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At least 163 records · Page 9

Clustering and Recurring Anomaly Identification: Recurring Anomaly Detection System (ReADS)

This viewgraph presentation reviews the Recurring Anomaly Detection System (ReADS). The Recurring Anomaly Detection System is a tool to analyze text reports, such as aviation reports and maintenance records: (1) Text clustering algorithms group large quantities of reports and documents; Reduces human error and fatigue (2) Identifies interconnected reports; Automates the discovery of possible recurring anomalies; (3) Provides a visualization of the clusters and recurring anomalies We have illustrated our techniques on data from Shuttle and ISS discrepancy reports, as well as ASRS data. ReADS has been integrated with a secure online search

McIntosh, Dawn↗

What Is in Umbilicaria pustulata? A Metagenomic Approach to Reconstruct the Holo-Genome of a Lichen

Lichens are valuable models in symbiosis research and promising sources of biosynthetic genes for biotechnological applications. Most lichenized fungi grow slowly, resist aposymbiotic cultivation, and are poor candidates for experimentation. Obtaining contiguous, high-quality genomes for such symbiotic communities is technically challenging. Here, we present the first assembly of a lichen holo-genome from metagenomic whole-genome shotgun data comprising both PacBio long reads and Illumina short reads. The nuclear genomes of the two primary components of the lichen symbiosis—the fungus Umbilicaria pustulata (33 Mb) and the green alga Trebouxia sp. (53 Mb)—were assembled at contiguities comparable to single-species assemblies. The analysis of the read coverage pattern revealed a relative abundance of fungal to algal nuclei of ~20:1. Gap-free, circular sequences for all organellar genomes were obtained. The bacterial community is dominated by Acidobacteriaceae and encompasses strains closely related to bacteria isolated from other lichens. Gene set analyses showed no evidence of horizontal gene transfer from algae or bacteria into the fungal genome. Our data suggest a lineage-specific loss of a putative gibberellin-20-oxidase in the fungus, a gene fusion in the fungal mitochondrion, and a relocation of an algal chloroplast gene to the algal nucleus. Major technical obstacles during reconstruction of the holo-genome were coverage differences among individual genomes surpassing three orders of magnitude. Moreover, we show that GC-rich inverted repeats paired with nonrandom sequencing error in PacBio data can result in missing gene predictions. This likely poses a general problem for genome assemblies based on long reads.

54 ENVIRONMENTAL SCIENCES↗

NOR Flash Memory Scrubbing Application for Boot File Preservation of NASA’s Descent and Landing Computer (DLC)

Progress on NASA’s Safe and Precise Landing Integrated Capabilities Evolution (SPLICE)project continues, specifically with this development of the Descent and Landing Computer(DLC). One of the DLC’s primary contributions as a SPLICE technology is its implementationof algorithms and operation of sensors to autonomously guide a spacecraft in performing moreprecise and safer landings on celestial bodies such as the Moon and Mars. The second iterationof the DLC is known as the Engineering Test Unit (ETU) and one of its desired functionalitiesis the ability to preserve the fidelity of the system’s boot file through the use of memoryscrubbing. The ETU has two primary boards, one for housing a Multi-Processor System ona Chip (MPSoC) and the other for housing a Xilinx Kintex Ultrascale FPGA3. To emulate amemory scrubbing function implemented on the ETU’s FPGA board, the design and testingof a software application was performed on a Xilinx KCU105 FPGA evaluation board. Thememory scrubbing application had to meet certain key criteria such as (1) properly utilize withthe flash memory’s Serial Peripheral Interface (SPI) to read, write, and erase flash memoryproperly, (2) be able to detect arbitrarily large or small amounts of bit-errors, (3) be able tocorrect all detected errors, and (4) perform memory scrubbing indefinitely and autonomously.A prototype implementation was constructed and tested, demonstrating successful detectionand correction of bit errors in multiple configurations. In the form of burst errors or singularbit flips, and in amounts of errors ranging from one to fifteen (per 256 Bytes), the applicationwas successful in preserving memory fidelity.

