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At least 1,747 records · Page 97

Dry heat sterilization as a method to recycle N95 respirator masks: The importance of fit

In times of crisis, including the current COVID-19 pandemic, the supply chain of filtering facepiece respirators, such as N95 respirators, are disrupted. To combat shortages of N95 respirators, many institutions were forced to decontaminate and reuse respirators. While several reports have evaluated the impact on filtration as a measurement of preservation of respirator function after decontamination, the equally important fact of maintaining proper fit to the users’ face has been understudied. In the current study, we demonstrate the complete inactivation of SARS-CoV-2 and preservation of fit test performance of N95 respirators following treatment with dry heat. We apply scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS), X-ray diffraction (XRD) measurements, Raman spectroscopy, and contact angle measurements to analyze filter material changes as a consequence of different decontamination treatments. We further compared the integrity of the respirator after autoclaving versus dry heat treatment via quantitative fit testing and found that autoclaving, but not dry heat, causes the fit of the respirator onto the users face to fail, thereby rendering the decontaminated respirator unusable. Our findings highlight the importance to account for both efficacy of disinfection and mask fit when reprocessing respirators to for clinical redeployment.

77 NANOSCIENCE AND NANOTECHNOLOGY↗

Novel method of recycling perovskite solar cells using iodide solutions

A novel recycling method utilizing aqueous iodide solutions has shown promise at selectively dissolving lead perovskite and preserving the glass substrate of lead perovskite solar cells (PSCs). Perovskite compounds are notorious for degrading upon contact with moisture into lead iodide which can be capitalized upon for recycling. When iodide ions reach a critical concentration in aqueous solutions, the solubility of lead iodide begins to rapidly increase as several complex ions are formed. Iodide solutions selectively interact with the perovskite material which dissolves from the edge inwards, allowing for exfoliation of the back contact and retention of the glass substrate and electron transport layer. PbI 2 solubility studies using KI, HI, and NH 4 I were conducted to determine an effective iodide source to develop a scalable recycling process. Further, retaining the coated glass substrate intact preserves the possibility to manufacture new solar cells from the same materials, by also omitting the use of organic solvents the costs as well as the human and environmental hazards of recycling PSCs can be minimized.

14 SOLAR ENERGY↗

Frequency Oracle for Sensitive Data Monitoring

As data privacy issues grow, finding the best privacy preservation algorithm for each situation is increasingly essential. This research has focused on understanding the frequency oracles (FO) privacy preservation algorithms. FO conduct the frequency estimation of any value in the domain. The aim is to explore how each can be best used and recommend which one to use with which data type. We experimented with different data scenarios and federated learning settings. Results showed clear guidance on when to use a specific algorithm.

Sances, Richard↗

Is Mini Beam Ready for Human Trials? Results of Randomized Study of Treating De-Novo Brain Tumors in Canines Using Linear Accelerator Generated Mini Beams

The main challenge in treating malignant brain neoplasms lies in eradicating the tumor while minimizing treatmentrelated damage. Conventional radiation treatments are associated with considerable side effects. Synchrotron generated micro-beam radiation (SMBRT) has shown to preserve brain architecture while killing tumor cells, however physical characteristics and limited facility access restrict its use. We have created a new clinical device which produces mini beams on a linear accelerator, to provide a new type of treatment called mini-beam radiation therapy (MBRT). The objective of this study is to compare the treatment outcomes of linear accelerator based MBRT versus standard radiation treatment (SRT), to evaluate the tumor response and the treatment-related changes in the normal brain with respect to each treatment type. Pet dogs with de-novo brain tumors were accrued for treatment. Dogs were randomized between standard fractionated stereotactic (9 Gy in 3 fractions) radiation treatment vs. a single fraction of MBRT (26 Gy mean dose). Dogs were monitored after treatment for clinical assessment and imaging. When the dogs were euthanized, a veterinary pathologist assessed the radiation changes and tumor response. We accrued 16 dogs, 8 dogs in each treatment arm. In the MBRT arm, 71% dogs achieved complete pathological remission. The radiation-related changes were all confined to the target region. Structural damage was not observed in the beam path outside of the target region. In contrast, none of the dogs in control group achieved remission and the treatment related damage was more extensive. Therapeutic superiority was observed with MBRT, including both tumor control and the normal structural preservation. The MBRT findings are suggestive of an immune related mechanism which is absent in standard treatment. These findings together with the widespread availability of clinical linear accelerators make MBRT a promising research topic to explore further treatment and clinical trial opportunities.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

DEM simulation of the compression of crushable sand: does the initial particle shape matter?

