Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “Expression systems”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,765 records · Page 98

The primer vector in linear, relative-motion equations

Primer vector theory is used in analyzing a set of linear, relative-motion equations - the Clohessy-Wiltshire equations - to determine the criteria and necessary conditions for an optimal, N-impulse trajectory. Since the state vector for these equations is defined in terms of a linear system of ordinary differential equations, all fundamental relations defining the solution of the state and costate equations, and the necessary conditions for optimality, can be expressed in terms of elementary functions. The analysis develops the analytical criteria for improving a solution by (1) moving any dependent or independent variable in the initial and/or final orbit, and (2) adding intermediate impulses. If these criteria are violated, the theory establishes a sufficient number of analytical equations. The subsequent satisfaction of these equations will result in the optimal position vectors and times of an N-impulse trajectory. The solution is examined for the specific boundary conditions of (1) fixed-end conditions, two-impulse, and time-open transfer; (2) an orbit-to-orbit transfer; and (3) a generalized rendezvous problem. A sequence of rendezvous problems is solved to illustrate the analysis and the computational procedure.

Source record↗

The influence of differential rotation on the equatorial component of the sun's magnetic dipole field

This paper examines the effect that solar differential rotation would have on a hypothetical large-scale equatorial dipole field. The evolving large-scale field pattern is expressed as a series of non-axisymmetric moments. As time increases, power is transferred to progressively higher order moments. In the 27d rotating coordinate system, each moment undergoes a small retrograde drift which remains nearly uniform until that mode begins to fade. The synodic rotation periods of the first few moments are comparable to the observed 28.5d period of the sun's large-scale field near sunspot maximum. Differential rotation may be the source of this 28.5d period, but the eruption of new flux is necessary to keep the pattern going.

Sheeley, N. R., Jr.↗

The Sizing and Optimization Language, (SOL): Computer language for design problems

The Sizing and Optimization Language, (SOL), a new high level, special purpose computer language was developed to expedite application of numerical optimization to design problems and to make the process less error prone. SOL utilizes the ADS optimization software and provides a clear, concise syntax for describing an optimization problem, the OPTIMIZE description, which closely parallels the mathematical description of the problem. SOL offers language statements which can be used to model a design mathematically, with subroutines or code logic, and with existing FORTRAN routines. In addition, SOL provides error checking and clear output of the optimization results. Because of these language features, SOL is best suited to model and optimize a design concept when the model consits of mathematical expressions written in SOL. For such cases, SOL's unique syntax and error checking can be fully utilized. SOL is presently available for DEC VAX/VMS systems. A SOL package is available which includes the SOL compiler, runtime library routines, and a SOL reference manual.

Lucas, Stephen H.↗

Analysis of adaptive identifiers in the presence of unmodelled dynamics: Averaging and tuned parameters

The behavior of a standard identifier is analyzed for the case in which the plant contains additional dynamics, called unmodeled dynamics, which invalidate the known order assumption. An input richness condition is obtained that does not depend on the order of the unmmodeled dynamics to guarantee persistency of excitation (PE) of the regressor. It is shown that the PE condition leads to a BIBO stability property for the identifier. The method of averaging is used to define formally the notion of tuned parameters as the equilibrium of the identifier-averaged system. It is shown that the tuned parameters always exist and that the actual parameters converge to some neighborhood of the tuned parameters. An explicit expression is derived to calculate and interpret them as the fixed parameter values that minimize the mean-squared output error.

Mason, J. E.↗

An approximate solution for interlaminar stresses in laminated composites: Applied mechanics program

An approximate solution for interlaminar stresses in finite width, laminated composites subjected to uniform extensional, and bending loads is presented. The solution is based upon the principle of minimum complementary energy and an assumed, statically admissible stress state, derived by considering local material mismatch effects and global equilibrium requirements. The stresses in each layer are approximated by polynomial functions of the thickness coordinate, multiplied by combinations of exponential functions of the in-plane coordinate, expressed in terms of fourteen unknown decay parameters. Imposing the stationary condition of the laminate complementary energy with respect to the unknown variables yields a system of fourteen non-linear algebraic equations for the parameters. Newton's method is implemented to solve this system. Once the parameters are known, the stresses can be easily determined at any point in the laminate. Results are presented for through-thickness and interlaminar stress distributions for angle-ply, cross-ply (symmetric and unsymmetric laminates), and quasi-isotropic laminates subjected to uniform extension and bending. It is shown that the solution compares well with existing finite element solutions and represents an improved approximate solution for interlaminar stresses, primarily at interfaces where global equilibrium is satisfied by the in-plane stresses, but large local mismatch in properties requires the presence of interlaminar stresses.

