Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “biological physics”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 163 records · Page 9
All sourcesNASA NTRSDOE OSTI
NASA NTRS2018

The Importance of Contamination Knowledge - Insights into Mars Sample Return

The Astromaterials Acquisition and Curation Office at NASA Johnson Space Center (JSC), in Houston, TX (henceforth Curation Office) manages the curation of all past, present, and future extraterrestrial samples returned by NASA missions and shared collections from international partners, preserving their integrity for future scientific study while providing the samples to the international community in a fair and unbiased way. The Curation Office also curates all reference and witness materials for each mission (e.g., flight and non-flight hardware coupons; lubricants; non-flight, flight-like, and flown witness plates). These reference and witness materials provide the scientific community with the fundamental ability to reconstruct the contamination/alteration history of the sample collection through the course of the mission, with the overall goal of strengthening the scientific conclusions drawn from the study of returned materials. The information gained from characterizing the physical, biological, inorganic, and organic chemical properties of reference and witness materials is defined as the Contamination Knowledge (CK) of the sample collection. Unlike the data collected for Contamination Control (CC) and Planetary Protection (PP), CK is exclusively concerned with preserving reference and witness materials for study by future scientists upon sample return. Although CC and PP data collected for sample integrity and forward contamination purposes can be complementary to CK, they are two separate data sets with distinct objectives. A robust collection of samples for CK is necessary to allow the extraterrestrial material in a returned sample to be distinguished from terrestrial contamination. Traditionally CK is utilized by sample scientists in order to accomplish the mission’s scientific objectives, however this information can also be utilized by the Office of Planetary Protection to help evaluate the presence of any back contamination. Mars 2020, the first phase of a potential multipart Mars Sample Return (MSR) campaign, is expected to contribute to NASA’s Mars Exploration Program Science Goals by filling in knowledge gaps concerning: 1) the existence of past or present life on Mars, 2) the past and present climate of Mars, 3) the geology of Mars, and 4) hazards associated with human exploration of Mars. Although there is debate concerning which samples will best answer these questions, the necessity for proper sample blanks is well-understood. The CC and PP requirements, driven by the restricted Class V mission designation, are the most stringent of any sample return mission in recent history. The extremely low levels of allowable terrestrial contamination on the spacecraft and rover can complicate these analyses given the detection limits of current analytical instrumentation, especially in the case of biological contamination. By collecting and curating unanalyzed samples specifically for CK, future sample scientists will not be relegated to: 1) relying on data collected using possibly obsolete tools and techniques for return sample blanks, or 2) using remnants of extracted and/or cultured samples from ATLO (Assembly, Test, and Launch Operations), which could be incompatible with the desired experimental endpoints or state-of-the-art techniques available at the time of sample return.The addition of biological experimental endpoints to a sample return campaign’s objectives broadens the requisite range in preservation environments (e.g. inert ultra-pure nitrogen gaseous environment at 18 degrees Centigrade versus less than or equal to minus 80 degrees Centigrade) and types of CK samples. As a result, the Curation Office will also curate the following CK samples at less than or equal to minus 80 degrees Centigrade for the Mars 2020 mission: 1) unanalyzed swabs and wipes in sterile containers, 2) all recirculation filters from the clean rooms used for sample and caching subsystem assembly and all filters from the laminar flow benches used to assemble sample intimate hardware, and 3) witness plates collecting airborne contamination within the assembly clean rooms. It has been Curation Office policy since the Apollo missions to preserve as many pristine samples as possible for future scientific research. Although CK is required to be collected for all stages of the MSR campaign, the CK for the Mars 2020 mission is the most critical for understanding contamination in the returned samples given the intimacy between the Martian samples and the Mars 2020 flight hardware. This presentation highlights the importance of CK for sample return missions as well as the traditional and novel types of CK samples required for a successful MSR campaign.