Advances in DEM modeling, combined with high-resolution X-ray tomography, opened the way for computer models based on virtual replicas of the particles which preserve nearly all facets of their geometry. This leads to simulation advantages, but also high computational costs. Here we tackle a question stemming from this trend: how accurate should particle models be to ensure accuracy? We address this question for the case of the compression of crushable sand. LS-DEM was used to generate three models of Ottawa sand (exact replicas, ellipsoids, and spheres) from digital images of its grains. Compression-induced crushing was simulated for all sets by tracking evolving size and shape distribution. The results confirm that exact replicas provide the closest match of the measurements. However, intermediate degrees of rendering (e.g. ellipsoids preserving volume and aspect ratio of the real grains) led to satisfactory results only marginally different from those of exact replicas. In conclusion, these findings provide an example of the protocols that may be followed to identify the optimal degree of particle approximation which should be regarded as mandatory to achieve a conscious, sustainable use of computational resources.

58 GEOSCIENCES↗

Denoising Seismic Waveforms Using a Wavelet-Transform-Based Machine-Learning Method

Seismic waveform data recorded at stations can be thought of as a superposition of the signal from a source of interest and noise from other sources. Frequency‐based filtering methods for waveform denoising do not result in desired outcomes when the targeted signal and noise occupy similar frequency bands. Recently, denoising techniques based on deep‐learning convolutional neural networks (CNNs), in which a recorded waveform is decomposed into signal and noise components, have led to improved results. These CNN methods, which use short‐time Fourier transform representations of the time series, provide signal and noise masks for the input waveform. These masks are used to create denoised signal and designaled noise waveforms, respectively. However, advancements in the field of image denoising have shown the benefits of incorporating discrete wavelet transforms (DWTs) into CNN architectures to create multilevel wavelet CNN (MWCNN) models. The MWCNN model preserves the details of the input due to the good time–frequency localization of the DWT. In this report we use a data set of over 382,000 constructed seismograms recorded by the University of Utah Seismograph Stations network to compare the performance of CNN and MWCNN‐based denoising models. Evaluation of both models on constructed test data shows that the MWCNN model outperforms the CNN model in the ability to recover the ground‐truth signal component in terms of both waveform similarity and preservation of amplitude information. Model evaluation of real‐world data shows that both the CNN and MWCNN models outperform standard band‐pass filtering (BPF; average improvement in signal‐to‐noise ratio of 9.6 and 19.7 dB, respectively, with respect to BPF). Evaluation of continuous data suggests the MWCNN denoiser can improve both signal detection capabilities and phase arrival time estimates.

58 GEOSCIENCES↗

Optimization of a High Bunch Charge ERL Injection Merger for PERLE

Delivery of high charge electron bunches into the main loop of an ERL (energy recovery linac) while preserving the emittance is challenging. This is because at the typical injection momentum, space charge forces still have a significant effect on the beam dynamics. In this work we consider the design of the merger for PERLE, an ERL test facility to be based at IJCLab in France. Previous simulations have shown that the baseline DC gun based injector can achieve the required emittance at the booster linac exit. The quality of the 500 pC bunches must then be preserved with space charge through the merger at total beam energy of 7 MeV keeping the emittance below 6 mm mrad. The beam dynamics in the merger were simulated using the code OPAL and optimised using a genetic algorithm. Three possible merger schemes were investigated. The goal of the optimisation was to minimise the emittance growth while also achieving the required Twiss parameters to match onto the spreader at the main linac exit. A three dipole solution is then examined in more detail.

Hounsell, B.↗

Simulation of Transparent Spin Experiment in RHIC

The transparent spin mode has been proposed as a new technique for preservation and control of the spin polarization of an ion beam in a synchrotron. The ion rings of the proposed Jefferson Lab Electron-Ion Collider adopted this technique in their figure-8 design. The transparent spin mode can also be setup in a racetrack with two identical Siberian snakes. There is a proposal to test the predicted features of the spin transparent mode in RHIC, which already has all of the necessary hardware capabilities. We have earlier analytically estimated the setup parameters and developed a preliminary experimental plan. In this paper we describe simulations of the proposed experiment using a Zgoubi model of RHIC. We present simulation of the polarization preservation during acceleration in the transparent spin mode. We also demonstrate polarization control by simulating an adiabatic polarization adjustment. A procedure to measure the strength of the spin transparent resonance is illustrated.

