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At least 163 records · Page 9

Polarization of Light by Leaves and Plant Canopies

This talk will focus first on the information contained in the surface-scattered light from leaves, plant canopies and surface waters. This light is in general polarized and depends upon surface roughness. Thus, for example, - The surface reflection from shiny green leaves measured in the specular direction shows no chlorophyll absorption bands, no 'red edge.' - Conversely, the degree of linear polarization of such light displays marked variation with wavelength having local maxima in the chlorophyll absorption bands and an inverted red edge. - Plant canopies with shiny leaves distributed in angle like the area on a sphere, specularly reflect sunlight in the subsolar or specular direction- but also in every other view direction. - Canopies of green plants may appear white not green when viewed obliquely toward the sun. - In a light to moderate wind, the often blindingly bright glitter of sunlight off smooth water surfaces provides a strong, angularly narrow signature reflection characteristic of inundated vegetated areas that are big sources of atmospheric methane, a climatically important greenhouse gas. (Conversely, a blindingly bright glitter-type reflection is uncharacteristic of upland or wind ruffled open water areas that are poor sources of atmospheric methane.) Because some of these results may be 'head scratchers,' it's always important to properly calibrate ones instruments. Indeed, as the second portion of the talk will show, the characteristics of the light measuring instrument, particularly its entrance aperture, may affect the results and should be taken into account during across-instrument data comparisons.

Vanderbilt, V. C.↗

Math Description Engine Software Development Kit

The Math Description Engine Software Development Kit (MDE SDK) can be used by software developers to make computer-rendered graphs more accessible to blind and visually-impaired users. The MDE SDK generates alternative graph descriptions in two forms: textual descriptions and non-verbal sound renderings, or sonification. It also enables display of an animated trace of a graph sonification on a visual graph component, with color and line-thickness options for users having low vision or color-related impairments. A set of accessible graphical user interface widgets is provided for operation by end users and for control of accessible graph displays. Version 1.0 of the MDE SDK generates text descriptions for 2D graphs commonly seen in math and science curriculum (and practice). The mathematically rich text descriptions can also serve as a virtual math and science assistant for blind and sighted users, making graphs more accessible for everyone. The MDE SDK has a simple application programming interface (API) that makes it easy for programmers and Web-site developers to make graphs accessible with just a few lines of code. The source code is written in Java for cross-platform compatibility and to take advantage of Java s built-in support for building accessible software application interfaces. Compiled-library and NASA Open Source versions are available with API documentation and Programmer s Guide at http:/ / prim e.jsc.n asa. gov.

Shelton, Robert O.↗

SIM-Lite Update

Discussion focus on: SIM-Lite Instrument Update - 6m baseline, 50cm, approximately 900M cost; Technology Update - Systematic errors and floor; SIM-Lite terrestrial planet discovery capability; Double blind multiple planet study summary; and the changing landscape of exoplanet science and the role of SIM-Lite. Slides include technology to flight component engineering; instrumental systematic errors; ultra deep search for Earth clones; double blind test, astrometric detection of Earths in multiplanet systems; the current era of exoplanet science and where SIM-Lite fits in; the next frontier and where SIM-Lite fits in, why SIM is unique in discovering Earths; imaging planet status is uncertain without masses and ages; SIM role in establishing how planetary systems form and evolve; and SIM probes of broad planet mass range around young stars.

exoplanets↗

Comparison of Image Restoration Methods for Lunar Epithermal Neutron Emission Mapping

Orbital measurements of neutrons by the Lunar Exploring Neutron Detector (LEND) onboard the Lunar Reconnaissance Orbiter are being used to quantify the spatial distribution of near surface hydrogen (H). Inferred H concentration maps have low signal-to-noise (SN) and image restoration (IR) techniques are being studied to enhance results. A single-blind. two-phase study is described in which four teams of researchers independently developed image restoration techniques optimized for LEND data. Synthetic lunar epithermal neutron emission maps were derived from LEND simulations. These data were used as ground truth to determine the relative quantitative performance of the IR methods vs. a default denoising (smoothing) technique. We review and used factors influencing orbital remote sensing of neutrons emitted from the lunar surface to develop a database of synthetic "true" maps for performance evaluation. A prior independent training phase was implemented for each technique to assure methods were optimized before the blind trial. Method performance was determined using several regional root-mean-square error metrics specific to epithermal signals of interest. Results indicate unbiased IR methods realize only small signal gains in most of the tested metrics. This suggests other physically based modeling assumptions are required to produce appreciable signal gains in similar low SN IR applications.

