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At least 163 records · Page 9

Ion concentration ratio measurements of ion beams generated by a commercial microwave electron cyclotron resonance plasma source

A commercially available electron cyclotron resonance (ECR) plasma source (GenII Plasma Source, tectra GmbH) is widely used for surface processing. This plasma source is compatible with ultrahigh vacuum systems, and its working pressure is relatively low, around 10 –6 –10 –4 Torr even without differential pumping. Here, we report ion flux concentration ratios for each ion species in an ion beam from this source, as measured by a mass/energy analyzer that is a combination of a quadrupole mass spectrometer, an electrostatic energy analyzer, and focusing ion optics. In this study, the examined beams were those arising from plasmas produced from feed gases of H 2 , D 2 , N 2 , O 2 , Ar, and dry air over a range of input power and working pressures. H 2 (D 2 ) plasmas are widely used for nuclear fusion applications and, hence, the ion concentration ratios of H + , H 2 + , and H 3 + reported here will be useful information for research that applies this plasma source to well-controlled plasma-material interaction studies. Ion energy distributions, stability of operation, and impurity concentrations were also assessed for each of the plasma species investigated.

47 OTHER INSTRUMENTATION↗

Understanding the selectivity of nonsteroidal anti-inflammatory drugs for cyclooxygenases using quantum crystallography and electrostatic interaction energy

Quantum crystallography methods have been employed to investigate complex formation between nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase (COX) enzymes, with particular focus on the COX-1 and COX-2 isoforms. This study analyzed the electrostatic interaction energies of selected NSAIDs (flurbiprofen, ibuprofen, meloxicam and celecoxib) with the active sites of COX-1 and COX-2, revealing significant differences in binding profiles. Flurbiprofen exhibited the strongest interactions with both COX-1 and COX-2, indicating its potent binding affinity. Celecoxib and meloxicam showed a preference for COX-2, consistent with their known selectivity for this isoform, while ibuprofen showed comparable interaction energies with both isoforms, reflecting its nonselective inhibition pattern. Key amino-acid residues, including Arg120, Arg/His513 and Tyr355, were identified as critical determinants of NSAID selectivity and binding affinity. The findings highlight the complex interplay between interaction energy and selectivity, suggesting that while electrostatic interactions play a fundamental role, additional factors such as enzyme dynamics and the hydrophobic effect also contribute to the therapeutic efficacy and safety profiles of NSAIDs. These insights provide valuable guidance for the rational design of NSAIDs with enhanced therapeutic benefits and minimized adverse effects.

60 APPLIED LIFE SCIENCES↗

Science Observations of Deep Space One

During the Deep Space One (DS1) primary mission, the spacecraft will fly by asteroid 1992 KD and possibly comet Borrelly. There are two technologies being validated on DS1 that will provide science observations of these targets, the Miniature Integrated Camera Spectrometer (MICAS) and the Plasma Experiment for Planetary Exploration (PEPE). MICAS encompasses a camera, an ultraviolet imaging spectrometer and an infrared imaging spectrometer. PEPE combines an ion and electron analyzer designed to determine the three-dimensional distribution of plasma over its field of view. MICAS includes two visible wavelength imaging channels, an ultraviolet imaging spectrometer, and an infrared imaging spectrometer all of which share a single 10-cm diameter telescope. Two types of visible wavelength detectors, both operating between about 500 and 1000 nm are used: a CCD with 13-microrad pixels and an 18-microrad-per-pixel, metal-on-silicon active pixel sensor (APS). Unlike the CCD the APS includes the timing and control electronics on the chip along with the detector. The UV spectrometer spans 80 to 185 nm with 0.64-nm spectral resolution and 316-microrad pixels. The IR spectrometer covers the range from 1200 to 2400 nm with 6.6-nm resolution and 54-microrad pixels PEPE includes a very low-power, low-mass micro-calorimeter to help understand plasma-surface interactions and a plasma analyzer to identify de individual molecules and atoms in the immediate vicinity of the spacecraft that have been eroded off the surface of asteroid 1992 KD. It employs common apertures with separate electrostatic energy analyzers. It measures electron and ion energies spanning a range of 3 eV to 30 keV, with a resolution of five percent. and measures ion mass from one to 135 atomic mass units with 5 percent resolution. It electrostatically sweeps its field of view both in elevation and azimuth. Both MICAS and PEPE represent a new direction for the evolution of science instruments for interplanetary spacecraft. These two instruments incorporate a large fraction of the capability of five instruments that had typically flown on NASA's deep space missions The Deep Space One science team acknowledges the support of Philip Varghese, David H. Lehman, Leslie Livesay, and Marc Rayman for providing invaluable assistance in making the science observations possible.

