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At least 1,621 records · Page 90

DNA Methylation Detection Using Resonance and Nanobowtie-Antenna-Enhanced Raman Spectroscopy

In this paper, we show that DNA carrying 5-methylcytosine modifications or methylated DNA (m-DNA) can be distinguished from DNA with unmodified cytosine by Raman spectroscopy enhanced by both a bowtie nanoantenna and excitation resonance. In particular, m-DNA can be identified by a peak near 1000 cm -1 and changes in the Raman peaks in the 1200–1700 cm -1 band that are enhanced by the ring-absorption resonance. The identification is robust to the use of resonance Raman and nanoantenna excitation used to obtain significant signal improvement. The primary differences are three additional Raman peaks with methylation at 1014, 1239, and 1639 cm -1 and spectral intensity inversion at 1324 (C 5 =C 6 ) and 1473 cm -1 (C 4 =N 3 ) in m-DNA compared to that of DNA with unmodified cytosine. We attribute this to the proximity of the methyl group to the antenna, which brings the (C 5 =C 6 ) mode closer to experiencing a stronger near-field enhancement. We also show distinct Raman spectral features attributed to the transition of DNA from a hydrated state, when dissolved, to a dried/denatured state. We observe a general broadening of the larger lines and a transfer of spectral weight from the ~1470 cm -1 vibration to the two higher-energy lines of the dried m-DNA solution. We attribute the new spectral characteristics to DNA softening under high salt conditions and find that the m-DNA is still distinguishable via the ~1000 cm -1 peak and distribution of the signal in the 1200–1700 cm -1 band. The nanoantenna gain exceeds 20,000, whereas the real signal ratio is much less because of a low average enhanced region occupancy even with these relatively high DNA concentrations. It is improved when fixed DNA in a salt crystal lies near the nanoantenna. Finally, the Raman resonance gain profile is consistent with A-term expectations, and the resonance is found at ~259 nm excitation wavelength.

59 BASIC BIOLOGICAL SCIENCES↗

Correlated particle transport enables biological free energy transduction

Studies of biological transport frequently neglect the explicit statistical correlations among particle site occupancies (i.e., they use a mean-field approximation). Neglecting correlations sometimes captures biological function, even for out-of-equilibrium and interacting systems. Here, we show that neglecting correlations fails to describe free energy transduction, mistakenly predicting an abundance of slippage and energy dissipation, even for networks that are near reversible and lack interactions among particle sites. Interestingly, linear charge transport chains are well described without including correlations, even for networks that are driven and include site-site interactions typical of biological electron transfer chains. We examine three specific bioenergetic networks: a linear electron transfer chain (as found in bacterial nanowires), a near-reversible electron bifurcation network (as in complex III of respiration and other recently discovered structures), and a redox-coupled proton pump (as in complex IV of respiration).

bacterial nanowires↗

Measured daylighting potential of a static optical louver system under real sun and sky conditions

Side-by-side comparisons were made over solstice-to-solstice changes in sun and sky conditions between an optical louver system (OLS) and a conventional Venetian blind set at a horizontal slat angle and located inboard of a south-facing, small-area, clerestory window in a full-scale office testbed. Daylight autonomy (DA), window luminance, and ceiling luminance uniformity were used to assess performance. The performance of both systems was found to have significant seasonal variation, where performance under clear sky conditions improved as maximum solar altitude angles transitioned from solstice to equinox. Although the OLS produced fewer hours per day of DA on average than the Venetian blind, the OLS never exceeded the designated 2000 cd/m2 threshold for window glare. In contrast, the Venetian blind was found to exceed the visual discomfort threshold over a large fraction of the day during equinox conditions. Notably, these peak periods of visual discomfort occurred during the best periods of daylighting performance. Luminance uniformity was analyzed using calibrated high dynamic range luminance images. Under clear sky conditions, the OLS was found to increase the luminance of the ceiling as well as produce a more uniform distribution. Furthermore, compared to conventional venetian blinds, the static optical sunlight redirecting system studied has the potential to significantly reduce the annual electrical lighting energy demand of a daylit space and improve the quality from the perspective of building occupants by consistently transmitting useful daylight while eliminating window glare.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Cooling efficiency of a spot-type personalized air-conditioner