McClanahan, T. P.↗

Superelastic Ball Bearings: Materials and Design to Avoid Mounting and Dismounting Brinell Damage in an Inaccessible Press-Fit Application-: Design Approach - I

Ball bearings require proper fit and installation into machinery structures (onto shafts and into bearing housings) to ensure optimal performance. For some applications, both the inner and outer race must be mounted with an interference fit and care must be taken during assembly and disassembly to avoid placing heavy static loads between the balls and races otherwise Brinell dent type damage can occur. In this paper, a highly dent resistant superelastic alloy, 60NiTi, is considered for rolling element bearing applications that encounter excessive static axial loading during assembly or disassembly. A small (R8) ball bearing is designed for an application in which access to the bearing races to apply disassembly tools is precluded. First Principles analyses show that by careful selection of materials, raceway curvature and land geometry, a bearing can be designed that allows blind assembly and disassembly without incurring raceway damage due to ball denting. Though such blind assembly applications are uncommon, the availability of bearings with unusually high static load capability may enable more such applications with additional benefits, especially for miniature bearings.

tribology↗

Acquisition and Pointing for Mars Optical Access Link

Optical characteristics can potentially benefit "access" links at Mars when transmitting data from surface to orbiting assets because of the higher gain and modulation bandwidth, compared to radio frequency (RF). Furthermore, higher bits/kg/W can be realized with low mass and power optical systems, enabling the streaming of high definition imagery. In this paper we present a conceptual design for a low complexity, autonomous optical communications link for returning data at 50-200 Mb/s from the Martian surface and for lower forward data rates of 50 kb/s to the surface. The pointing control is simplified by widening the transmitted laser beams (0.5 - 2.0 mrad) for the short distance (400-1200 Km) links. Link acquisition is based on the orbiter transceiver (OT) "blind"-pointing a laser beam to illuminate the lander transceiver (LT) on the surface. The LT acquires the link with a spectrally-filtered wide-field-of-view camera and subsequently tracks the orbiter transceiver with a two-axis, stepper-motor-actuator, to send back a laser modulated with high-rate data to the orbiting asset. The system design also has a provision for the OT transitioning from blind-pointing to closed loop tracking once it acquires the signal from the lander transceiver. Results from successful ground-based demonstrations performed at JPL, in which the pointing rate required to track an orbiter was emulated by mounting both transceivers on rotating stages, and in which we transmitted live video and pseudo-random data streams, are presented.

Optical Communication↗

Superelastic Ball Bearings: Materials and Design to Avoid Mounting and Dismounting Brinell Damage in an Inaccessible Press-fit Application-: Detailed Analysis - II

Rolling element bearings utilized in precision rotating machines require proper alignment, preload, and interference fits to ensure overall optimum performance. Hence, careful attention must be given to bearing installation and disassembly procedures to ensure the above conditions are met. Usually, machines are designed in such a way that bearings can be pressed into housings or onto shafts through the races without loading the rolling elements. However, in some instances, either due to limited size or access, a bearing must be installed or removed in such a way that the load path travels through the rolling elements. This can cause high contact stresses between the rolling elements and the races and introduces the potential for Brinell denting of the races. This paper is a companion to the Part I paper by the authors that discusses material selection and the general design philosophy for the bearing. Here, a more in-depth treatment is given to the design of a dent-resistant bearing utilizing a superelastic alloy, 60NiTi, for the races. A common bearing analysis tool based on rigid body dynamics is used in combination with finite element simulations to design the superelastic bearing. The primary design constraints are prevention of denting and avoiding the balls riding over the edge of the race groove during a blind disassembly process where the load passes through the rolling elements. Through an iterative process, the resulting bearing geometry is tailored to improve axial static load capability compared to a deep-groove ball bearing of the same size. The results suggest that careful selection of materials and bearing geometry can enable blind disassembly without damage to the raceways, which is necessary in the current application (a compressor in the International Space Station Environmental Control and Life Support System), and results in potential design flexibility for other applications, especially small machines with miniature bearings.

metals↗

Gear Tooth Wear Detection Algorithm

Vibration-based condition indicators continue to be developed for Health Usage Monitoring of rotorcraft gearboxes. Testing performed at NASA Glenn Research Center have shown correlations between specific condition indicators and specific types of gear wear. To speed up the detection and analysis of gear teeth, an image detection program based on the Viola-Jones algorithm was trained to automatically detect spiral bevel gear wear pitting. The detector was tested using a training set of gear wear pictures and a blind set of gear wear pictures. The detector accuracy for the training set was 75 percent while the accuracy for the blind set was 15 percent. Further improvements on the accuracy of the detector are required but preliminary results have shown its ability to automatically detect gear tooth wear. The trained detector would be used to quickly evaluate a set of gear or pinion pictures for pits, spalls, or abrasive wear. The results could then be used to correlate with vibration or oil debris data. In general, the program could be retrained to detect features of interest from pictures of a component taken over a period of time.

