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Life sciences recruitment objectives

The goals of the Life Sciences Division of the Office of Space Sciences and Application are to ensure the health, well being and productivity of humans in space and to acquire fundamental scientific knowledge in space life sciences. With these goals in mind Space Station Freedom represents substantial opportunities and significant challenges to the Life Sciences Division. For the first time it will be possible to replicate experimental data from a variety of simultaneously exposed species with appropriate controls and real-time analytical capabilities over extended periods of time. At the same time, a system for monitoring and ameliorating the physiological adaptations that occur in humans subjected to extended space flight must be evolved to provide the continuing operational support to the SSF crew. To meet its goals, and take advantage of the opportunities and overcome the challenges presented by Space Station Freedom, the Life Sciences Division is developing a suite of discipline-focused sequence. The research phase of the Life Sciences Space Station Freedom Program will commence with the utilization flights following the deployment of the U.S. laboratory module and achievement of Man Tended Capability. Investigators that want the Life Sciences Division to sponsor their experiment on SSF can do so in one of three ways: submitting a proposal in response to a NASA Research Announcement (NRA), submitting a proposal in response to an Announcement of Opportunity (AO), or submitting an unsolicited proposal. The scientific merit of all proposals will be evaluated by peer review panels. Proposals will also be evaluated based on relevance to NASA's missions and on the results of an Engineering and Cost Analyses. The Life Sciences Division expects that the majority of its funding opportunities will be announced through NRA's. It is anticipated that the first NRA will be released approximately three years before first element launch (currently scheduled for late 1995). Subsequent NRA's will be released on a rotating two year cycle.

Keefe, J. Richard↗

The X-ray selected cataclysmic variables H0459 + 246 and H0857 - 242

We report the discovery of two cataclysmic variables located with the assistance of X-ray positions from the HEAO 1 Modulation Collimator and the Large-Area Sky Survey. Each case is distinguished by evidence of two periodic modulations that appear to represent the orbital period and the spin period of the white dwarf, respectively. The first case, H0459 + 246, has been observed optically during faint states (V approximately 16), in which there are spectral features of both an accretion disk and a K star. The light curves in the V and I bands are consistent with ellipsoidal variations in the secondary stars with a binary period of 9.952 hr. X-ray observations with EXOSAT reveal a strong pulsation with a period approximately 62 minutes. This result confirms an 'intermediate polar' classification for H0459 + 246. The pulsation is observed at 63.2 minutes in the optical I band. The long orbital period opens the possibility that H0459 + 246 is a relatively young intermediate polar that might evolve into a polar. The second case, H0857--242, shows radial velocity modulations at 1.78 hr along with photometric variations at a period approximately 49 minutes. The latter are observed only during the decay phase of dwarf nova outbursts (13 less than V less than 17), which apparently recur frequently. Given the lack of X-ray monitoring observations and the absence of proof that the 49 minute periodicity is coherent over long time-scales, we regard H0857--242 as a candidate intermediate polar. Photographic records from th e Harvard Observatory Plate Library further reveal superoutbursts for H0857--242 (V approximately 11). A bright X-ray source that is both an intermediate polar and a continually cycling dwarf nova may provide an effective means of measuring the time delay for the arrival of accreting matter at the white dwarf surface, relative to the onset of optical brightening.

Remillard, R. A.↗

Twenty years of interplanetary magnetic field variations with periods in the range of 10 days to 3 years

Twenty years of interplanetary magnetic field data collected primarily by the IMP-8 spacecraft near Earth has been analyzed by a dynamic periodogram method in search of significant periodicities in the range of 10 days to 3 years. The method has the advantage of detecting variations with time in the periodicities besides determining the power and phase of the dominant variations. It has been found that the well known periodicities near 1 year and 27 days are strongly modulated by the solar cycle. Both of these periodicities are only detected during solar minimum. During solar maximum. a number of unusual variations are observed. Special emphasis will be placed on the recently reported 1.3 year variation in solar wind parameters besides periods in the interplanetary magnetic field near 51, 73 and 154 days. Correlations with solar wind plasma and solar index variations will also be presented.

