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DOE OSTI2022

SULI Research Report Paper

The Intelligence and Space Research Group 4 (ISR-4) at the Los Alamos National Laboratory focuses on signal processing and developing space electronics for various national security missions. The Space and Atmospheric Burst Reporting System (SABRS) is a sensing payload designed for nuclear detonation detection. As the sensors from previous payloads become obsolete, the requirement for a novel payload design increases. SABRS Prime is the successor to the previous SABRS payloads and is scheduled for delivery in 2028. As part of the SABRS Prompt Gamma Instrument Interface Board, high frequency signals from silicon photomultiplier tubes need to be split and subsequently transmitted to the Analog to Digital Converter. Prior to developing the Space Grade Instrument Interface Board, evaluation modules with Commercial off-the-shelf (COTS) components are evaluated and tested under rigorous conditions. Verification of power levels and gain specifications are some of the important steps taken during the evaluation stage. Working on the Signal Splitting Board has enabled me to work with various schematic software applications and learn more about the processes behind designing space grade electronic components. In addition, I conducted research on efficiency improvements for space-based power systems. Changes in design approaches were found to be the most significant sources of improvement. Being able to interact with researchers and peers across various scientific disciplines has given me a better insight into my future pursuits. Working in a R&D environment has cemented my decision to work on space applications for Quantum Sensing and pursue a PhD in Electrical Engineering. The SULI internship program at the Los Alamos National Laboratory has helped me develop the skillset of a researcher, understand the rigorous processes behind developing space grade hardware, and improve my critical thinking abilities to support the development of reliable instrumentation for deep space missions.

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEF↗

DOE OSTI2022

Conditional analysis of temperature and strain rate effects on dissipation structure in turbulent non-premixed jet flames

Here, this work presents results from simultaneous high-resolution temperature and velocity measurements in a series of turbulent non-premixed jet flames. The filtered Rayleigh scattering (FRS)-based temperature measurements demonstrate sufficient signal-to-noise (SNR) and spatial resolution to estimate the smallest scalar length scales and accurately determine dissipation rate fields. A comprehensive set of conditional statistics are used to characterize the small-scale structure, including the dependence of dissipation layer widths on Reynolds number, temperature, and dissipation magnitude. In general, the dissipation layer thickness decrease with increasing Reynolds number and increase with increasing temperature. However, dissipation layer widths show two distinct behaviors with respect to dissipation magnitude. For small dissipation values, increases in magnitude results in broadening of the dissipation layer, while for larger magnitude values of dissipation, the layer widths are thinned, highlighting the complexity of small-scale turbulent mixing. Additionally, measured ratios of the dissipation layer width to the Batchelor length scale are consistent across all Reynolds numbers and agree with previous studies in non-reacting flows. The unique aspect about the current set of measurements is the ability to examine the interaction of dissipation structure with turbulent flow parameters for the first time in turbulent non-premixed flames. Particularly, the strain rate/dissipation relationship is examined and compared to previous studies in non-reacting flows. It is found that the dissipation layers tend to align normal to the principal compressive strain axis and this tendency increases with increasing Reynolds number. For the lowest Reynolds number case, no dependence of the dissipation layer width nor dissipation rate magnitude on strain rate is found. However, for higher Reynolds numbers, a strong dependence of the dissipation layer width and dissipation rate magnitude on the principal compressive strain rate is observed. These results indicate the direct role of the compressive strain rate field on small-scale mixing structure in reacting flows.

42 ENGINEERING↗

DOE OSTI2014

Diamond neutral particle spectrometer for fusion reactor ITER

A compact diamond neutral particle spectrometer with digital signal processing has been developed for fast charge-exchange atoms and neutrons measurements at ITER fusion reactor conditions. This spectrometer will play supplementary role for Neutral Particle Analyzer providing 10 ms time and 30 keV energy resolutions for fast particle spectra in non-tritium ITER phase. These data will also be implemented for independent studies of fast ions distribution function evolution in various plasma scenarios with the formation of a single fraction of high-energy ions. In tritium ITER phase the DNPS will measure 14 MeV neutrons spectra. The spectrometer with digital signal processing can operate at peak counting rates reaching a value of 10{sup 6} cps. Diamond neutral particle spectrometer is applicable to future fusion reactors due to its high radiation hardness, fast response and high energy resolution.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

DOE OSTI2013

Evaluating Swallowing Muscles Essential for Hyolaryngeal Elevation by Using Muscle Functional Magnetic Resonance Imaging

