Differential exposure and acute health impacts of inhaled solid-fuel emissions from rudimentary and advanced cookstoves in female CD-1 mice
Highlights: • Mice inhaled emissions from advanced cookstoves (CS) and a 3-stone (3-S)-fire. • Tier 2 and 3 CS emitted significantly less particulate matter and carbon monoxide. • 3-S fire (Tier 0)-exposed mice were the only group to develop acute lung injury. • Diminished macrophage phagocytosis was observed in Tier 2 CS-exposed mice. • Lung glutathione was significantly depleted across all Tier 0–3 CS-exposed mice. There is an urgent need to provide access to cleaner end user energy technologies for the nearly 40% of the world's population who currently depend on rudimentary cooking and heating systems. Advanced cookstoves (CS) are designed to cut emissions and solid-fuel consumption, thus reducing adverse human health and environmental impacts.