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At least 163 records · Page 9

Measurement of the Landsat Thematic Mapper modulation transfer function using an array of point sources

This paper presents a method for measuring the Thematic Mapper (TM) imaging system point spread function (PSF) using TM imagery or a specially constructed target consisting of a two-dimensional array of approximate point sources of known dimensions and radiometric qualities. The target allows 16 separate point sources to be imaged simultaneously by the TM. The point sources were carefully placed on the ground so that their relative positions were known. Owing to sample-scene phasing, each imaged point source exhibits a different amount of blur in the digital image. The target pixels may then be recombined according to their known relative positions to form a single, sampled, nonaliased imaging system PSF. The modulation transfer function is then obtained as the modulus of the discrete Fourier transform of the PSF.

Rauchmiller, Robert F., Jr.↗

A calibration of NICMOS Camera 2 for low count rates

NICMOS 2 observations are crucial for constraining distances to most of the existing sample of z>1 SNe Ia. Unlike conventional calibration programs, these observations involve long exposure times and low count rates. Reciprocity failure is known to exist in HgCdTe devices and a correction for this effect has already been implemented for high and medium count rates. However, observations at faint count rates rely on extrapolations. Here instead, we provide a new zero-point calibration directly applicable to faint sources. This is obtained via inter-calibration of NIC2 F110W/F160W with the Wide Field Camera 3 (WFC3) in the low count-rate regime using z∼1 elliptical galaxies as tertiary calibrators. These objects have relatively simple near-IR spectral energy distributions, uniform colors, and their extended nature gives a superior signal-to-noise ratio at the same count rate than would stars. The use of extended objects also allows greater tolerances on point-spread function profiles. We find space telescope magnitude zero points (after the installation of the NICMOS cooling system, NCS) of 25.296 ±0.022 for F110W and 25.803 ±0.023 for F160W, both in agreement with the calibration extrapolated from count rates ≳1000 times larger (25.262 and 25.799). Before the installation of the NCS, we find 24.843 ±0.025 for F110W and 25.498 ±0.021 for F160W, also in agreement with the high-count-rate calibration (24.815 and 25.470). We also check the standard bandpasses of WFC3 and NICMOS 2 using a range of stars and galaxies at different colors and find mild tension for WFC3, limiting the accuracy of the zero points. To avoid human bias, our cross-calibration was “blinded” in that the fitted zero-point differences were hidden until the analysis was finalized.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Generation of brain pseudo-CTs using an undersampled, single-acquisition UTE-mDixon pulse sequence and unsupervised clustering

Purpose: MR-based pseudo-CT has an important role in MR-based radiation therapy planning and PET attenuation correction. The purpose of this study is to establish a clinically feasible approach, including image acquisition, correction, and CT formation, for pseudo-CT generation of the brain using a single-acquisition, undersampled ultrashort echo time (UTE)-mDixon pulse sequence. Methods: Nine patients were recruited for this study. For each patient, a 190-s, undersampled, single acquisition UTE-mDixon sequence of the brain was acquired (TE = 0.1, 1.5, and 2.8 ms). A novel method of retrospective trajectory correction of the free induction decay (FID) signal was performed based on point-spread functions of three external MR markers. Two-point Dixon images were reconstructed using the first and second echo data (TE = 1.5 and 2.8 ms). R2{sup ∗} images (1/T2{sup ∗}) were then estimated and were used to provide bone information. Three image features, i.e., Dixon-fat, Dixon-water, and R2{sup ∗}, were used for unsupervised clustering. Five tissue clusters, i.e., air, brain, fat, fluid, and bone, were estimated using the fuzzy c-means (FCM) algorithm. A two-step, automatic tissue-assignment approach was proposed and designed according to the prior information of the given feature space. Pseudo-CTs were generated by a voxelwise linear combination of the membership functions of the FCM. A low-dose CT was acquired for each patient and was used as the gold standard for comparison. Results: The contrast and sharpness of the FID images were improved after trajectory correction was applied. The mean of the estimated trajectory delay was 0.774 μs (max: 1.350 μs; min: 0.180 μs). The FCM-estimated centroids of different tissue types showed a distinguishable pattern for different tissues, and significant differences were found between the centroid locations of different tissue types. Pseudo-CT can provide additional skull detail and has low bias and absolute error of estimated CT numbers of voxels (−22 ± 29 HU and 130 ± 16 HU) when compared to low-dose CT. Conclusions: The MR features generated by the proposed acquisition, correction, and processing methods may provide representative clustering information and could thus be used for clinical pseudo-CT generation.

