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At least 163 records · Page 9
All sourcesNASA NTRSDOE OSTI
NASA NTRS1988

Kidney cell electrophoresis in space flight: Rationale, methods, results and flow cytometry applications

Cultures of human embryonic kidney cells consistently contain an electrophoretically separable subpopulation of cells that produce high levels of urokinase and have an electrophoretic mobility about 85 percent as high as that of the most mobile human embryonic kidney cells. This subpopulation is rich in large epithelioid cells that have relatively little internal structure. When resolution and throughput are adequate, free fluid electrophoresis can be used to isolate a broad band of low mobility cells which also produces high levels of plasminogen activators (PAs). In the course of performing this, it was discovered that all electrophoretic subpopulations of cultured human embryonic kidney cells produce some PAs and that separate subpopulations produce high quantities of different types of PA's. This information and the development of sensitive assays for this project have provided new insights into cell secretion mechanisms related to fibrinolysis. These advances would probably not have been made without the NASA program to explore fundamental questions of free fluid electrophoresis in space.

Todd, P.↗
NASA NTRS1990

Autoclavable addition polyimides for 371 C composite applications

Studies were conducted to improve the thermo-oxidative stability (TOS) of PMR type polyimides by the substitution of para-aminostyrene (PAS) for the nadic ester endcap in second generation PMR polyimides (PMR-2). The nadic endcap which provides the PMR polyimides with their relative ease of fabrication, both by limiting the molecular weight of the prepolymer and by undergoing the final addition cure without volatiles, is also the weak link with regard to TOS. A polyimide formulated with PAS endcaps, called V-CAP, utilizes a two step reaction sequence similar to that of the PMR polyimides and can be easily autoclave molded into low void composite materials. Resin studies included two formulations of both PMR-2 and V-CAP, corresponding to n=9 and n=14 prepolymer stoichiometry. Unidirectional reinforced T40R graphite fiber laminates were fabricated from each of the resins was post-cured in either air at 385 C or nitrogen at 400 C. Composite specimens were aged in air at 371 C and mechanical properties were measured at 371 C before and after exposure.

Vannucci, R. D.↗
NASA NTRS1989

A review and update of the NASA aircraft noise prediction program propeller analysis system

The National Aeronautics and Space Administration (NASA) Aircraft Noise Prediction Program (ANOPP) Propeller Analysis System (PAS) is a set of computational modules for predicting the aerodynamics, performance, and noise of propellers. The ANOPP PAS has the capability to predict noise levels for propeller aircraft certification and produce parametric scaling laws for the adjustment of measured data to reference conditions. A technical overview of the prediction techniques incorporated into the system is presented. The prediction system has been applied to predict the noise signature of a variety of propeller configurations including the effects of propeller angle of attack. A summary of these validation studies is discussed with emphasis being placed on the wind tunnel and flight test programs sponsored by the Federal Aviation Administration (FAA) for the Piper Cherokee Lance aircraft. A number of modifications and improvements have been made to the system and both DEC VAX and IBM-PC versions of the system have been added to the original CDC NOS version.

Golub, Robert A.↗
NASA NTRS1990

Autoclavable addition polyimides for 371 C composite applications

Studies were conducted to improve the thermo-oxidative stability (TOS) of PMR type polyimides by the substitution of para-aminostyrene (PAS) for the nadic ester endcap in second generation PMR polyimides (PMR-2). The nadic endcap which provides the PMR polyimides with their relative ease of fabrication, both by limiting the molecular weight of the prepolymer and by undergoing the final addition cure without volatiles, is also the weak link with regard to TOS. A polyimide formulated with PAS endcaps, called V-CAP, utilizes a two step reaction sequence similar to that of the PMR polyimides and can be easily autoclave molded into low void composite materials. Resin studies included two formulations of both PMR-2 and V-CAP, corresponding to n = 9 and n = 14 prepolymer stoichiometry. Unidirectional reinforced T40R graphite fiber laminates were fabricated from each of the resins was post-cured in either air at 385 C or nitrogen at 400 C. Composite specimens were aged in air at 371 C and mechanical properties were measured at 371 C before and after exposure.