Here, this study defined Cooling Efficiency ( CE ) of a Spot-type Personalized Air-Conditioning (SPAC) device as the ratio of the additional sensible heat removal from human body induced by SPAC and the device's cooling capacity. CE enabled the investigation of SPAC performance on the occupant's sensible heat loss (Q s ) and thermal sensation by its quantitative relation with the change of PMV level ( ΔPMV ). Three round nozzles with the diameter of 0.08 m, 0.105 m, and 0.128 m, respectively, discharged air jets at airflow rates from 11.8 L s –1 to 59.0 L s –1 , toward the chest of a seated or standing human body with a clothing of 0.48 clo. This study developed a validated CFD model coupled with the Fanger's thermoregulation model, to calculate Q s in a room of 26 °C ventilated at a rate of 3 ACH. According to the results, Q s , CE and draft risk ( DR ) at face had significant positive linear correlation with the SPAC device's supply airflow rates (R2 >0.96), and a negative linear correlation for ΔPMV. With DR = 20% at face, CE was always under 0.3, and ΔPMV was around -1.0–1.1. Interestingly, both CE and ΔPMV had the least favorable values for the air jet produced by the nozzle with the diameter of 0.105 m independent of body posture. In conclusion, although SPAC could lead to additional Q s by sending air at a higher airflow rate from a smaller nozzle, the improvement in cooling efficiency and thermal sensation had a limit due to draft risk.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Micro-environmental control for efficient local heating: CFD simulation and manikin test verification

Micro-environment control system has been proved to be able to provide local thermal comfort control. It also has the potential to save building energy by relaxing the control on the unoccupied space. This work aims at designing an efficient heating delivering device (HDD) to locally warm the person to restore thermal comfort when the unoccupied space temperature is reduced from 70.0 °F to 66.0 °F to save the energy. A three-stage approach was developed for designing the HDD including the initial stage of developing by CFD simulation, the second stage of manikin test verification and final stage of human subject test confirmation. The results of the first two stages were presented and discussed in this work. It was shown that convective heating was not efficient enough unless a confinement box was used to hold the hot air around the legs and feet. A more ergonomically friendly design of using a foot warmer was finally proved to be a better solution for individually heating by both simulation and experiments since it can heat the occupant sufficiently. The ability of using CFD to predict heat loss from the clothed human body and its limitation was also investigated. It was found that with proper clothing insulation, the CFD can give a reasonable prediction, although simulating the clothing as a layer of certain thermal resistance might be problematic regarding the structure and permeability of the clothing material. In conclusion, a more appropriate method for simulating the clothing was needed for better prediction in the future.

42 ENGINEERING↗

Review of thermal comfort infused with the latest big data and modeling progresses in public health

Thermal environment is important for both occupants’ comfort and health. Previously, the impacts of thermal environment were explored in the areas of thermal comfort and public health separately. This paper aims to bridge both disciplines by examining the correlation between comfort temperature and Minimum Mortality Temperature (MMT), which is a key index quantifying the association of health and weather temperature, through literature review and data-driven approach. It was found that the MMT data obtained from the public health area are generally in good agreement with the thermal neutral temperatures from the comfort perspective. The MMT data range from 17.2 °C to 30 °C, which are similar to the thermal neutral temperatures ranging from 19.5 °C to 30 °C based on the global field tests. Moreover, the MMT data demonstrate the potential to capture some complex distribution patterns of the field comfort data. The introduction of the health-temperature data could assist the intensive field experiments and modeling efforts and complement the thermal comfort dataset, which suffers from the problems of limited sample size. Some discrepancies between the two datasets were identified as well. The contextual factors other than the climate factor which may cause such discrepancies, such as socio-economics, population densities, etc. should be analyzed to enable the potential application of the health-temperature data and modeling to thermal comfort and health studies.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

