Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “sensitivity study”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,711 records · Page 95

CMS HGCAL ECON-D ASIC : Impact of CMOS fabrication process tuning on performance and radiation tolerance

The CMS experiment’s High Granularity Calorimeter (HGCAL) upgrade will replace CMS’s existing endcap calorimeters in preparation for the High Luminosity LHC. To effectively use over 6 million channels of this “imaging”calorimeter, CMS has developed two novel Endcap Concentrator (ECON) ASICs to perform data compression/selection on detector. The ECON-D ASIC operates on the 750kHz data path, and the ECON-T ASIC on the 40MHz trigger path. These 65 nm CMOS ASICs are radiation tolerant to 200 Mrad and low power, operating at less than 2.5 mW/channel. The first full-functionality prototype ECONs were produced and characterized in 2021-23, and an initial engineering run was performed in 2024. ECON-D radiation testing for the engineering run revealed that the chip’s internal SRAMs produce intermittent read errors for a non-negligible fraction of chips. Further investigation indicated that the SRAM performance is highly sensitive to the exact parameters of the CMOS fabrication process. To both study this process sensitivity and mitigate SRAM performance issues, twenty ECON wafers were produced in 2025 with a range of doping concentrations designed to tune the underlying transistor threshold voltage by 0%, 5%, 10%, and 15% from nominal. This talk will present first measurements of ECON-D performance, power consumption, and radiation tolerance for these four variations of CMOS process.

Syal, Chinar [Fermilab]↗

Microscale Thermophoresis (MST) as a Tool to Study Binding Interactions of Oxygen-Sensitive Biohybrids

Microscale thermophoresis (MST) is a technique used to measure the strength of molecular interactions. MST is a thermophoretic-based technique that monitors the change in fluorescence associated with the movement of fluorescent-labeled molecules in response to a temperature gradient triggered by an IR LASER. MST has advantages over other approaches for examining molecular interactions, such as isothermal titration calorimetry, nuclear magnetic resonance, biolayer interferometry, and surface plasmon resonance, requiring a small sample size that does not need to be immobilized and a high-sensitivity fluorescence detection. In addition, since the approach involves the loading of samples into capillaries that can be easily sealed, it can be adapted to analyze oxygen-sensitive samples. In this Bio-protocol, we describe the troubleshooting and optimization we have done to enable the use of MST to examine protein–protein interactions, protein–ligand interactions, and protein–nanocrystal interactions. The salient elements in the developed procedures include 1) loading and sealing capabilities in an anaerobic chamber for analysis using a NanoTemper MST located on the benchtop in air, 2) identification of the optimal reducing agents compatible with data acquisition with effective protection against trace oxygen, and 3) the optimization of data acquisition and analysis procedures. The procedures lay the groundwork to define the determinants of molecular interactions in these technically demanding systems.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

High-Throughput Large-Scale Targeted Proteomics Assays for Quantifying Pathway Proteins in Pseudomonas putida KT2440

Targeted proteomics is a mass spectrometry-based protein quantification technique with high sensitivity, accuracy, and reproducibility. As a key component in the multi-omics toolbox of systems biology, targeted liquid chromatography-selected reaction monitoring (LC-SRM) measurements are critical for enzyme and pathway identification and design in metabolic engineering. To fulfill the increasing need for analyzing large sample sets with faster turnaround time in systems biology, high-throughput LC-SRM is greatly needed. Even though nanoflow LC-SRM has better sensitivity, it lacks the speed offered by microflow LC-SRM. Recent advancements in mass spectrometry instrumentation significantly enhance the scan speed and sensitivity of LC-SRM, thereby creating opportunities for applying the high speed of microflow LC-SRM without losing peptide multiplexing power or sacrificing sensitivity. Here, we studied the performance of microflow LC-SRM relative to nanoflow LC-SRM by monitoring 339 peptides representing 132 enzymes in Pseudomonas putida KT2440 grown on various carbon sources. The results from the two LC-SRM platforms are highly correlated. In addition, the response curve study of 248 peptides demonstrates that microflow LC-SRM has comparable sensitivity for the majority of detected peptides and better mass spectrometry signal and chromatography stability than nanoflow LC-SRM.

