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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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All sourcesNASA NTRSDOE OSTI
DOE OSTI2025

Scaling relations in the phase-space structure of dark matter haloes

We present new scaling relations for the isotropic phase-space distribution functions (DFs) and energy distributions of simulated dark matter haloes. These relations are inspired by those for the singular isothermal sphere with density profile $\rho (r)\propto r^{-2}$, for which the DF satisfies $f(E) \propto r_{\mathrm{max}}^{-2}(E)$ and the energy distribution satisfies $\mathrm{ d}M/\mathrm{ d}E \propto r_{\mathrm{max}}(E)$, with $r_{\mathrm{max}}(E)$ being the radius where the gravitational potential equals energy $E$. For the simulated haloes, we find $f(E)\propto r_{\mathrm{max}}^{-2.08}(E)$ and $\mathrm{ d}M/\mathrm{ d}E \propto r_{\mathrm{max}}(E)$ across broad energy ranges. In addition, the proportionality coefficients depend on the gravitational constant and the parameters of the best-fitting Navarro–Frenk–White density profile. These scaling relations are satisfied by haloes over a wide mass range and provide an efficient method to approximate their DFs and energy distributions. Understanding the origin of these relations may shed more light on halo formation.

galaxies: haloes↗
NASA NTRS2024

Flow Cytometry Methods to Monitor Immune System Dysregulation in Astronauts

Persistent immune system dysregulation has been documented to occur in astronauts participating in orbital spaceflight onboard the International Space Station. The phenomenon consists of reductions in T and NK cell function, altered cytokine profiles, persistent inflammation, and the subclinical reactivation of latent herpesviruses. In select crewmembers the dysregulation does actually lead to clinical symptoms, primarily atypical allergy or atopic dermatitis/zoster. Flow cytometry has served a central role defining the ‘immune assessment’ panel of assays that allow monitoring of astronauts. The cytometry assays which have been utilized include: 1. Peripheral leukocyte subsets 2. T cell function 3. Monocyte function 4. NK cell function 5. Intracellular cytokine analysis 6. Virus-specific T cell number (tetramer assay) 7. Virus-specific T cell function (peptide stimulation) 8. Leukocyte-bacterial challenge cytometry 9. Cytometric bead/multiplex array (soluble proteins) The use of these assays has been validated through various ISS flight investigations to define, to varying degrees, both in-flight, and post-flight immune system alterations. The kinetics of the dysregulation through the various phases of spaceflight, as well as post-flight recovery, have also been documented. To allow the science to occur within the orbital constraints of a spaceflight investigation, particular sample collection and processing techniques were developed compatible with the delays associated with terrestrial processing of in-flight samples. A subset of the assays has been adapted to routine monitoring of astronauts via a NASA ‘ISS Standard Measures’ activity, with the data from a specific crew then provided to all science investigators for that particular mission. This battery of cytometry assays has also been applied, through ground investigations, to several terrestrial ‘spaceflight analog’ populations. The purpose was to validate the analog which most closely replicates the in-flight observed pattern of alterations, generally believed to be winterover at an Antarctica station. To assist in determination of clinical risk, the assay panel has also been applied to investigations of various terrestrial patient populations, particularly zoster patients. As NASA is initiating crewed lunar missions via the ‘Artemis’ program, deployment of a miniaturized, microgravity-compatible flow cytometer, would be extremely beneficial to allow real time monitoring of crewmembers. Real time medical data could influence use of several countermeasures options during deep space missions. Several such instruments have been developed and validated to varying degrees of success. Assay details and summary findings across the various flight and ground platforms will be presented, as will current status in developing such technology for in-flight use.