60 APPLIED LIFE SCIENCES↗

WFPC2 photometry from subtraction of TinyTim PSFs

Based upon the subtraction of TinyTim Point Spread Function (PSFs) from Principle Component Image (PC1) point-like objects, a method has been developed to determine the optimal values for the telescope jitter and the Z4 relative focus during calibration or science observations. Using these jitter and focus values, an optimal TinyTim PSF, computed over a resampled grid, is then iteratively fitted to the object, yielding an improvement in the PSF centering, more accurate photometric results and a better detection of underlying structures. Preliminary results seem to indicate that appropriate synthetic TinyTim PSFs perform as well as observed PSFs.

Remy, M.↗

A new aperture for neutron and x-ray imaging of inertial confinement fusion experiments

Recent neutron imaging of experiments at the National Ignition Facility has provided useful information about the hotspot shape and cold-fuel distribution and has also given insight into avenues for improvement. Neutron image reconstruction depends on accurate pointing information because the point-spread function of the neutron aperture is not shift invariant. Current pointing techniques are limited in their accuracy and rely upon detailed information about the as-built structure of the array, which is difficult to determine. We present a technique for extracting high-precision pointing information from both neutron and x-ray images, and a new aperture design with features to facilitate this technique, and allow future co-registration of neutron and x-ray images.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Image filtering as an alternative to the application of a different reconstruction kernel in CT imaging: Feasibility study in lung cancer screening

Purpose: While the acquisition of projection data in a computed tomography (CT) scanner is generally carried out once, the projection data is often removed from the system, making further reconstruction with a different reconstruction filter impossible. The reconstruction kernel is one of the most important parameters. To have access to all the reconstructions, either prior reconstructions with multiple kernels must be performed or the projection data must be stored. Each of these requirements would increase the burden on data archiving. This study aimed to design an effective method to achieve similar image quality using an image filtering technique in the image space, instead of a reconstruction filter in the projection space for CT imaging. The authors evaluated the clinical feasibility of the proposed method in lung cancer screening. Methods: The proposed technique is essentially the same as common image filtering, which performs processing in the spatial-frequency domain with a filter function. However, the filter function was determined based on the quantitative analysis of the point spread functions (PSFs) measured in the system. The modulation transfer functions (MTFs) were derived from the PSFs, and the ratio of the MTFs was used as the filter function. Therefore, using an image reconstructed with a kernel, an image reconstructed with a different kernel was obtained by filtering, which used the ratio of the MTFs obtained for the two kernels. The performance of the method was evaluated by using routine clinical images obtained from CT screening for lung cancer in five subjects. Results: Filtered images for all combinations of three types of reconstruction kernels (''smooth,''''standard,'' and ''sharp'' kernels) showed good agreement with original reconstructed images regarded as the gold standard. On the filtered images, abnormal shadows suspected as being lung cancers were identical to those on the reconstructed images. The standard deviations (SDs) for the difference between filtered images and reconstructed images ranged from 1.9 to 23.5 Hounsfield units for all kernel combinations; these SDs were much smaller than the noise SDs in the reconstructed images. Conclusions: The proposed method has good performance and is clinically feasible in lung cancer screening. This method can be applied to images reconstructed on any scanner by measuring the PSFs in each system.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Impact of flat panel-imager veiling glare on scatter-estimation accuracy and image quality of a commercial on-board cone-beam CT imaging system

Purpose: The purposes of this study is to measure the low frequency drop (LFD) of the modulation transfer function (MTF), associated with the long tails of the detector point spread function (PSF) of an on-board flat panel imager and study its impact on cone-beam CT (CBCT) image quality and scatter measurement accuracy. Methods: Two different experimental methods were used to characterize LFD and its associated PSF of a Varian OBI flat-panel detector system: the edge response function (ERF) method and the disk transfer function (DTF) method. PSF was estimated by fitting parametric models to these measurements for four values of the applied voltage (kVp). The resultant PSF was used to demonstrate the effect of LFD on image contrast and CT number accuracy in CBCT images reconstructed from synthetic datasets, as well as, accuracy of scatter measurements with the beam-stop method. Results: The MTFs derived from the measured ERF data revealed LFDs varying from 8% (at 60 kVp) to 10.5% (at 120 kVp), while the intensity of the long PSF tails was found to increase with increasing kVp. The veiling glare line spread functions derived from the ERF and DTF methods were in excellent agreement. Uncorrected veiling glare reduced contrast and the image intensity in CBCT reconstruction, near the phantom periphery (by 67 Hounsfield units in a 20 cm-in-diameter water phantom) and (to a smaller degree) near inhomogeneities. Use of the bow-tie filter mitigated these effects. Veiling glare also resulted in about 10%-15% overestimation of the scatter-to-primary ratio when measured with the beam-stop or beam-stop array method. Conclusions: The long tails of the detector PSF were found to have a modest dependence of beam spectrum, which is reflected on the MTF curve LFD. Our findings show that uncorrected veiling glare can affect quantitative accuracy and contrast in CBCT imaging, based on flat panel imager. In addition, it results in overestimation of the scatter-to-primary ratio, measured with the beam-stop methods.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Faint Object Camera imaging and spectroscopy of NGC 4151

