Algeria Biorisk Management Trainer Development Program - Workshop Introduction - April 2014.
Abstract not provided.
Brodsky, Benjamin H↗
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Results for “Program Development”
Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Nuclear Security Applications Research & Development Program Review NSARD 2019 Interdependent Networks (iNets)
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97 MATHEMATICS AND COMPUTING↗
Mk21 Fuze Program Development Reentry Vehicle Ground Testing.
Abstract not provided.
Dowdle, Donald Ryan↗
Strategies for Managing Unique Waste Streams Resulting from Heavy Isotope Production and Advanced Fuel Cycle Development Programs at ORNL
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Hylton, Tom↗
Enterprise SRS: leveraging ongoing operations to advance nuclear fuel cycles research and development programs
The Savannah River Site (SRS) is re-purposing its vast array of assets (including H Canyon - a nuclear chemical separation plant) to solve issues regarding advanced nuclear fuel cycle technologies, nuclear materials processing, packaging, storage and disposition. The vehicle for this transformation is Enterprise SRS which presents a new, radical view of SRS as a united endeavor for 'all things nuclear' as opposed to a group of distinct and separate entities with individual missions and organizations. Key among the Enterprise SRS strategic initiatives is the integration of research into SRS facilities but also in other facilities in conjunction with on-going missions to provide researchers from other national laboratories, academic institutions, and commercial entities the opportunity to demonstrate their technologies in a relevant environment and scale prior to deployment. To manage that integration of research demonstrations into site facilities, a center for applied nuclear materials processing and engineering research has been established in SRS.
11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
SMART – A Comprehensive Research and Development Program to Demonstrate Application of Machine Learning for Supporting CCS Deployment
The objective of the US Department of Energy’s SMART Initiative, i.e., Science-informed Machine Learning (ML) for Accelerating Real-Time Decisions in Subsurface Applications, is to showcase how the utilization of ML can significantly improve efficiency and effectiveness of field-scale commercial carbon storage operations. This paper will present the results from the current phase of SMART (field deployment) for demonstrating the applicability of ML-based tools and workflows for: (a) virtual learning during the pre-injection permitting phase, (b) advanced storage reservoir imaging to better characterize fractures and faults, and (c) dynamic storage reservoir modelling and optimization to inform operational decision making and visualization of system evolution.
Siriwardane, Hema↗
Technical Approach for Determining Key Parameters Needed for Modeling the Performance of Cast Stone for the Integrated Disposal Facility Performance Assessment
Washington River Protection Solutions (WRPS) and its contractors at Pacific Northwest National Laboratory (PNNL) and Savannah River National Laboratory (SRNL) are conducting a development program to develop / refine the cementitious waste form for the wastes treated at the ETF and to provide the data needed to support the IDF PA. This technical approach document is intended to provide guidance to the cementitious waste form development program with respect to the waste form characterization and testing information needed to support the IDF PA. At the time of the preparation of this technical approach document, the IDF PA effort is just getting started and the approach to analyze the performance of the cementitious waste form has not been determined. Therefore, this document looks at a number of different approaches for evaluating the waste form performance and describes the testing needed to provide data for each approach. Though the approach addresses a cementitious secondary aqueous waste form, it is applicable to other waste forms such as Cast Stone for supplemental immobilization of Hanford LAW. The performance of Cast Stone as a physical and chemical barrier to the release of contaminants of concern (COCs) from solidification of Hanford liquid low activity waste (LAW) and secondary wastes processed through the Effluent Treatment Facility (ETF) is of critical importance to the Hanford Integrated Disposal Facility (IDF) total system performance assessment (TSPA). The effectiveness of cementitious waste forms as a barrier to COC release is expected to evolve with time. PA modeling must therefore anticipate and address processes, properties, and conditions that alter the physical and chemical controls on COC transport in the cementitious waste forms over time. Most organizations responsible for disposal facility operation and their regulators support an iterative hierarchical safety/performance assessment approach with a general philosophy that modeling provides the critical link between the short-term understanding from laboratory and field tests, and the prediction of repository performance over repository time frames and scales. One common recommendation is that experiments be designed to permit the appropriate scaling in the models. There is a large contrast in the physical and chemical properties between the Cast Stone waste package and the IDF backfill and surrounding sediments. Cast Stone exhibits low permeability, high tortuosity, low carbonate, high pH, and low Eh whereas the backfill and native sediments have high permeability, low tortuosity, high carbonate, circumneutral pH, and high Eh. These contrasts have important implications for flow, transport, and reactions across the Cast Stone – backfill