High-density thermal sensitivity maps of the human body

‘Personal comfort systems’ and thermally active clothing are able to warm and cool individual building occupants by transferring heat directly to and from their body surfaces. Such systems would ideally target local body surfaces with high temperature sensitivities. Such sensitivities have not been quantified in detail before. Here we report local thermal sensations and sensitivities for 318 local skin spots distributed over one side of the body, measured on a large number of subjects. Skin temperature changes were induced with a thermal probe 14 mm in diameter, and subjective thermal sensations were surveyed after 10 s. Our neutral base temperature was 31 °C and the spot stimulus was ±5 °C. Cool and warm sensitivities are seen to vary widely by body part. The foot, lower leg and upper chest are much less sensitive than average; in comparison, the cheek, neck back, and seat area are 2–3 times as sensitive to both cooling and warming stimuli. Every body part exhibits stronger sensitivity to cooling (1.3–1.6 times stronger) than to warming. Inter-personal differences and regional variance within body parts were observed to be 2–3 times greater than potential sex differences. These high-density thermal sensitivity maps with appended dataset provide the most comprehensive distributions of cold and warm sensitivity across the human body.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

A simulation-based assessment of technologies to reduce heat emissions from buildings

Heat emissions from buildings are part of anthropogenic heat leading to urban overheating. This paper aims to assess how technologies (i.e., energy conservation measures - ECMs), used to decrease energy use, may also reduce heat emissions from buildings. This study employs the physics-based engine EnergyPlus to simulate the main components of heat emissions from buildings to ambient air: envelope, zone, and systems. Hourly simulations are run for IECC single- and multi-family reference models with three representative climates: Miami, Baltimore, and Chicago. The results show that the performance of ECMs varies among weather, seasons, and residential typologies. Particularly, some ECMs (i.e., cool coatings, heat pumps, additional insulation, energy-awareness occupants) show a strong decrease in heat emissions, yet they are not always correlated with proportional decreases in energy use. When all ECMs are combined, the reductions are larger on heat emissions (89%) than on site energy (65%) from the base cases. During summer in Miami, the combination of ECMs shows a decrease in heat emissions from the building surface component of 80% during daytime, 92% for the HVAC component and a counterbalanced increase in the zone component of 88%, bringing to a daily decrease in total heat emissions. The main contributions of this study are quantifying how typical ECMs influence residential building heat emissions using EnergyPlus simulations and informing urban planners and stakeholders on prioritizing measures for mitigating urban overheating problems.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Investigation of pre-cooling as a recommended measure to improve residential buildings’ thermal resilience during heat waves

More intense heat waves are expected to occur more frequently in the twenty-first century. During severe heat waves, cooling capacity shortfall and overheating are likely to occur in residential buildings, and this will adversely affect occupant's thermal comfort and productivity. We propose a strategy of pre-cooling the house during off-peak hours to mitigate overheating during heat waves. Additionally, simulation results of a prototype single-family house show that adopting the rule-based control (RBC) of pre-cooling thermostat setpoint schedule is effective in reducing thermal discomfort, and that the efficacy of pre-cooling depends upon several building characteristics. An optimized control (OC) of the thermostat setpoint schedule was developed based on the simulation of a prototype building. A simplified yet improved RBC (IRBC) pre-cooling schedule was then extracted from the OC schedule for practical implementation at a larger scale. The effects of the RBC schedule and IRBC schedule were evaluated in the King District of Fresno, which contains 814 residential buildings. Results show that both thermostat setpoint schedules can reduce overheating effectively and that IRBC is slightly better than RBC for most buildings. The findings support the California government's recommendation on pre-cooling to mitigate overheating, which can be further improved with an optimized thermostat setpoint schedule broadcast to residents through early alert messages before a heat wave.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