Delgado, Irebert R.↗

Determination of Ballistic Limit for IM7/8552 Using Peridynamics

Significant testing is required to design and certify primary aircraft structure subject to High Energy Dynamic Impact (HEDI) events; current work under the NASA Advanced Composites Consortium (ACC) HEDI Project seeks to determine the state-of-the-art of dynamic fracture simulations for composite structures in these events. This paper discusses one of four Progressive Damage Analysis (PDA) methods selected for this project: peridynamics, through EMU implementation. A brief discussion of peridynamic theory is provided, followed by an outline of ballistic impact testing performed for model development and assessment. Detailed modeling approach and test-analysis correlation for a single open test case are presented, followed by the results of a series of blind predictions made prior to testing and test-analysis correlation performed with measured NASA test results. Specifically, we present simulation results for the ballistic limit (V50) of IM7/8552 composite panels ballistically tested with an impactor representative of a high-velocity fan-blade-out condition. In particular, force and displacement history and the damage state determined analytically are compared to measured results. Ultimately, peridynamics has the ability to predict damage patterns, impact force and deflections during a high energy dynamic impact event on composite panels of different layups using two different types of impactors. Blind predictions were promising and increased confidence in the model for impact simulation. There are open questions regarding the fidelity of the test fixture idealization in regards to stiffness and damping which will need to be addressed in future work.

Cuenca, Fernando↗

Using Intelligent Targeting to increase the science return of a Smart Ice Storm Hunting Radar

Smart Ice Cloud Sensing (SMICES) is a small-sat concept in which a radar intelligently targets ice storms based on information collected by a lookahead radiometer. Often space observations are performed by continuously collecting data from an instrument aimed at nadir (e.g. directly below the space platform). However, if the platform has the ability to assess science utility of features being overflown, an intelligent measurement scheme can improve science return. This can be achieved by controlling the on/off state of the instrument if it is not able to continuously operate (e.g. due to energy or thermal constraints), and by allowing the instrument to view off nadir if it has pointing capabilities.In the case of SMICES, power constraints and the rarity of storms means that with blind nadir targeting SMICES would collect a limited amount of ice storm radar data. The algorithms proposed acquire measurements to maximize acquired high interest storms while concurrently collecting a background sampling of all features. We use a cloud classification system to identify five different cloud types. Six algorithms ranging from “blind” to more selective are described and results from evaluation on a dataset of 13 ground swaths covering 72,399,600 km2 of data are presented. This data is from high quality science simulations that contain all five cloud types and multiple storms. When utilizing the radiometer’s lookahead and the full range of the radar the results show a 23.7x and 1.9x increase over the base algorithm in the most and second most important cloud types respectively.

Cooke, Caitlyn↗

Evaluating Differences Among Crop Models in Simulating Soybean in-Season Growth

Crop models are useful tools for simulating agricultural systems that require continued model development and testing to increase their robustness and improve how they describe our current understanding of processes. Coordinated and “blind” evaluation of multiple models using same protocols and experimental datasets provides unique opportunities to further improve models and enhance their reliability. For soybean [Glycine max (L.) Merr.], there has been limited coordinated multi-model evaluations for the simulation of in-season plant growth dynamics. We evaluated ten dynamic soybean crop models for their simulation of in-season plant growth using data from five experiments conducted in Argentina, Brazil, France, and USA. We evaluated models after a Blind (using only phenology data) and a Full calibration (with in-season and end-of-season variables). Calibration reduced model uncertainty by reducing standard bias for the simulation of in-season variables (biomass, leaf, pod, and stem weights, and leaf area index, LAI). However, we found that most models had difficulty in reproducing leaf growth dynamics, with normalized root mean squared error (nRMSE) of 56% for leaf weight and 43% for LAI (across locations and models after Full calibration). Models with different levels of complexity and experience were capable of simulating final seed yield at maturity with reasonable accuracy (nRMSE of 8–31% after Full calibration). However, the nRMSE for pod weight (of 17–64% after Full calibration) was two-fold larger than that of seed yield. Moreover, the models differed in how they simulated timing from sowing to beginning seed growth (47–93 days) and effective seed filling period (18–54 days), owing to model structural differences in defining the reproductive developmental stages. Overall, we identified the following processes that can benefit from further model improvement: leaf expansion and senescence, reproductive phenology, and partitioning to reproductive growth. Simulation of pod wall tissue and individual seed cohorts is another aspect that many models currently lack. Model improvement can benefit from high-temporal resolution experimental datasets that concurrently account for phenology, plant growth, and partitioning. Further, we recommend collecting reproductive phenology in the field consistent with actual dry matter allocation to organs in the models and collecting multiple observations of seed and pod weight to aid model improvement for simulation of seed growth and yield formation.