Rose, Cheryl A.↗

Designing reduced-order linear multivariable controllers using experimentally derived plant data

An iterative numerical algorithm for simultaneously improving multiple performance and stability robustness criteria for multivariable feedback systems is developed. The unsatisfied design criteria are improved by updating the free parameters of an initial, stabilizing controller's state-space matrices. Analytical expressions for the gradients of the design criteria are employed to determine a parameter correction that improves all of the feasible, unsatisfied design criteria at each iteration. A controller design is performed using the algorithm with experimentally derived data from a large space structure test facility. Experimental results of the controller's performance at the facility are presented.

Frazier, W. G.↗

Statecharts Via Process Algebra

Statecharts is a visual language for specifying the behavior of reactive systems. The Language extends finite-state machines with concepts of hierarchy, concurrency, and priority. Despite its popularity as a design notation for embedded system, precisely defining its semantics has proved extremely challenging. In this paper, a simple process algebra, called Statecharts Process Language (SPL), is presented, which is expressive enough for encoding Statecharts in a structure-preserving and semantic preserving manner. It is establish that the behavioral relation bisimulation, when applied to SPL, preserves Statecharts semantics

Luttgen, Gerald↗

Effect of Electrical Stimulation on Beta-Adrenergic Receptor Population and Cyclic AMP Production in Chicken and Rat Skeletal Muscle Cell Cultures

Expression of the beta-adrenergic receptor (PAR) and its coupling to Adenosine 3'5' Cyclic Monophosphate (cAMP) synthesis are important components of the signaling system that controls muscle atrophy and hypertrophy and the goal of this study was to determine if electrical stimulation in a pattern simulating slow muscle contraction would alter the PAR response in primary cultures of avian and mammalian skeletal muscle cells. Specifically chicken skeletal muscle cells and rat skeletal muscle cells that had been grown for 7 d in culture, were subjected to electrical stimulation for an additional 2 d at a pulse frequency of 0.5 pulses/sec and a pulse duration of 200 msec. In chicken skeletal muscle cells, the PAR population was not significantly affected by electrical stimulation; however, the ability, of these cells to synthesize cyclic AMP was reduced by approximately one-half. In contrast, the PAR population in rat muscle cells was increased slightly but not significantly by electrical stimulation, and the ability of these cells to synthesize cyclic AMP was increased by almost twofold. The basal levels of intracellular cyclic AMP in neither rat muscle cells nor chicken muscle cells were affected by electrical stimulation.

Young, Ronald B.↗

Predicting Cost/Performance Trade-offs For Whitney: A Commodity Computing Cluster

Recent advances in low-end processor and network technology have made it possible to build a "supercomputer" out of commodity components. We develop simple models of the NAS Parallel Benchmarks version 2 (NPB 2) to explore the cost/performance trade-offs involved in building a balanced parallel computer supporting a scientific workload. By measuring single processor benchmark performance, network latency, and network bandwidth, and using closed form expressions detailing the number and size of messages sent by each benchmark, our models predict benchmark performance to within 30%. A comparison based on total system cost reveals that current commodity technology (200 MHz Pentium Pros with 100baseT Ethernet) is well balanced for the NPBs up to a total system cost of around $ 1,000,000.

Becker, Jeffrey C.↗

Drosophila Lyra mutations are gain-of-function mutations of senseless

The Lyra mutation was first described by Jerry Coyne in 1935. Lyra causes recessive pupal lethality and adult heterozygous Lyra mutants exhibit a dominant loss of the anterior and posterior wing margins. Unlike many mutations that cause loss of wing tissue (e.g., scalloped, Beadex, cut, and apterous-Xasta), Lyra wing discs do not exhibit increased necrotic or apoptotic cell death, nor do they show altered BrdU incorporation. However, during wing disc eversion, loss of the anterior and posterior wing margins is apparent. We have previously shown that senseless, a gene that is necessary and sufficient for peripheral nervous system (PNS) development, is allelic to Lyra. Here we show by several genetic criteria that Lyra alleles are neomorphic alleles of senseless that cause ectopic expression of SENSELESS in the wing pouch. Similarly, overexpression of SENSELESS in the wing disc causes loss of wing margin tissue, thereby mimicking the Lyra phenotype. Lyra mutants display aberrant expression of DELTA, VESTIGIAL, WINGLESS, and CUT. As in Lyra mutants, overexpression of SENSELESS in some areas of the wing pouch also leads to loss of WINGLESS and CUT. In summary, our data indicate that overexpression of SENSELESS causes a severe reduction in NOTCH signaling that in turn may lead to decreased transcription of several key genes required for wing development, leading to a failure in cell proliferation and loss of wing margin tissue.

