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At least 1,675 records · Page 93

Flow cytometry analysis of hormone receptors on human peripheral blood mononuclear cells to identify stress-induced neuroendocrine effects

Understanding the role of circulating peptide hormones in the pathogenesis of space-flight induced disorders would be greatly facilitated by a method which monitors chronic levels of hormones and their effects upon in vivo cell physiology. Single and simultaneous multiparameter flow cytometry analysis was employed to identify subpopulations of mononuclear cells bearing receptors for ACTH, Endorphin, and Somatomedin-C using monoclonal antibodies and monospecific antisera with indirect immunofluorescence. Blood samples were obtained from normal donors and subjects participating in decompression chamber studies (acute stress), medical student academic examination (chronic stress), and a drug study (Dexamethasone). Preliminary results indicate most ACTH and Endorphin receptor positive cells are monocytes and B-cells, exhibit little diurnal variation but the relative percentages of receptor positive cells are influenced by exposure to various stressors and ACTH inhibition. This study demonstrates the capability of flow cytometry analysis to study cell surface hormone receptor regulation which should allow insight into neuroendocrine modulation of the immune and other cellular systems during exposure to stress or microgravity.

Meehan, R. T.↗

Finite element analysis of residual stress in plasma-sprayed ceramic

Residual stress in a ZrO2-Y2O3 ceramic coating resulting from the plasma spraying operation is calculated. The calculations were done using the finite element method. Both thermal and mechanical analysis were performed. The resulting residual stress field was compared to the measurements obtained by Hendricks and McDonald. Reasonable agreement between the predicted and measured moment occurred. However, the resulting stress field is not in pure bending.

Mullen, R. L.↗

Low-velocity impact response of laminated beams subjected to initial stresses

Finite element procedures are used in conjunction with a numerical algorithm to compute the impact response of a graphite-epoxy laminated beam subjected to tensile initial stresses. The effect of initial stresses on the contact duration, impact force, coefficient of restitution, and bending and shear stresses are discussed. The analytically computed contact force history and strain response are compared with some experimental results.

Sankar, B. V.↗

Residual stresses of thin, short rectangular plates

The analysis of the residual stresses in thin, short rectangular plates is presented. The analysis is used in conjunction with a shadow moire interferometry technique by which residual stresses are obtained over a large spatial area from a strain measurement. The technique and analysis are applied to a residual stress measurement of polycrystalline silicon sheet grown by the edge-defined film growth technique.

Andonian, A. T.↗

Finite elements based on consistently assumed stresses and displacements

Finite element stiffness matrices are derived using an extended Hellinger-Reissner principle in which internal displacements are added to serve as Lagrange multipliers to introduce the equilibrium constraint in each element. In a consistent formulation the assumed stresses are initially unconstrained and complete polynomials and the total displacements are also complete such that the corresponding strains are complete in the same order as the stresses. Several examples indicate that resulting properties for elements constructed by this consistent formulation are ideal and are less sensitive to distortions of element geometries. The method has been used to find the optimal stress terms for plane elements, 3-D solids, axisymmetric solids, and plate bending elements.

Pian, T. H. H.↗

The evolution of impact basins - Cooling, subsidence, and thermal stress

The present study is concerned with an assessment of the contribution of thermal contraction and thermal stress to the topography and tectonics of large lunar impact basins. Exploratory models are developed, giving attention to the temperature structure following basin formation, the subsequent cooling of the basin region, and the resulting thermal displacements and stresses as functions of time. The subsidence and stress at the surface are compared with topography and tectonic features in the comparatively well-preserved Orientale basin. The results of the comparison are used as a basis to derive approximate constraints on the quantity and distribution of heat implanted during the basin-formation process.

Bratt, S. R.↗

Stress concentration measurement in a rectangular plate using an array of embedded optical fibers

Embedded single mode optical fiber waveguide has been used to determine the two-dimensional stress distribution produced by point loading on a simply supported rectangular plate. Each of the fifty individual fibers in the rectangular grid array attached to the plate yields a measurement of the stress integrated along the length of that fiber on the specimen. By using information from all the fibers, both the functional form and the amplitude of the distribution may be determined. Limits on the dynamic range and spatial resolution are indicated. Applications in the measurement of internal stress and the monitoring of physically small critical structural components are suggested.