Agricultural Model Intercomparison and Improvement↗

Towards a Combined Low-Earth Orbit Lightning Climatology: Current Work and Assessing South Atlantic Anomaly Influence

This presentation discusses the current status and ongoing work towards a low-Earth orbit (LEO) lightning climatological product that includes both Lightning Imaging Sensors (LIS) and the Optical Transient Detector (OTD). The project builds upon the work by Cecil et al. (2014) to include the LIS on the International Space Station (ISS), featuring additional inter-instrumental comparisons to more accurately depict the unique capabilities of each instrument. A closer examination of the interference from the South Atlantic Anomaly (SAA) was also conducted on all three LEO sensors. The SAA is a region of the magnetosphere roughly spanning the south-central Atlantic wherein the inner Van Allen radiation belts are closer to Earth than anywhere else, subjecting spacecraft in LEO to significantly higher radiation flux levels. This radiation can produce interference with the LIS and OTD instruments, manifesting as non-lightning luminous events. While these events can be identified easily enough, they can occur in such quantities that they overwhelm the sensors’ processors and effectively ‘blind’ them. This is called the First-In First-Out (FIFO) buffer overflow, and this blinded time reduced the instruments’ view-time as a result. The FIFO overflow and view-time can reliably be used to track the SAA interference (Clark et al. 2024), which allows for the lightning counts attributable to the SAA to be assessed. The impact that the SAA had on the quality of observations from the LEO lightning instrumentation and the significance for the resulting climatological products was investigated. Substantial areas of interference were identified for all three instruments using the view-time and quality flags, each with a unique shape and temporal evolution. The temporal evolution and general region affected are of particular importance when constructing a climatological product, as there are notable reductions to view-time over prolonged periods across a lightning-rich region. However, a temporal element also makes isolating the subsequent impact on the lightning signal significantly more challenging. Lightning counts in this region are highly seasonal and exhibit inter-annual variability, which is compounded by the nature of LEO observations. This study includes preliminary analysis of the impact that the SAA has on the lightning counts given the notable impact shown in the metadata.

Austin G Clark↗

The relation of motion sickness to the spatial-temporal properties of velocity storage

Tilting the head in roll to or from the upright while rotating at a constant velocity (roll while rotating, RWR) alters the position of the semicircular canals relative to the axis of rotation. This produces vertical and horizontal nystagmus, disorientation, vertigo, and nausea. With recurrent exposure, subjects habituate and can make more head movements before experiencing overpowering motion sickness. We questioned whether promethazine lessened the vertigo or delayed the habituation, whether habituation of the vertigo was related to the central vestibular time constant, i.e., to the time constant of velocity storage, and whether the severity of the motion sickness was related to deviation of the axis of eye velocity from gravity. Sixteen subjects received promethazine and placebo in a double-blind, crossover study in two consecutive 4-day test series 1 month apart, termed series I and II. Horizontal and vertical eye movements were recorded with video-oculography while subjects performed roll head movements of approx. 45 degrees over 2 s to and from the upright position while being rotated at 138 degrees /s around a vertical axis. Motion sickness was scaled from 1 (no sickness) to an endpoint of 20, at which time the subject was too sick to continue or was about to vomit. Habituation was determined by the number of head movements that subjects made before reaching the maximum motion sickness score of 20. Head movements increased steadily in each session with repeated testing, and there was no difference between the number of head movements made by the promethazine and placebo groups. Horizontal and vertical angular vestibulo-ocular reflex (aVOR) time constants declined in each test, with the declines being closely correlated to the increase in the number of head movements. The strength of vertiginous sensation was associated with the amount of deviation of the axis of eye velocity from gravity; the larger the deviation of the eye velocity axis from gravity, the more severe the motion sickness. Thus, promethazine neither reduced the nausea associated with RWR, nor retarded or hastened habituation. The inverse relationship between the aVOR time constants and number of head movements to motion sickness, and the association of the severity of motion sickness with the extent, strength, and time of deviation of eye velocity from gravity supports the postulate that the spatiotemporal properties of velocity storage, which are processed between the nodulus and uvula of the vestibulocerebellum and the vestibular nuclei, are likely to represent the source of the conflict responsible for producing motion sickness.