Non-NASA Center↗

The cytoskeleton of Drosophila-derived Schneider line-1 and Kc23 cells undergoes significant changes during long-term culture

Insect cell cultures derived from Drosophila melanogaster are increasingly being used as an alternative system to mammalian cell cultures, as they are amenable to genetic manipulation. Although Drosophila cells are an excellent tool for the study of genes and expression of proteins, culture conditions have to be considered in the interpretation of biochemical results. Our studies indicate that significant differences occur in cytoskeletal structure during the long-term culture of the Drosophila-derived cell lines Schneider Line-1 (S1) and Kc23. Scanning, transmission-electron, and immunofluorescence microscopy studies reveal that microfilaments, microtubules, and centrosomes become increasingly different during the culture of these cells from 24 h to 7-14 days. Significant cytoskeletal changes are observed at the cell surface where actin polymerizes into microfilaments, during the elongation of long microvilli. Additionally, long protrusions develop from the cell surface; these protrusions are microtubule-based and establish contact with neighboring cells. In contrast, the microtubule network in the interior of the cells becomes disrupted after four days of culture, resulting in altered transport of mitochondria. Microtubules and centrosomes are also affected in a small percent of cells during cell division, indicating an instability of centrosomes. Thus, the cytoskeletal network of microfilaments, microtubules, and centrosomes is affected in Drosophila cells during long-term culture. This implies that gene regulation and post-translational modifications are probably different under different culture conditions.

NASA Discipline Developmental Biology↗

STS-114: Discovery Mission Status Briefing

Paul Hill, STS-114 Lead Shuttle Flight Director, talks about the imagery that was captured during the first twenty four hours in orbit. He expresses that new data was captured during ascent of the Space Shuttle Discovery through imagery and in-orbit handheld photographs of the Orbital Maneuvering system (OMS) pods were taken. Laser surveys were also taken of both the wing leading edges and nose caps using the Orbiter Boom and Sensor System (OBSS) instrument package. He presents raw footage from the Laser Dynamic Range Imager (LDRI) at the end of the OBSS showing RCC panels and tiles. He also answers questions from the news media about the possible damage to the Orbiter and debris during lift-off.

Source record↗

MISR Camera Geometry Model (MISANCGM_V2)

The CGM dataset is used to describe pointing geometry of the nine MISR cameras. It consists of a set of parameters used in a mathematical expression that gives the pointing direction of an arbitrary pixel in the spacecraft attitude frame of reference. These parameters represent the geometry of the camera system and account for distortions from an ideal optical system..

AM-1↗

In vitro Catecholamine Exposure Produces Variable Effects on the B7 Costimulatory Pathway in Human Monocytic Cells

Catecholamines have been associated with immunomodulation of the adaptive immune system towards a Th2 response in vitro. We therefore examined the role of in vitro epinephrine (EPI) and norepinephrine (NE) exposure on the B7 costimulatory expression of antigen presenting cells (APC) from human monocytic cell lines and human peripheral blood mononuclear cells (PBMC). THP1 monocytic cells and CD14+ cells from normal human PBMC were stimulated with lipopolysaccharide (LPS) and incubated with physiologic stress levels (10(exp -6) - 10(exp -8)M) of EPI or NE for 24 hours. Cells were subsequently stained with CD80 FITC, CD86 PE, and CD14 PC5 antibodies and analyzed by flow cytometry for changes in fluorescence and mean fluorescence intensity (MFI). Exposure of THP1 to EPI in vitro at concentrations of 10(exp -6), 10(exp -7) and 10(exp -8)M significantly decreased mean CD80 from 42 plus or minus 0.7% to 11 plus or minus 0.44%, 19.1 plus or minus 2.0%, and 30.7 plus or minus 2.1% expression, respectively (p less than 0.01). In addition, CD86 expression increased with EPI at 10(exp -6), 10(exp -7) and 10(exp -8) M from 9.2 plus or minus 0.52% to 41 plus or minus 3.8%, 26.4 plus or minus 1.9%, and 15.74 plus or minus 1.8% expression, respectively (p less than 0.01). Similar results for mean CD80 and CD86 percent expression were observed for CD14+ cells from PBMC with a sample size of N = 6 and for NE when substituted for EPI. The data show that in vitro exposure to catecholamines significantly decreases %CD86 expression and significantly increases %CD86 expression in THP1 cells and human CD14+ APC. Previous studies have suggested an association between increased CD86 expression and TH2 activity. Thus, these data suggest that immunomodulation by catecholamines results in part by the variable effects of the B7 costimulatory pathway in APC.