Harrington, A. D.↗
NASA NTRS2019

Providing a Service that Doubles the ISS Science Data Return

NASA’s missions rely on the Space Network to relay critical mission data to control centers and scientists here on Earth. The international Space Station is NASA’s most critical missions that relies on this network. The International Space Station plays a key role in the international science community, enabling human spaceflight, space and Earth science experiments, as well as technology demonstrations, in the space environment. The unique environment of the station’s approximately 250-mile-high orbit allows astronauts to conduct experiments which provide valuable insight in the fields of physics, biology, astronomy, meteorology and more. The station also transmits time-sensitive, mission-critical data like information about the crew’s health and the status of the station’s systems.

Barclay, Catherine B.↗
NASA NTRS2020

Guidelines for Assessing the Toxic Hazard of Spacecraft Chemicals and Test Materials

This document describes the criteria and procedural guidelines used by the NASA/JSC Toxicology Office (JSCSTO), to perform toxicological evaluations. The JSCSTO is responsible for conducting toxicological assessments and assigning toxic hazard levels (THLs) for essentially all chemicals and test materials to be used in or transported to the habitable areas of U.S. spacecraft, non‐U.S. spacecraft inhabitaed by U.S. crew members or habitable areas of off‐Earth habitats where U.S. crew members would be present, including chemicals carried by visiting spacecraft(visiting vehicles) to and from the International Space Station (ISS). Biohazard assessments for biological materials used in payload experiments are performed by the NASA Biosafety Review Board. Radioactive materials are assessed by the Space Radiation Analysis Group for radiation hazards; the flammability rating on flammable materials is assessed by the JSC Materials and Processes Branch, ES4. This document will focus on the assessment of chemically‐induced toxicity hazards. The toxicological assessments, together with assessments on radioactive, biological, physical, and flammability hazards, are incorporated into a mission‐specific Hazardous Materials Summary Table (HMST).

Valerie Elizabeth Ryder↗
NASA NTRSDate not supplied

Experimental and CFD Investigation of the Titled Jet Behavior in the Zero Boil-Off Tank (ZBOT) Experiment

Screens are used in cryogenic storage tanks to diffuse the incoming gas or liquid injection/flow into the tank. Meshed screens were also used in the jet mixing pressure control tests of the Zero Boil-Off Tank (ZBOT) Experiment which was recently performed aboard the International Space Station (ISS). The ZBOT pressure control studies used a liquid jet that was intended to be aligned with the longitudinal axis of the tank. A cartridge consisting of a honeycomb flow straightener and two screen diffusers, one upstream of the honeycomb, and one downstream, were designed to obtain the desired velocity profile in a manner that would be consistent in all the tests and could also be used as an input to the CFD simulations. Unfortunately, during the flight operations, the Digital Particle Image Velocimetry (DPIV) measurements indicated that the jet actually exited the nozzle at an angle to the main axis. This unexpected tilt affected the motion and deformation of the ullage during the pressure control tests, influencing the initial pressure drops. Upon disassembling the experiment hardware, it was discovered that the screen diffuser upstream of the honeycomb was clogged with debris. Since this behavior is important, not only to the follow-on ZBOT-NC experiment, but also to the operation of cryogenics storage tanks in general, a series of ground-based experiments and parametric CFD model simulations were performed to understand and characterize the tilted flow in terms of the clogged area of the upstream screen and the jet velocity. The experimental and CFD results surprisingly and non-intuitively showed that although the modification of the flow originated from the clogging of the upstream screen, the presence of the downstream unclogged screen was also necessary to produce the tilted jet. Two different CFD models were used for the numerical simulations, and only the one using a porous media formulation to capture the screen pressure drop was able to produce the correct tilting behavior. Parametric runs with the porous media CFD model were used to characterize the jet tilt in terms of the blockage area and jet velocity for both the future ZBOT-NC Experiment and other propellant tank applications. Supported by NASA Biological & Physical Sciences (BPS) Division, Physical Sciences Research Program, NASA HQ, USA.