interface. Over time with transport across the interface and subsequent reactions, the sharp geochemical contrast will blur and there will be a range of spatially-distributed conditions. In general, COC mobility and transport will be sensitive to these geochemical variations, which also include physical changes in porosity and permeability from mineral reactions. Therefore, PA modeling must address processes, properties, and conditions that alter the physical and chemical controls on COC transport in the cementitious waste forms over time. Section 2 of this document reviews past Hanford PAs and SRS Saltstone PAs, which to date have mostly relied on the lumped parameter COC release conceptual models for TSPA predictions, and provides some details on the chosen values for the lumped parameters. Section 3 provides more details on the hierarchical modeling strategy and processes and mechanisms that control COC release. Section 4 summarizes and lists the key parameters for which numerical values are needed to perform PAs. Section 5 provides brief summaries of the methods used to measure the needed parameters and references to get more details.
12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
Advanced Hydrogen Turbine Development
Under the sponsorship of the U.S. Department of Energy (DOE) National Energy Technology Laboratories, Siemens has completed the Advanced Hydrogen Turbine Development Program to develop an advanced gas turbine for incorporation into future coal-based Integrated Gasification Combined Cycle (IGCC) plants. All the scheduled DOE Milestones were completed and significant technical progress was made in the development of new technologies and concepts. Advanced computer simulations and modeling, as well as subscale, full scale laboratory, rig and engine testing were utilized to evaluate and select concepts for further development. Program Requirements of: A 3 to 5 percentage point improvement in overall plant combined cycle efficiency when compared to the reference baseline plant; 20 to 30 percent reduction in overall plant capital cost when compared to the reference baseline plant; and NOx emissions of 2 PPM out of the stack. were all met. The program was completed on schedule and within the allotted budget
42 ENGINEERING↗
Development and implementation of energy efficiency standards and labeling programs in China: Progress and challenges
Over the last twenty years, with growing policy emphasis on improving energy efficiency and reducing environmental pollution and carbon emissions, China has implemented a series of new minimum energy performance standards (MEPS) and mandatory and voluntary energy labels to improve appliance energy efficiency. As China begins planning for the next phase of standards and labeling (S&L) program development under the 12th Five Year Plan, an evaluation of recent program developments and future directions is needed to identify gaps that still exist when compared with international best practices. The review of China’s S&L program development and implementation in comparison with major findings from international experiences reveal that there are still areas of improvement, particularly when compared to success factors observed across leading international S&L program. China currently lacks a formalized regulatory process for standard-setting and do not have any legal or regulatory guidance on elements of S&L development such as stakeholder participation or the issue of legal precedence between conflicting national, industrial and local standards. Consequently, China’s laws regarding standard-setting and management of the mandatory energy label program could be updated, as they have not been amended or revised recently and no longer reflects the current situation. While China uses similar principles for choosing target products as the U.S., Australia, EU and Japan, including high energy-consumption, mature industry and testing procedure and stakeholder support, recent MEPS revisions have generally aimed at only eliminating the bottom 20% efficiency of the market. Setting a firm principle based on maximizing energy savings that are technically feasible and economically justified may help improve the stringency of China’s MEPS program and reduce the need for frequent revisions. China also lacks robust survey data and relies primarily on market research data in relatively simple techno-economic analyses used to determine its efficiency standards levels rather than the specific sets of analyses and tools used internationally. Based on international experiences, inclusion of more detailed energy consumption surveys in the Chinese national census surveys and statistical reporting systems could help provide the necessary data for more comprehensive standard-setting analyses. In terms of stakeholder participation in the standards development process, stakeholder participation in China is limited to membership on technical committees responsible for developing or revising standards and generally do not include environmental groups, consumer associations, utilities and other NGOs. Increasing stakeholder involvement to broader interest groups could help garner more support and feedback in the S&L implementation process. China has emerged as a leader in a national verification testing scheme with complementary pilot checktesting projects, but it still faces challenges with insufficient funding, low local awareness amongst some regulatory agencies and resistance to check-testing by some manufacturers, limited product sampling scope, and testing inconsistency and incomparability of results. Thus, further financial and staff resources and capacity building will be needed to overcome these remaining challenges and to expand impacts evaluations to assess the actual effectiveness of implementation and enforcement.