Vannucci, R. D.↗
NASA NTRS1992

Slow-Positron Generator For Studying Polymer Films

Aspects of molecular structures probed by positron-annihilation spectroscopy (PAS). Slow-positron-beam generator suitable for PAS measurements in thin polymer films. Includes Na22 source of positrons and two moderators made of well-annealed tungsten foil. With proper choice of voltage, positrons emitted by inward-facing surfaces of moderators made to stop in polymer films tested.

Singh, Jag J.↗
NASA NTRS1994

Improved PMR Polyimides For Heat-Stable Laminates

Second-generation PMR-type polyimides (PMR-II polyimides) of enhanced thermo-oxidative stability prepared by substitution of para-aminostyrene (PAS) end caps for nadic-ester (NE) end caps used in prior PMR-II polyimides. Laminates unidirectionally reinforced with graphite fibers and made with PAS-capped resins exhibited thermo-oxidative stabilities significantly greater than those of similar laminates made with NE-capped PMR-II resins. One new laminate exhibited high retention of weight and strength after 1,000 h of exposure to air at 371 degrees C.

Vannucci, R. D.↗
NASA NTRS1993

Mission planning for Shuttle Imaging Radar-C (SIR-C) with a real-time interactive planning software

The Shuttle Imaging Radar-C (SIR-C) mission will operate from the payload bay of the space shuttle for 8 days, gathering Synthetic Aperture Radar (SAR) data over specific sites on the Earth. The short duration of the mission and the requirement for realtime planning offer challenges in mission planning and in the design of the Planning and Analysis Subsystem (PAS). The PAS generates shuttle ephemerides and mission planning data and provides an interactive real-time tool for quick mission replanning. It offers a multi-user and multiprocessing environment, and it is able to keep multiple versions of the mission timeline data while maintaining data integrity and security. Its flexible design allows one software to provide different menu options based on the user's operational function, and makes it easy to tailor the software for other Earth orbiting missions.

Potts, Su K.↗
NASA NTRS1995

USML-1 microgravity glovebox experiment no. 1 Passive Accelerometer System

The passive accelerometer system (PAS) is a simple moving ball accelerometer capable of measuring the small magnitude steady relative acceleration that occurs in a low earth orbit spacecraft due to atmospheric drag and the earth's gravity gradient. The accelerometer can be used when the spacecraft continuously rotates during the orbit such that some line of reference in the craft always points along the vector connecting the earth's mass center with the spacecraft mass center. PAS was used successfully on the first United States Microgravity Laboratory (USML-1).

Alexander, J. Iwan D.↗
NASA NTRS2001

Passive and Active Stabilization of Liquid Bridges in Low Gravity

Tests are planned in the low gravity environment of the International Space Station (ISS) of new methods for the suppression of the capillary instability of liquid bridges. Our suppression methods are unusual in that they are not limited to liquid bridges having very special properties and may impact a variety of low-gravity and earth-based technologies. There are two main approaches to be investigated: (1) Passive Acoustic Stabilization (PAS); and (2) Active Electrostatic Stabilization (AES). In PAS, the suppression of the mode growth is accomplished by placing the bridge in an acoustic field having the appropriate properties such that the acoustic radiation pressure automatically pulls outward on the thinnest portion of the bridge. In AES, the bridge deformation is sensed optically and counteracted by actively adjusting the electrostatic Maxwell stresses via two ring electrodes concentric with the slightly conducting bridge to offset the growth of the unstable mode. While the present work emphasizes cylindrical bridges, the methods need not be restricted to that case. The methods to be explored are relevant to the suppression of capillary instabilities in floating zone crystal growth, breakup of liquid jets and columns, bubbles, and annular films as well as the management of coolants or propellants in low-gravity.