59 BASIC BIOLOGICAL SCIENCES↗

The use of variograms in remote sensing. I - Scene models and simulated images. II - Real digital images

Theoretical and empirical studies of variograms are presented. The sensitivity of variograms is studied through varyig parameters of scene models both in calculating explicit variograms and in simulating images. It is found that the heights of variograms are related to the proportion of an area covered by objects. It is shown that the range of influence of a variogram is related to the size of the objects in the scene and that the shape of the variogram becomes more rounded as the variance in the size distribution of objects increases. In the second part, empirically calculated variograms from real digital images are used to demonstrate these theoretical findings. These calculated variograms also show the periodicity in ground scenes and reveal anisotropy.

Woodcock, Curtis E.↗

Study of factors determining the radiation sensitivity of quartz crystal oscillators (AO189)

Quartz resonators fabricated from two different grades of quartz material and selected for their susceptibility to radiation damage as determined by transmission electron microscopy (TEM), were tested prior to the LDEF flight. These resonators were then flown on the LDEF mission where they were exposed to the radiation environment of low Earth orbit. Post-flight tests were then conducted to determine any differences in resonator performance caused by the space exposure. Results of the TEM analysis of the quartz material and preflight and postflight measurements of the flight resonators and of the space and ground based control resonators are presented. Further planned work on the TEM analysis of the quartz materials will also be outlined.

Ahearn, J. S.↗

Study of factors determining the radiation sensitivity of quartz crystal oscillators (A0189)

Previous postflight tests of quartz resonators fabricated from swept premium Q quartz were affected by the space radiation environment experienced on the Long Duration Exposure Facility (LDEF) flight. Resonators fabricated from natural quartz materials were not. The resonant frequency of the swept premium Q material exposed to the space radiation exhibited a change in frequency that was significantly larger than that of the controls or the natural crystal material and the frequency change was attributed to a recovery of damage to the quartz material sustained during the LDEF flight. Further tests of the resonators, currently in progress, are being conducted to verify this conclusion, the results of which will be presented at the LDEF Symposium.

Ahearn, J. S.↗

Experimental Study of Unshrouded Impeller Pump Stage Sensitivity to Tip Clearance

This viewgraph presentation provides information on an experiment. Its objective is to experimentally determine unshrouded impeller performance sensitivity to tip clearance. The experiment included: Determining impeller efficiency at scaled operating conditions in water at MSFC's Pump Test Equipment (PTE) Facility; Testing unshrouded impeller at three different tip clearances; Testing each tip clearance configuration at on- and off-design conditions, and collecting unsteady- and steady-state data in each configuration; Determining impeller efficiency directly using drive line torquemeter and pump inlet and exit total pressure measurements.

Williams, Robert W.↗

A Study in HRT Resolution: Seeking Maximum Sensitivity Among Variations in Sensing Element Material

The EXACT (Experiments Along Coexistence near Tricriticality) project endeavors to perform the most rigorous test to date of Renormalization Group theory. In most cases, the theory gives only approximate solutions, but it offers exact predictions in the case of the He-3-He-4 tricritical point. Currently, the project is focused on maximizing the performance of the low-temperature system's HRT (high resolution thermometer) near the tricritical point. The HRT uses a PdMn sensing element, the qualities of which change based on its Mn concentration and whether or not it is annealed. All sensing element combinations will be catalogued, and through the data, the optimum configuration will be reported.