29 ENERGY PLANNING, POLICY, AND ECONOMY↗
DOE-NE Light Water Reactor Sustainability Program and EPRI Long-Term Operations Program. Joint Research and Development Plan
Nuclear power has contributed almost 20% of the total amount of electricity generated in the United States over the past two decades. High capacity factors and low operating costs make nuclear power plants (NPPs) some of the most economical power generators available. Further, nuclear power remains the single largest contributor (nearly 70%) of non-greenhouse gas-emitting electric power generation in the United States. Even when major refurbishments are performed to extend operating life, these plants continue to represent cost-effective, low-carbon assets to the nation’s electrical generation capability. By the end of 2014, about one-third of the existing domestic fleet will have passed their 40th anniversary of power operations, and about one-half of the fleet will reach the same 40-year mark within this decade. Recognizing the challenges associated with pursuing extended service life of commercial nuclear power plants, the U.S. Department of Energy’s (DOE) Office of Nuclear Energy (NE) and the Electric Power Research Institute (EPRI) have established separate but complementary research and development programs (DOE-NE’s Light Water Reactor Sustainability [LWRS] Program and EPRI’s Long-Term Operations [LTO] Program) to address these challenges. To ensure that a proper linkage is maintained between the programs, DOE-NE and EPRI executed a memorandum of understanding in late 2010 to “establish guiding principles under which research activities (between LWRS and LTO) could be coordinated to the benefit of both parties.” This document represents the third annual revision to the initial version (March 2011) of the plan as called for in the memorandum of understanding.
22 GENERAL STUDIES OF NUCLEAR REACTORS↗
Los Alamos National Laboratory Double Shell Program Target Development
The Double Shell Program at Los Alamos National Laboratory is studying an alternative platform for achieving robust alpha-particle heating at the National Ignition Facility. Double shells benefit from having a low convergence ratio and lower predicted temperature for achieving volume ignition. The joint required to assemble a double shell has an imperfection in the outer shell that seeds instabilities that can greatly impact the inner capsule’s implosion at bang time. Furthermore, different variations of the shape and placement of the joint were implemented with improvements in the quality of the machining leading to measurable improvements in yield. High-Z coatings on the outer joint mitigated the impact of the 1- to 2-μm gap sometimes found in double shell assemblies.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
Dose-finding studies in drug development for rare genetic diseases
The small patient populations inherent to rare genetic diseases present many challenges to the traditional drug development paradigm. One major challenge is generating sufficient data in early phase studies to inform dose selection for later phase studies and dose optimization for clinical use of the drug. However, optimizing the benefit-risk profile of drugs through appropriate dose selection during drug development is critical for all drugs, including those being developed to treat rare diseases. Recognizing the challenges of conducting dose finding studies in rare disease populations and the importance of dose selection and optimization for successful drug development, we assessed the dose-finding studies and analyses conducted for drugs recently approved for rare genetic diseases. Of the 40 marketing applications for new molecular entity (NME) drugs and biologics approved by the United States Food and Drug Administration for rare genetic diseases from 2015 to 2020, 21 (53%) of the development programs conducted at least one dedicated dose-finding study. In addition, the majority of drug development programs conducted clinical studies in healthy subjects and included population pharmacokinetic and exposure–response analyses; some programs also conducted clinical studies in patient populations other than the disease for which the drug was initially approved. The majority of primary endpoints utilized in dedicated dose-finding studies were biomarkers, and the primary endpoint of the safety and efficacy study matched the primary endpoint used in the dose finding study in 9 of 13 (69%) drug development programs where primary study endpoints were assessed. Our study showed that NME drug development programs for rare genetic diseases utilize multiple data sources for dosing information, including studies in healthy subjects, population pharmacokinetic analyses, and exposure–response analyses. In addition, our results indicate that biomarkers play a key role in dose-finding studies for rare genetic disease drug development programs. Our findings highlight the need to develop study designs and methods to allow adequate dose-finding efforts within rare disease drug development programs that help overcome the challenges presented by low patient prevalence and other factors. Furthermore, the frequent reliance on biomarkers as endpoints for dose-finding studies underscores the importance of biomarker development in rare diseases.