Radiation tolerant↗

NOR Flash Memory Scrubbing Application for Boot File Preservation of NASA’s Descent and Landing Computer (DLC)

Progress on NASA’s Safe and Precise Landing Integrated Capabilities Evolution (SPLICE) project continues, specifically with this development of the Descent and Landing Computer (DLC). One of the DLC’s primary contributions as a SPLICE technology is its implementation of algorithms and operation of sensors to autonomously guide a spacecraft in performing more precise and safer landings on celestial bodies such as the Moon and Mars [1]. The second iteration of the DLC is known as the Engineering Test Unit (ETU) and one of its desired functionalities is the ability to preserve the fidelity of the system’s boot file through the use of memory scrubbing [2]. The ETU has two primary boards, one for housing a Multi-Processor System on a Chip (MPSoC) and the other for housing a Xilinx Kintex Ultrascale FPGA*. To emulate a memory scrubbing function implemented on the ETU’s FPGA board, the design and testing of a software application was performed on a Xilinx KCU105 FPGA evaluation board. The memory scrubbing application had to meet certain key criteria such as (1) properly utilize with the flash memory’s Serial Peripheral Interface (SPI) to read, write, and erase flash memory properly, (2) be able to detect arbitrarily large or small amounts of bit-errors, (3) be able to correct all detected errors, and (4) perform memory scrubbing indefinitely and autonomously. A prototype implementation was constructed and tested, demonstrating successful detection and correction of bit errors in multiple configurations. In the form of burst errors or singular bit flips, and in amounts of errors ranging from one to fifteen (per 256 Bytes), the application was successful in preserving memory fidelity.

Flash memory↗

CrossCheck: Rapid, Reproducible, and Interpretable Model Evaluation

Evaluation beyond aggregate performance metrics, e.g. F1-score, is crucial to both establish an appropriate level of trust in machine learning models and identify future model improvements. In this paper we demonstrate CrossCheck, an interactive visualization tool for rapid crossmodel comparison and reproducible error analysis. We describe the tool and discuss design and implementation details. We then present three use cases (named entity recognition, reading comprehension, and clickbait detection) that show the benefits of using the tool for model evaluation. CrossCheck allows data scientists to make informed decisions to choose between multiple models, identify when the models are correct and for which examples, investigate whether the models are making the same mistakes as humans, evaluate models’ generalizability and highlight models’ limitations, strengths and weaknesses. Furthermore, CrossCheck is implemented as a Jupyter widget, which allows rapid and convenient integration into data scientists’ model development workflows.

Arendt, Dustin L.↗

New short-time alignment technique for 70-meter antenna surface panels

With severely limited field modification time for upgrading the 64-m antenna to 70-m diameter, a new shorter time method for aligning the surface panels of the main reflector was needed. For each target on the surface panel, both distance (or range) and elevation angle measurements are made. A new technique for setting the surface panels at zenith look has been devised. This article describes the software required to convert the computed target distortions obtained from the JPL-IDEAS structural analysis computer program (defining the gravity load change from a 45-deg elevation angle to zenith look) into the theodolite reading at zenith look. The technique results in a perfectly shaped reflector at the 45-deg rigging elevation, with acceptable surface error tolerance.

Katow, M. S.↗

Engine-Monitoring Algorithm

Allowances made for erroneous sensor readings. Algorithm developed to increase reliability of digital electronic control systems for aircraft turbine engines. Detects, isolates, and accommodates failures or errors in engine sensors. Generates engine-output estimates based on measurements of inputs and outputs and detects failures of input- and output-measuring sensors.

Merrill, Walter C.↗

Optical Scanner for Linear Arrays

Optical scanner instantaneously reads contiguous lines forming scene or target in object plane. Reading active or passive and scans, continuous or discrete. Scans essentially linear with scan angle and symmetric about axial ray. Nominal focal error, resulting from curvature of scan, well within Rayleigh limit. Scanner specifically designed to be fully compatible with general requirements of linear arrays.