Brian Crucian↗
DOE OSTI2024

Effect of parallel flow on resonant layer responses in high beta plasmas

Abstract Resonant layers in a tokamak respond to non-axisymmetric magnetic perturbations by amplifying the mode amplitude and balancing the plasma rotation through magnetic reconnection and force balance, respectively. This resonant response can be characterized by local layer parameters and especially by a single quantity in the linear regime, the so-called inner-layer Δ. The computation of Δ under two-fluid drift-MHD formalism has been progressed by reducing the order of the system in the phase space, where the shielding current is approximated as being only carried by electrons, a posteriori . In this study, we relax the approximation and compute Δ accounted for by the parallel flow associated with the ion shielding current. The posteriori is numerically verified in great agreement with the original SLAYER developed in a previous paper (J.-K. Park 2022 Phys. Plasmas 29 072506). Extending the resonant layer response theory to high β plasmas, our research findings answer two important questions: how the parallel flow influences the resonant layer response and why the parallel flow effect appears in high β plasmas. The complicated plasma compression in high β regime allows the parallel flow response to give rise to the ion shielding current, which not only shifts the zero-crossing condition of the ExB flow but also enhances the field penetration threshold. Technically, the Riccati matrix transformation method is adapted to handle the numerical stiffness due to the increased order of the system. The high fidelity of this numerical method makes use of further extension of the model to higher-order systems to take other physical phenomena into account. This work is envisaged to predict the resonant layer response under high β fusion reactor conditions.

Lee, Yeongsun (ORCID:000000034474416X)↗
NASA NTRS1993

Analysis of rocket beacon transmissions for computerized reconstruction of ionospheric densities

Three methods are described to obtain ionospheric electron densities from transionospheric, rocket-beacon TEC data. First, when the line-of-sight from a ground receiver to the rocket beacon is tangent to the flight trajectory, the electron concentration can be obtained by differentiating the TEC with respect to the distance to the rocket. A similar method may be used to obtain the electron-density profile if the layer is horizontally stratified. Second, TEC data obtained during chemical release experiments may be interpreted with the aid of physical models of the disturbed ionosphere to yield spatial maps of the modified regions. Third, computerized tomography (CT) can be used to analyze TEC data obtained along a chain of ground-based receivers aligned along the plane of the rocket trajectory. CT analysis of TEC data is used to reconstruct a 2D image of a simulated equatorial plume. TEC data is computed for a linear chain of nine receivers with adjacent spacings of either 100 or 200 km. The simulation data are analyzed to provide an F region reconstruction on a grid with 15 x 15 km pixels. Ionospheric rocket tomography may also be applied to rocket-assisted measurements of amplitude and phase scintillations and airglow intensities.

Bernhardt, P. A.↗
DOE OSTI2025

Isochronous and period-doubling diagrams for symplectic maps of the plane

Symplectic mappings of the plane serve as key models for exploring the fundamental nature of complex behavior in nonlinear systems. Central to this exploration is the effective visualization of stability regimes, which enables the interpretation of how systems evolve under varying conditions. While the area-preserving quadratic Hénon map has received significant theoretical attention, a comprehensive description of its mixed parameter-space dynamics remain lacking. This limitation arises from early attempts to reduce the full two-dimensional phase space to a one-dimensional projection, a simplification that resulted in the loss of important dynamical features. Consequently, there is a clear need for a more thorough understanding of the underlying qualitative aspects. This paper aims to address this gap by revisiting the foundational concepts of reversibility and associated symmetries, first explored in the early works of G.D. Birkhoff. We extend the original framework proposed by Hénon by adding a period-doubling diagram to his isochronous diagram, which allows to represents the system’s bifurcations and the groups of symmetric periodic orbits that emerge in typical bifurcations of the fixed point. A qualitative and quantitative explanation of the main features of the region of parameters with bounded motion is provided, along with the application of this technique to other symplectic mappings, including cases of multiple reversibility. Modern chaos indicators, such as the Reversibility Error Method (REM) and the Generalized Alignment Index (GALI), are employed to distinguish between various dynamical regimes in the mixed space of variables and parameters. These tools prove effective in differentiating regular and chaotic dynamics, as well as in identifying twistless orbits and their associated bifurcations. Additionally, we discuss the application of these methods to real-world problems, such as visualizing dynamic aperture in accelerator physics, where our findings have direct relevance.

43 PARTICLE ACCELERATORS↗
NASA NTRS2010

Modeling Of Metabolic Heat Regenerated Temperature Swing Adsorption (MTSA) Subassembly For Prototype Design