60 APPLIED LIFE SCIENCES↗
Monolithic U-10Mo Fuel Development for U.S. High Performance Research Reactors
To support the U.S Department of Energy (DOE), National Nuclear Security Administration (NNSA) mission to reduce the threat posed by the civilian use of highly enriched uranium (HEU) worldwide, the US High Performance Research Reactor (US HPRR) fuel development program is pursuing development and qualification of a new high-density monolithic U-Mo fuel to facilitate conversion of five higher power research reactors located in the U.S. (ATR, HFIR, NBSR, MIT and MURR) and one critical facility (ATR-C) from HEU to low enriched uranium (LEU). These reactors require higher uranium fuel density than is achievable with dispersion fuel systems used to convert lower power research reactors. The down selected fuel system consists of U-10Mo alloy fuel foils having a thin Zr diffusion barrier interlayer, clad in 6061 Al alloy by hot isostatic pressing. In order to support fabrication development, fuel performance evaluations, generic fuel qualification through the Nuclear Regulatory Commission (NRC), and eventual reactor licensing, a series of irradiation experiments and testing campaigns are being planned. The tests are designed to provide data needed for fabrication process down selection, to establish acceptable fuel performance under normal operating conditions and anticipated transients, and to demonstrate successful scale-up to prototypic reactor-specific fuel element designs. A comprehensive testing program is being executed as part of the US HPRR fuel development program to develop and qualify a new monolithic UMo fuel system to allow conversion of five high power research reactors and one critical facility within the US in support of the NNSA mission to convert research reactors worldwide from HEU to LEU fuels. A significant outcome of this program will be the qualification and eventual licensing of a new plate-type fuel system for use in research reactors through the NRC for the first time in nearly 3 decades. (authors)
11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
Solar Energy Technologies Office Workforce Request for Information and Convenings (Summary)
On May 4, 2021, the U.S. Department of Energy (DOE) Solar Energy Technologies Office (SETO) published a Request for Information (RFI) on programs that support the development of a diverse and skilled clean energy workforce. The purpose of the RFI was to solicit feedback from industry, academia, government agencies, worker organizations (including unions), and other stakeholders on issues related to the employment needs of the solar industry, and the perceived value of different workforce development programs, training strategies, and tools. To supplement the RFI, SETO hosted four virtual convenings that brought together the utility-scale solar industry, the distributed generation solar industry, and labor and other workforce training organizations to hear direct feedback on the questions in the RFI. In addition, SETO held listening sessions with about a dozen other organizations and staff who could not participate in the virtual convenings. Altogether, SETO received 45 responses from the RFI and heard directly from 80-100 other stakeholders via the convenings and listening sessions. This document summarizes the stakeholder feedback that SETO received as a result of this process. While both the RFI and convening series were focused on solar deployment and solar industry members, much of this information is relevant across clean energy technologies and programs. It is important to recognize that DOE is intentionally reviewing our workforce development programming and support to focus on clean energy careers more holistically.