Szabo, A.↗

Solar-Driven Neutral Density Waves

Interstellar neutral hydrogen atoms flowing into the solar system are attracted by the solar gravitational force, repelled by solar hydrogen Ly-alpha radiation pressure, and are ionized, primarily, through charge exchange with the solar wind protons. The solar cycle variation of the radiation pressure causes the net central solar force to fluctuate between attraction and repulsion resulting in the modulation of the neutral hydrogen density about the usual time independent model. The calculation presented here shows that the time dependent downstream density is strongly modulated by a large number of travelling neutral density waves. The waves possess a continuous range of wavelengths as is to be expected for a Maxwellian gas subjected to several eleven year cycle variations during its journey through the solar system. The amplitudes of the density modulation were found to be quite large. The backscattered glow was found to depend on the position of the detector and the phase of the solar cycle. At the most favorable condition a deviation of the order of 25% from the time dependent glow might be observed.

Blum, P.↗

Fabricating High Resolution Mirrors for Hand X-Ray Astronomy

We describe the fabrication process for producing high-resolution conical mirrors for hard x-ray astronomy. When flown aboard stratospheric balloons, these high-resolution reflective mirrors focus hard x-rays (10-70 keV) emitted from cosmic sources such as supernovae, neutron stars, and quasars onto imaging focal plane detectors. Focused hard x-ray images allow scientists to determine the elemental compositions, temperatures, magnetic fields, velocities, and gravitational fields of these celestial bodies. The fabrication process involves generating super-polished mandrels, mandrel metrology, mirror shell nickel electroforming, and mirror testing. Each mandrel is a cylinder consisting of two conical segments; each segment is approximately 305-mm long. Through precision grinding these mandrels before super polishing, we have achieved 30 arc seconds, half power diameter replicated mirrors. During a May 2001 high atmosphere balloon flight, these mirrors focused high energy x-rays from three different celestial sources. However, we seek to improve the angular resolutions of future mirror shells by a factor of two. To achieve this goal, we have begun single point diamond turning the mandrels before super polishing. This has allowed greater precision tolerances on mandrel surface roughness and axial figure errors before super polishing. Surface roughnesses before polishing have been reduced from approximately 60 nm to approximately 15 nm. The peak to valley axial figure profile errors have been reduced from approximately 1.0 micrometers to approximately 0.4 micrometers. We are currently in Phase 2 of the HERO (high energy replicated optics) program which entails the production of sixteen 6-m-focal-length mirror modules, each containing a nested array of 15 mirror shells of diameters ranging from 50-mm to 94-mm. This flight is slated for the fall of 2003.

Speegle, Chet O.↗

Estimation of Time Scales in Unsteady Flows in a Turbomachinery Rig

Time scales in turbulent and transitional flow provide a link between experimental data and modeling, both in terms of physical content and for quantitative assessment. The problem of interest here is the definition of time scales in an unsteady flow. Using representative samples of data from GEAE low pressure turbine experiment in low speed research turbine facility with wake-induced transition, we document several methods to extract dominant frequencies, and compare the results. We show that conventional methods of time scale evaluation (based on autocorrelation functions and on Fourier spectra) and wavelet-based methods provide similar information when applied to stationary signals. We also show the greater flexibility of the wavelet-based methods when dealing with intermittent or strongly modulated data, as are encountered in transitioning boundary layers and in flows with unsteady forcing associated with wake passing. We define phase-averaged dominant frequencies that characterize the turbulence associated with freestream conditions and with the passing wakes downstream of a rotor. The relevance of these results for modeling is discussed in the paper.

Lewalle, Jacques↗

Receptivity of Supersonic Boundary Layers Due To Acoustic Disturbances Over Blunt Cones

Receptivity and stability of supersonic boundary layers over a 5-degree straight cone with a blunt tip are numerically investigated at a free stream Mach number of 3.5 and at a high Reynolds number of 106/inch. Both the steady and unsteady solutions are obtained by solving the full Navier-Stokes equations using the 5th-order accurate weighted essentially non-oscillatory (WENO) scheme for space discretization and using third-order total-variation-diminishing (TVD) Runge-Kutta scheme for time integration. The linear stability results showed that bluntness has less stabilizing effects on the stability of boundary layers over cones than on flat plates and wedges. The unsteady simulations of the interaction of plane threedimensional acoustic waves with the cone showed that the modulation of wavelength and the generation of instability waves first occurred near the leading edge in the plane where the constant acoustic phase lines are perpendicular to the cone axis. Further downstream, this instability region spreads in the azimuthal direction from this plane.