This paper describes modeling methods for the three core components of a Metabolic heat regenerated Temperature Swing Adsorption (MTSA) subassembly: a sorbent bed, a sublimation (cooling) heat exchanger (SHX), and a condensing icing (warming) heat exchanger (CIHX). The primary function of the MTSA, removing carbon dioxide from a space suit Portable Life Support System (PLSS) ventilation loop, is performed via the sorbent bed. The CIHX is used to heat the sorbent bed for desorption and to remove moisture from the ventilation loop while the SHX is alternately employed to cool the sorbent bed via sublimation of a spray of water at low pressure to prepare the reconditioned bed for the next cycle. This paper describes subsystem heat a mass transfer modeling methodologies relevant to the description of the MTSA subassembly in Thermal Desktop and SINDA/FLUINT. Several areas of particular modeling interest are discussed. In the sorbent bed, capture of the translating carbon dioxide (CO2) front and associated local energy and mass balance in both adsorbing and desorbing modes is covered. The CIHX poses particular challenges for modeling in SINDA/FLUINT as accounting for solids states in fluid submodels are not a native capability. Methods for capturing phase change and latent heat of ice as well as the transport properties across a layer of low density accreted frost are developed. This extended modeling capacity is applicable to temperatures greater than 258 K. To extend applicability to the minimum device temperature of 235 K, a method for a mapped transformation of temperatures from below the limit temperatures to some value above is given along with descriptions for associated material property transformations and the resulting impacts to total heat and mass transfer. Similar considerations are given for the SHX along with functional relationships for areal sublimation rates as limited by flow mechanics in t1he outlet duct.

Bower, Chad E.↗
NASA NTRS2014

OCCAMS: Optically Controlled and Corrected Active Meta-Material Space Structures

Telescopes require sub-wavelength figure (shape) error in order to achieve acceptable Strehl ratios. Traditional methods of achieving this require rigid and therefore heavy mirrors and reaction structures as well as proportionally heavy and expensive spacecraft busses and launch vehicles. This effectively limits the diameter and therefore resolution and collecting area of space optics. Large diameter telescopes must either be heavy or actively controlled. Space telescopes of the size proposed for missions such as TPF (Terrestrial Planet Finder), TPI (Terrestrial Planet Imager), etc. will likely require large active primaries and structures and corrective optics to implement downstream wavefront control. We propose a novel viable enabling technology. High resolution space imaging requires the production of lightweight large aperture optics subject to design tradespace constraints based on nanometer physical tolerances, low system aerial density, high control authority, suitable thermal and mechanical properties, deployment capability, launch vehicle volume constraints, as well as production cost and schedule risk mitigation. Segmented systems impose additional requirements on segment alignment, wavefront phasing, and telescope mass with increased edge diffraction. Photons weigh nothing. Why must even small space telescopes "weigh" tons? Our team is working to demonstrate that they do not, by leveraging 15 years of effort and a novel advanced concept.The ultimate research goal is to refine technology to produce a mission capable ultra-lightweight membrane optic whose shape can be remotely controlled using a laser beam. Using our novel optically-controlled molecular actuators allows substitution of optically-induced control for rigidity and mirror mass. In analogy with noise-canceling headphones, this technique also potentially provides a way to excite vibratory modes to couple with and damp out normal modes of oscillation induced by slewing, other motion and thermal changes, thus allowing a robust response to repointing of a large aperture.

Astronomy↗
NASA NTRS1993

Spatial interpretation of NASA's Marshall Space Flight Center Payload Operations Control Center using virtual reality technology

In its search for higher level computer interfaces and more realistic electronic simulations for measurement and spatial analysis in human factors design, NASA at MSFC is evaluating the functionality of virtual reality (VR) technology. Virtual reality simulation generates a three dimensional environment in which the participant appears to be enveloped. It is a type of interactive simulation in which humans are not only involved, but included. Virtual reality technology is still in the experimental phase, but it appears to be the next logical step after computer aided three-dimensional animation in transferring the viewer from a passive to an active role in experiencing and evaluating an environment. There is great potential for using this new technology when designing environments for more successful interaction, both with the environment and with another participant in a remote location. At the University of North Carolina, a VR simulation of a the planned Sitterson Hall, revealed a flaw in the building's design that had not been observed during examination of the more traditional building plan simulation methods on paper and on computer aided design (CAD) work station. The virtual environment enables multiple participants in remote locations to come together and interact with one another and with the environment. Each participant is capable of seeing herself and the other participants and of interacting with them within the simulated environment.

