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At least 1,639 records · Page 91

Three-dimensional Image Fusion Guidance for Transjugular Intrahepatic Portosystemic Shunt Placement

IntroductionTo assess the safety, feasibility and effectiveness of image fusion guidance with pre-procedural portal phase computed tomography with intraprocedural fluoroscopy for transjugular intrahepatic portosystemic shunt (TIPS) placement.Materials and methodsAll consecutive cirrhotic patients presenting at our interventional unit for TIPS creation from January 2015 to January 2016 were prospectively enrolled. Procedures were performed under general anesthesia in an interventional suite equipped with flat panel detector, cone-beam computed tomography (CBCT) and image fusion technique. All TIPSs were placed under image fusion guidance. After hepatic vein catheterization, an unenhanced CBCT acquisition was performed and co-registered with the pre-procedural portal phase CT images. A virtual path between hepatic vein and portal branch was made using the virtual needle path trajectory software. Subsequently, the 3D virtual path was overlaid on 2D fluoroscopy for guidance during portal branch cannulation. Safety, feasibility, effectiveness and per-procedural data were evaluated.ResultsSixteen patients (12 males; median age 56 years) were included. Procedures were technically feasible in 15 of the 16 patients (94%). One procedure was aborted due to hepatic vein catheterization failure related to severe liver distortion. No periprocedural complications occurred within 48 h of the procedure. The median dose-area product was 91 Gy cm{sup 2}, fluoroscopy time 15 min, procedure time 40 min and contrast media consumption 65 mL. Clinical benefit of the TIPS placement was observed in nine patients (56%).ConclusionThis study suggests that 3D image fusion guidance for TIPS is feasible, safe and effective. By identifying virtual needle path, CBCT enables real-time multiplanar guidance and may facilitate TIPS placement.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments

Live-cell imaging has opened an exciting window into the role cellular heterogeneity plays in dynamic, living systems. A major critical challenge for this class of experiments is the problem of image segmentation, or determining which parts of a microscope image correspond to which individual cells. Current approaches require many hours of manual curation and depend on approaches that are difficult to share between labs. They are also unable to robustly segment the cytoplasms of mammalian cells. Here, we show that deep convolutional neural networks, a supervised machine learning method, can solve this challenge for multiple cell types across the domains of life. We demonstrate that this approach can robustly segment fluorescent images of cell nuclei as well as phase images of the cytoplasms of individual bacterial and mammalian cells from phase contrast images without the need for a fluorescent cytoplasmic marker. These networks also enable the simultaneous segmentation and identification of different mammalian cell types grown in co-culture. A quantitative comparison with prior methods demonstrates that convolutional neural networks have improved accuracy and lead to a significant reduction in curation time. We relay our experience in designing and optimizing deep convolutional neural networks for this task and outline several design rules that we found led to robust performance. We conclude that deep convolutional neural networks are an accurate method that require less curation time, are generalizable to a multiplicity of cell types, from bacteria to mammalian cells, and expand live-cell imaging capabilities to include multi-cell type systems.

59 BASIC BIOLOGICAL SCIENCES↗

A thesis on the Development of an Automated SWIFT Edge Detection Algorithm

Throughout the world, scientists and engineers such as those at Los Alamos National Laboratory, perform research and testing unique only to applications aimed towards advancing technology, and understanding the nature of materials. With this testing, comes a need for advanced methods of data acquisition and most importantly, a means of analyzing and extracting the necessary information from such acquired data. In this thesis, I aim to produce an automated method implementing advanced image processing techniques and tools to analyze SWIFT image datasets for Detonator Technology at Los Alamos National Laboratory. Such an effective method for edge detection and point extraction can prove to be advantageous in analyzing such unique datasets and provide for consistency in producing results.

97 MATHEMATICS AND COMPUTING↗

Study of the Internal Compositions of Binary Alloy Pd-Rh Nanoparticles by Using Bragg Coherent Diffraction Imaging

Bragg coherent diffraction imaging (BCDI), a well-established technique for imaging the internal strain of nanoparticles, was used to image the internal compositional distribution of binary alloys in thermal equilibrium. The images experimentally obtained for Pd-Rh alloy nanoparticles are presented and discussed. A direct correspondence between the lattice strain and the compositional deviation is discussed with the derivation of the BCDI displacement field aided by illustrations. The correspondence suggests that the longitudinal derivative of the displacement field, the strain induced by compositional heterogeneity, can be quantitatively converted to 3D images of the compositional deviation from the particle average by using Vegard’s law. It also suggests that the transverse derivative can be qualitatively associated with the disorder of Bragg planes. The studied Pd-Rh alloy nanoparticle exhibited internal composition heterogeneity; the Rh composition tends to be high at edges and corners between facets and gradually decreases from the surface to the core of the particle.