From fault-detection to automated fault correction: A field study

A fault detection and diagnostics (FDD) tool, as addressed by this study, is a tool that continuously identifies the presence of faults and efficiency improvement opportunities through a one-way interface to the building automation system and the application of automated analytics. Although FDD tools can inform operators of building operational faults, currently an action is always required to correct the faults to generate energy savings. Fault auto-correction integrating with commercial FDD technology offerings can close the loop between the passive diagnostics and active control, increase the savings generated by FDD tools, and reduce the reliance on human intervention. This paper presents the field study of seven fault auto-correction algorithms implemented in commercial FDD platforms. Implementation includes software changes in the FDD tools and additional controls hardware or software changes in the BAS that were required to enable the execution of different types of auto-correction algorithms in real buildings. The routines successfully and automatically correct faults and improve the operation of large built-up Heating, Ventilation, and Air Conditioning (HVAC) systems, common in most commercial buildings. The auto-correction algorithms are tested across four buildings and three different building automation systems, following a rigorous procedure to make sure they work properly and do not negatively impact the system and building occupants. Finally, technology benefits, market drivers, and scalability changes are drawn from the implementation effort and test results, to drive future research and industry engagement.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Assessing thermal resilience of an assisted living facility during heat waves and cold snaps with power outages

Extreme hot and cold weather events are becoming more frequent, intense, and longer due to climate change. When these events occur coincidentally with power outages, the resulting extreme indoor temperatures pose a severe health hazard for occupants. This study conducted a holistic modeling and analysis of an assisted living facility, where senior residents live, to assess its thermal resilience performance under a six-day heat wave in 2015 and a three-day cold snap in 2021 with power outages. Impacts of 13 energy efficiency measures on thermal resilience and backup power capacity of the facility were evaluated. Three thermal resilience metrics: the SET (standard effective temperature) degree-hours, the Heat Index, and the Hours of Safety, were used and calculated from the EnergyPlus simulation models. Furthermore, major findings are: (1) the facility would suffer from extreme temperatures during the cold and hot events without a power supply, not meeting the passive survivability requirements; (2) most passive envelope measures improve thermal resilience for both hot and cold events, but making the building envelope airtight results in conflicting performance between the hot and cold events; (3) natural ventilation is an effective measure to mitigate summer indoor overheating; and (4) the energy efficiency package can reduce backup power capacity by 19% for the three-day cold snap. It is recommended that building technologies and design strategies be evaluated to consider co-benefits of energy use, thermal resilience, and backup power needs through building energy codes or policies for existing and new buildings, which are transitioning for decarbonization and climate resilience.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Ten questions concerning reinforcement learning for building energy management

As buildings account for approximately 40% of global energy consumption and associated greenhouse gas emissions, their role in decarbonizing the power grid is crucial. The increased integration of variable energy sources, such as renewables, introduces uncertainties and unprecedented flexibilities, necessitating buildings to adapt their energy demand to enhance grid resiliency. Consequently, buildings must transition from passive energy consumers to active grid assets, providing demand flexibility and energy elasticity while maintaining occupant comfort and health. This fundamental shift demands advanced optimal control methods to manage escalating energy demand and avert power outages. Reinforcement learning (RL) emerges as a promising method to address these challenges. Here, in this paper, we explore ten questions related to the application of RL in buildings, specifically targeting flexible energy management. We consider the growing availability of data, advancements in machine learning algorithms, open-source tools, and the practical deployment aspects associated with software and hardware requirements. Our objective is to deliver a comprehensive introduction to RL, present an overview of existing research and accomplishments, underscore the challenges and opportunities, and propose potential future research directions to expedite the adoption of RL for building energy management.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Air quality and comfort constrained energy efficient operation of multi-zone buildings