Finkel, M. W.↗

Implicit and Explicit Spacecraft Gyro Calibration

This paper presents a comparison between two approaches to sensor calibration. According to one approach, called explicit, an estimator compares the sensor readings to reference readings, and uses the difference between the two to estimate the calibration parameters. According to the other approach, called implicit, the sensor error is integrated to form a different entity, which is then compared with a reference quantity of this entity, and the calibration parameters are inferred from the difference. In particular this paper presents the comparison between these approaches when applied to in-flight spacecraft gyro calibration. Reference spacecraft rate is needed for gyro calibration when using the explicit approach; however, such reference rates are not readily available for in-flight calibration. Therefore the calibration parameter-estimator is expanded to include the estimation of that reference rate, which is based on attitude measurements in the form of attitude-quaternion. A comparison between the two approaches is made using simulated data. It is concluded that the performances of the two approaches are basically comparable. Sensitivity tests indicate that the explicit filter results are essentially insensitive to variations in given spacecraft dynamics model parameters.

Bar-Itzhack, Itzhack Y.↗

Technology Development for the Advanced Technology Large Aperture Space Telescope (ATLAST) as a Candidate Large UV-Optical-Infrared (LUVOIR) Surveyor

The Advanced Technology Large Aperture Space Telescope (ATLAST) team has identified five key technologies to enable candidate architectures for the future large-aperture ultraviolet/optical/infrared (LUVOIR) space observatory envisioned by the NASA Astrophysics 30-year roadmap, Enduring Quests, Daring Visions. The science goals of ATLAST address a broad range of astrophysical questions from early galaxy and star formation to the processes that contributed to the formation of life on Earth, combining general astrophysics with direct-imaging and spectroscopy of habitable exoplanets. The key technologies are: internal coronagraphs, starshades (or external occulters), ultra-stable large-aperture telescopes, detectors, and mirror coatings. Selected technology performance goals include: 1x1010 raw contrast at an inner working angle of 35 milli-arcseconds, wavefront error stability on the order of 10 pm RMS per wavefront control step, autonomous on-board sensing & control, and zero-read-noise single-photon detectors spanning the exoplanet science bandpass between 400 nm and 1.8 μm. Development of these technologies will provide significant advances over current and planned observatories in terms of sensitivity, angular resolution, stability, and high-contrast imaging. The science goals of ATLAST are presented and flowed down to top-level telescope and instrument performance requirements in the context of a reference architecture: a 10-meter-class, segmented aperture telescope operating at room temperature (~290 K) at the sun-Earth Lagrange-2 point. For each technology area, we define best estimates of required capabilities, current state-of-the-art performance, and current Technology Readiness Level (TRL) - thus identifying the current technology gap. We report on current, planned, or recommended efforts to develop each technology to TRL 5.

Technology Development↗

Design Space Exploration of Emerging Memory Technologies for Machine Learning Applications

Memory design space exploration methods study memory systems’ performances and limitations before implementation. The computer memory design space has grown exponentially because of the enormous growth of memory types, memory controllers, and application software. Computer simulators are commonly used for memory design space exploration. However, complex memory simulations take an enormous amount of time. Hence, in this paper, we proposed a machine learning-based design space exploration method for dynamic random-access memory and non-volatile memory systems. We applied our method to the CosmoGAN and LeNet applications to predict the following six memory response parameters: (i) bandwidth, (ii) power, (iii) average latency, (iv) average total latency, (v) memory reads, and (vi) memory writes. Our experimental results show that machine learning models can predict memory response parameter values faster than simulations. We used support vector machine, random forest, and gradient boosting machine learning models. We observed that the support vector machine provides better performance for bandwidth, average latency, and average total latency. The random forest model works better for memory reads and writes. The gradient boosting model provides superior prediction performance for power. We provide a detailed discussion on learning curve characteristics, error analysis, and memory type recommendation.

Hasan, S M Shamimul↗

Total-Ionizing-Dose Effects on Read Noise of MLC 3-D NAND Memories T

This paper analyzes the total ionizing dose (TID) effects on noise characteristics of commercial multi-level-cell (MLC) 3-D NAND memory technology during the read operation. Additionally, the chips were exposed to a Co-60 gamma-ray source for up to 100 krad(Si) of TID. We find that the number of noisy cells in the irradiated chip increases with TID. Bit-flip noise was more dominant for cells in an erased state during irradiation compared to programmed cells.