36 MATERIALS SCIENCE↗

Potential of multisensor data and strategies for data acquisition and analysis

Registration and simultaneous analysis of multisensor images is useful because the multiple data sets can be compressed through image processing techniques to facilitate interpretation. This also allows integration of other spatial data sets. Techniques being developed to analyze multisensor images involve comparison of image data with a library of attributes based on physical properties measured by each sensor. This results in the ability to characterize geologic units based on their similarity to the library attributes, as well as discriminate among them. Several studies can provide information on ways to optimize multisensor remote sensing. Continued analyses of the Death Valley and San Rafael Swell data sets can provide insight into tradeoffs in spectral and spatial resolutions of the various sensors used to obtain the coregistered data sets. These include imagery from LANDSAT, SEASAT, HCMM, SIR-A, 11-channel VIS-NIR, thermal inertia images, and aircraft L- and X-band radar.

Evans, D.↗

Analyzing Microchips With Dark-Field Negative Photomicrography

Inverse development process yields fine details. Photomicrographic technique produces images of integrated-circuit chips. Technique based on dark-field illumination: (chip lit with bright central spot of light and photographed by light scattered or diffracted from spot. Reveals more about microstructure patterns related to photoresist masking than more conventional bright-field method.

Suszko, S. F.↗

Bouguer Images of the North American Craton

Processing of existing gravity and aeromagnetic data with modern methods is providing new insights into crustal and mantle structures for large parts of the United States and Canada. More than three-quarters of a million ground station readings of gravity are now available for this region. These data offer a wealth of information on crustal and mantle structures when reduced and displayed as Bouguer anomalies, where lateral variations are controlled by the size, shape and densities of underlying materials. Digital image processing techniques were used to generate Bouguer images that display more of the granularity inherent in the data as compared with existing contour maps. A dominant NW-SE linear trend of highs and lows can be seen extending from South Dakota, through Nebaska, and into Missouri. This trend is probably related to features created during an early and perhaps initial episode of crustal assembly by collisional processes. The younger granitic materials are probably a thin cover over an older crust.

Arvidson, R. E.↗

Automated remote sensing of sea ice using synthetic aperture radar

Two techniques for automated sea ice tracking: image pyramids (hierarchical correlation) and feature tracking were applied to a pair of SEASAT SAR sea ice images. The results compare well with each other and manually tracked estimates of the ice velocity field. Refinement of the image pyramid technique should include removal of a small number of erroneous velocity vectors using constraints dependent on correlation coefficient, near neighbor velocities, and velocity gradients. Estimates of sea ice velocity are successfully obtained over limited areas using the boundary segment tracking technique. Refinement of the feature tracking technique should include use of pressure ridge features, constrained search, and relaxation techniques.

Vesecky, J. F.↗

Planning and executing motions for multibody systems in free-fall

The purpose of this research is to develop an end-to-end system that can be applied to a multibody system in free-fall to analyze its possible motions, save those motions in a database, and design a controller that can execute those motions. A goal is for the process to be highly automated and involve little human intervention. Ideally, the output of the system would be data and algorithms that could be put in ROM to control the multibody system in free-fall. The research applies to more than just robots in space. It applies to any multibody system in free-fall. Mathematical techniques from nonlinear control theory were used to study the nature of the system dynamics and its possible motions. Optimization techniques were applied to plan motions. Image compression techniques were proposed to compress the precomputed motion data for storage. A linearized controller was derived to control the system while it executes preplanned trajectories.

Cameron, Jonathan M.↗

Dual-Mode Combustion of Hydrogen in a Mach 5, Continuous-Flow Facility

Results of an experimental and numerical study of a dual-mode scramjet combustor are reported. The experiment consisted of a direct-connect test of a Mach 2 hydrogen-air combustor with a single unswept-ramp fuel injector. The flow stagnation enthalpy simulated a flight Mach number of 5. Measurements were obtained using conventional wall instrumentation and a particle-imaging laser diagnostic technique. The particle imaging was enabled through the development of a new apparatus for seeding fine silicon dioxide particles into the combustor fuel stream. Numerical simulations of the combustor were performed using the GASP code. The modeling, and much of the experimental work, focused on the supersonic combustion mode. Reasonable agreement was observed between experimental and numerical wall pressure distributions. However, the numerical model was unable to predict accurately the effects of combustion on the fuel plume size, penetration, shape, and axial growth.