Morozov, Vasiliy↗

Multiple interaction points in ghost collisions

The Ghost Collider makes use of unique “ghost” bunches, which are electrically neutral combinations of electrons and positrons within the same RF bucket, eliminates the beam-beam effects typically present at the interaction point (IP) in conventional colliders. This allows for the novel possibility of placing multiple interaction regions in series, achieving additive luminosity without introducing significant disruption. However, to get higher luminosity, the beta functions at the IP reaches millimeter scale, which in turn adds significant chromatic contribution to the collider. Correcting these chromatic effects is essential to maintain beam stability and ensure high luminosity during collider operation. By carefully adjusting the phase advance between two IRs that are placed in series, it becomes possible to cancel chromaticity globally, enabling stable collider operation while preserving high luminosity. In this paper we discuss the design of such IR/IRs to be used in a ghost collider.

Accelerator Physics↗

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

DDX3X encodes a DEAD-box family RNA helicase (DDX3) commonly mutated in medulloblastoma, a highly aggressive cerebellar tumor affecting both children and adults. Despite being implicated in several facets of RNA metabolism, the nature and scope of DDX3's interactions with RNA remain unclear. Here, we show DDX3 collaborates extensively with the translation initiation machinery through direct binding to 5'UTRs of nearly all coding RNAs, specific sites on the 18S rRNA, and multiple components of the translation initiation complex. Impairment of translation initiation is also evident in primary medulloblastomas harboring mutations in DDX3X, further highlighting DDX3's role in this process. Arsenite-induced stress shifts DDX3 binding from the 5'UTR into the coding region of mRNAs concomitant with a general reduction of translation, and both the shift of DDX3 on mRNA and decreased translation are blunted by expression of a catalytically-impaired, medulloblastoma-associated DDX3R534H variant. Furthermore, despite the global repression of translation induced by arsenite, translation is preserved on select genes involved in chromatin organization in DDX3R534H-expressing cells. Thus, DDX3 interacts extensively with RNA and ribosomal machinery to help remodel the translation landscape in response to stress, while cancer-related DDX3 variants adapt this response to selectively preserve translation.

60 APPLIED LIFE SCIENCES↗

XMark: Reliable Multi-Bit Watermarking for LLM-Generated Texts

Multi-bit watermarking has emerged as a promising solution for embedding imperceptible binary messages into Large Language Model (LLM)-generated text, enabling reliable attribution and tracing of malicious usage of LLMs. Despite recent progress, existing methods still face key limitations: some become computationally infeasible for large messages, while others suffer from a poor trade-off between text quality and decoding accuracy. Moreover, the decoding accuracy of existing methods drops significantly when the number of tokens in the generated text is limited, a condition that frequently arises in practical usage. To address these challenges, we propose XMark, a novel method for encoding and decoding binary messages in LLM-generated texts. The unique design of XMark’s encoder produces a less distorted logit distribution for watermarked token generation, preserving text quality, and also enables its tailored decoder to reliably recover the encoded message with limited tokens. Extensive experiments across diverse downstream tasks show that XMark significantly improves decoding accuracy while preserving the quality of watermarked text, outperforming prior methods. The code will be made publicly available upon acceptance.

Xu, Jiahao [University of Nevada, Reno]↗

Microhydrological Niches in Soils: How Mucilage and EPS Alter the Biophysical Properties of the Rhizosphere and Other Biological Hotspots

Core Ideas Plant mucilage and bacterial extracellular polymeric substances (EPS) prevent the breakup of the soil liquid phase. Formation of continuous structures buffers soil hydraulic properties. The release of viscous polymeric substances represents a universal strategy. Plant roots and bacteria are capable of buffering erratic fluctuations of water content in their local soil environment by releasing a diverse, highly polymeric blend of substances (e.g. extracellular polymeric substances [EPS] and mucilage). Although this concept is well accepted, the physical mechanisms by which EPS and mucilage interact with the soil matrix and determine the soil water dynamics remain unclear. High‐resolution X‐ray computed tomography revealed that upon drying in porous media, mucilage (from maize [ Zea mays L.] roots) and EPS (from intact biocrusts) form filaments and two‐dimensional interconnected structures spanning across multiple pores. Unlike water, these mucilage and EPS structures connecting soil particles did not break up upon drying, which is explained by the high viscosity and low surface tension of EPS and mucilage. Measurements of water retention and evaporation with soils mixed with seed mucilage show how these one‐ and two‐dimensional pore‐scale structures affect macroscopic hydraulic properties (i.e., they enhance water retention, preserve the continuity of the liquid phase in drying soils, and decrease vapor diffusivity and local drying rates). In conclusion, we propose that the release of viscous polymeric substances and the consequent creation of a network bridging the soil pore space represent a universal strategy of plants and bacteria to engineer their own soil microhydrological niches where stable conditions for life are preserved.

