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Results for “Reversible”
Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Control of polarization reversal temperature behavior by surface screening in thin ferroelectric films
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Life testing of 10 cm × 10 cm fuel-electrode-supported solid oxide cells in reversible operation
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Repairing large cracks and reversing fatigue damage in structural metals
Self-healing materials represent a paradigm shift from traditional materials development, enabling intrinsic repair of functionality (such as strength) after a catastrophic failure as opposed to part replacement. Several healing mechanisms have been demonstrated in polymeric and ceramic materials, but few in metallic systems. This study demonstrates a novel liquid-assisted self-healing metal-matrix composite (MMC) designed to be capable of over 90% strength recovery after a healing cycle. The aluminum (Al)-based matrix is reinforced with continuous nickel-titanium (NiTi) shape-memory alloy (SMA) reinforcements. Using a tailored heat treatment for healing, a paired effect of crack closure from the SMA reinforcement and partial liquefaction of the matrix occurs. These effects result in a compressive force across the crack surface, and, coupled with increased diffusion rates from the liquefied matrix, produces consolidation and healing in the composite structure. This work provides experimental and computational evidence for the healing mechanism under both tensile and fatigue conditions.
Heat exchanger circuitry optimization using an enhanced integer permutation-based genetic algorithm in low-GWP reversible heat pump applications
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Local protein flexibility as a prerequisite for reversible chromophore isomerization in [alpha]-phycoerythrocyanin
Abstract not provided
Irisin reverses platelet derived growth factor-BB-induced vascular smooth muscle cells phenotype modulation through STAT3 signaling pathway
Vascular smooth muscle cells (VSMCs) phenotype modulation toward a synthetic phenotype is the main cause of cardiovascular disease. As a newly discovered myokine, Irisin is thought to be a promising candidate for the treatment of metabolic disturbances, as well as cardiovascular disease. However, no evidence has been shown for the direct effect of Irisin on VSMCs phenotype modulation and its underling mechanisms. The aim of this study was to explore the effect of Irisin on VSMCs phenotype modulation and the mechanisms involved. In the present study, it was found that Irisin restored the PDGF-BB-induced VSMCs phenotype modulation which exhibited down-regulation of smooth muscle cells (SMC) expression and up-regulation of matrix synthesis related marker expression, as well as proliferative phenotype. Moreover, our research demonstrated that Irisin further activated STAT3 signaling pathways. Finally, by applying an STAT3 inhibitor, WP1066, we revealed the roles of STAT3 in the PDGF-BB-induced VSMCs phenotype modulation when they were treated with Irisin. Taken together, these results demonstrated that Irisin may play a crucial role in regulating VSMCs phenotype modulation via the STAT3 signaling pathway. - Highlights: • Irisin prevents PDGF-BB-stimulated VSMCs dedifferentiation. • Irisin inhibits VSMCs towards a proliferative synthetic phenotype induced by PDGF-BB stimulation. • Irisin treatment further activates STAT3 in VSMCs. • The effect of Irisin on VSMCs phenotype modulation might be STAT3-dependent.
Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens
Abstract not provided
Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 2
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Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1
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Creating robust and reversible cell-gel networks using boronic acid chemistry.
Abstract not provided.
Self-adaptive FeP@C nanocages for reversible and long-term lithium-ion batteries
Abstract not provided
May reversible water uptake/release by hydrates explain the thermal expansion of cement paste? ÔÇö Arguments from an inverse multiscale analysis
Quasi-instantaneous thermal expansion of cement pastes is governed by the relative humidity (RH) within their air-filled pores and by the decrease/increase of this internal RH resulting from a temperature decrease/increase. The latter effect is traced back to quasi-instantaneous water uptake/release by cement hydrates, using microporomechanics and a three-scale representation of mature cement pastes. Partially saturated gel and capillary pores are considered to be connected and spherical, with radii following exponential distributions. The Mori-Tanaka scheme provides the scale transition from effective pore pressures to eigenstrains at the cement paste level. This modeling approach, together with considering mass conservation of water, allows for downscaling macroscopic thermal expansion coefficients, so as to identify the molecular water uptake/release characteristics of the hydrates. The latter characteristics are mixture-independent, as shown by their use for predicting the thermal expansion coefficients of different mature cement pastes, with w/c-ratios ranging from 0.50 to 0.70.