Balakumar, P.↗

Full-Circle Resolver-to-Linear-Analog Converter

A circuit generates sinusoidal excitation signals for a shaft-angle resolver and, like the arctangent circuit described in the preceding article, generates an analog voltage proportional to the shaft angle. The disadvantages of the circuit described in the preceding article arise from the fact that it must be made from precise analog subcircuits, including a functional block capable of implementing some trigonometric identities; this circuitry tends to be expensive, sensitive to noise, and susceptible to errors caused by temperature-induced drifts and imprecise matching of gains and phases. These disadvantages are overcome by the design of the present circuit. The present circuit (see figure) includes an excitation circuit, which generates signals Ksin(Omega(t)) and Kcos(Omega(t)) [where K is an amplitude, Omega denotes 2(pi)x a carrier frequency (the design value of which is 10 kHz), and t denotes time]. These signals are applied to the excitation terminals of a shaft-angle resolver, causing the resolver to put out signals C sin(Omega(t)-Theta) and C cos(Omega(t)-Theta). The cosine excitation signal and the cosine resolver output signal are processed through inverting comparator circuits, which are configured to function as inverting squarers, to obtain logic-level or square-wave signals .-LL[cos(Omega(t)] and -LL[cos(Omega(t)-Theta)], respectively. These signals are fed as inputs to a block containing digital logic circuits that effectively measure the phase difference (which equals Theta between the two logic-level signals). The output of this block is a pulse-width-modulated signal, PWM(Theta), the time-averaged value of which ranges from 0 to 5 VDC as Theta ranges from .180 to +180deg. PWM(Theta) is fed to a block of amplifying and level-shifting circuitry, which converts the input PWM waveform to an output waveform that switches between precise reference voltage levels of +10 and -10 V. This waveform is processed by a two-pole, low-pass filter, which removes the carrier-frequency component. The final output signal is a DC potential, proportional to Theta that ranges continuously from -10 V at Theta = -180deg to +10 V at Theta = +180deg..

Alhorn, Dean C.↗

Multiple trellis coded modulation (MTCM) performance on a fading mobile satellite channel

The author recently introduced the notion of multiple trellis coding, in which more than one channel symbol per trellis branch is transmitted. He showed that on the ideal additive white Gaussian noise (AWGN) channel, the combination of multiple trellis coding with M-ary modulation yields a performance gain with symmetric signal sets comparable to and in some cases better than that previously achieved only with signal constellation asymmetry. The combination of conventional trellis coding with multiple phase-shift-keyed (MPSK) signaling has recently been shown by the author to be a well-suited modulation/coding scheme for transmission over the fading mobile satellite channel. In particular, a rate 2/3 coded 8-PSK scheme operating at 4800 b/s is currently under development for use in NASA's Mobile Satellite Experiment (MSAT-X). The author applies the multiple trellis-coded modulation technique in the same fading mobile satellite environment, extending the analysis results previously found for its performance over the AWGN channel to the MSAT-X channel.

Simon, Marvin K.↗

Micro-Scalable Thermal Control Device

A microscalable thermal control module consists of a Stirling cycle cooler that can be manipulated to operate at a selected temperature within the heating and cooling range of the module. The microscalable thermal control module is particularly suited for controlling the temperature of devices that must be maintained at precise temperatures. It is particularly suited for controlling the temperature of devices that need to be alternately heated or cooled. The module contains upper and lower opposing diaphragms, with a regenerator region containing a plurality of regenerators interposed between the diaphragms. Gaps exist on each side of each diaphragm to permit it to oscillate freely. The gap on the interior side one diaphragm is in fluid connection with the gap on the interior side of the other diaphragm through regenerators. As the diaphragms oscillate working gas is forced through the regenerators. The surface area of each regenerator is sufficiently large to effectively transfer thermal energy to and from the working gas as it is passed through them. The phase and amplitude of the oscillations can be manipulated electronically to control the steady state temperature of the active thermal control surface, and to switch the operation of the module from cooling to heating, or vice versa. The ability of the microscalable thermal control module to heat and cool may be enhanced by operating a plurality of modules in series, in parallel, or in connection through a shared bottom layer.

