, systems within a class have experienced exponentially increasing cost over time in fixed year dollars. Moreover, little emphasis has been placed on reducing cost. This paper defines designing for cost and presents several tools which, if used in the engineering process, offer the promise of reducing cost. Although other potential tools exist for designing for cost, this paper focuses on rules of thumb, quality function deployment, Taguchi methods, concurrent engineering, and activity-based costing. Each of these tools has been demonstrated to reduce cost if used within the engineering process.

Dean, Edwin B.↗

Hot Hydrogen Testing of Refractory Metals and Ceramics

The objective of this investigation is to develop a technique with which refractory metal carbide samples can be exposed to hydrogen containing gases at high temperatures, and to use various microstructural and analytical techniques to determine the chemical and rate processes involved in hydrogen degradation in these materials. Five types of carbides were examined including WC, NbC, HfC, ZrC, and TaC. The ceramics were purchased and were all monolithic in nature. The temperature range investigated was from 850 to 1600 C with a hydrogen pressure of one atmosphere. Control experiments, in vacuum, were also conducted for comparison so that the net effects due to hydrogen could be isolated. The samples were analyzed prior to and after exposure. Gas samples were collected in selected experiments and analyzed using gas chromography. Characterization of the resulting microstructure after exposure to hydrogen was conducted using optical microscopy, x-ray diffraction, scanning electron microscopy, and weight change. The ceramics were purchased and were all monolithic in nature. It was found that all samples lost weight after exposure, both in hydrogen and vacuum. Results from the microstructure analyses show that the degradation processes are different among the five types of ceramics involved. In addition, the apparent activation energy for the degradation process is a function of temperature even within the same material. This indicates that there are more than one mechanism involved in each material, and that the mechanisms are temperature dependent.

Zee, Ralph↗

Genopersistating the system

The concept of competitiveness is considered as a function of both high quality and low cost, and the techniques which drive a design simultaneously in both directions. In order to examine these techniques, the term 'genopersistation', which is derived from the words 'genesis' and 'persistence' and defined to mean the bringing forth, sustaining, and eventual annihilation of something. For a product, the term includes the conceptual design, design development, test and evaluation, production, deployment, operation, support, evolution, and retirement of product. The techniques are summarized which can be used to simultaneously genopersistate both the high quality and low cost into a product. Attention is given to Taguchi (1986) methods, the response surface methodology (Montgomery, 1984), Quality Function Deployment (Akao, 1990), Hoshin Kanari (Akao, 1991), activity based costing (O'Guin, 1991), concurrent engineering (Carter and Baker, 1991), and multidisciplinary optimization (Evans, 1984).

Dean, Edwin B.↗

Ab initio study of Fe(+)-benzyne

The interaction of Fe(+) with benzyne is studied using the self-consistent-field (SCF), complete active space SCF, and modified-coupled-pair functional levels of theory. The most stable structure is planar, where the Fe(+) has inserted into the in-plane pi bond, although the C-C bond distance suggests that some in-plane pi bonding remains. This system is compared with Sc(+) bonding to benzyne and other ligands.

Bauschlicher, Charles W., Jr.↗

A note on two-dimensional asymptotic magnetotail equilibria

In order to understand, on the fluid level, the structure, the time evolution, and the stability of current sheets, such as the magnetotail plasma sheet in Earth's magnetosphere, one has to consider magnetic field configurations that are in magnetohydrodynamic (MHD) force equilibrium. Any reasonable MHD current sheet model has to be two-dimensional, at least in an asymptotic sense (B(sub z)/B (sub x)) = epsilon much less than 1. The necessary two-dimensionality is described by a rather arbitrary function f(x). We utilize the free function f(x) to construct two-dimensional magnetotail equilibria are 'equivalent' to current sheets in empirical three-dimensional models. We obtain a class of asymptotic magnetotail equilibria ordered with respect to the magnetic disturbance index Kp. For low Kp values the two-dimensional MHD equilibria reflect some of the realistic, observation-based, aspects of three-dimensional models. For high Kp values the three-dimensional models do not fit the asymptotic MHD equlibria, which is indicative of their inconsistency with the assumed pressure function. This, in turn, implies that high magnetic activity levels of the real magnetosphere might be ruled by thermodynamic conditions different from local thermodynamic equilibrium.