Lindsey, Patricia F.↗
DOE OSTI2023

Integrated control of edge localized modes and divertor flux using mixed toroidal harmonic resonant magnetic perturbations in EAST

Mixed harmonic resonant magnetic perturbations (RMPs) for integrated edge localized modes (ELMs) and divertor flux control are demonstrated in EAST target plasmas of low input torque and normalized beta β N ~1.7–1.9, which are close to the equivalent value in ITER high Q operation. The applied RMPs are designed to combine a static harmonic of the toroidal mode number n = 3 with a static or rotating harmonic of n = 2. ELM suppression is achieved without a drop of plasma energy confinement, and tungsten concentration is effectively reduced during the application of RMPs. With mixed harmonics, the toroidal varying steady state heat and particle fluxes on the divertor target can be modified with the rotating n = 2 harmonic, which agrees with the numerical modeling of three-dimensional magnetic topology, with plasma responses being taken into account. ELM suppression correlates with the times of larger n = 3 response with mixed n = 2 and n = 3 RMPs. The mixture of harmonics and the rotating n = 2 harmonic does not require additional coil current because the variation is only in the upper-lower coil current phase space. Furthermore, these results further affirm the effectiveness of integrated ELM and divertor flux control using RMPs with mixed harmonics and improve the understanding of the role of plasma responses in ELM suppression.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2024

Structural Evolution and Photoluminescence Quenching across the FASnI 3– x Br x ( x = 0–3) Perovskites

One of the primary methods for band gap tuning in metal halide perovskites has been halide (I/Br) mixing. Despite widespread usage of this type of chemical substitution in perovskite photovoltaics, there is still little understanding of the structural impacts of halide alloying, with the assumption being the formation of ideal solid solutions. The FASnI 3–x Br x (x = 0–3) family of compounds provides the first example where the assumption breaks down, as the composition space is broken into two unique regimes (x = 0–2.9; x = 2.9–3) based on their average structure with the former having a 3D and the latter having an extended 3D (pseudo 0D) structure. Pair distribution function (PDF) analyses further suggest a dynamic 5s 2 lone pair expression resulting in increasing levels of off-centering of the central Sn as the Br concentration is increased. These antiferroelectric distortions indicate that even the x = 0–2.9 phase space behaves as a nonideal solid-solution on a more local scale. Solid-state NMR confirms the difference in local structure yielding greater insight into the chemical nature and local distributions of the FA + cation. In contrast to the FAPbI 3–x Br x series, a drastic photoluminescence (PL) quenching is observed with x ≥ 1.9 compounds having no observable PL. In conclusion, our detailed studies attribute this quenching to structural transitions induced by the distortions of the [SnBr 6 ] octahedra in response to stereochemically expressed lone pairs of electrons. This is confirmed through density functional theory, having a direct impact on the electronic structure.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
NASA NTRS2012

Space Launch System Accelerated Booster Development Cycle

With the retirement of the Space Shuttle, NASA is seeking to reinvigorate the national space program and recapture the public s interest in human space exploration by developing missions to the Moon, near-earth asteroids, Lagrange points, Mars, and beyond. The would-be successor to the Space Shuttle, NASA s Constellation Program, planned to take humans back to the Moon by 2020, but due to budgetary constraints was cancelled in 2010 in search of a more "affordable, sustainable, and realistic" concept2. Following a number of studies, the much anticipated Space Launch System (SLS) was unveiled in September of 2011. The SLS core architecture consists of a cryogenic first stage with five Space Shuttle Main Engines (SSMEs), and a cryogenic second stage using a new J-2X engine3. The baseline configuration employs two 5-segment solid rocket boosters to achieve a 70 metric ton payload capability, but a new, more capable booster system will be required to attain the goal of 130 metric tons to orbit. To this end, NASA s Marshall Space Flight Center recently released a NASA Research Announcement (NRA) entitled "Space Launch System (SLS) Advanced Booster Engineering Demonstration and/or Risk Reduction." The increased emphasis on affordability is evident in the language used in the NRA, which is focused on risk reduction "leading to an affordable Advanced Booster that meets the evolved capabilities of SLS" and "enabling competition" to "enhance SLS affordability. The purpose of the work presented in this paper is to perform an independent assessment of the elements that make up an affordable and realistic path forward for the SLS booster system, utilizing advanced design methods and technology evaluation techniques. The goal is to identify elements that will enable a more sustainable development program by exploring the trade space of heavy lift booster systems and focusing on affordability, operability, and reliability at the system and subsystem levels5. For this study, affordability is defined as lifecycle cost, which includes design, development, test, and engineering (DDT&E), production and operational costs (P&O). For this study, the system objectives include reducing DDT&E schedule by a factor of three, showing 99.9% reliability, flying up to four times per year, serving both crew and cargo missions, and evolving to a lift capability of 130 metric tons.3 After identifying gaps in the current system s capabilities, this study seeks to identify non-traditional and innovative technologies and processes that may improve performance in these areas and assess their impacts on booster system development. The DDT&E phase may be improved by incorporating incremental development testing and integrated demonstrations to mitigate risk. To further reduce DDT&E, this study will also consider how aspects of the booster system may have commonality with other users, such as the Department of Defense, commercial applications, or international partners; by sharing some of the risk and investment, the overall development cost may be reduced. Consideration is not limited to solid and liquid rocket boosters. A set of functional performance characteristics, such as engine thrust, specific impulse (Isp), mixture ratio, and throttle range are identified and their impacts on the system are evaluated. This study also identifies how such characteristics affect overall life cycle cost, including DDT&E and fixed and variable P&O.