Matthew E. Moran↗

Properties of cerebellar fastigial neurons during translation, rotation, and eye movements

The most medial of the deep cerebellar nuclei, the fastigial nucleus (FN), receives sensory vestibular information and direct inhibition from the cerebellar vermis. We investigated the signal processing in the primate FN by recording single-unit activities during translational motion, rotational motion, and eye movements. Firing rate modulation during horizontal plane translation in the absence of eye movements was observed in all non-eye-movement-sensitive cells and 26% of the pursuit eye-movement-sensitive neurons in the caudal FN. Many non-eye-movement-sensitive cells recorded in the rostral FN of three fascicularis monkeys exhibited convergence of signals from both the otolith organs and the semicircular canals. At low frequencies of translation, the majority of these rostral FN cells changed their firing rates in phase with head velocity rather than linear acceleration. As frequency increased, FN vestibular neurons exhibited a wide range of response dynamics with most cells being characterized by increasing phase leads as a function of frequency. Unlike cells in the vestibular nuclei, none of the rostral FN cells responded to rotational motion alone, without simultaneously exhibiting sensitivity to translational motion. Modulation during earth-horizontal axis rotation was observed in more than half (77%) of the neurons, although with smaller gains than during translation. In contrast, only 47% of the cells changed their firing rates during earth-vertical axis rotations in the absence of a dynamic linear acceleration stimulus. These response properties suggest that the rostral FN represents a main processing center of otolith-driven information for inertial motion detection and spatial orientation.

Non-NASA Center↗

The International Orion Spacecraft Is off Towards the Stars

Following a very successful year of manufacturing, assembly and testing in factories located around the globe, NASA and ESA are preparing to deliver the major Exploration Mission-1 (EM-1) Orion flight elements, including the Crew Module, ESA Service Module and Launch Abort System. This international effort to design and develop a deep space exploration capable human spacecraft is rapidly transitioning from the design, development and test phase to the early test flight and production phase. Two major flight tests, an Ascent Abort test and EM-1, Orion's first flight onboard NASA's new heavy lift Space Launch System, are planned for the near future. Further, Orion will play a crucial role in the ambitious new Deep Space Gateway human exploration Program. This paper gives a short overview of the system and subsystem configuration of the Orion spacecraft, including NASA and ESA contributions, a status of EM-1, AA-2 and EM-2 spacecraft production, and a look at Orion's role in the construction and operation of the Deep Space Gateway. The paper will also address the innovative international cooperation methods being employed to conduct Orion and Service Module integration.

Kirasich, Mark↗

Digital autopilot for the SKYLAB orbital assembly.

In Project SKYLAB, the Command and Service Module which ferries astronaut crews to and from the Orbital Workshop is required to have the capability of providing attitude control for the entire Orbital Assembly during docked phases of the mission. A digital autopilot has been designed which meets this requirement. It is a direct descendant of the digital autopilot designed for and used extensively in project Apollo. There is a major difference however. For Apollo, it was reasonable to design an autopilot that treated the roll, pitch, and yaw axes independently. Because of the geometry of the Orbital Assembly, however, it is of considerable advantage to design the jet selection logic for SKYLAB such that the roll and pitch axes are treated as coupled, and also that the roll and yaw axes are treated as coupled. This paper discusses how inter-axis dependence has been incorporated in the Command and Service Module's digital autopilot while working within the limitations of the onboard computer.

Turnbull, J. F.↗

STS propellant scavenging systems study. Part 2, volume 2: Cost and WBS/dictionary

Presented are the results of the cost analysis performed to update and refine the program phase C/D cost estimates for a Shuttle Derived Vehicle (SDV) tanker. The SDV tanker concept is an unmanned cargo vehicle incorporating a set of propellant tanks in the vehicle's payload module. The tanker will be used to meet the demand for a cryogenic propellant supply in orbit. The propellant tanks are delivered to a low Earth orbit or to an orbit in the vicinity of the Space Station. The intent of the economic analysis is to provide NASA with economic justification for the propellant scavenging concept that minimizes the total Space Transportation System life cycle cost. The detailed costs supporting the concept selection process are presented with descriptive text to aid in forecasting the phase C/D project and program planning. Included are all propellant scavenging costs as well as all SDV, STS and Orbital Maneuvering Vehicle charges to deliver the propellants to the Space Station.

