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At least 1,729 records · Page 96

Production of hydroxylated fatty acids in genetically modified plants

This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described.

59 BASIC BIOLOGICAL SCIENCES↗

Genetically Enhanced Sorghum and Sugarcane: Engineering Hydrocarbon Biosynthesis and Storage together with Increased Photosynthetic Efficiency into the Saccharinae

PETRO Project: UIUC is working to convert sugarcane and sorghum—already 2 of the most productive crops in the world—into dedicated bio-oil crop systems. Three components will be engineered to produce new crops that have a 50% higher yield, produce easily extractable oils, and have a wider growing range across the U.S. This will be achieved by modifying the crop canopy to better distribute sunlight and increase its cold tolerance. By directly producing oil in the shoots of these plants, these biofuels could be easily extracted with the conventional crushing techniques used today to extract sugar.

Advanced Fuels↗

Genetically encoded fluorescent coumarin amino acids

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the coumarin unnatural amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine and related translation systems.

59 BASIC BIOLOGICAL SCIENCES↗

Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetase that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel sythetases molecules, methods for identifying and making the novel synthetases, methods for producing containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lapidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.

59 BASIC BIOLOGICAL SCIENCES↗

Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli . The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel synthetase molecules, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lipidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