Cryogenic Fluid Management↗
NASA NTRSDate not supplied

Active and Passive Storage Solutions for Low Temperature Lunar Sample Return

Active and passive thermal storage solutions to return lunar biological, physical science and/or geology samples to the Earth are under development. Temperature requirements for biological/physical science sample conditioning range from -100˚C to -153˚C and possibly down to -253˚C for geological samples. The lower limit for geological samples is derived from the temperature of permanently shadowed regions on the lunar surface and the sublimation temperature of specific volatiles of interest (i.e., H2O, NH3 and CH4). Individual samples for the lunar application are expected to be less than 50 kg with a 700 kg allowance for the container and refrigeration. Requiring no electrical power or heat rejection, passive approaches, comprised of high performance insulation and consumable Joule-Thompson cooling, may be preferred for shorter duration missions (< 30 days) to provide significant mass savings. Active storage approaches with cryogenic cooling may be necessary to preserve samples for longer periods of time. A notional passive storage concept with an internal vapor cooled shield is shown below. The vapor cooled shield contains the sample and is isolated from the outer container with concentric reflective rigid shields and conventional multi-layer and/or aerogel insulation on the outer layer. A special removable, insulating end cap to stow or retrieve the sample is included.

Lunar Sample Return↗
DOE OSTI2024

Physical insights into biological memory using phospholipid membranes

Electrical signals may propagate along neuronal membranes in the brain, thus enabling communication between nerve cells. In doing so, lipid bilayers, fundamental scaffolds of all cell membranes, deform and restructure in response to such electrical activity. These changes impact the electromechanical properties of the membrane, which then physically store biological memory. This memory can exist either over a short or long period of time. Traditionally, biological memory is defined by the strengthening or weakening of transmissions between individual neurons. In this report we show that electrical stimulation may also alter the properties of the lipid membrane, thus pointing toward a novel mechanism for memory storage. Furthermore, based on the analysis of existing electrophysiological data, we study molecular mechanisms underlying the long-term potentiation in phospholipid membranes. Finally, we examine possible relationships between the memory capacitive properties of lipid membranes, neuronal learning, and memory.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2022

Effects of physical, chemical, and biological ageing on the mineralization of pine wood biochar by a Streptomyces isolate

If biochar is to be used for carbon (C) management, we must understand how weathering or ageing affects biochar C mineralization. Here, we incubated aged and unaged eastern white pine wood biochar produced at 350 and 550°C with a Streptomyces isolate, a putative biochar-decomposing microbe. Ageing was accelerated via three different processes, namely, (a) physical ageing–subjecting biochar to alternating freeze-thaw and wet-dry cycles, (b) chemical ageing–treating biochar with concentrated hydrogen peroxide and (c) biological ageing–incubating biochar in the presence of nutrients and microorganisms. Elemental composition and surface chemistry (Fourier Transform Infrared spectroscopy) of biochar samples were compared before and after ageing. Biochar C mineralization between ageing treatments was significantly different in the case of 350°C biochar ( p value = 0.03). Among the 350°C biochars, physical ageing resulted in the greatest increase (by 103%) in biochar C mineralization ( p value = 0.05). However, in the case of 550°C biochar, ageing did not result in a significant change in biochar C mineralization ( p value = 0.40). Biochar C mineralization was positively correlated with an increase in O/C ratio post-ageing ( r s = 0.86, p value = 0.01). In the case of 350°C biochar, surface oxidation during ageing enhanced biochar degradation by the isolate. For 550°C biochar, however, ageing did not significantly increase biochar C mineralization, likely due to high condensed aromatic C content and lower surface oxidation during ageing. The results from our study suggest that low temperature aged biochar is more susceptible to biological degradation by soil microbes. These findings have implications for the use of biochar for long term C storage in soils.