Williams, Frank L.↗

Response of the thermosphere and ionosphere to geomagnetic storms

Four numerical simulations have been performed, at equinox, using a coupled thermosphere-ionosphere model, to illustrate the response of the upper atmosphere to geomagnetic storms. The storms are characterized by an increase in magnetospheric energy input at high latitude for a 12-hour period; each storm commences at a different universal time (UT). The initial response at high latitude is that Joule heating raises the temperature of the upper thermosphere and ion drag drives high-velocity neutral winds. The heat source drives a global wind surge, from both polar regions, which propagates to low latitudes and into the opposite hemisphere. The surge has the character of a large-scale gravity wave with a phase speed of about 600 m/s. Behind the surge a global circulation of magnitude 100 m/s is established at middle latitudes, indicating that the wave and the onset of global circulation are manifestations of the same phenomena. A dominant feature of the response is the penetration of the surge into the opposite hemisphere where it drives poleward winds for a few hours. The global wind surge has a preference for the night sector and for the longitude of the magnetic pole and therefore depends on the UT start time of the storm. A second phase of the meridional circulation develops after the wave interaction but is also restricted, in this case by the buildup of zonal winds via the Coriolis interaction. Conservation of angular momentum may limit the buildup of zonal wind in extreme cases. The divergent wind field drives upwelling and composition change on both height and pressure surfaces. The composition bulge responds to both the background and the storm-induced horizontal winds; it does not simply rotate with Earth. During the storm the disturbance wind modulates the location of the bulge; during the recovery the background winds induce a diurnal variation in its position. Equatorward winds in sunlight produce positive ionospheric changes during the main driving phase of the storm. Negative ionospheric phases are caused by increases of molecular nitrogen in regions of sunlight, the strength of which depends on longitude and the local time of the sector during the storm input. Regions of positive phase in the ionosphere persist in the recovery period due to decreases in mean molecular mass in regions of previous downwelling. Ion density changes, expressed as a ratio of disturbed to quiet values, exhibit a diurnal variation that is driven by the location of the composition bulge; this variation explains the ac component of the local time variation of the observed negative storm phase.