Marston, Philip L.↗
NASA NTRS2002

Impaired pulmonary artery contractile responses in a rat model of microgravity: role of nitric oxide

Vascular contractile hyporesponsiveness is an important mechanism underlying orthostatic intolerance after microgravity. Baroreceptor reflexes can modulate both pulmonary resistance and capacitance function and thus cardiac output. We hypothesized, therefore, that pulmonary vasoreactivity is impaired in the hindlimb-unweighted (HLU) rat model of microgravity. Pulmonary artery (PA) contractile responses to phenylephrine (PE) and U-46619 (U4) were significantly decreased in the PAs from HLU vs. control (C) animals. N(G)-nitro-L-arginine methyl ester (10(-5) M) enhanced the contractile responses in the PA rings from both C and HLU animals and completely abolished the differential responses to PE and U4 in HLU vs. C animals. Vasorelaxant responses to ACh were significantly enhanced in PA rings from HLU rats compared with C. Moreover, vasorelaxant responses to sodium nitroprusside were also significantly enhanced. Endothelial nitric oxide synthase (eNOS) and soluble guanlyl cyclase expression were significantly enhanced in PA and lung tissue from HLU rats. In marked contrast, the expression of inducible nitric oxide synthase was unchanged in lung tissue. These data support the hypothesis that vascular contractile responsiveness is attenuated in PAs from HLU rats and that this hyporesponsiveness is due at least in part to increased nitric oxide synthase activity resulting from enhanced eNOS expression. These findings may have important implications for blood volume distribution and attenuated stroke volume responses to orthostatic stress after microgravity exposure.

Non-NASA Center↗
NASA NTRS2004

EXPRESS Pallet Payload Interface Requirements

A viewgraph presentation describing the EXPRESS Pallet Space Station payload interface requirements is shown. The topics include: 1) External Payload Sites; 2) EXPRESS Pallet with Six Payload Envelopes; 3) EXPRESS Pallet in Payload Bay Representative Layout; 4) EXPRESS Pallet Installation SSRMS positions pallet for PAS mating on S3 truss; 5) EXPRESS Pallet Major Components; 6) EXPRESS Pallet Adapter; 7) EXPRESS Pallet Center Location Payload Envelope; 8) Envelope Restriction for EXPRESS Pallet Corner Payload Locations; 9) EXPRESS Pallet-PAS Truss Configuration; and 10) EXPRESS Pallet Payload Services and Specifications.

Holt, Alan C.↗
NASA NTRS2004

Space Interferometry Mission Science Overview

Conclusions: SIM is on track for a launch in 2010. Project 'Phase C' start in October 2005. SIM is a flexibly-pointed instrument Astrometric capability (wide angle) a) 4 pas parallax precision on targets down to V = 20 = Stellar and Galactic astrophysics; and b) 1 pas single measurement accuracy. Sensitive to terrestrial-mass planets around the nearest stars New proposal opportunities are: a) AO-2 for new (large) Key projects - 2005; and b) General Observer program, for smaller proposals - 2006.

planet searching↗
NASA NTRS2010

338-GHz Semiconductor Amplifier Module

Research findings were reported from an investigation of new gallium nitride (GaN) monolithic millimeter-wave integrated circuit (MMIC) power amplifiers (PAs) targeting the highest output power and the highest efficiency for class-A operation in W-band (75-110 GHz). W-band PAs are a major component of many frequency multiplied submillimeter-wave LO signal sources. For spectrometer arrays, substantial W-band power is required due to the passive lossy frequency multipliers.

Samoska, Lorene A.↗
NASA NTRS2011

Power-Combined GaN Amplifier with 2.28-W Output Power at 87 GHz

Future remote sensing instruments will require focal plane spectrometer arrays with higher resolution at high frequencies. One of the major components of spectrometers are the local oscillator (LO) signal sources that are used to drive mixers to down-convert received radio-frequency (RF) signals to intermediate frequencies (IFs) for analysis. By advancing LO technology through increasing output power and efficiency, and reducing component size, these advances will improve performance and simplify architecture of spectrometer array systems. W-band power amplifiers (PAs) are an essential element of current frequency-multiplied submillimeter-wave LO signal sources. This work utilizes GaN monolithic millimeter-wave integrated circuit (MMIC) PAs developed from a new HRL Laboratories LLC 0.15- m gate length GaN semiconductor transistor. By additionally waveguide power combining PA MMIC modules, the researchers here target the highest output power performance and efficiency in the smallest volume achievable for W-band.