Nelson, Robert M.↗

Versatile system for ion energy measurements generated by pulsed laser ionization: Insights into electron-ion dynamics

Ion energy distributions generated by pulsed laser interactions with materials are essential for applications ranging from materials science to oncology. Ion energy characterization is particularly important for an emerging mass spectrometry technique called virtual-slit cycloidal mass spectrometry (VS-CMS). The ion energy distribution influences the design and performance of VS-CMS instruments, as well as the efficacy of laser-driven ionization methods in various fields. Several established techniques, including the retarding potential method, time-of-flight (TOF) analysis, and electrostatic energy analyzers, have been employed to measure ion energy distributions. The wide range of ion energies reported highlights the strong dependence of ion energy on laser parameters, target materials, and experimental conditions, as well as the necessity of making independent measurements of the ion energy distribution for specific laser systems and materials. This paper presents the design and characterization of a simple TOF-based apparatus for measuring ion energy distributions from pulsed laser ionization without external fields. This approach minimizes perturbation of electron-ion dynamics and enables simultaneous energy measurements at multiple spatial positions. Here, the apparatus was tested using a nanosecond pulsed Nd:YAG laser operating at 1064 nm, 532 nm, and 266 nm on solid copper sheets at various laser fluences. Simultaneous measurements at different distances provide new insights into ion-electron interactions post-ionization and demonstrate the influence of laser wavelength and fluence on ion energy distributions.

Ion energy↗

Calibration and Initial Results of Space Radiation Dosimetry Using the iMESA-R

The integrated Miniaturized Electrostatic Analyzer-Reflight (iMESA-R) is a space weather instrument designed to measure plasma density, temperature, and spacecraft charging, along with total ionizing dose and dose rate. A constellation consisting of five nearly identical instruments has been designed and developed to act as science payloads hosted on-board Department of Defense satellites operating in low-Earth orbit. To validate the dosimetry component of the iMESA-R, a radiation test study was performed to calibrate the dosimeter and ascertain the attenuation due to the instrument aluminum housing. An 80 curie Cobalt-60 radioisotope source emitting beta, X-ray, and gamma ray radiation decay products was used to calibrate the dosimeter response as a function of distance and instrument shielding. We present results of the calibration study along with initial on-orbit data presented from the first operational iMESA-R hosted on-board Space Test Program Satellite 5 in a polar Earth orbit. The initial on-orbit data demonstrate the ability to map the radiation environment, particularly the South Atlantic Anomaly and the auroral regions using total ionizing dose rate due to electrons of E > 1.5 MeV and protons of E > 25 MeV.

79 ASTRONOMY AND ASTROPHYSICS↗

Optimization of laser-target parameters for the production of stable lithium beam

A laser ion source coupled with a radio frequency quadrupole linac accelerator is being proposed as a suitable system for the production of a low energy, high-current stable lithium beam. In order to maximize the lithium yield, plasmas generated by laser ablation of different materials based on lithium (Li, LiOH, and LiNbO3) have been characterized by using a Faraday cup and an electrostatic ion analyzer in the time of flight configuration. A wide range of laser power density has been investigated (109–1012 W/cm2) using two Nd:YAG lasers operating at different wavelengths (1064 nm and 532 nm), pulse durations (6 ns and 17 ns), and maximum energies (1400 mJ and 210 mJ). This paper outlines the pros and cons of the investigated materials by studying how the ion energy, yields, and charge state distributions are modified when the laser power density is changed. Considerable attention has been paid to the higher charge states of oxygen, which may occur with the same mass-to-charge ratio of Li3+. The analysis has evidenced that LiNbO3 represents a valid target since it allows minimizing the O6+/7Li3+ ratio down to 2.5% by using a laser power density of 1.8 × 1010 W/cm2. For such a condition, a Li3+ current of 1.4 mA/cm2 has been measured.