We describe ultraviolet and optical imaging and spectroscopy within the central few arcseconds of the Seyfert galaxy NGC 4151, obtained with the Faint Object Camera on the Hubble Space Telescope. A narrowband image including (O III) lambda(5007) shows a bright nucleus centered on a complex biconical structure having apparent opening angle approximately 65 deg and axis at a position angle along 65 deg-245 deg; images in bands including Lyman-alpha and C IV lambda(1550) and in the optical continuum near 5500 A, show only the bright nucleus. In an off-nuclear optical long-slit spectrum we find a high and a low radial velocity component within the narrow emission lines. We identify the low-velocity component with the bright, extended, knotty structure within the cones, and the high-velocity component with more confined diffuse emission. Also present are strong continuum emission and broad Balmer emission line components, which we attribute to the extended point spread function arising from the intense nuclear emission. Adopting the geometry pointed out by Pedlar et al. (1993) to explain the observed misalignment of the radio jets and the main optical structure we model an ionizing radiation bicone, originating within a galactic disk, with apex at the active nucleus and axis centered on the extended radio jets. We confirm that through density bounding the gross spatial structure of the emission line region can be reproduced with a wide opening angle that includes the line of sight, consistent with the presence of a simple opaque torus allowing direct view of the nucleus. In particular, our modelling reproduces the observed decrease in position angle with distance from the nucleus, progressing initially from the direction of the extended radio jet, through our optical structure, and on to the extended narrow-line region. We explore the kinematics of the narrow-line low- and high-velocity components on the basis of our spectroscopy and adopted model structure.

Boksenberg, A.↗

Cassini Camera Contamination Anomaly: Experiences and Lessons Learned

We discuss the contamination 'Haze' anomaly for the Cassini Narrow Angle Camera (NAC), one of two optical telescopes that comprise the Imaging Science Subsystem (ISS). Cassini is a Saturn Orbiter with a 4-year nominal mission. The incident occurred in 2001, five months after Jupiter encounter during the Cruise phase and ironically at the resumption of planned maintenance decontamination cycles. The degraded optical performance was first identified by the Instrument Operations Team with the first ISS Saturn imaging six weeks later. A distinct haze of varying size from image to image marred the images of Saturn. A photometric star calibration of the Pleiades, 4 days after the incident, showed stars with halos. Analysis showed that while the halo's intensity was only 1 - 2% of the intensity of the central peak of a star, the halo contained 30 - 70% of its integrated flux. This condition would impact science return. In a review of our experiences, we examine the contamination control plan, discuss the analysis of the limited data available and describe the one-year campaign to remove the haze from the camera. After several long conservative heating activities and interim analysis of their results, the contamination problem as measured by the camera's point spread function was essentially back to preanomaly size and at a point where there would be more risk to continue. We stress the importance of the flexibility of operations and instrument design, the need to do early infight instrument calibration and continual monitoring of instrument performance.

Cassini↗

Spatial Resolution of a microCT Scanner

We have measured the spatial resolution of the 450 kV test-bed microCT scanner. We have also modeled the resolution analytically. The model and measurement show correspondence within 5%. Our measurement method was to use a thin tungsten wire to act as an impulse function. Therefore, the image is the impulse response, also called the point spread function (PSF) of the system. The Fourier transform (FT) of the impulse response is the modulation transfer function (MTF) of the system. We report the MTF here. By moving the wire at different positions in the scan field of view (FOV), we can measure MTF at different positions in the FOV. Since our imaging system is radially symmetric, we report MTF in two directions, radial and tangential as shown in Figure 1. The radial direction is along the line from isocenter to the wire, and the tangential is perpendicular to it.

