Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “profiling”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,603 records · Page 89
All sourcesNASA NTRSDOE OSTI
DOE OSTI2025

A novel closed-form inversion of the convection–diffusion equation for rapid convection, diffusion, and source profile estimation

To simplify and routinize particle transport analysis in fusion devices, a novel closed form linear inversion of the 1-D convection diffusion equation to estimate diffusion and convection profiles D(r ⃗ ), v(r ⃗ ) and source distribution s(r ⃗ ), of a single species from measured data is derived and demonstrated on synthetic data. Profile estimates of D(r ⃗ ), v(r ⃗ ), s(r ⃗ ) and their uncertainties are given as a matrix expression constructed directly from the incoming density data of the transported species in space and time, as well as physics assumptions such as particle conservation and experimental geometry. The derived matrix expression can be applied to a pumped or non-pumped recycling species, or a non-recycling species that is effectively “pumped” by plasma-facing surfaces.

Hinson, Edward [ORNL] (ORCID:000000019713140X)↗
DOE OSTI2025

Molybdenum density profiles in Alcator C-Mod plasmas

Molybdenum (Z = 42) density spatial profiles have been obtained for Alcator C-Mod L-, I-, and H-mode plasmas from x-ray observations of the neon-like Mo 32+ 4D transition. Profile shapes range from flat to modestly peaked in the core. The observed peaking factors for molybdenum are in good agreement with those calculated by TGLF across all confinement regimes, and there is little dependence seen with core density gradient, sawtooth amplitude, or rotation velocity. Predictions for tungsten peaking in SPARC are presented.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2014

Pyrethroid Activity-Based Probes for Profiling Cytochrome P450 Activities Associated with Insecticide Interactions

Pyrethroid insecticides are used to control a diverse spectrum of diseases spread by arthropods. We have developed a suite of pyrethroid mimetic activity based probes (PyABPs) to selectively label and identify P450s associated with pyrethroid metabolism. The probes were screened against pyrethroid metabolizing and non-metabolizing mosquito P450s, as well as rodent microsomes to measure labeling specificity, plus CPR and b5 knockout mouse livers to validate P450 activation and establish the role for b5 in probe activation. Using a deltamethrin mimetic PyABP we were able to profile active enzymes in rat liver microsomes and identify pyrethroid metabolizing enzymes in the target tissue. The most reactive enzyme was a P450, CYP2C11, which is known to metabolize deltamethrin. Furthermore, several other pyrethroid metabolizers were identified (CYPs 2C6, 3A4, 2C13 and 2D1) along with related detoxification enzymes, notably UDP-g’s 2B1 - 5, suggesting a network of associated pyrethroid metabolizing enzymes, or ‘pyrethrome’. Considering the central role that P450s play in metabolizing insecticides, we anticipate that PyABPs will aid the identification and profiling of P450s associated with insecticide pharmacology in a wide range of species, improving understanding of P450-insecticide interactions and aiding the development of new tools for disease control.

drug metabolism↗
DOE OSTI2016

Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors

Mutations conferring resistance to translation inhibitors often alter the structure of rRNA. Reduced susceptibility to distinct structural antibiotic classes may, therefore, emerge when a common ribosomal binding site is perturbed, which significantly reduces the clinical utility of these agents. The translation inhibitors negamycin and tetracycline interfere with tRNA binding to the aminoacyl-tRNA site on the small 30S ribosomal subunit. However, two negamycin resistance mutations display unexpected differential antibiotic susceptibility profiles. Mutant U1060A in 16S Escherichia coli rRNA is resistant to both antibiotics, whereas mutant U1052G is simultaneously resistant to negamycin and hypersusceptible to tetracycline. Using a combination of microbiological, biochemical, single-molecule fluorescence transfer experiments, and X-ray crystallography, we define the specific structural defects in the U1052G mutant 70S E. coli ribosome that explain its divergent negamycin and tetracycline susceptibility profiles. Unexpectedly, the U1052G mutant ribosome possesses a second tetracycline binding site that correlates with its hypersusceptibility. In conclusion, the creation of a previously unidentified antibiotic binding site raises the prospect of identifying similar phenomena in antibiotic-resistant pathogens in the future.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2013