14 SOLAR ENERGY↗
An Integrated Development Environment for Adiabatic Quantum Programming
Adiabatic quantum computing is a promising route to the computational power afforded by quantum information processing. The recent availability of adiabatic hardware raises the question of how well quantum programs perform. Benchmarking behavior is challenging since the multiple steps to synthesize an adiabatic quantum program are highly tunable. We present an adiabatic quantum programming environment called JADE that provides control over all the steps taken during program development. JADE captures the workflow needed to rigorously benchmark performance while also allowing a variety of problem types, programming techniques, and processor configurations. We have also integrated JADE with a quantum simulation engine that enables program profiling using numerical calculation. The computational engine supports plug-ins for simulation methodologies tailored to various metrics and computing resources. We present the design, integration, and deployment of JADE and discuss its use for benchmarking adiabatic quantum programs.
ISING MODEL↗
NEET Enhanced Micro-Pocket Fission Detector for High Temperature Reactors - FY16 Status Report
A collaboration between the Idaho National Laboratory (INL), the Kansas State University (KSU), and the French Atomic Energy Agency, Commissariat à l'Énergie Atomique et aux Energies Alternatives, (CEA), has been initiated by the Nuclear Energy Enabling Technologies (NEET) Advanced Sensors and Instrumentation (ASI) program for developing and testing High Temperature Micro-Pocket Fission Detectors (HT MPFD), which are compact fission chambers capable of simultaneously measuring thermal neutron flux, fast neutron flux and temperature within a single package for temperatures up to 800 °C. The MPFD technology utilizes a small, multi-purpose, robust, in-core fission chambers and thermocouple. As discussed within this report, the small size, variable sensitivity, and increased accuracy of the MPFD technology represent a revolutionary improvement over current methods used to support irradiations in US Material Test Reactors (MTRs). Previous research conducted through NEET ASI1-3 has shown that the MPFD technology could be made robust and was successfully tested in a reactor core. This new project will further the MPFD technology for higher temperature regimes and other reactor applications by developing a HT MPFD suitable for temperatures up to 800 °C. This report summarizes the research progress for year two of this three year project. Highlights from research accomplishments include: • Continuation of a joint collaboration between INL, KSU, and CEA. Note that CEA is participating at their own expense because of interest in this unique new sensor. • An updated parallel wire HT MPFD design was developed. • Program support for HT MPFD deployments was given to Accident Tolerant Fuels (ATF) and Advanced Gas-cooled Reactor (AGR) irradiation test programs. • Quality approved materials for HT MPFD construction were procured by irradiation test programs for upcoming deployments. • KSU improved and performed electrical contact and fissile material plating. • KSU delivered fissile HT MPFD parts to INL for final construction of HT MPFD prototype. • A prototype HT MPFD was constructed and analyzed at INL. • The HT MPFD has been modeled in MCNP to optimize the amount of fissile material deposition. • The HT MPFD has been modeled in MCNP to optimize the sensor location in the irradiation test. • The fissile material deposition is undergoing independent verifications. • Detector amplifier electronics have been revised and tested by KSU. • Several project meetings were held at INL and KSU to discuss the roles and responsibilities between INL, KSU, and CEA for development and deployment of the HT MPFDs. As documented in this report, FY16 funding has allowed the project to meet year two planned accomplishments to develop a HT MPFD. In addition, the accomplishments of this project have attracted independent funding from other Department of Energy Office of Nuclear Energy (DOE-NE) programs for MTR irradiations of the MPFD technology. These are significant opportunities for this NEET Enhanced Micro-Pocket Fission Detector for High Temperature Reactors project because the irradiation expense of these experiments could not be included in the original project scope.
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
Signal Studies, Algorithms & Methods (SSAM) project summary slide for Nuclear Security Application Research and Development 2017 Program Review
Annual NA-22/DNN Nuclear Security Application Research and Development (NSARD) Program Review Meeting, hosted at NFO (Losee Road) in Las Vegas, NV April 4-6, 2017. Each project must present a summary slide.
98 NUCLEAR DISARMAMENT, SAFEGUARDS, AND PHYSICAL P↗