Maintaining indoor air quality (IAQ) through effective ventilation is essential for the well-being and productivity of building occupants. Control strategies aimed at improving the efficiency of heating, ventilation and air conditioning (HVAC) systems must jointly determine ventilation and heating and cooling processes. Here, in this paper, we study the problem of minimizing the energy consumption of the HVAC system in a multi-zone building, while meeting thermal comfort and IAQ requirements. We first perform a steady state analysis of the zonal carbon dioxide (CO 2 ) concentration and the temperature dynamics. The resulting expressions are convex in the zonal mass flow rates and zonal temperatures. Guided by the steady state solutions for meeting the thermal comfort constraints, we develop two control policies for improving the energy efficiency of building HVAC systems while jointly satisfying indoor temperature and IAQ constraints. We compare the performance of our proposed approaches with those of multiple baseline approaches which implement separate regimes for controlling zonal temperature and IAQ for a typical work-day in a multi-zone campus building. We have evaluated the performance of our proposed approaches under varying levels of flexibility in zonal temperatures. We have shown that zonal temperature flexibility can result in energy savings up to 32% (for the same control strategies) as compared to the case where no such flexibility is permitted. Our proposed approaches were seen to offer potential savings of nearly 29% compared to the baseline.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Benefits assessment of cool skin and ventilated cavity skin: Saving energy and mitigating heat and grid stress

This study assessed the energy-saving and climate-adaptive potential of cool skin and ventilated cavity skin facade technologies in Seoul's high-rise apartment buildings. We created weather scenarios for historical, mid-term future, and long-term future conditions using Coordinated Regional Downscaling EXperiment (CORDEX) method. Building energy simulations were conducted on a South Korean high-rise apartment model to evaluate their performance under different weather conditions. The results indicate that cool skin and ventilated cavity skin technologies can save cooling energy during summers but lead to heating energy penalties in winters. Ventilated cavity skin outperforms cool skin, offering better cooling energy savings and reduced heating penalties. Combining both technologies yields the highest overall energy savings, with 7 %, 9 %, and 10 % cooling energy savings for cool skin, ventilated cavity skin, and the combined package, respectively. However, cool skin increases heating energy consumption by 5 %, while ventilated cavity skin has minimal impact on heating energy. These envelope technologies also reduce peak electricity demand by at least 5 %, 8 %, and 9 %, respectively. They contribute to heat stress reduction, enhance resilience, and decrease extreme heat risks for occupants during power outages by at least 18 % under various weather conditions. Considering the prevalence of aging high-rise apartments in South Korea, adopting these envelope renovation strategies can effectively reduce cooling loads, enhance thermal comfort, and boost resilience under future climates, while avoiding costly reconstruction.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

The health and indoor environmental quality impacts of residential building envelope retrofits: A literature review

Retrofitting existing buildings to improve energy efficiency is an important strategy to meet increasingly stringent energy efficiency targets. While the primary objective of energy efficiency retrofits is to reduce energy consumption and greenhouse gas emissions, retrofits can also result in non-energy impacts (NEIs), which contribute to decision-making processes and overall value of the retrofit. NEIs have been studied extensively in retrofitted residential buildings; however, these studies have historically grouped passive (i.e., building envelope) and active (i.e., heating, ventilation, and air conditioning (HVAC) and energy system) upgrades, making it difficult to identify the underlying mechanism(s) of action for each NEI and developing effective retrofit strategies, based on occupant need. The purpose of this study was to better account for NEIs, based on a literature review, summarizing the current state of knowledge on NEIs associated with residential building envelope retrofits. We limited our search to health- and indoor environmental quality-related NEIs. The review identified strong evidence that building envelope retrofits improve acoustic comfort, wintertime thermal comfort, and respiratory and cardiovascular health outcomes. IAQ outcomes were mixed, with studies reporting both increases and decreases to indoor contaminant concentrations following retrofits. The strength of the effect was generally governed by pre-retrofit contaminant concentrations and whether indoor concentrations were dominated by indoor or outdoor sources. Most studies evaluating summertime thermal comfort identified increased incidence of summertime overheating; however, none of these studies linked the change in thermal conditions to health outcomes. Recommendations for future work include expanding studies to include more market rate housing and the health impacts of summertime overheating in retrofitted buildings.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Ten questions concerning housing sufficiency