ISOTHERMAL DISTRIBUTIONS IN MONDian GRAVITY AS A SIMPLE UNIFYING EXPLANATION FOR THE UBIQUITOUS{rho}{proportional_to}r {sup -3} DENSITY PROFILES IN TENUOUS STELLAR HALOS

That the stellar halo of the Milky Way has a density profile which, to first approximation, satisfies{rho}{proportional_to}r {sup -3} and has been known for a long time. More recently, it has become clear that M31 also has such an extended stellar halo, which approximately follows the same radial scaling. Studies of distant galaxies have revealed the same phenomenology. Also, we now know that the density profiles of the globular cluster systems of our Galaxy and Andromeda to first approximation follow{rho}{proportional_to}r {sup -3},{Sigma}{proportional_to}R {sup -2} in projection. Recently, diffuse populations of stars have been detected spherically surrounding a number of Galactic globular clusters, extending much beyond the Newtonian tidal radii, often without showing any evidence of tidal features. Within the standard Newtonian and general relativity scenario, numerous and diverse particular explanations have been suggested, individually tailored to each of the different classes of systems described above. Here we show that in a MONDian gravity scenario any isothermal tenuous halo of tracer particles forming a small perturbation surrounding a spherically symmetric mass distribution will have an equilibrium configuration which to first approximation satisfies a{rho}{proportional_to}r {sup -3} scaling.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2013

ASYMMETRIC ABSORPTION PROFILES OF Ly{alpha} AND Ly{beta} IN DAMPED Ly{alpha} SYSTEMS

Damped Ly{alpha} systems observed in the quasar spectra are characterized by a high neutral hydrogen column density, N{sub HI} > 2 x 10{sup 20} cm{sup -2}. The absorption wing profiles are often fitted using the Voigt function due to the fact that the scattering cross section near the resonant line center is approximately described by the Lorentzian function. Since a hydrogen atom has infinitely many p states that participate in the electric dipole interaction, the cross section starts to deviate from the Lorentzian in an asymmetric way in the line wing regions. We investigate this asymmetry in the absorption line profiles around Ly{alpha} and Ly{beta} as a function of the neutral hydrogen column density N{sub HI}. In terms of {Delta}{lambda} {identical_to} {lambda} - {lambda}{sub {alpha}}, we expand the Kramers-Heisenberg formula around Ly{alpha} to find {sigma}({lambda}) {approx_equal} (0.5f{sub 12}){sup 2}{sigma}{sub T}({Delta}{lambda}/{lambda}{sub {alpha}}){sup -2}[1 + 3.792({Delta}{lambda}/{lambda}{sub {alpha}})], where f{sub 12} and {sigma}{sub T} are the oscillator strength of Ly{alpha} and the Thomson scattering cross section, respectively. In terms of {Delta}{lambda}{sub 2} {identical_to} {lambda} - {lambda}{sub {beta}} in the vicinity of Ly{beta}, the total scattering cross section, given as the sum of cross sections for Rayleigh and Raman scattering, is shown to be {sigma}({lambda}) {approx_equal} {sigma}{sub T}(0.5f{sub 13}){sup 2}(1 + R{sub 0})({Delta}{lambda}{sub 2}/{lambda}{sub {beta}}){sup -2}[1 - 24.68({Delta}{lambda}{sub 2}/{lambda}{sub {beta}})] with f{sub 13} and the factor R{sub 0} = 0.1342 being the oscillator strength for Ly{beta} and the ratio of the Raman cross section to Rayleigh cross section, respectively. A redward asymmetry develops around Ly{alpha}, whereas a blue asymmetry is obtained for Ly{beta}. The absorption center shifts are found to be almost proportional to the neutral hydrogen column density.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2013

Calculated resonance line profiles of [Mg II], [C II], and [Si IV] in the solar atmosphere