Morales, Jeremy M.↗

Photodissociation of OCS: Deviations between theory and experiment, and the importance of higher order correlation effects

The photodissociation of carbonyl sulfide (OCS) was investigated theoretically in a series of studies by Schmidt and co-workers. Initial studies [J. A. Schmidt, M. S. Johnson, G. C. McBane, and R. Schinke, J. Chem. Phys. 136, 131101 (2012); J. A. Schmidt, M. S. Johnson, G. C. McBane, and R. Schinke, J. Chem. Phys. 137, 054313 (2012)] found photodissociation in the first UV-band to occur mainly by excitation of the 2{sup 1}A{sup ′} (A) excited state. However, in a later study [G. C. McBane, J. A. Schmidt, M. S. Johnson, and R. Schinke, J. Chem. Phys. 138, 094314 (2013)] it was found that a significant fraction of photodissociation must occur by excitation of 1{sup 1}A{sup ″} (B) excited state to explain the product angular distribution. The branching between excitation of the A and B excited states is determined by the magnitude of the transition dipole moment vectors in the Franck-Condon region. This study examines the sensitivity of these quantities to changes in the employed electronic structure methodology. This study benchmarks the methodology employed in previous studies against highly correlated electronic structure methods (CC3 and MRAQCC) and provide evidence in support of the picture of the OCS photodissociation process presented in [G. C. McBane, J. A. Schmidt, M. S. Johnson, and R. Schinke, J. Chem. Phys. 138, 094314 (2013)] showing that excitation of A and B electronic states both contribute significantly to the first UV absorption band of OCS. In addition, this study presents evidence in support of the assertion that the A state potential energy surface employed in previous studies underestimates the energy at highly bent geometries (γ ∼ 70°) leading to overestimated rotational energy in the product CO.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

New experimental approaches to search for neutrino mass

In order to obtain high sensitivity in the study of the neutrino mass it is necessary to design experiments able to optimize all the sensitivity parameters. One of the most promising techniques to achieve this goal is the bolometric technique because of its intrinsic characteristics: high detection efficiency, excellent energy resolution, low intrinsic background and the possibility to study many different compounds. The bolometric technique has already obtained excellent results on the neutrino mass study with Cuoricino. The Cuoricino experiment has also shown that surface contaminations of materials facing the detectors would be the limiting factor for the sensitivity of next generation experiments with bolometers. Mainly for this reason scintillating bolometers have been developed allowing a very efficient discrimination of alpha particles thanks to their double readout. Tests performed on these crystals showed moreover the possibility to discriminate the interacting particles through a pulse shape analysis. This feature is very promising because it allows to reach the same results on the background reduction obtained with the hybrid detectors but without complicating the experimental assembly.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Preliminary analysis of the sensitivity of AIRSAR images to soil moisture variations

Synthetic Aperture Radar (SAR) images acquired from various sources such as Shuttle Imaging Radar B (SIR-B) and airborne SAR (AIRSAR) have been analyzed for signatures of soil moisture. The SIR-B measurements have shown a strong correlation between measurements of surface soil moisture (0-5 cm) and the radar backscattering coefficient sigma(sup o). The AIRSAR measurements, however, indicated a lower sensitivity. In this study, an attempt has been made to investigate the causes for this reduced sensitivity.

Pardipuram, Rajan↗

Constraining the Global, Cloud-Free Reflected Solar Radiation Flux (RSRF) with Earth Observing System (EOS) Instruments