Claus, R. O.↗

A new ply model for interlaminar stress analysis

An accurate estimate of interlaminar stresses is crucial to understanding, as well as predicting, many delamination-related failures in composite materials. A new model for ply-level sublaminate analysis is presented and applied. The homogeneous plate theory developed earlier by the authors (Valisetty and Rehfield, 1983) is further refined, and the equations are reduced appropriately for the classical finite-width free-edge laminate elasticity problem and a related delamination crack growth problem. It is applied to the laminate on a ply-by-ply basis. This theory incorporates all the essential physical effects and appears to be an adequate model for predicting the behavior of individual layers in equilibrium. On the basis of the number of equations and boundary conditions required for the implementation of layer equilibrium, this theory also appears to be the simplest of its kind presented so far. The stress induced in the free-edge region of a (0,90,90,0) laminate in uniform extension and the energy release rates for the delamination between the -30 deg and 90 deg plies of a (+, -30,+, -30, 90,90)s laminate are computed using the new analysis. The results are in excellent agreement with the existing numerical solutions. The new ply behavioral model appears to be very promising; it yields stresses and displacements that are statically and kinematically compatible at interlaminar surfaces.

Rao Valisetty, R.↗

Three-dimensional hybrid-stress finite element analysis of composite laminates with cracks and cutouts

A three-dimensional hybrid-stress finite element analysis of composite laminates containing cutouts and cracks is presented. Fully three-dimensional, hexahedral isoparametric elements of the hybrid-stress model are formulated on the basis of the Hellinger-Reissner variational principle. Traction-free edges, cutouts, and crack surfaces are modeled by imposition of exact traction boundary conditions along element surfaces. Special boundary and surface elements are constructed by introducing proper constraints on assumed stress functions. The Lagrangian multiplier technique is used to enforce ply-interface continuity conditions in hybrid bimaterial composite elements for modeling the interface region in a composite laminate. Two examples are given to illustrate the capability of the present method of approach: (1) the well-known delamination problem in an angle-ply laminate, and (2) the important problem of a composite laminate containing a circular hole. Results are presented in detail for each case. Implications of interlaminar and intralaminar crack initiation, growth and fracture in composites containing cracks and cutouts are discussed.

Wang, S. S.↗

Stress waves in isotropic elastic plate excited by circular transducer

Steady state harmonic stress waves in an isotropic elastic plate excited on one face by a circular transducer are analyzed theoretically. The transmitting transducer transforms an electrical voltage into a uniform normal stress at the top of the plate. To solve the boundary value problem,the radiation into a half-space is considered. The receiving transducer produces an electrical voltage proportional to the average spatially integrated normal stress over its face due to an incident wave. A numerical procedure is given to evaluate the frequency response at a receiving point due to a multiply reflected wave in the near field. Its stability and convergence are discussed. Parameterization plots which determine the particular wave whose frequency response has maximum magnitude compared with other multiple reflected waves are given for a range of values of dimensionless parameters. The effects of changes in the values of the parameters are discussed.

Williams, J. H., Jr.↗

Stress-intensity factors for circumferential surface cracks in pipes and rods under tension and bending loads

The purpose of this paper is to present stress-intensity factors for a wide range of nearly semi-elliptical surface cracks in pipes and rods. The configurations were subjected to either remote tension or bending loads. For pipes, the ratio of crack depth to crack length (a/c) ranged from 0.6 to 1; the ratio of crack depth to wall thickness (a/t) ranged from 0.2 to 0.8; and the ratio of internal radius to wall thickness (R/t) ranged from 1 to 10. For rods, the ratio of crack depth to crack length also ranged from 0.6 to 1; and the ratio of crack depth to rod diameter (a/D) ranged from 0.05 to 0.35. These particular crack configurations were chosen to cover the range of crack shapes (a/c) that have been observed in experiments conducted on pipes and rods under tension and bending fatigue loads. The stress-intensity factors were calculated by a three-dimensional finite-element method. The finite-element models employed singularity elements along the crack front and linear-strain elements elsewhere. The models had about 6500 degrees of freedom. The stress-intensity factors were evaluated using a nodal-force method.

Raju, I. S.↗

Thermal stresses in composite tubes

This paper summarizes work to determine the thermally-induced stresses and deformations in specially-constructed angle-ply composite tubes subjected to a uniform temperature change relative to their stress-free cure state. The tubes are designed for application to space structures and have high axial stiffness. Four angle-ply designs are examined in an effort to determine which design might have the most favorable thermally-induced response. A planar elasticity solution is used, the solution being valid away from the ends of the tube. Of the four designs considered, none has any particular advantage as far as stress levels are concerned. However, despite the fact that the tube wall is a balanced laminate, one design exhibits a significant amount of thermally-induced twist.