NASA's Interface Region Imaging Spectrograph space mission, launched 2013 June 27, is intended to study the structure of the solar chromosphere and the transition region between the chromosphere and corona. The spectral lines to be observed include the Mg II k line at 2796.5 Å, the C II 1334.5 Å line, and the Si IV line at 1393.8 Å, which are formed in the middle chromosphere, the upper chromosphere, and the lower transition region, respectively. Here we calculate the profiles of these lines from four models of the solar atmosphere, intended to represent the faint and mean internetwork, a network lane, and bright network. We show how the profiles change from the center of the solar disk toward the limb of the Sun and in response to outflows and inflows. These results are intended to cover the range of expected quiet-Sun observations and assist in their interpretation. We expect that the observations will lead to improvements in the models, which can then be used to estimate the required non-radiative heating in the different regions.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2014

High energy emission of GRB 130821A: Constraining the density profile of the circum-burst medium as well as the initial Lorentz factor of the outflow

GRB 130821A was detected by Fermi-GBM/LAT, Konus-WIND, SPI-ACS/INTEGRAL, RHESSI and Mars Odyssey-HEND. Although the data of GRB 130821A are very limited, we show in this work that the high energy γ-ray emission (i.e., above 100 MeV) alone imposes tight constraint on the density profile of the circum-burst medium as well as the initial Lorentz factor of the outflow. The temporal behavior of the high energy γ-ray emission is consistent with the forward shock synchrotron radiation model, and the circum-burst medium likely has a constant-density profile. The Lorentz factor is about a few hundred, similar to other bright GRBs.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2014

RR Lyrae in XSTPS: The halo density profile in the north galactic cap

We present a catalog of RR Lyrae stars (RRLs) observed by the Xuyi Schmidt Telescope Photometric Survey (XSTPS). The area we consider is located in the north Galactic cap, covering ≈376.75 deg{sup 2} at α ≈ 150° and δ ≈ 27° down to a magnitude limit of i ≈ 19. Using the variability information afforded by the multi-epoch nature of our XSTPS data, combined with colors from the Sloan Digital Sky Survey, we are able to identify candidate RRLs. We find 318 candidates, derive distances to them, and estimate the detection efficiency. The majority of our candidates have more than 12 observations, and for these we are able to calculate periods. These also allow us to estimate our contamination level, which we predict is between 30% and 40%. Finally, we use the sample to probe the halo density profile in the 9-49 kpc range and find that it can be well fitted by a double power law. We find good agreement between this model and the models derived for the south Galactic cap using the Watkins et al. and Sesar et al. RRL data sets, after accounting for possible contamination in our data set from Sagittarius stream members. We consider non-spherical double power-law models of the halo density profile and again find agreement with literature data sets, although we have limited power to constrain the flattening due to our small survey area. Much tighter constraints will be placed by current and future wide-area surveys, most notably ESA's astrometric Gaia mission. Our analysis demonstrates that surveys with a limited number of epochs can effectively be mined for RRLs. Our complete sample is provided as accompanying online material; as an example the first few entries of each electronic table are shown in the text.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2014

Pulse profiles from spinning neutron stars in the Hartle-Thorne approximation

We present a new numerical algorithm for the calculation of pulse profiles from spinning neutron stars in the Hartle-Thorne approximation. Our approach allows us to formally take into account the effects of Doppler shifts and aberration, of frame dragging, as well as of the oblateness of the stellar surface and of its quadrupole moment. We confirm an earlier result that neglecting the oblateness of the neutron-star surface leads to ≅ 5%-30% errors in the calculated profiles and further show that neglecting the quadrupole moment of its spacetime leads to ≅ 1%-5% errors at a spin frequency of ≅ 600 Hz. We discuss the implications of our results for the measurements of neutron-star masses and radii with upcoming X-ray missions, such as NASA's NICER and ESA's LOFT.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2014

Constraining dark matter halo profiles and galaxy formation models using spiral arm morphology. II. Dark and stellar mass concentrations for 13 nearby face-on galaxies