Variations in the top-of-atmosphere reflected solar radiation flux, and in the factors that determine its value, are among the most important diagnostic indicators of changes in Earth's energy balance. Data from the MISR (Multi-angle Imaging SpectroRadiometer), MODIS (Moderate-resolution Imaging Spectroradiometer), SAGE-3 (Stratospheric Aerosol and Gas Experiment), and CERES (Clouds and Earth's Radiant Energy System), all of which are spacecraft instruments scheduled for launch in 1999, will each constrain pieces of the RSRF budget. Prior to launch, we are performing studies to determine the sensitivity of these instruments to key factors that influence the cloud-free RSRF: aerosol optical depth, aerosol scattering properties, and surface visible bidirectional reflectance distribution function (BRDF). We are also assessing the ability of the aggregate of instruments to constrain the overall RSRF budget under natural conditions over the globe. Consider the MISR retrieval of aerosols: according to simulations over cloud-free, calm ocean, for pure particles with natural ranges of optical depth, particle size, and indices of refraction, MISR can retrieve column aerosol optical depth for all but the darkest particles, to an uncertainty of at most 0.05 or 20%, whichever is larger, even if the particle properties are poorly known. For one common particle type, soot, constraints on the optical depth over dark ocean are very poor. The simulated measurements also allow us to distinguish spherical from non-spherical particles, to separate two to four compositional groups based on indices of refraction, and to identify three to four distinct size groups between 0. 1 and 2.0 microns characteristic radius at most latitudes. Based on these results, we expect to distinguish air masses containing different aerosol types, routinely and globally, with multiangle remote sensing data. Such results far exceed current satellite aerosol retrieval capabilities, which provide only total optical depth for assumed particle properties; the new information will complement in situ data, which give details about aerosol size and composition locally. In addition, our team is using climatologies that reflect the constraints each instrument is expected to provide, along with ERBE (Earth Radiation Budget Experiment) data and a radiative transfer code, to study overall sensitivity to RSRF, helping us prepare for similar studies with new data from the EOS-era instruments.

Kahn, Ralph↗

Sensitivity of the coefficients of thermal expansion of selected graphite reinforced composite laminates to lamina thermoelastic properties

An analytical study of the sensitivity of the laminate coefficient of thermal expansion, CTE, to changes in lamina elastic properties has been made. High modulus graphite/epoxy (P75/934, P100/934, P120/934), graphite/aluminum (P100/Al), and graphite/glass (HMS/Gl) composite materials were considered in quasi-isotropic, low thermal stress, and 'near-zero' thermal expansion laminate configurations. The effects of a positive or negative 10 percent change in lamina properties on laminate CTE is strongly dependent upon both the composite material and the laminate configuration. A 10 percent change in all of the lamina properties had very little effect on the laminate CTE of the HMS/Gl composite laminates investigated. The sensitivity and direction of change in the laminate CTE of Gr/934 depended very strongly on the fiber properties. A 10 percent change in the lamina transverse CTE resulted in changes as large as 0.216 ppm/C in the laminate CTE of a quasi-isotropic Gr/934 laminate. No significant difference was observed in the sensitivity of the laminate CTE of the P100/934 and P120/934 composite materials due to changes in lamina properties. Large changes in laminate CTE can result from measured temperature and radiation effects on lamina properties.

Tompkins, S. S.↗

Sensitivity of CONUS Summer Rainfall to the Selection of Cumulus Parameterization Schemes in NU-WRF Seasonal Simulations

This study investigates the sensitivity of daily rainfall rates in regional seasonal simulations over the contiguous United States (CONUS) to different cumulus parameterization schemes. Daily rainfall fields were simulated at 24-km resolution using the NASA-Unified Weather Research and Forecasting (NU-WRF) Model for June-August 2000. Four cumulus parameterization schemes and two options for shallow cumulus components in a specific scheme were tested. The spread in the domain-mean rainfall rates across the parameterization schemes was generally consistent between the entire CONUS and most subregions. The selection of the shallow cumulus component in a specific scheme had more impact than that of the four cumulus parameterization schemes. Regional variability in the performance of each scheme was assessed by calculating optimally weighted ensembles that minimize full root-mean-square errors against reference datasets. The spatial pattern of the seasonally averaged rainfall was insensitive to the selection of cumulus parameterization over mountainous regions because of the topographical pattern constraint, so that the simulation errors were mostly attributed to the overall bias there. In contrast, the spatial patterns over the Great Plains regions as well as the temporal variation over most parts of the CONUS were relatively sensitive to cumulus parameterization selection. Overall, adopting a single simulation result was preferable to generating a better ensemble for the seasonally averaged daily rainfall simulation, as long as their overall biases had the same positive or negative sign. However, an ensemble of multiple simulation results was more effective in reducing errors in the case of also considering temporal variation.

Iguchi, Takamichi↗