[beta]-diopside, a new ultrahigh-pressure polymorph of CaMgSi[subscript 2]O[subscript 6] with six-coordinated silicon
Abstract not provided
SEARCH · Engineering Papers
Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
Abstract not provided
Abstract not provided
Abstract not provided
Development of two innovative linacs is discussed. (1)High-efficiency normal-conducting accelerating structures for ions with beam velocities in the range of a few percent of the speed of light. Two existing accelerator technologies - the H-mode resonator cavities and transverse beam focusing by permanent-magnet quadrupoles (PMQ) - are merged to create efficient structures for light-ion beams of considerable currents. The inter-digital H-mode accelerator with PMQ focusing (IH-PMQ) has the shunt impedance 10-20 times higher than the standard drift-tube linac. Results of the combined 3-D modeling for an IH-PMQ accelerator tank - electromagnetic computations, beam-dynamics simulations, and thermal-stress analysis - are presented. H-PMQ structures following a short RFQ accelerator can be used in the front end of ion linacs or in stand-alone applications like a compact mobile deuteron-beam accelerator up to a few MeV. (2)A large-acceptance high-gradient linac for accelerating low-energy muons in a strong solenoidal magnetic field. When a proton beam hits a target, many low-energy pions are produced almost isotropically, in addition to a small number of high-energy pions in the forward direction. We propose to collect and accelerate copious muons created as the low-energy pions decay. The acceleration should bring muons to a kinetic energy of {approx}200 MeV in about 10 m, where both an ionization cooling of the muon beam and its further acceleration in a superconducting linac become feasible. One potential solution is a normal-conducting linac consisting of independently fed 0-mode RF cavities with wide apertures closed by thin metal windows or grids. The guiding magnetic field is provided by external superconducting solenoids. The cavity choice, overall linac design considerations, and simulation results of muon acceleration are presented. Potential applications range from basic research to homeland defense to industry and medicine.
The nonlinear co-existence of β–induced Alfvén eigenmode (BAE) and β–induced Alfvén-acoustic eigenmode (BAAE) is found in simulations using the gyrokinetic toroidal code, which provides a new mechanism responsible for BAAE excitation in tokamaks. In this work, the normalized pressure β is the ratio between plasma thermal pressure and magnetic pressure. The nonlinear simulation findings show that the BAAE branch emerges after the BAE branch is saturated. The mode structure's evolution shows that existence of BAAE will change the original BAE mode structure. The perturbed distribution functions in the velocity phase space show that a new resonance region manifesting the wave-particle resonance in the BAAE branch appears during the nonlinear co-existence stage.
Here, retrospective dose assessment following acute radiation exposures during radiological incidents can be difficult and inaccurate due to the large uncertainties associated with dose estimation. However, rapid and accurate dose assessment is critical following an incident, such that appropriate treatment can be provided to the patient as early as possible. Incident Dose assessment relies heavily on biological dosimetry with corresponding large uncertainties for inhomogeneous exposures, resulting from the estimates of whole-body doses, while the assessment of absorbed doses to individual tissues might actually be more appropriate for acute radiation exposures.
Abstract Not Provided
As part of the High-Luminosity Large Hadron Collider (LHC) Project, a set of Nb 3 Sn quadrupoles are being developed, aiming to enhance the performance of the inner triplets. The new magnets, identified as MQXFA and MQXFB, will share the same cross section with two different lengths, 4.2 and 7.2 m, respectively. During the magnet development, three short models were tested, along with a number of mechanical models, demonstrating the capability of the magnet cross section to achieve the specified performances. The same performances are now required for the full-length magnets. To ensure this, the authors studied the impact of the magnet length on the capability of the structure to provide an adequate support to the coils. Finite element and simplified analytical models were used to evaluate the impact of the magnet length on the stresses in the magnet ends and coil elongation during powering. Lastly, the models were calibrated using the results from the short model tests, and used to provide an indication on the required prestress and its foreseen impact on the magnet performance.
During the development of MQXF, the new Nb 3 Sn quadrupole to be used in the large hadron collider (LHC) inner triplets for the High Luminosity upgrade, three short models were tested: MQXFS1, MQXFS3, and MQXFS5. These models differ in the use of thin or thick laminations for the iron components, in the coil design, and in the superconductive strands, rod restack process (RRP) or powder in tube (PIT). In the MQXF design, the azimuthal prestress is provided at room temperature by means of the bladder-key technology, and it is further increased during the cooldown by the differential thermal contraction of the various components. Four aluminum rods provide the longitudinal prestress. Both systems allow for a flexible control of the amount of prestress applied. As a consequence, it was possible to test the models exploring different azimuthal and longitudinal prestress conditions, in an attempt to understand their impact on the magnet performances. Here, this paper studies the mechanical behavior of these short models, also providing the strain and stresses measured by means of strain gauges installed on the aluminum shell, on the winding poles and on the rods. Finally, the paper compares the measures with the results from finite element (FE) models.