54 ENVIRONMENTAL SCIENCES↗
NASA NTRS1999

Physical Control of Biological Productivity Off the Coast of Peru During the 1997-1998 El Nino

Satellite observations and an ecosystem model are used to understand the variability in the planktonic ecosystem off Peru for the period January 1996 to May 1998. The objective of this study is to quantify the changes in the ecosystem components, carbon pathways, and available food for small pelagic fish that occur associated with the change in physical forcing due to El Nino. Two periods are distinguished based on the observed sea level anomaly: a La Nina (LaN) period (1996) in which sea level was below normal and El Nino (EN), the average conditions for December 1997, in which the sea level was anomalously high. There are three phytoplankton size classes (pico-, nano-, and net-phytoplankton) which compete for nutrients and are eaten by three zooplankton size classes. The ecosystem model is forced by alongshore wind speed measured by the NASA Scatterometer (NSCAT) and the European Remote-sensing Satellites (ERS-1 and ERS-2). Larger, slower growing organisms are more sensitive to physical disturbance than smaller organisms (Carr, 1998]. In the present simulation as well, the primary effect of the El Nino (reduced nutrient supply, and increased temperature) is to reduce the biomass of large cells (netphytoplankton) and consequently of the zooplankton that rely on large cells as food source. EN conditions are accompanied by a rearrangement of carbon pathways: comparable uptake goes into reduced biomass accumulation, increased losses to respiration, reduced carbon export, and much reduced carbon available to fish. The star indicates the remotely sensed biomass (assuming a constant carbon to chlorophyll ratio of 60) as measured by the Ocean Color and Temperature Sensor (Nov.-Dec. 1996) and the Sea-viewing Wide Field-of-view Sensor (Dec. 1997). The model, which assumes no light limitation, overestimates total phytoplankton biomass. Additional Information is contained in the original.

Carr, Mary-Elena↗
DOE OSTI2024

Evolution of oxygen and stratification and their relationship in the North Pacific Ocean in CMIP6 Earth system models

Abstract. This study examines the linkages between the upper-ocean (0–200 m) oxygen (O2) content and stratification in the North Pacific Ocean using four Earth system models (ESMs), an ocean hindcast simulation, and an ocean reanalysis. The trends and variability in oceanic O2 content are driven by the imbalance between physical supply and biological demand. Physical supply is primarily controlled by ocean ventilation, which is responsible for the transport of O2-rich surface waters to the subsurface. Isopycnic potential vorticity (IPV), a quasi-conservative tracer proportional to density stratification that can be evaluated from temperature and salinity measurements, is used herein as a dynamical proxy for ocean ventilation. The predictability potential of the IPV field is evaluated through its information entropy. The results highlight a strong O2–IPV connection and somewhat higher (as compared to the rest of the basin) predictability potential for IPV across the tropical Pacific, where the El Niño–Southern Oscillation occurs. This pattern of higher predictability and strong anticorrelation between O2 and stratification is robust across multiple models and datasets. In contrast, IPV at mid-latitudes has low predictability potential and its center of action differs from that of O2. In addition, the locations of extreme events or hotspots may or may not differ between the two fields, with a strong model dependency, which persists in future projections. On the one hand, these results suggest that it may be possible to monitor ocean O2 in the tropical Pacific based on a few observational sites co-located with the more abundant IPV measurements; on the other, they lead us to question the robustness of the IPV–O2 relationship in the extratropics. The proposed framework helps to characterize and interpret O2 variability in relation to physical variability and may be especially useful in the analysis of new observation-based data products derived from the BGC-Argo float array in combination with the traditional but far more abundant Argo data.

Novi, Lyuba↗
NASA NTRS1973

Water quality parameters of harbors of Charlotte Amalie, St. Thomas, Virgin Islands: Acquisition of in situ water data, intercorrelation of selected water parameters, and initial correlation of these in situ biological, chemical and physical data with ERTS-1 bulk CCT MSS band 5 data

The author has identified the following significant results. Remote sensing by the ERTS-1 satellite was compared with selected water quality parameters including pH, salinity, conductivity, dissolved oxygen, water depth, water temperature, turbidity, plankton concentration, current variables, chlorophylla, total carotenoids, and species diversity of the benthic community. Strong correlation between turbidity and MSS-sensed radiance was recorded and less strong correlations between the two plankton pigments and radiance. Turbidity and benthic species diversity were highly correlated furnishing an inferential tie between an easily sensed water quality variable and a sensitive indicator of average water quality conditions.