Cannavò, A. (ORCID:0000000309759630)↗

FLASH-therapy suitable single-pulse proton generation using TiH 2 under nanosecond laser irradiation

We investigated proton emission from titanium hydride (TiH 2 ) targets irradiated in vacuum by a 6-ns, 1064-nm Nd:YAG laser. Time-of-flight measurements with a Faraday cup and an electrostatic ion analyzer resolved distinct proton peaks at high pulse energies, with yields on the order of 10 9 protons per shot. Systematic scans over pulse energy and up to 1000 repeated shots showed that, while the peak amplitude gradually decreased, the integrated proton number remained nearly constant. This behavior is consistent with surface-induced broadening of the plasma expansion while bulk hydrogen is replenished by diffusion and repeated ablation of fresh TiH 2 layers. Using the measured proton numbers and pulse widths, a simple direct-plasma-injection-style scaling indicates peak currents of ∼100 mA and sub-microsecond pulse durations. The pulse structure and yield satisfy key ultra-high-dose-rate criteria and, together with sustained output over 1000 shots, support TiH 2 -based laser ion sources as practical candidates for FLASH-therapy (ultra-high-dose-rate)-oriented studies and injector development using direct plasma injection.

43 PARTICLE ACCELERATORS↗

Ultra-black coatings for space instruments: a comparison of traditional Ebonol C processes and a method for future repeatability

Ultra-black coatings have served various roles in space instrumentation and hardware. The Ebonol C coating has been used for various missions requiring low reflectivity on aluminum substrates that are electrically conducting. This coating is produced through the formation of a cupric oxide structure on an intermediate layer of copper applied to the aluminum. For many years, this commercial formulation has been used ubiquitously for space instruments. The coating relies upon details of the copper base layer that have been trade secret at various finishing companies, and the availability of the Ebonol C formulated chemistry from the chemical supplier. In recent years, this product has been discontinued at various times, leaving vendors to either rely on expired stock or to formulate their own equivalents. Here, we detail the processing methods, chemistries, and resultant coating structures that produce reflectance performance equivalent to baseline historical reflectance data. This process detail will ensure equivalent performance for such coatings for future missions and link the performance to past and currently deployed instruments.

36 MATERIALS SCIENCE↗

Ion optical design with applications to a solar wind mass spectrometer

The design of charged particle beam transport systems at lower energies is discussed. Topics discussed include: index of refraction, photometry, phase space, matrices, lenses and imaging, charged particle trajectories in crossed electric and magnetic fields, design parameters for the Wien filter, and electrostatic energy analyzer design, an annotated bibliography is presented.

Coplan, M.↗

Observations of plasmas in the Jovian magnetosphere

This paper presents an analysis of observations of large intensities of low-energy protons deep within the Jovian magnetosphere which were made by Pioneer 10 with an electrostatic plasma analyzer having an energy range from 108 eV to 4.80 keV. A proton density profile plotted against the earth-received time of the satellite signals reveals four significant plasma features: (1) a 'plasmasphere' with relatively high proton densities, located inside the flux tubes of Io at 6 Jupiter radii and extending toward the planet to at least 2.8 radii; (2) a 'plasmapause', on which Io's flux tubes are positioned; (3) a sparse sporadic zone beyond Io, extending out to 8 Jupiter radii; and (4) a ring current beginning at 8 radii, which extends outward in the form of a thin plasma disk and in which Europa is embedded. The thermal energies of the protons in each zone are determined, and it is suggested that Jupiter's ionosphere is the source of these protons. It is noted that the relationship of Io to the 'plasmapause' is probably of fundamental importance to that satellite's modulation of Jovian decametric radio emissions.