3-D NAND Flash↗

Formal Assurance Arguments: A Solution In Search of a Problem?

An assurance case comprises evidence and argument showing how that evidence supports assurance claims (e.g., about safety or security). It is unsurprising that some computer scientists have proposed formalizing assurance arguments: most associate formality with rigor. But while engineers can sometimes prove that source code refines a formal specification, it is not clear that formalization will improve assurance arguments or that this benefit is worth its cost. For example, formalization might reduce the benefits of argumentation by limiting the audience to people who can read formal logic. In this paper, we present (1) a systematic survey of the literature surrounding formal assurance arguments, (2) an analysis of errors that formalism can help to eliminate, (3) a discussion of existing evidence, and (4) suggestions for experimental work to definitively answer the question.

Graydon, Patrick J.↗

Error latency measurements in symbolic architectures

Error latency, the time that elapses between the occurrence of an error and its detection, has a significant effect on reliability. In computer systems, failure rates can be elevated during a burst of system activity due to increased detection of latent errors. A hybrid monitoring environment is developed to measure the error latency distribution of errors occurring in main memory. The objective of this study is to develop a methodology for gauging the dependability of individual data categories within a real-time application. The hybrid monitoring technique is novel in that it selects and categorizes a specific subset of the available blocks of memory to monitor. The precise times of reads and writes are collected, so no actual faults need be injected. Unlike previous monitoring studies that rely on a periodic sampling approach or on statistical approximation, this new approach permits continuous monitoring of referencing activity and precise measurement of error latency.

Young, L. T.↗

Generalize aerodynamic coefficient table storage, checkout and interpolation for aircraft simulation

The set of programs described has been used for rapidly introducing, checking out and very efficiently using aerodynamic tables in complex aircraft simulations on the IBM 360. The preprocessor program reads in tables with different names and dimensions and stores then on disc storage according to the specified dimensions. The tables are read in from IBM cards in a format which is convenient to reduce the data from the original graphs. During table processing, new auxiliary tables are generated which are required for table cataloging and for efficient interpolation. In addition, DIMENSION statements for the tables as well as READ statements are punched so that they may be used in other programs for readout of the data from disc without chance of programming errors. A quick data checking graphical output for all tables is provided in a separate program.

Neuman, F.↗

Impact of genotype‐calling methodologies on genome‐wide association and genomic prediction in polyploids

Abstract Discovery and analysis of genetic variants underlying agriculturally important traits are key to molecular breeding of crops. Reduced representation approaches have provided cost‐efficient genotyping using next‐generation sequencing. However, accurate genotype calling from next‐generation sequencing data is challenging, particularly in polyploid species due to their genome complexity. Recently developed Bayesian statistical methods implemented in available software packages, polyRAD, EBG, and updog, incorporate error rates and population parameters to accurately estimate allelic dosage across any ploidy. We used empirical and simulated data to evaluate the three Bayesian algorithms and demonstrated their impact on the power of genome‐wide association study (GWAS) analysis and the accuracy of genomic prediction. We further incorporated uncertainty in allelic dosage estimation by testing continuous genotype calls and comparing their performance to discrete genotypes in GWAS and genomic prediction. We tested the genotype‐calling methods using data from two autotetraploid species, Miscanthus sacchariflorus and Vaccinium corymbosum , and performed GWAS and genomic prediction. In the empirical study, the tested Bayesian genotype‐calling algorithms differed in their downstream effects on GWAS and genomic prediction, with some showing advantages over others. Through subsequent simulation studies, we observed that at low read depth, polyRAD was advantageous in its effect on GWAS power and limit of false positives. Additionally, we found that continuous genotypes increased the accuracy of genomic prediction, by reducing genotyping error, particularly at low sequencing depth. Our results indicate that by using the Bayesian algorithm implemented in polyRAD and continuous genotypes, we can accurately and cost‐efficiently implement GWAS and genomic prediction in polyploid crops.