Salicru, A. N.↗

Methane on Mars: Thermodynamic Equilibrium and Photochemical Calculations

The detection of methane (CH4) in the atmosphere of Mars by Mars Express and Earth-based spectroscopy is very surprising, very puzzling, and very intriguing. On Earth, about 90% of atmospheric ozone is produced by living systems. A major question concerning methane on Mars is its origin - biological or geological. Thermodynamic equilibrium calculations indicated that methane cannot be produced by atmospheric chemical/photochemical reactions. Thermodynamic equilibrium calculations for three gases, methane, ammonia (NH3) and nitrous oxide (N2O) in the Earth s atmosphere are summarized in Table 1. The calculations indicate that these three gases should not exist in the Earth s atmosphere. Yet they do, with methane, ammonia and nitrous oxide enhanced 139, 50 and 12 orders of magnitude above their calculated thermodynamic equilibrium concentration due to the impact of life! Thermodynamic equilibrium calculations have been performed for the same three gases in the atmosphere of Mars based on the assumed composition of the Mars atmosphere shown in Table 2. The calculated thermodynamic equilibrium concentrations of the same three gases in the atmosphere of Mars is shown in Table 3. Clearly, based on thermodynamic equilibrium calculations, methane should not be present in the atmosphere of Mars, but it is in concentrations approaching 30 ppbv from three distinct regions on Mars.

Levine, J. S.↗

Using NASA's Reference Architecture: Comparing Polar and Geostationary Data Processing Systems

The JPSS and GOES-R programs are housed at NASA GSFC and jointly implemented by NASA and NOAA to NOAA requirements. NASA's role in the JPSS Ground System is to develop and deploy the system according to NOAA requirements. NASA's role in the GOES-R ground segment is to provide Systems Engineering expertise and oversight for NOAA's development and deployment of the system. NASA's Earth Science Data Systems Reference Architecture is a document developed by NASA's Earth Science Data Systems Standards Process Group that describes a NASA Earth Observing Mission Ground system as a generic abstraction. The authors work within the respective ground segment projects and are also separately contributors to the Reference Architecture document. Opinions expressed are the author's only and are not NOAA, NASA or the Ground Projects' official positions.

Ullman, Richard↗

Toward a Model-Based Approach for Flight System Fault Protection

Use SysML/UML to describe the physical structure of the system This part of the model would be shared with other teams - FS Systems Engineering, Planning & Execution, V&V, Operations, etc., in an integrated model-based engineering environment Use the UML Profile mechanism, defining Stereotypes to precisely express the concepts of the FP domain This extends the UML/SysML languages to contain our FP concepts Use UML/SysML, along with our profile, to capture FP concepts and relationships in the model Generate typical FP engineering products (the FMECA, Fault Tree, MRD, V&V Matrices)

fault protection↗

Conformal Weyl Gravity and Perihelion Precession

We investigate the perihelion shift of planetary motion in conformal Weyl gravity using the metric of the static, spherically symmetric solution discovered by Mannheim and Kazanas. To this end we employ a procedure similar to that used by Weinberg for the Schwarzschild solution, which has also been used recently to study the solar system effects of the cosmological constant Lambda. We show that besides the general relativistic terms obtained earlier from the Schwarzschild-de Sitter solution, the expression for the perihelion shift includes a negative contribution which arises from the linear term gamma ray in the metric. Using data for perihelion shift observations, we obtain constraints on the value of the constant gammma similar to that obtained earlier using galactic rotational curves.

Sultana, Joseph↗