We investigate the use of spiral arm pitch angles as a probe of disk galaxy mass profiles. We confirm our previous result that spiral arm pitch angles (P) are well correlated with the rate of shear (S) in disk galaxy rotation curves. We use this correlation to argue that imaging data alone can provide a powerful probe of galactic mass distributions out to large look-back times. We then use a sample of 13 galaxies, with Spitzer 3.6 μm imaging data and observed Hα rotation curves, to demonstrate how an inferred shear rate coupled with a bulge-disk decomposition model and a Tully-Fisher-derived velocity normalization can be used to place constraints on a galaxy's baryon fraction and dark matter halo profile. Finally, we show that there appears to be a trend (albeit a weak correlation) between spiral arm pitch angle and halo concentration. We discuss implications for the suggested link between supermassive black hole (SMBH) mass and dark halo concentration, using pitch angle as a proxy for SMBH mass.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2015

DWARF GALAXY ANNIHILATION AND DECAY EMISSION PROFILES FOR DARK MATTER EXPERIMENTS

Gamma-ray searches for dark matter annihilation and decay in dwarf galaxies rely on an understanding of the dark matter density profiles of these systems. Conversely, uncertainties in these density profiles propagate into the derived particle physics limits as systematic errors. In this paper we quantify the expected dark matter signal from 20 Milky Way dwarfs using a uniform analysis of the most recent stellar-kinematic data available. Assuming that the observed stellar populations are equilibrium tracers of spherically symmetric gravitational potentials that are dominated by dark matter, we find that current stellar-kinematic data can predict the amplitudes of annihilation signals to within a factor of a few for the ultra-faint dwarfs of greatest interest. On the other hand, the expected signal from several classical dwarfs (with high-quality observations of large numbers of member stars) can be localized to the ∼20% level. These results are important for designing maximally sensitive searches in current and future experiments using space and ground-based instruments.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2015

A BROADBAND RADIO STUDY OF THE AVERAGE PROFILE AND GIANT PULSES FROM PSR B1821-24A

We present the results of a wideband (720–2400 MHz) study of PSR B1821–24A (J1824–2452A, M28A), an energetic millisecond pulsar (MSP) visible in radio, X-rays and γ-rays. In radio, the pulsar has a complex average profile that spans ≳85% of the spin period and exhibits strong evolution with observing frequency. For the first time we measure phase-resolved polarization properties and spectral indices of radio emission throughout almost all of the on-pulse window. We synthesize our findings with high-energy information to compare M28A to other known γ-ray MSPs and to speculate that M28A’s radio emission originates in multiple regions within its magnetosphere (i.e., both in the slot or outer gaps near the light cylinder and at lower altitudes above the polar cap). M28A is one of a handful of pulsars that are known to emit giant radio pulses (GRPs)—short, bright radio pulses of unknown nature. We report a drop in the linear polarization of the average profile in both windows of GRP generation and also a “W”-shaped absorption feature (resembling a double notch), partly overlapping with one of the GRP windows. The GRPs themselves have broadband spectra consisting of multiple patches with Δν/ν ∼ 0.07. Although our time resolution was not sufficient to resolve the GRP structure on the μs scale, we argue that GRPs from this pulsar most closely resemble the GRPs from the main pulse of the Crab pulsar, which consist of a series of narrowband nanoshots.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2015

A new dynamical mass measurement for the Virgo cluster using the radial velocity profile of the filament galaxies

The radial velocities of the galaxies in the vicinity of a cluster show deviation from the pure Hubble flow due to their gravitational interaction with the cluster. According to a recent study by Falco et al. based on a high-resolution N-body simulation, the radial velocity profile of galaxies located at distances larger than three times the virial radius of a neighboring cluster can be well approximated by a universal formula, and could be reconstructed from direct observables provided that the galaxies are distributed along a one-dimensional filament. They suggested an algorithm designed to estimate the dynamic mass of a cluster M{sub v} by fitting the universal formula from the simulation to the reconstructed radial velocity profile of the filament galaxies around the cluster from observations. We apply the algorithm to two narrow, straight filaments (referred to as Filaments A and B) that were recently identified by Kim et al. in the vicinity of the Virgo cluster from the NASA-Sloan-Atlas catalog. The dynamical mass of the Virgo cluster is estimated to be M{sub v}=(0.84{sub −0.51}{sup +2.75})×10{sup 15} h{sup −1} M{sub ⊙} and M{sub v}=(3.24{sub −1.31}{sup +4.99})×10{sup 15} h{sup −1} M{sub ⊙} for the cases of Filaments A and B, respectively. We discuss the observational and theoretical systematics intrinsic to the method of Falco et al. as well as the physical implication of the final results.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2018