Frank, L. A.↗

The nuclear and ionic charge distribution particle experiments on the ISEE-1 and ISEE-C spacecraft

The ISEE-1 and ISEE-C instruments are designed to measure the elemental abundances, charge state composition, energy spectra, and angular distributions of energetic ions in the energy range 2 keV/charge to 80 MeV/nucleon and electrons between 75 and 1300 keV. The instrument consists of three sensor systems: (1) ULECA which is an electrostatic deflection system with rectangular solid-state detectors for the 3-560 keV/charge range; (2) ULEWATT which is a double dE/dX vs E thin-window flowthrough proportional counter/solid-state detector telescope for the 0.2-80 MeV/nucleon (Fe) range; and (3) ULEZEQ which is a combination of an electrostatic deflection analyzer and a thin-window dE/dX vs E system with thin-window proportional counter and position-sensitive solid-state detector. The applications of the instruments to solar and interplanetary phenomena and to magnetospheric acceleration and trapped particles are discussed.

Hovestadt, D.↗

Ion composition experiment

An investigation using a novel ion mass spectrometer for measuring the ionic composition of the solar wind from the ISEE-C spacecraft is described. The resolution and dynamic range of the instrument are sufficient to be able to resolve up to twelve individual ions or groups of ions. This will permit the solution of a number of fundamental problems related to solar abundances and the formation of the solar wind. The spectrometer is composed of a stigmatic Wien filter and hemispherical electrostatic energy analyzer. The use of curved electric field plates in the filter results in a substantial saving of weight with respect to a conventional filter of the same resolution and angular acceptance. The spectrometer is controlled by a microprocessor based on a special purpose computer which has three modes of operations: full and partial survey modes and a search mode. In the search mode, the instrument locks on to the solar wind. This allows four times the time resolution of the full survey mode and yields a full mass spectrum every 12.6 min.

Coplan, M. A.↗

Electron energy distributions measured during electron beam/plasma interactions

In the large vacuum facility at the NASA-Johnson Space Center an electron beam was projected 20 m parallel to B from a gun with variable accelerating potential (1.0 to 2.5 kV) to an aluminum target. The ionospheric neutral pressure and field were approximated. Beam electron energy distributions were measured directly using an electrostatic deflection analyzer and indirectly with a detector that responded to the X-rays produced by electron impact on the target. At low currents the distribution is sharply peaked at the acceleration potential. At high currents a beam plasma discharge occurs and electrons are redistributed in energy so that the former energy peak broadens to 10-15 percent FWHM with a strongly enhanced low energy tail. At the 10% of maximum point the energy spectrum ranges from less than 1/2 to 1.2 times the gun energy. The effect is qualitatively the same at all pitch angles and locations sampled.

Jost, R. J.↗

Direct observation of charge state abundances of energetic He, C, O, and Fe emitted in solar flares

The ionic charge states of helium, carbon, oxygen, and iron have been determined for three solar particle enhancements by an electrostatic deflection analyzer, which is combined with a thin window proportional counter dE/dX vs. E system. The observations are obtained during the periods September 23 to 29, 1978, June 6 to 8, 1979, and September 15 to 26, 1979, with an instrument onboard the ISEE-3 spacecraft. The mean ionic charge states for He, C, and oxygen exhibit a high degree of ionization with values of Q equals 2, 6, and 7.2, respectively. The charge state of iron is near 13 charge units. Variations from flare to flare and within the September 23, 1978 flare are small. The most surprising feature of the charge state measurement is the observation of a small (about 10%) but finite contribution of singly ionized helium.

Hovestadt, D.↗

Observations of differential charging effects on ATS 6

Differential charging effects observed in the electron data of the University of California, San Diego, auroral particles experiment on Applied Technology Satellite 6 are described and analyzed. An electrostatic barrier around the environmental measurements experiment (EME) package on ATS 6 is shown to be the natural result of dielectrics around the spacecraft which are more negatively charged than the mainframe of the spacecraft. In particular, the large dish antenna on ATS 6 causes the formation of a barrier which traps particles emitted from the EME package surface and returns them to the spacecraft. The insulating surface of the rotating University of Minnesota detector on the otherwise conducting EME package is shown to be the source of accelerated fluxes of electrons during charging events.

Olsen, R. C.↗