Coulbourn, W. C.↗
NASA NTRS1983

Global Change: A Biogeochemical Perspective

A research program that is designed to enhance our understanding of the Earth as the support system for life is described. The program change, both natural and anthropogenic, that might affect the habitability of the planet on a time scale roughly equal to that of a human life is studied. On this time scale the atmosphere, biosphere, and upper ocean are treated as a single coupled system. The need for understanding the processes affecting the distribution of essential nutrients--carbon, nitrogen, phosphorous, sulfur, and water--within this coupled system is examined. The importance of subtle interactions among chemical, biological, and physical effects is emphasized. The specific objectives are to define the present state of the planetary life-support system; to ellucidate the underlying physical, chemical, and biological controls; and to provide the body of knowledge required to assess changes that might impact the future habitability of the Earth.

Mcelroy, M.↗
NASA NTRS2010

The Era of International Space Station Utilization Begins: Research Strategy, International Collaboration, and Realized Potential

With the assembly of the International Space Station (ISS) nearing completion and the support of a full-time crew of six, a new era of utilization for research is beginning. For more than 15 years, the ISS international partnership has weathered financial, technical and political challenges proving that nations can work together to complete assembly of the largest space vehicle in history. And while the ISS partners can be proud of having completed one of the most ambitious engineering projects ever conceived, the challenge of successfully using the platform remains. During the ISS assembly phase, the potential benefits of space-based research and development were demonstrated; including the advancement of scientific knowledge based on experiments conducted in space, development and testing of new technologies, and derivation of Earth applications from new understanding. The configurability and human-tended capabilities of the ISS provide a unique platform. The international utilization strategy is based on research ranging from physical sciences, biology, medicine, psychology, to Earth observation, human exploration preparation and technology demonstration. The ability to complete follow-on investigations in a period of months allows researchers to make rapid advances based on new knowledge gained from ISS activities. During the utilization phase, the ISS partners are working together to track the objectives, accomplishments, and the applications of the new knowledge gained. This presentation will summarize the consolidated international results of these tracking activities and approaches. Areas of current research on ISS with strong international cooperation will be highlighted including cardiovascular studies, cell and plant biology studies, radiation, physics of matter, and advanced alloys. Scientific knowledge and new technologies derived from research on the ISS will be realized through improving quality of life on Earth and future spaceflight endeavours. Extension of the ISS through 2020 and beyond will insure that the benefits of research will be achievable for the International Partnership.

Thumm, Tracy↗
NASA NTRSDate not supplied

The Light Microscopy Module A Facility Overview-History and Science

We will share a brief history and provide a science overview of the many accomplishments of the Light Microscopy Module (LMM), a microscope that has been operating in the microgravity environment of the International Space Station (ISS) since 2010. It will be removed in October 2021. It was initially outfitted for the Constrained Vapor Bubble – Wickless Heat Pipe experiment. It was later reconfigured and upgraded many times to support a broad portfolio of Physical science and Biological experiments including: Complex Fluids, Colloids, Macro-Molecular Biophysics, Protein Crystals, and Plant Biology. The LMM has enabled many significant studies and discoveries and has seen its fair share of pleasant surprises. These include recording order arising out of disorder, e.g., systems of colloids that were glasses on Earth crystallizing to form large defect-free crystals, nematic ordering of elliptical colloids, and colloidal-polymer systems crystallizing. The LMM science teams have also seen how to improve product stabilizers once the effects of sedimentation on Earth were removed; they were able to see which tagged genes express in plants when gravity is removed, telling them which genes are essential for growing plants in space; they’ve tested protein crystal growth models; checked models for creating bijel electrodes that turn batteries into fast-charging supercapacitors; tested many forms of colloidal self-assembly: including those using depletion attraction, magnetic fields, and critical Casimir forces; they’ve observed explosive bubble nucleation in a wickless heat pipe, and much more. This work has been supported by the NASA Biological and Physical Sciences (BPS) Division and the ISS Program Office, Johnson Space Center Code OZ and Code OB, the Center for the Advancement of Science in Space (CASIS) / ISS National Lab, EPSCoR, and ISS international partners from ESA – the Netherlands and Italy, CSA, JAXA and S. Korea, and by Space Act Agreements with Procter and Gamble (P&G).