Benard, Pascal↗

Lieb-Schultz-Mattis anomalies as obstructions to gauging (non-on-site) symmetries

We study ’t Hooft anomalies of global symmetries in 1+1d lattice Hamiltonian systems. We consider anomalies in internal and lattice translation symmetries. We derive a microscopic formula for the “anomaly cocycle” using topological defects implementing twisted boundary conditions. The anomaly takes value in the cohomology group H^3(G,U(1)) × H^2(G,U(1)) H 3 ( G , U ( 1 ) ) × H 2 ( G , U ( 1 ) ) . The first factor captures the anomaly in the internal symmetry group G, and the second factor corresponds to a generalized Lieb-Schultz-Mattis anomaly involving G and lattice translation. We present a systematic procedure to gauge internal symmetries (that may not act on-site) on the lattice. We show that the anomaly cocycle is the obstruction to gauging the internal symmetry while preserving the lattice translation symmetry. As an application, we construct anomaly-free chiral lattice gauge theories. We demonstrate a one-to-one correspondence between (locality-preserving) symmetry operators and topological defects, which is essential for the results we prove. We also discuss the generalization to fermionic theories. Finally, we construct non-invertible lattice translation symmetries by gauging internal symmetries with a Lieb-Schultz-Mattis anomaly.

Physics↗

Candidate phases for SU(2) adjoint QCD$_4$ with two flavors from $\mathcal{N}=2$ supersymmetric Yang-Mills theory

We study four-dimensional adjoint QCD with gauge group SU(2) and two Weyl fermion flavors, which has an SU(2) R chiral symmetry. The infrared behavior of this theory is not firmly established. We explore candidate infrared phases by embedding adjoint QCD into N = 2 supersymmetric Yang-Mills theory deformed by a supersymmetry-breaking scalar mass M that preserves all global symmetries and 't Hooft anomalies. This includes 't Hooft anomalies that are only visible when the theory is placed on manifolds that do not admit a spin structure. The consistency of this procedure is guaranteed by a nonabelian spin-charge relation involving the SU(2) R symmetry that is familiar from topologically twisted N = 2 theories. Since every vacuum on the Coulomb branch of the N = 2 theory necessarily matches all 't Hooft anomalies, we can generate candidate phases for adjoint QCD by deforming the theories in these vacua while preserving all symmetries and 't Hooft anomalies. One such deformation is the supersymmetry-breaking scalar mass M itself, which can be reliably analyzed when M is small. In this regime it gives rise to an exotic Coulomb phase without chiral symmetry breaking. By contrast, the theory near the monopole and dyon points can be deformed to realize a candidate phase with monopole-induced confinement and chiral symmetry breaking. The low-energy theory consists of two copies of a CP 1 sigma model, which we analyze in detail. Certain topological couplings that are likely to be present in this CP 1 model turn the confining solitonic string of the model into a topological insulator. We also examine the behavior of various candidate phases under fermion mass deformations. We speculate on the possible large-M behavior of the deformed N = 2 theory and conjecture that the CP 1 phase eventually becomes dominant.

Córdova, Clay↗

Higgs-confinement transitions in QCD from symmetry protected topological phases

In gauge theories with fundamental matter there is typically no sharp way to distinguish confining and Higgs regimes, e.g. using generalized global symmetries acting on loop order parameters. It is standard lore that these two regimes are continuously connected, as has been explicitly demonstrated in certain lattice and continuum models. We point out that Higgsing and confinement sometimes lead to distinct symmetry protected topological (SPT) phases -- necessarily separated by a phase transition -- for ordinary global symmetries. We present explicit examples in 3+1 dimensions, obtained by adding elementary Higgs fields and Yukawa couplings to QCD while preserving parity P and time reversal T. In a suitable scheme, the confining phases of these theories are trivial SPTs, while their Higgs phases are characterized by non-trivial P- and T-invariant theta-angles θ f , θ g = π for flavor or gravity background gauge fields, i.e. they are topological insulators or superconductors. Finally, we consider conventional three-flavor QCD (without elementary Higgs fields) at finite U(1) B baryon-number chemical potential μ B , which preserves P and T. At very large μ B , three-flavor QCD is known to be a completely Higgsed color superconductor that also spontaneously breaks U(1) B . We argue that this high-density phase is in fact a gapless SPT, with a gravitational theta-angle θ g = π that safely co-exists with the U(1) B Nambu-Goldstone boson. We explain why this SPT motivates unexpected transitions in the QCD phase diagram, as well as anomalous surface modes at the boundary of quark-matter cores inside neutron stars.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Assessing the Feasibility of Renewable Energy Development and Energy Efficiency Deployment on Tribal Lands