NASA Discipline Neuroscience↗

Effect of morphine on sympathetic nerve activity in humans

There are conflicting reports for the role of endogenous opioids on sympathetic and cardiovascular responses to exercise in humans. A number of studies have utilized naloxone (an opioid-receptor antagonist) to investigate the effect of opioids during exercise. In the present study, we examined the effect of morphine (an opioid-receptor agonist) on sympathetic and cardiovascular responses at rest and during isometric handgrip (IHG). Eleven subjects performed 2 min of IHG (30% maximum) followed by 2 min of postexercise muscle ischemia (PEMI) before and after systemic infusion of morphine (0.075 mg/kg loading dose + 1 mg/h maintenance) or placebo (saline) in double-blinded experiments on separate days. Morphine increased resting muscle sympathetic nerve activity (MSNA; 17 +/- 2 to 22 +/- 2 bursts/min; P < 0.01) and increased mean arterial pressure (MAP; 87 +/- 2 to 91 +/- 2 mmHg; P < 0.02), but it decreased heart rate (HR; 61 +/- 4 to 59 +/- 3; P < 0.01). However, IHG elicited similar increases for MSNA, MAP, and HR between the control and morphine trial (drug x exercise interaction = not significant). Moreover, responses to PEMI were not different. Placebo had no effect on resting, IHG, and PEMI responses. We conclude that morphine modulates cardiovascular and sympathetic responses at rest but not during isometric exercise.

Non-NASA Center↗

Selective norepinephrine reuptake inhibition as a human model of orthostatic intolerance

BACKGROUND: Observations in patients with functional mutations of the norepinephrine transporter (NET) gene suggest that impaired norepinephrine uptake may contribute to idiopathic orthostatic intolerance. METHODS AND RESULTS: We studied the effect of the selective NET blocker reboxetine and placebo in a randomized, double-blind, crossover fashion on cardiovascular responses to cold pressor testing, handgrip testing, and a graded head-up tilt test (HUT) in 18 healthy subjects. In a subset, we determined isoproterenol and phenylephrine sensitivities. Subjects ingested 8 mg reboxetine or placebo 12 hours and 1 hour before testing. In the supine position, heart rate was 65+/-2 bpm with placebo and 71+/-3 bpm with reboxetine. At 75 degrees HUT, heart rate was 84+/-3 and 119+/-4 bpm with placebo and with reboxetine (P<0.0001). Mean arterial pressure was 85+/-2 with placebo and 91+/-2 mm Hg with reboxetine while supine (P<0.01) and 88+/-2 mm Hg and 90+/-3 mm Hg at 75 degrees HUT. Blood pressure responses to cold pressor and handgrip testing were attenuated with reboxetine. Reboxetine increased the sensitivity to the chronotropic effect of isoproterenol and the pressor effect of phenylephrine. Vasovagal reactions occurred in 9 subjects on placebo and in 1 subject on reboxetine. CONCLUSIONS: Selective NET blockade creates a phenotype that resembles idiopathic orthostatic intolerance. This observation supports the hypothesis that disordered norepinephrine uptake mechanisms can contribute to human cardiovascular disease. Our study also suggests that NET inhibition might be useful in preventing vasovagal reactions.

Non-NASA Center↗

Pyruvate ingestion for 7 days does not improve aerobic performance in well-trained individuals

The purposes of the present studies were to test the hypotheses that lower dosages of oral pyruvate ingestion would increase blood pyruvate concentration and that the ingestion of a commonly recommended dosage of pyruvate (7 g) for 7 days would enhance performance during intense aerobic exercise in well-trained individuals. Nine recreationally active subjects (8 women, 1 man) consumed 7, 15, and 25 g of pyruvate and were monitored for a 4-h period to determine whether blood metabolites were altered. Pyruvate consumption failed to significantly elevate blood pyruvate, and it had no effect on indexes of carbohydrate (blood glucose, lactate) or lipid metabolism (blood glycerol, plasma free fatty acids). As a follow-up, we administered 7 g/day of either placebo or pyruvate, for a 1-wk period to seven, well-trained male cyclists (maximal oxygen consumption, 62.3 +/- 3.0 ml. kg(-1). min(-1)) in a randomized, double-blind, crossover trial. Subjects cycled at 74-80% of their maximal oxygen consumption until exhaustion. There was no difference in performance times between the two trials (placebo, 91 +/- 9 min; pyruvate, 88 +/- 8 min). Measured blood parameters (insulin, peptide C, glucose, lactate, glycerol, free fatty acids) were also unaffected. Our results indicate that oral pyruvate supplementation does not increase blood pyruvate content and does not enhance performance during intense exercise in well-trained cyclists.