Voigt, Gerd-Hannes↗

Active region seismology

Active region seismology is concerned with the determination and interpretation of the interaction of the solar acoustic oscillations with near-surface target structures, such as magnetic flux concentration, sunspots, and plage. Recent observations made with a high spatial resolution and a long temporal duration enabled measurements of the scattering matrix for sunspots and solar active regions to be carried out as a function of the mode properties. Based on this information, the amount of p-mode absorption, partial-wave phase shift, and mode mixing introduced by the sunspot, could be determined. In addition, the possibility of detecting the presence of completely submerged magnetic fields was raised, and new procedures for performing acoustic holography of the solar interior are being developed. The accumulating evidence points to the mode conversion of p-modes to various magneto-atmospheric waves within the magnetic flux concentration as being the unifying physical mechanism responsible for these diverse phenomena.

Bogdan, Tom↗

End-to-End System Test and Optical Performance Evaluation for the Solar and Heliosphere Observatory (SOHO) Ultraviolet Coronagraph Spectrometer (UVCS)

The UVCS is one of the instruments carried by the Solar and Heliospheric Observatory (SOHO), a joint NASA/ESA Spacecraft launched in November 1995. It is designed to perform ultraviolet spectroscopy and visible light polarimetry of the extended solar corona. The primary scientific objectives of the UVCS investigation are to study the physical processes occurring in the extended solar corona, such as: the mechanism of acceleration of the solar wind, the mechanism of coronal plasma heating, the identification of solar wind sources, and the investigation of the plasma properties of the solar wind. The UVCS End-to-End test activities included a comprehensive set of system level functional and optical tests. Although performed under severe schedule constraints, the End-to-End System Test was very successful and served to fully validate the UVCS optical design. All test results showed that the primary scientific objectives of the UVCS Mission were achievable.

Carosso, Paolo A.↗

Stationary Wave Activity Simulated by the NASA Ames MGCM Incorporating New MOLA Topography Data

Annual simulations of Mars' atmosphere have been conducted with the NASA Ames Mars General Circulation Model (MGCM) using the newly-acquired MOLA topography data. The data is provided at 1 x 1 deg resolution, and is used by the MGCM at 7.5 x 9 deg resolution. The vertical domain in the simulations reported here extends to around 80 km. Simulated stationary wave activity is examined in each hemisphere as a function of season (at every 30 deg of Ls), dust loading (dust visible opacities of 0.3, 1, and 3), and topography (comparing results with MOLA vs. Smith-Zuber topography). Additional information is contained in the original extended abstract.

Bridger, A. F. C.↗

STS-112 Crew Interviews - Magnus

STS-112 Mission Specialist 2 Sandra H. Magnus is seen during a prelaunch interview. She answers questions about her inspiration to become an astronaut and her career path. She gives details on the mission's goals, the most significant of which will be the installation of the S-1 truss structure on the International Space Station (ISS). The installation, one in a series of truss extending missions, will be complicated and will require the use of the robotic arm as well as extravehicular activity (EVA) by astronauts. Magnus also describes her function in the performance of transfer operations. Brief descriptions are given of experiments on board the ISS as well as on board the Shuttle.