The Keweenaw Bay Indian Community (KBIC) is committed to preserving our natural environment and reducing the amount of fossil fuels consumed while developing "green" business manufacturing jobs on tribal lands. The Tribe's Comprehensive Strategic Plan seeks to diversify the Tribal Economy through the creation of alternative energy businesses, such as wind, solar and bio-mass facilities while protecting the waters of Lake Superior, tribal inland lakes and streams. In addition, the Community desired to utilize clean/green energy resources to promote the self-sufficiency of the Tribal Nation. The objective of the study is to preserve our environment and maintain our cultural goals of using the resources of the land wisely. To reduce our consumption of fossil fuels, mercury and carbon dioxide emissions, which harm our water and land; we have decided to evaluate the opportunities of utilizing wind power. Preliminary projections show that we may eliminate pollution from our land in a cost effective manner. This study will evaluate wind capacity and our current energy consumption while projecting the feasibility of converting to wind power for operations at our major facilities. This project will study the feasibility of wind power at two locations for the purpose of reducing the Tribe's reliance upon fossil fuels and creating business opportunities, jobs and revenue for the community.

17 WIND ENERGY↗

Release of Continuous Representation for S(α,β) ACE Data

For low energy neutrons, the default free gas model for scattering cross sections is not always appropriate. Molecular effects or crystalline structure effects can affect the neutron scattering cross sections. These effects are included in the S(α; β) thermal neutron scattering data and are tabulated in file 7 of the ENDF6 format files. S stands for scattering. α is a momentum transfer variable and is an energy transfer variable. The S(α; β) cross sections can include coherent elastic scattering (no E change for the neutron, but specific scattering angles), incoherent elastic scattering (no E change for the neutron, but continuous scattering angles), and inelastic scattering (E change for the neutron, and change in angle as well). Every S(α; β) material will have inelastic scattering and may have either coherent or incoherent elastic scattering (but not both). Coherent elastic scattering cross sections have distinctive jagged-looking Bragg edges, whereas the other cross sections are much smoother. The evaluated files from the NNDC are processed locally in the THERMR module of NJOY. Data can be produced either for continuous energy Monte Carlo codes (using ACER) or embedded in multi-group cross sections for deterministic (or even multi-group Monte Carlo) codes (using GROUPR). Currently, the S(α; β) files available for MCNP use discrete energy changes for inelastic scattering. That is, the scattered neutrons can only be emitted at specific energies— rather than across a continuous spectrum of energies. The discrete energies are chosen to preserve the average secondary neutron energy, i.e., in an integral sense, but the discrete treatment does not preserve any differential quantities in energy or angle.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Geochronology and Geomorphology of the Pioneer Archaeological Site (10BT676), Upper Snake River Plain, Idaho

The Pioneer site in southeastern Idaho, an open-air, stratified, multi-component archaeological locality on the upper Snake River Plain, provides an ideal situation for understanding the geomorphic history of the Big Lost River drainage system. We conducted a block excavation with the goal of understanding the geochronological context of both cultural and geomorphological components at the site. The results of this study show a sequence of five soil formation episodes forming three terraces beginning prior to 7200 cal yr BP and lasting until the historic period, preserving one cultural component dated to ~3800 cal yr BP and multiple components dating to the last 800 cal yr BP. In addition, periods of deposition and stability at Pioneer indicate climate fluctuation during the middle Holocene (~7200-3800 cal yr BP), minimal deposition during the late Holocene, and a period of increased deposition potentially linked to the Little Ice Age. In addition, evidence for a high-energy erosion event dated to ~3800 cal yr BP suggest a catastrophic flood event during the middle Holocene that may correlate with volcanic activity at the Craters of the Moon lava fields to the northwest. This study provides a model for the study of alluvial terrace formations in arid environments and their potential to preserve stratified archaeological deposits.

54 ENVIRONMENTAL SCIENCES↗