For the High Luminosity Upgrade of the CERN Large Hadron Collider, lower * quadrupole magnets based on advanced Nb3Sn conductors will be installed on each side of the ATLAS and CMS experiment insertion zones. As part of the technological developments needed to achieve the required field gradient of 132.6 T/m within a 150-mm aperture, short length model magnets, named MQXFS, are tested both at the CERN SM18 and FERMI Lab test facilities. The model magnets rely on two types of Nb3Sn conductors (RRP and PIT) and on an innovative bladders and keys design to provide mechanical support against the Lorentz forces. In 2016 and 2017, the powering tests of the first two models MQXFS3 (RRP) and MQXFS5 (PIT) proved that nominal performance (16.5 kA) could be reached with excellent memory of the quench current after thermal cycle. However both magnets showed a slow training behavior with clear observations of voltage disturbances before the quench. Besides MQXFS5 only could reach ultimate current (17.9 kA) whereas erratic behavior was observed on MQXFS3 due to conductor local degradation at the head of one of the coil. In 2018, this limiting coil was changed and the applied azimuthal pre-stress increased. If ultimate current could then be reached, no stable current could be maintained due to identified defect on the outer layer of the new coil. Finally the outcome of the test of the new model MQXFS4, featuring the final RRP conductors that will be used for the series production and variation on the inner layer quench heater designs are here reported in details.
Abstract not provided
CUPID-Mo, located in the Laboratoire Souterrain de Modane (France), was a demonstrator for the next generation 0vββ decay experiment, CUPID. It consisted of an array of 20 enriched Li 2 100 MoO 4 bolometers and 20 Ge light detectors and has demonstrated that the technology of scintillating bolometers with particle identification capabilities is mature. Furthermore, CUPID-Mo can inform and validate the background prediction for CUPID. In this paper, we present a detailed model of the CUPID-Mo backgrounds. This model is able to describe well the features of the experimental data and enables studies of the 2vββ decay and other processes with high precision. We also measure the radio-purity of the Li 2 100 MoO 4 crystals which are found to be sufficient for the CUPID goals. Finally, we also obtain a background index in the region of interest of 3.7 $^{+0.9}_{-0.8}$ (stat) $^{+1.5}_{-0.7}$ (syst) x 10 -3 counts/ ΔE FWHM / mol iso / year the lowest in a bolometric Ovββ decay experiment.
One of the long-standing holy grails of molecular evolution has been the ability to predict an organism’s fitness directly from its genotype. With such predictive abilities in hand, researchers would be able to more accurately forecast how organisms will evolve and how proteins with novel functions could be engineered, leading to revolutionary advances in medicine and biotechnology. In this work, we assemble the largest reported set of experimental TEM-1 β-lactamase folding free energies and use this data in conjunction with previously acquired fitness data and computational free energy predictions to determine how much of the fitness of β-lactamase can be directly predicted by thermodynamic folding and binding free energies. We focus upon β-lactamase because of its long history as a model enzyme and its central role in antibiotic resistance. Based upon a set of 21 β-lactamase single and double mutants expressly designed to influence protein folding, we first demonstrate that modeling software designed to compute folding free energies such as FoldX and PyRosetta can meaningfully, although not perfectly, predict the experimental folding free energies of single mutants. Interestingly, while these techniques also yield sensible double mutant free energies, we show that they do so for the wrong physical reasons. We then go on to assess how well both experimental and computational folding free energies explain single mutant fitness. We find that folding free energies account for, at most, 24% of the variance in β-lactamase fitness values according to linear models and, somewhat surprisingly, complementing folding free energies with computationally-predicted binding free energies of residues near the active site only increases the folding-only figure by a few percent. This strongly suggests that the majority of β-lactamase’s fitness is controlled by factors other than free energies. Overall, our results shed a bright light on to what extent the community is justified in using thermodynamic measures to infer protein fitness as well as how applicable modern computational techniques for predicting free energies will be to the large data sets of multiply-mutated proteins forthcoming.
Explore the source record for details and available documents.