Arockiam, Nicole↗
DOE OSTI2021

Investigating Covalent Bonding in f-elements using Gas-phase Ion Chemistry

Introduction In the reprocessing of f-elements present in used nuclear fuels, a variety of diglycolamides (DGA’s) are used as extractants for actinide partitioning. In particular, the Actinide-Lanthanide Separation (ALSEP) process typically utilizes either the N,N,N’,N’-tetraoctyl diglycolamide (TODGA) or N,N,N',N'-tetra-2-ethylhexyl diglycolamide (T2EHDGA) extractant ligands following the partitioning of uranium and plutonium from used nuclear fuel. To better understand fundamental interactions in these processes, covalent bonding of several f-elements with diglycolamides, primarily TODGA, is investigated in the gas phase using nanospray ionization and a quadrupole time-of-flight mass spectrometer. Further, analysis of the identity and relative strength of the cluster is enabled by MS2 isolation and collision induced dissociation. Methods Metal ion cluster analysis was completed using a Bruker mircOTOF-Q II quadrupole time-of-flight mass spectrometer equipped with a CaptiveSpray nanospray ion source. Metal:ligand solutions were prepared as 30 µM europium nitrate, samarium nitrate, cerium nitrate, or holmium nitrate and 3 µM DGA in acetonitrile or a 50:50 mixture of acetonitrile: isopropanol. Cluster mass spectra and collision-induced dissociation experiments were conducted in positive mode. Preliminary data To examine the patterns and relative strength of lanthanide: DGA interactions, MS2 experiments were completed with each lanthanide species listed above. Preliminary analyses of samarium and europium TODGA clusters suggest several combinations of TODGA and nitrate forming. The samarium cluster experiments yielded Sm(TODGA)x clusters with a samarium:TODGA ratio of up to 1:7 able to be isolated and evidence of greater ratios present in the mass spectrum. This is surprising, as metal clusters are not expected to have a coordination space able to accommodate this many ligands as large as TODGA. MS2 experiments show that, at higher ratios and with sufficient collision energy, entire TODGA ligands are removed instead of being fragmented. These experiments show that a lower collision energy is required to remove ligands as the number of bound TODGA’s increases, suggesting that in larger clusters, ligands are more delicately complexed to the metal. In addition to Sm(TODGA)x, several clusters were observed with nitrate ions bound to the metal in addition to TODGA. With a single nitrate ion, clusters with up to six TODGA’s were able to be isolated. In a similar pattern to the samarium clusters with only TODGA, less collision energy is required to eliminate one or more TODGA’s with increasing size. MS2 experiments suggest clusters with one nitrate appear to be of an equivalent or greater stability to clusters which replace the nitrate with a TODGA, as more collision energy is required to remove a TODGA ligand. These species with one nitrate are also in a higher abundance than the equivalent TODGA only cluster. With two nitrate ions, only clusters with a single TODGA were able to be isolated. Analogous europium experiments resulted in very similar clusters. Ratios of up to 1:7 Eu:TODGA were able to be isolated, and clusters with one nitrate and up to five TODGAs were isolated. In clusters with two nitrate ions, one or two TODGA’s could also be bound to the metal. MS2 experiments suggested, similarly to samarium, that larger clusters required less collision energy to eliminate TODGA. Europium clusters with one nitrate are in greater abundance and are stronger than the equivalent cluster which replaces the nitrate with TODGA. Similar analysis with cerium and holmium is ongoing, as well as analysis with other DGA ligands to compare relative strengths of the lanthanide metals with various extractant ligands.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2023