Fuller-Rowell, T. J.↗

Metallic Powder Core Tubular Wire (PCTW) Development for Additive Manufacturing

NASA Langley Research Center (LaRC) in Hampton, VA, and the Center for Welding, Joining, and Coating Research (CWJCR) in the Department of Metallurgical and Materials Engineering at the Colorado School of Mines (CSM) in Golden, CO, have collaborated for nearly fifteen years to develop metallic powder core tubular wire (PCTW) feedstock for additive manufacturing (AM) using electron beam deposition. The motivation for this development was to offset dealloying observed during deposition of titanium and aluminum alloy solid wire feedstock in the LaRC electron beam freeform fabrication (EBF3) system and to explore novel alloy compositions by tailoring the powder fill. EBF3 is a fusion-based AM process that is performed under vacuum and is consequently prone to vaporization loss of low vapor pressure alloying elements. Research spanning four graduate student research projects succeeded in developing the basic methodology to fabricate PCTW, the mass balance equations used to define the powder fill, microstructure control through particulate inoculation, and the feasibility of producing metal matrix composite materials. Metallic PCTW is comprised of a thin foil sheath wrapped around a powder blend. Fabrication of PCTW at CSM was accomplished using a tubular wire mill system to first bend a flat strip into a u-shaped cross section, deposit a powder fill, create a lap joint to seal the wire, and draw to final diameter. Powder management systems were developed to ensure uniform mixing of powder constituents and identify feed rates for optimum fill ratios. Processing parameters were successfully developed for titanium and aluminum alloy sheaths to account for material work hardening during drawing. Mass balance equations were developed to account for compositional contributions of the sheath and powder fill. PCTW composition can be adjusted through selection of the sheath or powder materials. PCTWs were successfully developed to offset Al loss in deposits of Ti-6-4 and Mg loss in Al 6061, resulting in deposits that were within the composition limits for each material. Ti-6-4 deposits were fabricated using PCTW comprised of commercially pure (CP) titanium sheath and a fill of pre-alloyed Ti-6-4 powder with additions of elemental Al and V powders. Additions of both elements were required to account for the CP Ti from the sheath, and Al was further enhanced to offset documented losses in EBF3 deposits. For Al 6061 deposits, composition was modulated through the choice of sheath material. The PCTW was made using an Al 5052 sheath to supplement Mg content and a fill composition of pre-alloyed 6061 powder with additions of Si and Cu.The slower solidification rate of the EBF3 process compared with laser powder bed fusion processes can lead to coarse-grained microstructures and mechanical property anisotropy. EBF3deposits of Ti-6-4 exhibited large epitaxially grown β grains, which result in degraded mechanical properties in the deposition direction. Microstructure refinement was achieved through a combination of electron beam modulation and the use of a PCTW designed for Ti-6-4 deposits and modified by the addition of powder made from Fe and B. Resulting deposits exhibited reductions in β grain size, α phase colony intercept length and lath width, and an increased volume fraction of β phase. The mechanism of microstructure refinement was related to precipitation of boride particles. Hardness testing confirmed that mechanical property anisotropy was reduced and an overall increase in hardness was achieved.Metal matrix composite (MMC) materials offer strength and stiffness benefits over unreinforced materials. Two methods were investigated using PCTW technology for producing Al 6061 basedMMC materials; the direct addition of SiC reinforcing particles and the in-situ generation of reinforcements through reaction synthesis of precursor powders. Al 6061 based MMCs reinforced with SiC exhibited particle clustering and formation of aluminum carbides during deposition. The application of a Ni coating to the SiC particles prior to incorporation into the powder fill eliminated aluminum carbide formation and aided particle distribution during deposition. Modulation of beam focus and power further reduced aluminum carbide formation and aided particle distribution. In reaction synthesis, precursor additions undergo an exothermic reaction during deposition to form new ceramic products, generally of finer scale than the initial precursor components. The product phases provide reinforcement in the MMC and act as nucleation sites during solidification, resulting in grain refinement, improved mechanical properties, and reduced susceptibility to solidification cracking. Higher tensile strength and stiffness were demonstrated in Al 6061 based MMCs with 2 vol% reinforcement. These combined research efforts demonstrate the potential of PCTW technology for customizing of alloy composition and achieving microstructure control. A manufacturing process for titanium- and aluminum-based PCTWs was developed based on iterative design, theoretical calculations, and empirical data. PCTW technology successfully mitigated Al loss from Ti-6-4 and Mg loss in Al 6061, resulted in grain refinement in Ti-6-4, and demonstrated fabrication of Al based MMCs

Marcia S Domack↗

Quiet-time observation of a coherent compressional Pc-4 micropulsation at synchronous altitude

During a magnetically quiet interval the magnetic-field intensity and energetic electron fluxes at ATS 1 exhibited coherent modulations having a frequency of 33.8 cph and a duration of approximately 40 oscillations. The electron fluxes and the magnetic field oscillated in phase. The field perturbation reached 8 jamma (peak to peak) in the direction of the unperturbed geomagnetic field. The transverse component of the field perturbation was practically zero. The characteristics of the observed oscillations appear compatible with those of a compressional excitation of the outer magnetosphere. The substantially radial normal mode is perhaps driven by a bounce-resonant interaction with the 15-keV protons that populate the quiet-day ring current.

Paulikas, G. A.↗

A new device for communication systems

A communication device and modulation capability were developed for the transmission of digital data or voices from point to point. This device is a fast-switching phase coherent frequency synthesizer. When this synthesizer is appropriately incorporated in a communication system it can provide interference resistance, multiple-user capability, user identification, ranging, navigation, Doppler correction, and digitized communication (voice and data). The application of this device to aircraft/airport complex and law enforcement communications is discussed.

Beck, R. R.↗