42 ENGINEERING↗

HST observations of the gravitational lens systems HE 1104-1805 and J03.13

High angular resolution Principle Component Image (PC1) images of the gravitational lens systems HE 1104-1805 and J03.13 are presented. Using a method described in Remy et al. (1997a), optimal TinyTim Point Spread Function (PSFs) are constructed to fit at best the lensed point-like components. The derived photometry of the GL components and the detection of the lens galaxy for HE 1104-1805 are discussed. Textbook case Faint Object Spectrograph (FOS) spectra of J03.13 A and B clearly show that this double QSO is a cosmic mirage.

Remy, M.↗

PET optimization for improved assessment and accurate quantification of {sup 90}Y-microsphere biodistribution after radioembolization

Purpose: {sup 90}Y-microspheres are widely used for the radioembolization of metastatic liver cancer or hepatocellular carcinoma and there is a growing interest for imaging {sup 90}Y-microspheres with PET. The aim of this study is to evaluate the performance of a current generation PET/CT scanner for {sup 90}Y imaging and to optimize the PET protocol to improve the assessment and the quantification of {sup 90}Y-microsphere biodistribution after radioembolization. Methods: Data were acquired on a Biograph mCT-TrueV scanner with time of flight (TOF) and point spread function (PSF) modeling. Spatial resolution was measured with a{sup 90}Y point source. Sensitivity was evaluated using the NEMA 70 cm line source filled with {sup 90}Y. To evaluate the count rate performance, {sup 90}Y vials with activity ranging from 3.64 to 0.035 GBq were measured in the center of the field of view (CFOV). The energy spectrum was evaluated. Image quality with different reconstructions was studied using the Jaszczak phantom containing six hollow spheres (diameters: 31.3, 28.1, 21.8, 16.1, 13.3, and 10.5 mm), filled with a 207 kBq/ml {sup 90}Y concentration and a 5:1 sphere-to-background ratio. Acquisition time was adjusted to simulate the quality of a realistic clinical PET acquisition of a patient treated with SIR-Spheres{sup ®}. The developed methodology was applied to ten patients after SIR-Spheres{sup ®} treatment acquiring a 10 min per bed PET. Results: The energy spectrum showed the{sup 90}Y bremsstrahlung radiation. The {sup 90}Y transverse resolution, with filtered backprojection reconstruction, was 4.5 mm in the CFOV and degraded to 5.0 mm at 10 cm off-axis. {sup 90}Y absolute sensitivity was 0.40 kcps/MBq in the center of the field of view. Tendency of true and random rates as a function of the {sup 90}Y activity could be accurately described using linear and quadratic models, respectively. Phantom studies demonstrated that, due to low count statistics in {sup 90}Y PET acquisition, the optimal parameters for the standard OSEM+PSF reconstruction were only one iteration and a postreconstruction filter of 6 mm FWHM, for both TOF and non-TOF reconstructions. Moreover, when TOF is included, the signal to noise ratio increased and visibility achieved 100% by the experienced observers and 93.3% according to the Rose model of statistical detection. In 50% of patients, TOF allowed the visualization of {sup 90}Y radioembolized lesions not seen without TOF, confirming phantom results. Liver activity was accurately quantified, with no significant differences between reconstructed and actual delivered activity to the whole-liver [mean relative difference (10.2 ± 14.7)%]. Conclusions: Qualitative and quantitative{sup 90}Y PET imaging improved with the introduction of TOF in a PET/CT scanner, thereby allowing the visualization of microsphere deposition in lesions not visible in non-TOF images. This technique accurately quantifies the total activity delivered to the liver during radioembolization with {sup 90}Y-microspheres and allows dose estimation.

60 APPLIED LIFE SCIENCES↗

Slit Function Measurement of An Imaging Spectrograph Using Fourier Transform Techniques

Knowledge of a spectrograph slit function is necessary to interpret the unresolved lines in an observed spectrum. A theoretical slit function can be calculated from the sizes of the entrance slit, the detector aperture when it functions as an exit slit, the dispersion characteristic of the disperser, and the point spread function of the spectrograph. A measured slit function is preferred to the theoretical one for the correct interpretation of the spectral data. In a scanning spectrometer with a single exit slit, the slit function is easily measured. In a fixed grating/or disperser spectrograph, illuminating the entrance slit with a near monochromatic light from a pre-monochrmator or a tunable laser and varying the wavelength of the incident light can measure the slit function. Even though the latter technique had been used successfully for the slit function measurements, it had been very laborious and it would be prohibitive to an imaging spectrograph or a multi-object spectrograph that has a large field of view. We explore an alternative technique that is manageable for the measurements. In the proposed technique, the imaging spectrograph is used as a detector of a Fourier transform spectrometer. This method can be applied not only to an IR spectrograph but also has a potential to a visible/UV spectrograph including a wedge filter spectrograph. This technique will require a blackbody source of known temperature and a bolometer to characterize the interferometer part of the Fourier Transform spectrometer. This pa?er will describe the alternative slit function measurement technique using a Fourier transform spectrometer.