Coherent correlation imaging for resolving fluctuating states of matter

Fluctuations and stochastic transitions are ubiquitous in nanometre-scale systems, especially in the presence of disorder. However, their direct observation has so far been impeded by a seemingly fundamental, signal-limited compromise between spatial and temporal resolution. Here we develop coherent correlation imaging (CCI) to overcome this dilemma. Our method begins by classifying recorded camera frames in Fourier space. Contrast and spatial resolution emerge by averaging selectively over same-state frames. Temporal resolution down to the acquisition time of a single frame arises independently from an exceptionally low misclassification rate, which we achieve by combining a correlation-based similarity metric with a modified, iterative hierarchical clustering algorithm. We apply CCI to study previously inaccessible magnetic fluctuations in a highly degenerate magnetic stripe domain state with nanometre-scale resolution. We uncover an intricate network of transitions between more than 30 discrete states. Our spatiotemporal data enable us to reconstruct the pinning energy landscape and to thereby explain the dynamics observed on a microscopic level. CCI massively expands the potential of emerging high-coherence X-ray sources and paves the way for addressing large fundamental questions such as the contribution of pinning and topology in phase transitions and the role of spin and charge order fluctuations in high-temperature superconductivity.

36 MATERIALS SCIENCE↗
DOE OSTI2020

Path Properties of Atmospheric Transitions: Illustration with a Low-Order Sudden Stratospheric Warming Model

Many rare weather events, including hurricanes, droughts, and floods, dramatically impact human life. To accurately forecast these events and characterize their climatology requires specialized mathematical techniques to fully leverage the limited data that are available. Here we describe transition path theory (TPT), a framework originally developed for molecular simulation, and argue that it is a useful paradigm for developing mechanistic understanding of rare climate events. TPT provides a method to calculate statistical properties of the paths into the event. As an initial demonstration of the utility of TPT, we analyze a low-order model of sudden stratospheric warming (SSW), a dramatic disturbance to the polar vortex that can induce extreme cold spells at the surface in the midlatitudes. SSW events pose a major challenge for seasonal weather prediction because of their rapid, complex onset and development. Climate models struggle to capture the long-term statistics of SSW, owing to their diversity and intermittent nature. We use a stochastically forced Holton–Mass-type model with two stable states, corresponding to radiative equilibrium and a vacillating SSW-like regime. In this stochastic bistable setting, from certain probabilistic forecasts TPT facilitates estimation of dominant transition pathways and return times of transitions. These “dynamical statistics” are obtained by solving partial differential equations in the model’s phase space. With future application to more complex models, TPT and its constituent quantities promise to improve the predictability of extreme weather events through both generation and principled evaluation of forecasts.

54 ENVIRONMENTAL SCIENCES↗
NASA NTRS2010

Pharmacokinetics of Scopolamine Intranasal Gel Formulation (INSCOP) During Antiorthostatic Bedrest

Space Motion Sickness (SMS) is experienced during early flight days of space missions and on reduced gravity simulation flights which require treatment with medications. Oral administration of scopolamine tablets is still a common practice to prevent SMS symptoms. Bioavailability of medications taken by mouth for SMS is often low and variable. Intranasal (IN) administration of medications has been reported to achieve higher and more reliable bioavailability than from an equivalent oral dose. In this FDA reviewed phase II clinical trial, we evaluated pharmacokinetics of an investigative new drug formulation, INSCOP during ambulatory (AMB) and antiorthostatic bedrest (HBR), a ground-based microgravity analog. Twelve subjects including 6 males and 6 females received 0.2 and 0.4 mg doses of INSCOP on separate days during AMB and ABR in a randomized, double blind cross over experimental design. Blood samples were collected at regular time intervals for 24 h post dose and analyzed for free scopolamine concentrations by an LC-MS-MS method. Pharmacokinetic parameters were calculated using concentration versus time data and compared between AMB and ABR conditions. Results indicated that maximum concentration and relative bioavailability increased marginally during ABR compared to AMB; differences in PK parameters between AMB and ABR were greater with 0.2 mg than with 0.4 mg dose. Gender specific differences in PK parameters was observed both during AMB and ABR with differences higher in females between the two conditions than in males. A significant observation is that while gender differences in PK appear to exist, the differences in primary PK parameters between AMB and ABR after IN administration, unlike oral administration, are minimal and may not be clinically significant for both genders.