Source record↗

Purification and Crystallization of Murine Myostatin: A Negative Regulator of Muscle Mass

Myostatin (MSTN) has been crystallized and its preliminary X-ray diffraction data were collected. MSTN is a negative regulator of muscle growt/differentiation and suppressor of fat accumulation. It is a member of TGF-b family of proteins. Like other members of this family, the regulation of MSTN is critically tied to its process of maturation. This process involves the formation of a homodimer followed by two proteolytic steps. The first proteolytic cleavage produces a species where the n-terminal portion of the dimer is covalently separated from, but remains non-covalently bound to, the c-terminal, functional, portion of the protein. The protein is activated upon removal of the n-terminal "pro-segment" by a second n-terminal proteolytic cut by BMP-1 in vivo, or by acid treatment in vitro. Understanding the structural nature and physical interactions involved in these regulatory processes is the objective of our studies. Murine MSTN was purified from culture media of genetically engineered Chinese Hamster Ovary cells by multicolumn purification process and crystallized using the vapor diffusion method.

Hong, Young S.↗

Radiation-induced gene expression in the nematode Caenorhabditis elegans

We used the nematode C. elegans to characterize the genotoxic and cytotoxic effects of ionizing radiation in a simple animal model emphasizing the unique effects of charged particle radiation. Here we demonstrate by RT-PCR differential display and whole genome microarray hybridization experiments that gamma rays, accelerated protons and iron ions at the same physical dose lead to unique transcription profiles. 599 of 17871 genes analyzed (3.4%) showed differential expression 3 hrs after exposure to 3 Gy of radiation. 193 were up-regulated, 406 were down-regulated and 90% were affected only by a single species of radiation. A novel statistical clustering technique identified the regulatory relationships between the radiation-modulated genes and showed that genes affected by each radiation species were associated with unique regulatory clusters. This suggests that independent homeostatic mechanisms are activated in response to radiation exposure as a function of track structure or ionization density.

Non-NASA Center↗

Autoinhibition of a calmodulin-dependent calcium pump involves a structure in the stalk that connects the transmembrane domain to the ATPase catalytic domain

The regulation of Ca(2+)-pumps is important for controlling [Ca(2+)] in the cytosol and organelles of all eukaryotes. Here, we report a genetic strategy to identify residues that function in autoinhibition of a novel calmodulin-activated Ca(2+)-pump with an N-terminal regulatory domain (isoform ACA2 from Arabidopsis). Mutant pumps with constitutive activity were identified by complementation of a yeast (K616) deficient in two Ca(2+)-pumps. Fifteen mutations were found that disrupted a segment of the N-terminal autoinhibitor located between Lys(23) and Arg(54). Three mutations (E167K, D219N, and E341K) were found associated with the stalk that connects the ATPase catalytic domain (head) and with the transmembrane domain. Enzyme assays indicated that the stalk mutations resulted in calmodulin-independent activity, with V(max), K(mATP), and K(mCa(2+)) similar to that of a pump in which the N-terminal autoinhibitor had been deleted. A highly conservative substitution at Asp(219) (D219E) still produced a deregulated pump, indicating that the autoinhibitory structure in the stalk is highly sensitive to perturbation. In plasma membrane H(+)-ATPases from yeast and plants, similarly positioned mutations resulted in hyperactive pumps. Together, these results suggest that a structural feature of the stalk is of general importance in regulating diverse P-type ATPases.

NASA Discipline Plant Biology↗

Contribution of the cerebellar flocculus to gaze control during active head movements

The flocculus and ventral paraflocculus are adjacent regions of the cerebellar cortex that are essential for controlling smooth pursuit eye movements and for altering the performance of the vestibulo-ocular reflex (VOR). The question addressed in this study is whether these regions of the cerebellum are more globally involved in controlling gaze, regardless of whether eye or active head movements are used to pursue moving visual targets. Single-unit recordings were obtained from Purkinje (Pk) cells in the floccular region of squirrel monkeys that were trained to fixate and pursue small visual targets. Cell firing rate was recorded during smooth pursuit eye movements, cancellation of the VOR, combined eye-head pursuit, and spontaneous gaze shifts in the absence of targets. Pk cells were found to be much less sensitive to gaze velocity during combined eye-head pursuit than during ocular pursuit. They were not sensitive to gaze or head velocity during gaze saccades. Temporary inactivation of the floccular region by muscimol injection compromised ocular pursuit but had little effect on the ability of monkeys to pursue visual targets with head movements or to cancel the VOR during active head movements. Thus the signals produced by Pk cells in the floccular region are necessary for controlling smooth pursuit eye movements but not for coordinating gaze during active head movements. The results imply that individual functional modules in the cerebellar cortex are less involved in the global organization and coordination of movements than with parametric control of movements produced by a specific part of the body.