Hyer, M. W.↗

Stress analysis of Pathfinder-2 models

Stress analysis of the Pathfinder 2 fighter model was performed to determine a method for leading- and trailing-edge attachment that gives acceptable stress levels. Structural modeling of the wing was done using the finite element code SPAR. For the models studied, one ordinary lap joint was found to be satisfactory for the leading-edge flap, however, the alternating surface segmented lap joint method fo attachment was necessary for the trailing-edge flap to obtain acceptable stress levels.

Mehrotra, S. C.↗

Elastic-plastic stress concentrations around crack-like notches in continuous fiber reinforced metal matrix composites

Continuous fiber silicon-carbide/aluminum composite laminates with slits were tested statically to failure. Five different layups were examined: (0) sub 8, (0 sub 2/ + or - 45) sub s, (0/90) sub 2s), (0/ + or - 45/90 sub s), and (+ or - 45) sub 2s. Either a 9.5 or a 19 mm slit was machined in the center of each specimen. The strain distribution ahead of the slit tip was found experimentally with a series of strain gages bonded ahead of the slit tip. A three-dimensional finite element program (PAFAC) was used to predict the strain distribution ahead of the slit tip for several layups. For all layups, except the (0) sub 8, the yielding of the metal matrix caused the fiber stress concentration factor to increase with increasing load. This is contrary to the behavior seen in homogeneous materials where yielding causes the stress concentration to drop. For the (0) sub 8 laminate, yielding of the matrix caused a decrease in the fiber stress concentration. The finite element analysis predicted these trends correctly.

Johnson, W. S.↗

The effects of crack surface friction and roughness on crack tip stress fields

A model is presented which can be used to incorporate the effects of friction and tortuosity along crack surfaces through a constitutive law applied to the interface between opposing crack surfaces. The problem of a crack with a saw-tooth surface in an infinite medium subjected to a far-field shear stress is solved and the ratios of Mode-I stress intensity to Mode-II stress intensity are calculated for various coefficients of friction and material properties. The results show that tortuosity and friction lead to an increase in fracture loads and alter the direction of crack propagation.

Ballarini, Roberto↗

Reynolds number effects on surface shear stress patterns around isolated hemispheres

Obstacles projecting into the wind stream alter the shear stress on the surface around them, thus altering the erosion, transportation, and deposition of aeolian sediment. The effect of Reynolds number on the pattern of shear stress on the surface around an isolated hemisphere was investigated. An understanding of Reynolds number effects is necessary if wind tunnel results are to be scaled up to natural situations for meaningful applications. The experiment shows that the surface shear stress pattern is strongly affected by Reynolds number, at least within the range of Re used (1360 to 2977). This is presumably due to a decrease in flow around the sides of the hemisphere and an increase in flow over the object as the Reynolds number increases.

Lee, J. A.↗

Thermal stress analysis of space shuttle orbiter wing skin panel and thermal protection system

Preflight thermal stress analysis of the space shuttle orbiter wing skin panel and the thermal protection system (TPS) was performed. The heated skin panel analyzed was rectangular in shape and contained a small square cool region at its center. The wing skin immediately outside the cool region was found to be close to the state of elastic instability in the chordwise direction based on the conservative temperature distribution. The wing skin was found to be quite stable in the spanwise direction. The potential wing skin thermal instability was not severe enough to tear apart the strain isolation pad (SIP) layer. Also, the preflight thermal stress analysis was performed on the TPS tile under the most severe temperature gradient during the simulated reentry heating. The tensile thermal stress induced in the TPS tile was found to be much lower than the tensile strength of the TPS material. The thermal bending of the TPS tile was not severe enough to cause tearing of the SIP layer.

Ko, William L.↗

Stresses and deformations in angle-ply composite tubes

The stress and deformations in angle-ply composite tubes subjected to axisymmetric thermal loading were investigated both experimentally and analytically. For the theoretical portion a generalized plane strain elasticity analysis was developed. The analysis included mechanical and thermal loading, and temperature-dependent material properties. The elasticity analysis was also used to study the effect of including a thin metallic coating on a graphite-epoxy tube. The stresses in the coatings were found to be quite high, exceeding the yield stress of aluminum. An important finding in the analytical studies was the fact that even tubes with a balanced-symmetric lamination sequence exhibit shear deformation, or twist. For the experimental portion an apparatus was developed to measure torsional and axial response in the temperature range of 140 to 360 K. Eighteen specimens were tested, combining three material systems, eight lamination sequences, and three off-axis ply orientation angles. For the twist response, agreement between analysis and experiment was found to be good. The axial response of the tubes tested was found to be greater than predicted by a factor of three. As a result, it is recommended that the thermally induced axial deformations be investigated, both experimentally and analytically.

Rousseau, Carl Q.↗