Housing sufficiency is an emerging concept in the provision of environmentally sustainable housing. It aims for demand-side strategies that reduce excessive, aggregate consumption levels to promote efficient resource utilization and sustainability in the construction sector while providing everyone with a decent standard of housing. However, it is challenging to implement as it interferes with housing-related social and cultural norms. This paper poses and answers ten questions that highlight the challenges, opportunities, and examples of sufficiency strategies in the context of housing provision and the environmental crisis. Question 1 discusses the need for sufficiency as a tool to complement supply-side strategies including efficiency and renewable energy strategies in providing housing. Question 2 examines the concept of housing sufficiency from different perspectives, such as ecological economics and social ecology. Question 3 summarizes the methods used to measure housing sufficiency, with specific focus on the upper and lower limits that respect planetary boundaries and basic human needs. Questions 4 and 5 describe the benefits, potential drawbacks, and rebound effects of housing sufficiency. Questions 6 and 7 examine housing sufficiency in developed and developing countries, respectively. Questions 8 and 9 discuss design strategies, housing occupancy, and tenure models that are needed for housing sufficiency. Finally, Question 10 provides a of policies and regulations that are needed to systematically support the implementation of sufficiency strategies. The questions and answers provide insights for wider application of housing sufficiency in research and practice.

Arceo, Aldrick↗

Ten questions on building stock modeling to inform energy efficiency and sustainability

To enhance economic competitiveness and ensure energy efficiency, resilience, and security, cities and governments are adopting technologies and strategies to improve their existing building stocks. This approach aims to reduce energy use, improve energy affordability, and ensure a reliable power supply while safeguarding occupants during extreme weather events that may disrupt energy services. The effectiveness of these solutions will depend on building stock characteristics, use patterns, weather conditions, evolving technologies and their markets, and a city’s socio-economic conditions. This paper presents ten questions and answers that highlight the most important issues regarding the use of building stock modeling as a powerful tool to provide insights for informing stakeholders’ actions and decision-making on energy efficiency, costs reduction, and resilience of buildings in cities. Building stock modeling should build upon the fit-for-purpose framework, balancing the use case accuracy requirements, level of complexity, and needed resources (expertise, compute). The advancements in Artificial Intelligence (AI), the increasingly available open dataset of building stock in cities, and the more affordable powerful computing will accelerate the adoption of building stock modeling across scales by researchers and practitioners to inform decision making on sustainability and efficiency.

AI↗

Analysis of strategies to meet ASHRAE S241 infectious aerosol control targets by space type and region using EnergyPlus™ simulations

Professional organizations, such as ASHRAE, have recently proposed new voluntary standards for controlling infectious aerosols. Specifically, ASHRAE Standard 241 (S241) defines equivalent clean air targets for a range of space types that can be met through combinations of mitigation measures. This paper seeks to inform the selection of measures by space type and climate zone through building simulations that quantify the impacts of increased outdoor air ventilation; increasing filtration and/or adding germicidal ultraviolet (GUV) in the central heating, ventilation, and air-conditioning (HVAC) systems; or using portable air cleaners (PACs), upper room GUV, or whole room GUV approaches to increase equivalent clean air delivery. The measures are assessed individually and in practical combinations for their ability to meet S241 in four space types (offices, classrooms, dining areas, and healthcare waiting rooms) using prototype buildings modeled using EnergyPlus. The mitigation measures are compared holistically against baseline building operations using metrics for equivalent clean air, energy, and comfort. The results in this study show that single measures can meet S241 for offices with minimal impacts on energy and comfort, while either upper room GUV systems or combinations of measures such as MERV 13 HVAC filtration with PACs are needed to meet S241 for classrooms. The dining area and healthcare waiting room targets cannot be met in this study when assuming design occupancy and MS2 as the challenge agent, even when combining multiple measures together. This paper provides valuable considerations when designing measures to meet S241 for a range of spaces and scenarios.

GUV↗