Randomized Controlled Trial↗

Acute effect of ephedrine on 24-h energy balance

Ephedrine is used to help achieve weight control. Data on its true efficacy and mechanisms in altering energy balance in human subjects are limited. We aimed to determine the acute effect of ephedrine on 24-h energy expenditure, mechanical work and urinary catecholamines in a double-blind, randomized, placebo-controlled, two-period crossover study. Ten healthy volunteers were given ephedrine (50 mg) or placebo thrice daily during each of two 24-h periods (ephedrine and placebo) in a whole-room indirect calorimeter, which accurately measures minute-by-minute energy expenditure and mechanical work. Measurements were taken of 24-h energy expenditure, mechanical work, urinary catecholamines and binding of (+/-)ephedrine in vitro to human beta1-, beta2- and beta3-adrenoreceptors. Twenty-four-hour energy expenditure was 3.6% greater (8965+/-1301 versus 8648+/-1347 kJ, P<0.05) with ephedrine than with placebo, but mechanical work was not different between the ephedrine and placebo periods. Noradrenaline excretion was lower with ephedrine (0.032+/-0.011 microg/mg creatinine) compared with placebo (0.044+/-0.012 microg/mg creatinine) (P<0.05). (+/-)Ephedrine is a relatively weak partial agonist of human beta1- and beta2-adrenoreceptors, and had no detectable activity at human beta3-adrenoreceptors. Ephedrine (50 mg thrice daily) modestly increases energy expenditure in normal human subjects. A lack of binding of ephedrine to beta3-adrenoreceptors and the observed decrease in urinary noradrenaline during ephedrine treatment suggest that the thermogenic effect of ephedrine results from direct beta1-/beta2-adrenoreceptor agonism. An indirect beta3-adrenergic effect through the release of noradrenaline seems unlikely as urinary noradrenaline decreased significantly with ephedrine.

Non-NASA Center↗

Three-dimensional echocardiographic planimetry of maximal regurgitant orifice area in myxomatous mitral regurgitation: intraoperative comparison with proximal flow convergence

OBJECTIVES: We sought to validate direct planimetry of mitral regurgitant orifice area from three-dimensional echocardiographic reconstructions. BACKGROUND: Regurgitant orifice area (ROA) is an important measure of the severity of mitral regurgitation (MR) that up to now has been calculated from hemodynamic data rather than measured directly. We hypothesized that improved spatial resolution of the mitral valve (MV) with three-dimensional (3D) echo might allow accurate planimetry of ROA. METHODS: We reconstructed the MV using 3D echo with 3 degrees rotational acquisitions (TomTec) using a transesophageal (TEE) multiplane probe in 15 patients undergoing MV repair (age 59 +/- 11 years). One observer reconstructed the prolapsing mitral leaflet in a left atrial plane parallel to the ROA and planimetered the two-dimensional (2D) projection of the maximal ROA. A second observer, blinded to the results of the first, calculated maximal ROA using the proximal convergence method defined as maximal flow rate (2pi(r2)va, where r is the radius of a color alias contour with velocity va) divided by regurgitant peak velocity (obtained by continuous wave [CW] Doppler) and corrected as necessary for proximal flow constraint. RESULTS: Maximal ROA was 0.79 +/- 0.39 (mean +/- SD) cm2 by 3D and 0.86 +/- 0.42 cm2 by proximal convergence (p = NS). Maximal ROA by 3D echo (y) was highly correlated with the corresponding flow measurement (x) (y = 0.87x + 0.03, r = 0.95, p < 0.001) with close agreement seen (AROA (y - x) = 0.07 +/- 0.12 cm2). CONCLUSIONS: 3D echo imaging of the MV allows direct visualization and planimetry of the ROA in patients with severe MR with good agreement to flow-based proximal convergence measurements.

NASA Discipline Cardiopulmonary↗