Goyne, C. P.↗

Multi-Wavelength Comparison of Jupiter’s Zonal Winds During the New Horizons and Cassini Flybys

We present Jovian zonal wind speeds measured during the Cassini and New Horizons Jupiter flybys in 2000 and 2007, respectively. We performed our cloud tracking wind measurements using an automated, two-dimensional correlation imaging velocimetry technique. We analyzed all LORRI panchromatic images from the New Horizons Jupiter flyby dataset. This LORRI measurement documents the state of Jupiter’s zonal mean wind speed in 2007 and extends the historical record of Jupiter’s winds that serve as useful points of comparison for Juno observations. Among the Cassini ISS images, we analyzed the CL1CL2, CB2, UV3, BL1, BL2, GRN, RED, IR1, IR2, IR3, IR4, MT2, and MT3 filters. Our Cassini measurements provide valuable context to understand the altitudes probed by LORRI. Comparing the panchromatic LORRI measurements against past wind measurements using images captured with various narrow and wide-band camera filters is not straightforward. Because the Cassini ISS CL1CL2 “clear” filter’s performance is similar to that of LORRI, comparing CL1CL2 winds against LORRI results will help determine if the New Horizons measurements represent Jupiter’s cloud-top zonal wind speeds or if they are sensitive to different altitudes. In addition to placing our New Horizons measurements in altitudinal context, the Cassini ISS's IR4, IR2, RED, GRN, and BL1 filters are similar to those on Europa Clipper EIS camera. Wind measurements performed using those ISS filters will enable comparison to future missions, including anticipated observations to be taken by Europa Clipper.

Jupiter↗

Preparing for Europa Clipper Jupiter Observations: Multi-Wavelength Zonal Winds During the New Horizons and Cassini Flybys

We present Jovian zonal wind speeds measured during the Cassini and New Horizons Jupiter flybys in 2000 and 2007, respectively. We performed our cloud tracking wind measurements using an automated, two-dimensional correlation imaging velocimetry technique. We analyzed all LORRI panchromatic images from the New Horizons Jupiter flyby dataset. This LORRI measurement documents the state of Jupiter’s zonal mean wind speed in 2007 and extends the historical record of Jupiter’s winds. Among the Cassini ISS images, we processed the CL1CL2, CB2, UV3, BL1, BL2, GRN, RED, IR1, IR2, IR3, IR4, MT2, and MT3 filters. Our Cassini measurements provide valuable context to understand the altitudes probed by LORRI. Comparing the panchromatic LORRI measurements against past wind measurements using images captured with various narrow and wide-band camera filters is not straightforward. Because the Cassini ISS CL1CL2 “clear” filter’s performance is similar to that of LORRI, comparing CL1CL2 winds against LORRI results will help determine if the New Horizons measurements represent Jupiter’s cloud-top zonal wind speeds or if they are sensitive to different altitudes. In addition to placing our New Horizons measurements in altitudinal context, the Cassini ISS's IR4, IR2, RED, GRN, and BL1 filters are similar to those on Europa Clipper EIS camera. Wind measurements performed using those ISS filters will enable comparison to future missions, including anticipated observations to be taken by Europa Clipper

Jupiter↗

Machine Learning in Multimodal Medical Imaging

Machine learning techniques have been increasingly applied in the medical imaging field for developing computer-aided diagnosis and prognosis models. Multimodal medical imaging can provide us with separate yet complementary structure and function information of a patient study and hence has transformed the way we study living bodies. Therefore, using machine learning techniques to deal with multimodal medical images is much more challenging due to the diversity of biophysical-biochemical mechanisms. In these years, researchers mainly adapt modern machine learning and pattern recognition techniques such as supervised, unsupervised, semi-supervised, and deep learning to solve multimodal medical imaging related problems.