Colloids↗
NASA NTRS2013

Galactic Cosmic Ray Event-Based Risk Model (GERM) Code

This software describes the transport and energy deposition of the passage of galactic cosmic rays in astronaut tissues during space travel, or heavy ion beams in patients in cancer therapy. Space radiation risk is a probability distribution, and time-dependent biological events must be accounted for physical description of space radiation transport in tissues and cells. A stochastic model can calculate the probability density directly without unverified assumptions about shape of probability density function. The prior art of transport codes calculates the average flux and dose of particles behind spacecraft and tissue shielding. Because of the signaling times for activation and relaxation in the cell and tissue, transport code must describe temporal and microspatial density of functions to correlate DNA and oxidative damage with non-targeted effects of signals, bystander, etc. These are absolutely ignored or impossible in the prior art. The GERM code provides scientists data interpretation of experiments; modeling of beam line, shielding of target samples, and sample holders; and estimation of basic physical and biological outputs of their experiments. For mono-energetic ion beams, basic physical and biological properties are calculated for a selected ion type, such as kinetic energy, mass, charge number, absorbed dose, or fluence. Evaluated quantities are linear energy transfer (LET), range (R), absorption and fragmentation cross-sections, and the probability of nuclear interactions after 1 or 5 cm of water equivalent material. In addition, a set of biophysical properties is evaluated, such as the Poisson distribution for a specified cellular area, cell survival curves, and DNA damage yields per cell. Also, the GERM code calculates the radiation transport of the beam line for either a fixed number of user-specified depths or at multiple positions along the Bragg curve of the particle in a selected material. The GERM code makes the numerical estimates of basic physical and biophysical quantities of high-energy protons and heavy ions that have been studied at the NASA Space Radiation Laboratory (NSRL) for the purpose of simulating space radiation biological effects. In the first option, properties of monoenergetic beams are treated. In the second option, the transport of beams in different materials is treated. Similar biophysical properties as in the first option are evaluated for the primary ion and its secondary particles. Additional properties related to the nuclear fragmentation of the beam are evaluated. The GERM code is a computationally efficient Monte-Carlo heavy-ion-beam model. It includes accurate models of LET, range, residual energy, and straggling, and the quantum multiple scattering fragmentation (QMSGRG) nuclear database.

Cucinotta, Francis A.↗
NASA NTRS1986

Physics through the 1990s: Scientific interfaces and technological applications

The volume examines the scientific interfaces and technological applications of physics. Twelve areas are dealt with: biological physics-biophysics, the brain, and theoretical biology; the physics-chemistry interface-instrumentation, surfaces, neutron and synchrotron radiation, polymers, organic electronic materials; materials science; geophysics-tectonics, the atmosphere and oceans, planets, drilling and seismic exploration, and remote sensing; computational physics-complex systems and applications in basic research; mathematics-field theory and chaos; microelectronics-integrated circuits, miniaturization, future trends; optical information technologies-fiber optics and photonics; instrumentation; physics applications to energy needs and the environment; national security-devices, weapons, and arms control; medical physics-radiology, ultrasonics, MNR, and photonics. An executive summary and many chapters contain recommendations regarding funding, education, industry participation, small-group university research and large facility programs, government agency programs, and computer database needs.

Source record↗