Fung, King Man↗
NASA NTRS2011

Constraining the Absolute Orientation of eta Carinae's Binary Orbit: A 3-D Dynamical Model for the Broad [Fe III] Emission

We present a three-dimensional (3-D) dynamical model for the broad [Fe III] emission observed in Eta Carinae using the Hubble Space Telescope/Space Telescope Imaging Spectrograph (HST/STIS). This model is based on full 3-D Smoothed Particle Hydrodynamics (SPH) simulations of Eta Car's binary colliding winds. Radiative transfer codes are used to generate synthetic spectro-images of [Fe III] emission line structures at various observed orbital phases and STIS slit position angles (PAs). Through a parameter study that varies the orbital inclination i, the PA(theta) that the orbital plane projection of the line-of-sight makes with the apastron side of the semi-major axis, and the PA on the sky of the orbital axis, we are able, for the first time, to tightly constrain the absolute 3-D orientation of the binary orbit. To simultaneously reproduce the blue-shifted emission arcs observed at orbital phase 0.976, STIS slit PA = +38deg, and the temporal variations in emission seen at negative slit PAs, the binary needs to have an i approx. = 130deg to 145deg, Theta approx. = -15deg to +30deg, and an orbital axis projected on the sky at a P A approx. = 302deg to 327deg east of north. This represents a system with an orbital axis that is closely aligned with the inferred polar axis of the Homunculus nebula, in 3-D. The companion star, Eta(sub B), thus orbits clockwise on the sky and is on the observer's side of the system at apastron. This orientation has important implications for theories for the formation of the Homunculus and helps lay the groundwork for orbital modeling to determine the stellar masses.

Madura, T. I.↗
NASA NTRS2012

Ka-Band Waveguide Three-Way Serial Combiner for MMIC Amplifiers

In this innovation, the three-way combiner consists internally of two branch-line hybrids that are connected in series by a short length of waveguide. Each branch-line hybrid is designed to combine input signals that are in phase with an amplitude ratio of two. The combiner is constructed in an E-plane split-block arrangement and is precision machined from blocks of aluminum with standard WR-28 waveguide ports. The port impedances of the combiner are matched to that of a standard WR-28 waveguide. The component parts include the power combiner and the MMIC (monolithic microwave integrated circuit) power amplifiers (PAs). The three-way series power combiner is a six-port device. For basic operation, power that enters ports 3, 5, and 6 is combined in phase and appears at port 1. Ports 2 and 4 are isolated ports. The application of the three-way combiner for combining three PAs with unequal output powers was demonstrated. NASA requires narrow-band solid-state power amplifiers (SSPAs) at Ka-band frequencies with output power in the range of 3 to 5 W for radio or gravity science experiments. In addition, NASA also requires wideband, high-efficiency SSPAs at Ka-band frequencies with output power in the range of 5 to 15 W for high-data-rate communications from deep space to Earth. The three-way power combiner is designed to operate over the frequency band of 31.8 to 32.3 GHz, which is NASA s deep-space frequency band.

Wintucky, Edwin G.↗
NASA NTRS2014

Power, Avionics and Software Communication Network Architecture

This document describes the communication architecture for the Power, Avionics and Software (PAS) 2.0 subsystem for the Advanced Extravehicular Mobile Unit (AEMU). The following systems are described in detail: Caution Warn- ing and Control System, Informatics, Storage, Video, Audio, Communication, and Monitoring Test and Validation. This document also provides some background as well as the purpose and goals of the PAS project at Glenn Research Center (GRC).

Avionics↗
NASA NTRS2014

A Communication Architecture for an Advanced Extravehicular Mobile Unit

This document describes the communication architecture for the Power, Avionics and Software (PAS) 1.0 subsystem for the Advanced Extravehicular Mobility Unit (AEMU). The following systems are described in detail: Caution Warning and Control System, Informatics, Storage, Video, Audio, Communication, and Monitoring Test and Validation. This document also provides some background as well as the purpose and goals of the PAS subsystem being developed at Glenn Research Center (GRC).

Avionics↗