60 APPLIED LIFE SCIENCES↗

Multimode turbulent flow measurements using magnetic resonance imaging- and laser-based techniques and computational fluid dynamics simulations

We studied the flow field characteristics of a turbulent flow over a regularized cube array with a perpendicular injection flow through the floor between the second and third cubical elements, representing the complex flow interactions of a 3D jet and the wake flows behind cubical obstacles. Four different experimental measurements were performed: two magnetic resonance imaging-based measurements for three-dimensional three-component velocity (MRV) and concentration (MRC) and two laser-based techniques, particle image velocimetry (PIV) and planar laser-induced fluorescence (PLIF), for two-dimensional two-component velocity and concentration measurement, respectively. The mainstream Reynolds number is Re = 15 000⁠, based on the primary inlet velocity U m and channel height D H ⁠, whereas the injector Reynolds number is Re j = 3400⁠, based on the injector velocity U j and the injector's exit width D j ⁠. Numerical simulations were performed for the studied flow configuration of turbulent flow over a regularized cube array using Reynolds-averaged Navier–Stokes (RANS) and large-eddy simulation (LES) approaches. Results obtained from experimental measurements—including MRV, MRC, PIV, and PLIF—as well as RANS and LES simulations are discussed and compared along several horizontal and vertical planes of the studied configuration. In addition, 3D turbulent flow structures, such as leading-edge vortex, horseshoe vortex, and jet shear-layer vortex, and the isosurfaces of scalar concentration successfully revealed by MRV and MRC techniques were found to be in very good agreement with those 3D features extracted from RANS and LES simulations. In conclusion, the high-resolution experimental and numerical database obtained from this study could be useful for validation and verification of numerical codes.

Computational fluid dynamics↗

High resolution dual detector volume-of-interest cone beam breast CT - Demonstration with a bench top system

Purpose: In this study, we used a small field high resolution detector in conjunction with a full field flat panel detector to implement and investigate the dual detector volume-of-interest (VOI) cone beam breast computed tomography (CBCT) technique on a bench-top system. The potential of using this technique to image small calcifications without increasing the overall dose to the breast was demonstrated. Significant reduction of scatter components in the high resolution projection image data of the VOI was also shown. Methods: With the regular flat panel based CBCT technique, exposures were made at 80 kVp to generate an air kerma of 6 mGys at the isocenter. With the dual detector VOI CBCT technique, a high resolution small field CMOS detector was used to scan a cylindrical VOI (2.5 cm in diameter and height, 4.5 cm off-center) with collimated x-rays at four times of regular exposure level. A flat panel detector was used for full field scan with low x-ray exposures at half of the regular exposure level. The low exposure full field image data were used to fill in the truncated space in the VOI scan data and generate a complete projection image set. The Feldkamp-Davis-Kress (FDK) filtered backprojection algorithm was used to reconstruct high resolution images for the VOI. Two scanning techniques, one breast centered and the other VOI centered, were implemented and investigated. Paraffin cylinders with embedded thin aluminum (Al) wires were imaged and used in conjunction with optically stimulated luminescence (OSL) dose measurements to demonstrate the ability of this technique to image small calcifications without increasing the mean glandular dose (MGD). Results: Using exposures that produce an air kerma of 6 mGys at the isocenter, the regular CBCT technique was able to resolve the cross-sections of Al wires as thin as 254 {mu}m in diameter in the phantom. For the specific VOI studied, by increasing the exposure level by a factor of 4 for the VOI scan and reducing the exposure level by a factor of 2 for the full filed scan, the dual-detector CBCT technique was able to resolve the cross-sections of Al wires as thin as 152 {mu}m in diameter. The CNR evaluated for the entire Al wire cross-section was found to be improved from 5.5 in regular CBCT to 14.4 and 16.8 with the breast centered and VOI centered scanning techniques, respectively. Even inside VOI center, the VOI scan resulted in significant dose saving with the dose reduced by a factor of 1.6 at the VOI center. Dose saving outside the VOI was substantial with the dose reduced by a factor of 7.3 and 7.8 at the breast center for the breast centered and VOI centered scans, respectively, when compared to full field scan at the same exposure level. The differences between the two dual detector techniques in terms of dose saving and scatter reduction were small with VOI scan at 4x exposure level and full field scan at 0.5x exposure level. The MGDs were only 94% of that from the regular CBCT scan. Conclusions: For the specific VOI studied, the dual detector VOI CBCT technique has the potential to provide high quality images inside the VOI with MGD similar to or even lower than that of full field breast CBCT. It was also found that our results were compromised by the use of inadequate detectors for the VOI scan. An appropriately selected detector would better optimize the image quality improvement that can be achieved with the VOI CBCT technique.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Association of American Geographers, Remote Sensing Specialty Group Special Issue of Geocarto International