Park, Hongwoo↗

Luminosity functions and color-magnitude diagrams for three OB associations in the Large Magellanic Cloud

Using the point spread function photometry program DAOPHOT, we have used UBV CCD photometry to construct color-magnitude diagrams and luminosity functions for three OB associations in the Large Magellanic Cloud. The region LH 76 appears to be completely coeval; the region LH 13 shows some evidence for noncoevality which will need to be checked with spectra of the stars in question. The region LH 105, which lies on the southern edge of 30 Doradus, shows significant contamination by an underlying older population, possibly from previous star forming events. The luminosity functions, which serve as the first step toward determining the initial mass function in these regions, are calculated.

Degioia-Eastwood, K.↗

Object-space optimization of tomographic reconstructions for additive manufacturing

Volumetric 3D printing motivated by computed axial lithography enables rapid printing of homogeneous parts but requires a high dimensionality gradient-descent optimization to calculate image sets. Here we introduce a new, simpler approach to image-computation that algebraically optimizes a model of the printed object, significantly improving print accuracy of complex parts under imperfect material and optical precision by improving optical dose contrast between the target and surrounding regions. Quality metrics for volumetric printing are defined and shown to be significantly improved by the new algorithm. The approach is extended beyond binary printing to grayscale control of conversion to enable functionally graded materials. The flexibility of the technique is digitally demonstrated with realistic projector point spread functions, printing around occluding structures, printing with restricted angular range, and incorporation of materials chemistry such as inhibition. Finally, simulations show that the method facilitates new printing modalities such as printing into flat, rather than cylindrical packages to extend the applications of volumetric printing.

36 MATERIALS SCIENCE↗

A Resonant Metamaterial Line Array for Ultrasound Compressive Imaging

Abstract Acoustic metamaterials have been proposed for numerous applications including subwavelength imaging, impedance matching, and lensing. Yet, their application in compressive sensing and imaging has not been fully investigated. When metamaterials are used as resonators at certain frequencies, they can generate random radiation patterns in the transmitted waves from the transducers and received waves from a target. Compressive sensing favors such randomness inasmuch as it can increase incoherence by decreasing the amount of mutual information between any two different measurements. This study aims at assessing whether the use of resonating metamaterial unit cells in a single-layered non-optimized array between a number of ultrasound transceivers and targets can improve the sensing capacity, point-spread function of the sensing array (their beam focusing ability), and imaging performance in point-like target detection. The theoretical results are promising and can open the way for more efficient metamaterial designs with the aim of enhancing ultrasound imaging with lower number of transceivers compared to the regular systems.

Acoustics↗

Deconvolving the Nucleus of Centaurus A Using Chandra PSF Library

Centaurus A (NGC 5128) is a giant early-type galaxy containing the nearest (at 3.5 Mpc) radio-bright Active Galactic Nucleus (AGN). Cen A was observed with the High Resolution Camera (HRC) on the Chandra X-ray Observatory on several occasions since the launch in July 1999. The high-angular resolution (less than 0.5 arcsecond) Chandra/HRC images reveal X ray multi-scale structures in this object with unprecedented detail and clarity, including the bright nucleus believed to be associated with a supermassive black hole. We explored the spatial extent of the Cen A nucleus using deconvolution techniques on the full resolution Chandra images. Model point spread functions (PSFs) were derived from the standard Chandra raytrace PSF library as well as unresolved point sources observed with Chandra. The deconvolved images show that the Cen A nucleus is resolved and asymmetric. We discuss several possible causes of this extended emission and of the asymmetries.

Karovska, Margarita↗

Amplitude Metrics for Field Retrieval with Hard-Edged and Uniformly Illuminated Apertures

In field retrieval, the amplitude and phase of the generalized pupil function for an optical system are estimated from multiple defocused measurements of the system point-spread function. A baseline field reconstruction algorithm optimizing a data consistency metric is described. Additionally, two metrics specifically designed to incorporate a priori knowledge about pupil amplitude for hard-edged and uniformly illuminated aperture systems are given. Experimental results demonstrate the benefit of using these amplitude metrics in addition to the baseline metric

Thurman, Samuel T.↗