NASA Discipline Neuroscience↗

Laser Beam Steering/shaping for Free Space Optical Communication

The 2-D Optical Phased Array (OPA) antenna based on a Liquid Crystal On Silicon (LCoS) device can be considered for use in free space optical communication as an active beam controlling device. Several examples of the functionality of the device include: beam steering in the horizontal and elevation direction; high resolution wavefront compensation in a large telescope; and beam shaping with the computer generated kinoform. Various issues related to the diffraction efficiency, steering range, steering accuracy as well as the magnitude of wavefront compensation are discussed.

Wang, Xinghua↗

The MSFC Systems Engineering Guide: An Overview and Plan

As systems and subsystems requirements become more complex in the pursuit of the exploration of space, advanced technology will demand and require an integrated approach to the design and development of safe and successful space vehicles and there products. System engineers play a vital and key role in transforming mission needs into vehicle requirements that can be verified and validated. This will result in a safe and cost effective design that will satisfy the mission schedule. A key to successful vehicle design within systems engineering is communication. Communication, through a systems engineering infrastructure, will not only ensure that customers and stakeholders are satisfied but will also assist in identifying vehicle requirements; i.e. identification, integration and management. This vehicle design will produce a system that is verifiable, traceable, and effectively satisfies cost, schedule, performance, and risk throughout the life-cycle of the product. A communication infrastructure will bring about the integration of different engineering disciplines within vehicle design. A system utilizing these aspects will enhance system engineering performance and improve upon required activities such as Development of Requirements, Requirements Management, Functional Analysis, Test, Synthesis, Trade Studies, Documentation, and Lessons Learned to produce a successful final product. This paper will describe the guiding vision, progress to date and the plan forward for development of the Marshall Space Flight Center (MSFC) Systems Engineering Guide (SEG), a virtual systems engineering handbook and archive that will describe the system engineering processes that are used by MSFC in the development of complex systems such as the Ares launch vehicle. It is the intent of this website to be a "One Stop Shop" for our systems engineers that will provide tutorial information, an overview of processes and procedures and links to assist system engineering with guidance and references, and provide an archive of systems engineering artifacts produced by the many NASA projects developed and managed by MSFC over the years.

Shelby, Jerry A.↗

Head Tilt Posturography to Enhance Balance Control Assessment for Astronauts: A Case Study

For many years, we have used a standard clinical computerized dynamic posturography (CDP) protocol to assess recovery of integrated sensory-motor function in astronauts returning from space flight. The most reliable indications of postflight crew performance capabilities have been obtained from the sensory organization tests (SOTs) within the CDP protocol, particularly SOTs 5 (eyes closed, surface support sway referenced) and 6 (eyes open, surface support and visual surround sway referenced), which are sensitive to changes in availability and/or utilization of vestibular cues. We have observed, however, that some astronauts exhibiting visible signs of incomplete sensory-motor recovery are able to score within clinical norms on standard SOTs 5 and 6 trials, perhaps as a result of cognitive strategies driven by their naturally competitive natures. To improve the sensitivity of the CDP protocol for assessing recovery of integrated sensory-motor function and fitness to return to duties and/or activities of daily living, we have introduced pitch plane head tilt SOT trials to our protocol. In a preliminary study of 5 short duration (~11day missions) astronauts, we showed that they were unable to maintain balance on landing day when performing dynamic head tilt trials, despite scoring within the clinically normal range on the standard SOT trials. The present case report illustrates the advantages of including head tilt trials for assessing sensory-motor recovery in long duration crewmembers.

Hwang, E. Y.↗