This special issue continues the precedence of the Association of American Geographers (AAG), Remote Sensing Specialty Group (RSSG) for publishing selected articles in Geocarto International as a by-product from the AAG annual meeting. As editors, we issued earlier this year, a solicitation for papers to be published in a special issue of Geocarto International that were presented in RSSG-sponsored sessions at the 2001 AAG annual meeting held in New York City on February 27-March 3. Although not an absolute requisite for publication, the vast majority of the papers in this special issue were presented at this year's AAG meeting in New York. Other articles in this issue that were not part of a paper or poster session at the 2001 AAG meeting are authored by RSSG members. Under the auspices of the RSSG, this special Geocarto International issue provides even more compelling evidence of the inextricable linkage between remote sensing and geography. The papers in this special issue fall into four general themes: 1) Urban Analysis and Techniques for Urban Analysis; 2) Land Use/Land Cover Analysis; 3) Fire Modeling Assessment; and 4) Techniques. The first four papers herein are concerned with the use of remote sensing for analysis of urban areas, and with use or development of techniques to better characterize urban areas using remote sensing data. As the lead paper in this grouping, Rashed et al., examine the usage of spectral mixture analysis (SMA) for analyzing satellite imagery of urban areas as opposed to more 'standard' methods of classification. Here SMA has been applied to IRS-1C satellite multispectral imagery to extract measures that better describe the 'anatomy' of the greater Cairo, Egypt region. Following this paper, Weng and Lo describe how Landsat TM data have been used to monitor land cover types and to estimate biomass parameters within an urban environment. The research reported in this paper applies an integrated GIS (Geographic Information System) approach for detecting urban growth and assessing its impact on biomass in the Zhujiang Delta, China. The remaining two papers in this first grouping deal with improved techniques for characterizing and analyzing urban areas using remote sensing data. Myint examines the use of texture analysis to better classify urban features. Here wavelet analysis has been employed to assist in deriving a more robust classification of the urban environment from high spatial resolution, multispectral aircraft data. Mesev provides insight on how through the modification of the standard maximum likelihood image analysis technique, population census data can be used enhance the overall robustness of urban image classification through the modification of the standard maximum likelihood image analysis technique.

Allen, Thomas R.↗

SU-G-TeP4-03: A Multileaf Collimator Calibration and Quality Assurance Technique Using An Electronic Portal Imaging Device

Purpose: To develop an accurate and quick multileaf collimator (MLC) calibration and quality assurance technique using an electronic portal imaging device (EPID) Methods: The MLC models used include the MLCi and Agility (Elekta Ltd). This technique consists of two 22(L)x10(W) cm{sup 2} fields with 0{sup 0} and 180{sup 0} collimator angles centered to an offset EPID. The MLC opening is estimated by calculating the profile at the image’s center in the image’s horizontal direction. Scans in the image’s vertical direction were calculated every 20 pixels in the inner 70% of estimated MLC opening. The profiles’ edges were fitted with linear equations to determine the image’s rotation angle. Then, crossline profiles were scanned at the center of each leaf taking into account the leaf’s width at isocenter and the rotation angle. The profiles’ edges determine the location of the leaves’ edges and these were subtracted from the reference leaf’s position in order to determine the relative leaf offsets. The edge location of all profiles was determined by using the parameterized gradient of the penumbra region. The technique was tested against an established diode array-based method, and for different MLC systems, patterns, gantry angles, days, energies, beam modalities and MLC openings. Results: The differences between the proposed and established methods were 0.26±0.19mm. The leaf offsets’ deviation was <0.3mm (5 months period). For pattern fields, the differences between predetermined and calculated offsets were 0.18±0.18mm. The leaf offset deviation of measurements with different energies and MLC openings were <0.1mm and <0.3mm, respectively. The differences between offsets of FF and FFF beams were 0.01±0.02mm (<0.07mm). The differences between the offsets at different gantry angles were 0.08±0.15mm. Conclusion: The proposed method proved to be accurate and efficient in calculating the relative leaf offsets. Parameterized field edge is essential to obtain accurate result by eliminating the noise from EPID.

60 APPLIED LIFE SCIENCES↗

Enhancement of digital images through band ratio techniques for geological applications

The fundamentals in the use of band ratio techniques to enhance spectral signatures of geologic interest are discussed. The path radiance, additive term of the measured radiance at any given wavelength, is almost completely eliminated from LANDSAT images by subtracting the smallest value of the radiance measured in each channel, at shadows caused by topographic relief and clouds, and deep clear water bodies. By ratioing successive spectral channels the effect of solar angle of elevation is minimized and the product expresses, to a first approximation, a relationship between reflectances, which are intrinsic characteristics of the targets. Ratios between noncorrelated channels, such as R 7/4, R 7/5, and R 6/4 are useful to show variations in the vegetation cover, probably related to geobotanical associations.

Filho, R. A.↗