59 BASIC BIOLOGICAL SCIENCES↗

A high-resolution single-molecule sequencing-based Arabidopsis transcriptome using novel methods of Iso-seq analysis

Accurate and comprehensive annotation of transcript sequences is essential for transcript quantification and differential gene and transcript expression analysis. Single-molecule long-read sequencing technologies provide improved integrity of transcript structures including alternative splicing, and transcription start and polyadenylation sites. However, accuracy is significantly affected by sequencing errors, mRNA degradation, or incomplete cDNA synthesis. We present a new and comprehensive Arabidopsis thaliana Reference Transcript Dataset 3 (AtRTD3). AtRTD3 contains over 169,000 transcripts—twice that of the best current Arabidopsis transcriptome and including over 1500 novel genes. Seventy-eight percent of transcripts are from Iso-seq with accurately defined splice junctions and transcription start and end sites. We develop novel methods to determine splice junctions and transcription start and end sites accurately. Mismatch profiles around splice junctions provide a powerful feature to distinguish correct splice junctions and remove false splice junctions. Stratified approaches identify high-confidence transcription start and end sites and remove fragmentary transcripts due to degradation. AtRTD3 is a major improvement over existing transcriptomes as demonstrated by analysis of an Arabidopsis cold response RNA-seq time-series. AtRTD3 provides higher resolution of transcript expression profiling and identifies cold-induced differential transcription start and polyadenylation site usage. AtRTD3 is the most comprehensive Arabidopsis transcriptome currently. It improves the precision of differential gene and transcript expression, differential alternative splicing, and transcription start/end site usage analysis from RNA-seq data. The novel methods for identifying accurate splice junctions and transcription start/end sites are widely applicable and will improve single-molecule sequencing analysis from any species.

transcription start and end sites↗

ACRRF High-Bay Dose Calculations using MCNP (Part A)

Analytical tools and models have been developed as a starting point for directly assessing dose in the Annular Core Research Reactor Facility (ACRRF) due to reactor operation. Key results include peak dose along the Central Cavity (CC) centerline (beamline) at the cavity level, dose throughout the High-Bay (HB), and dose on the facility roof for partially-shielded reactor operation where the 4” insert is removed from the CC Shield Plug (SP). Model results in the beamline are benchmarked against measured doses from passive dosimetry evaluations. Personnel total (neutron and gamma) dose in the ACRRF HB is calculated using Monte Carlo N-Particle (MCNP). Various CC and SP configurations are analyzed, including unshielded (no SP) and partially shielded (SP installed but 4” insert removed). Novel application of Variance Reduction (VR) techniques, namely the Surface Source Write (SSW) and Surface Source Read (SSR) capabilities in MCNP, enable impressive resolution (in a Monte Carlo modeling sense) of dose throughout much the facility. The VR techniques reduce stochastic error for challenging tallies, with more advanced techniques explored in the companion to this report (Part B) [1]. Supplementary studies (including a verification analysis) and pedagogic evaluations in Part B involve neutron spectra, angular distributions, and the dose impact of facility characteristics. With the SP 4” insert removed and the Lead-Boron (44”) Bucket (LB–44) in the reactor cavity, Total Effective Dose (TED) within the CC beamline is ≈140 rem per 300 MJ of reactor yield (or 3900 rem per hour at 100% Steady-State (SS) power). With no SP (unshielded) and a Free-Field (FF) cavity, TED within the beamline is ≈610 rem per 300 MJ (or 17000 rem per hour at 100% SS power). Due to the predicted collimation of radiation by the reactor pool (and partial SP, if present), beamline dose is much greater than the scattered radiation field surrounding the cavity and reactor tank. Comparisons are made to beamline dosimetry measurements to validate the model. Model predictions agree reasonably well (⪅10%) with measured quantities of neutron fluence, gamma fluence, and spectral metrics. Away from the beamline, comparisons made to previous dose measurements in the HB agreement within an order of magnitude.

61 RADIATION PROTECTION AND DOSIMETRY↗