Ion acceleration in electrostatic collisionless shock: on the optimal density profile for quasi-monoenergetic beams

Here, a numerical study on ion acceleration in electrostatic shock waves is presented, with the aim of determining the best plasma configuration to achieve quasi-monoenergetic ion beams in laser-driven systems. It was recently shown that tailored near-critical density plasmas characterized by a long-scale decreasing rear density profile lead to beams with low energy spread (Fiúza et al 2012 Phys. Rev. Lett. 109 215001). In this work, a detailed parameter scan investigating different plasma scale lengths is carried out. As result, the optimal plasma spatial scale length that allows for minimizing the energy spread while ensuring a significant reflection of ions by the shock is identified. Furthermore, a new configuration where the required profile has been obtained by coupling micro layers of different densities is proposed. Lastly, results show that this new engineered approach is a valid alternative, guaranteeing a low energy spread with a higher level of controllability.

43 PARTICLE ACCELERATORS↗
DOE OSTI2020

Spectral treatment of gyrokinetic profile curvature

Using a novel wavenumber-advection algorithm, we show that profile curvature (shear in the profile gradient) can be implemented with spectral accuracy in gyrokinetic turbulence simulations. Here, this approach enables a global simulation capability with the relatively low cost and high accuracy of local simulations. Using this new algorithm, we show that for a well-studied tokamak core test case, the effect of temperature-gradient curvature is below the threshold of detectability for experimentally-relevant values of curvature.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2020

Development of a tomographic reconstruction method for axisymmetric D α emission profiles in the ITER plasma boundary

A tomographic method for reconstructing the axially symmetric D α emission profile in the ITER scrape-off layer and divertor from D α intensity measurements in the fields of view (FoV) of Vis/IR TV and Divertor Impurity Monitor diagnostics is under development. The method takes into account the strong background signal due to stray light from divertor produced by reflections from the metal wall of the vacuum chamber. The method allows to filter out the reflections in D α signals measured in the main chamber. Here, the accuracy of this method is tested within the framework of a synthetic diagnostic, which uses the Raysect and Cherab numerical codes for ray-tracing simulations. The D α emission profiles, simulated with the SOLPS and OEDGE codes, are used as synthetic experimental data. Uncertainty in light reflection properties of the first wall (FW) is the major factor affecting the accuracy of the D α emission reconstruction. The dependence on the uncertainty in the FW surface roughness and on the ratio of diffusive to specular reflection of the error in recovering useful D α signals (the direct light without reflections) in the FoV of the ITER main chamber H-alpha and Visible Spectroscopy Diagnostic is obtained.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2024

Investigation of core transport changes in DIII-D discharges with off-axis T e profile peaks

Abstract DIII-D discharges that transition to H-mode solely with off-axis electron cyclotron heating (ECH) often exhibit strong off-axis peaking of electron temperature profiles at the heating location. Electron heat transport properties near these off-axis temperature peaks have been studied using modulated ECH. The Fourier analyzed electron temperature data have been used to infer electron thermal diffusivity. Comparisons with numerical solutions of the time-dependent electron thermal equation find that the data are consistent with a narrow region with electron diffusivity χ e an order of magnitude lower than the average value across the plasma, suggesting an electron internal transport barrier (ITB) near the ECH heating location. Detailed profile analysis and equilibrium reconstructions suggest that the formation of these ITBs are correlated with off-axis values of the safety factor q being near 1. Furthermore, the ECH driven H-mode discharges demonstrate more rapid electron heating rate near the ECH deposition location than L-mode discharges with higher auxiliary ECH heating power. Additional modeling attributes this difference to the modification of electron heat transport in the core at the L-H transition, which also sustains the off-axis electron temperature peaks.

Physics↗