Putcha, L.↗
NASA NTRS2010

Launch Pad Coatings for Smart Corrosion Control

Corrosion is the degradation of a material as a result of its interaction with the environment. The environment at the KSC launch pads has been documented by ASM International (formerly American Society for Metals) as the most corrosive in the US. The 70 tons of highly corrosive hydrochloric acid that are generated by the solid rocket boosters during a launch exacerbate the corrosiveness of the environment at the pads. Numerous failures at the pads are caused by the pitting of stainless steels, rebar corrosion, and the degradation of concrete. Corrosion control of launch pad structures relies on the use of coatings selected from the qualified products list (QPL) of the NASA Standard 5008A for Protective Coating of Carbon Steel, Stainless Steel, and Aluminum on Launch Structures, Facilities, and Ground Support Equipment. This standard was developed to establish uniform engineering practices and methods and to ensure the inclusion of essential criteria in the coating of ground support equipment (GSE) and facilities used by or for NASA. This standard is applicable to GSE and facilities that support space vehicle or payload programs or projects and to critical facilities at all NASA locations worldwide. Environmental regulation changes have dramatically reduced the production, handling, use, and availability of conventional protective coatings for application to KSC launch structures and ground support equipment. Current attrition rate of qualified KSC coatings will drastically limit the number of commercial off the shelf (COTS) products available for the Constellation Program (CxP) ground operations (GO). CxP GO identified corrosion detection and control technologies as a critical, initial capability technology need for ground processing of Ares I and Ares V to meet Constellation Architecture Requirements Document (CARD) CxP 70000 operability requirements for reduced ground processing complexity, streamlined integrated testing, and operations phase affordability. Researchers at NASA's Corrosion Technology Laboratory at KSC are developing a smart, environmentally friendly coating system for early corrosion detection, inhibition, and self healing of mechanical damage without external intervention. This smart coating will detect and respond actively to corrosion and mechanical damage such as abrasion and scratches, in a functional and predictable manner, and will be capable of adapting its properties dynamically. This coating is being developed using corrosion sensitive microcapsules that deliver the contents of their core (corrosion inhibiting compounds, corrosion indicators, and self healing agents) on demand when corrosion or mechanical damage to the coating occurs.

Calle, Luz M.↗
NASA NTRS2020

Q4 – A CubeSat Mission to Demonstrate Omnidirectional Optical Communications

We are proposing a technology demonstration mission for JPL’s Inter-Satellite Optical Communicator (ISOC). The ISOC has the potential to enable up to 1 Gbps data rates over a distance up to 200 km in free space. Key features of the ISOC include full sky coverage and the ability to maintain multiple links simultaneously. The Q4 mission consists of (4) 6U CubeSats furnished with ISOCs to demonstrate high data rate communications among the spacecraft. More specifically, we seek to demonstrate the omnidirectionality of the ISOC by providing simultaneous optical links between one spacecraft and the other three. Q4 will be a demonstrator for small spacecraft swarm capabilities. Following a proposed deployment from the ISS, the CubeSats will utilize their onboard thrusters to enter their desired orbit. The orbit consists of one “leader” spacecraft in a circular orbit with a 400 km LEO altitude and three “follower” spacecraft in slightly elliptical orbits rotating azimuthally about the leader. The main mission will consist of three consecutive phases: First, the spacecraft will demonstrate pointing, acquisition, and tracking using newly developed protocols. Next, link establishment and different channel access methods (CDMA and TDMA) will be tested. Finally, Delay Tolerant Network protocols will be implemented to allow fast data sharing among the spacecraft. The distance between the communicating spacecraft will be increased as the mission progresses to characterize the link quality as a function of distance. All communications over the course of the mission will be recorded and analyzed on the ground using bit error rate as a metric for success. The current design for each the four Q4 CubeSats contains an XACT advanced ADCS system for precision beam pointing. Other components currently under consideration include MiPS cold gas thrusters for orbital maneuvering and gimbaled eHaWK 84W solar arrays. In this paper we present design considerations for the Q4 CubeSats, link budget calculations, results from preliminary mission analysis, and expected results.

Velazco, Jose E↗