Purpose: Reduced hyolaryngeal elevation, a critical event in swallowing, is associated with radiation therapy. Two muscle groups that suspend the hyoid, larynx, and pharynx have been proposed to elevate the hyolaryngeal complex: the suprahyoid and longitudinal pharyngeal muscles. Thought to assist both groups is the thyrohyoid, a muscle intrinsic to the hyolaryngeal complex. Intensity modulated radiation therapy guidelines designed to preserve structures important to swallowing currently exclude the suprahyoid and thyrohyoid muscles. This study used muscle functional magnetic resonance imaging (mfMRI) in normal healthy adults to determine whether both muscle groups are active in swallowing and to test therapeutic exercises thought to be specific to hyolaryngeal elevation. Methods and Materials: mfMRI data were acquired from 11 healthy subjects before and after normal swallowing and after swallowing exercise regimens (the Mendelsohn maneuver and effortful pitch glide). Whole-muscle transverse relaxation time (T2 signal, measured in milliseconds) profiles of 7 test muscles were used to evaluate the physiologic response of each muscle to each condition. Changes in effect size (using the Cohen d measure) of whole-muscle T2 profiles were used to determine which muscles underlie swallowing and swallowing exercises. Results: Post-swallowing effect size changes (where a d value of >0.20 indicates significant activity during swallowing) for the T2 signal profile of the thyrohyoid was a d value of 0.09; a d value of 0.40 for the mylohyoid, 0.80 for the geniohyoid, 0.04 for the anterior digastric, and 0.25 for the posterior digastric-stylohyoid in the suprahyoid muscle group; and d values of 0.47 for the palatopharyngeus and 0.28 for the stylopharyngeus muscles in the longitudinal pharyngeal muscle group. The Mendelsohn maneuver and effortful pitch glide swallowing exercises showed significant effect size changes for all muscles tested, except for the thyrohyoid. Conclusions: Muscles of both the suprahyoid and the longitudinal pharyngeal muscle groups are active in swallowing, and both swallowing exercises effectively target muscles elevating the hyolaryngeal complex. mfMRI is useful in testing swallowing muscle function.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

DOE OSTI2018

Sensitivity of Seismically Cued Antineutrino Detectors to Nuclear Explosions

Here, we evaluate the sensitivity of large gadolinium-doped water detectors to antineutrinos released by nuclear-fission explosions, using updated signal and background models and taking advantage of the capacity for seismic observations to provide an analysis trigger. Under certain realistic conditions, the antineutrino signature of a 250-kton pure-fission explosion could be identified several hundred kilometers away, in a detector about the size of the largest module currently proposed for a basic physics experiment. In principle, such an observation could provide rapid confirmation that the seismic signal coincided with a fission event, possibly useful for international monitoring of nuclear-weapon tests. We discuss the limited potential for seismically cued antineutrino observations to constrain fission yield, differentiate pure fission from fusion-enhanced weapon tests, indicate that the seismic evidence of an explosion had been intentionally masked, or verify the absence of explosive testing in a targeted area. We conclude that advances in seismic monitoring and neutrino physics have made the detection of explosion-derived antineutrinos more conceivable than previously asserted, but the size and cost of sufficiently sensitive detectors continue to limit applications.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

DOE OSTI2016

3-cm fine structure masers: A unique signature of supermassive black hole formation via direct collapse in the early universe

The direct collapse black hole (DCBH) scenario describes the isothermal collapse of a pristine gas cloud directly into a massive, M{sub BH} = 10{sup 4}–10{sup 6}M{sub ⊙} black hole. In this paper we show that large H i column densities of primordial gas at T∼10{sup 4} K with low molecular abundance—which represent key aspects of the DCBH scenario—provide optimal conditions for the pumping of the 2p-level of atomic hydrogen by trapped Lyα photons. This Lyα pumping mechanism gives rise to an inverted level population of the 2s{sub 1/2}−2p{sub 3/2} transition, and therefore also gives rise to stimulated fine structure emission at λ=3.04 cm (rest-frame). We show that simplified models of the DCBH scenario amplify the CMB by up to a factor of ∼10{sup 5}, above which the maser saturates. Hyperfine splitting of the 3 cm transition gives rise to a characteristic broad (FWHM ∼ tens of MHz in the observers frame) asymmetric line profile. This signal subtends an angular scale of ∼1–10 mas, which translates to a flux of ∼0.3–3 μJy, which is detectable with ultra-deep surveys being planned with SKA1-MID. While challenging, as the signal is visible for a fraction of the collapse time of the cloud, the matching required physical conditions imply that a detection of the redshifted 3-cm emission line could provide direct evidence for the DCBH scenario.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2018

Digital pulse deconvolution with adaptive shaping for real-time high-resolution high-throughput gamma spectroscopy

A high-resolution high-throughput real-time adaptive digital pulse processing system is developed for high count rate gamma-ray spectroscopy applications. The adaptive digital pulse processing algorithms are implemented on a reconfigurable FPGA and include a pulse deconvolver, adaptive shaping filter, timing filter, baseline restorer, and pile-up rejecter. Digital pulse deconvolution is implemented to reconstruct the original detector signal from the preamplifier signal, which reduces the resolution deterioration due to pulse pile-up. The deconvoluted signal is shaped with a trapezoid filter and the shaping parameter is selected adaptively based on the time separation between successive input pulses. Experimental measurements are performed with a 137Cs source under varying count-rate conditions and using germanium detectors equipped with resistive feedback and transistor reset preamplifiers (TRP). The results herein demonstrate that when using a TRP, adaptive digital signal processing allows handling 106 counts/s. In addition, the implementation of a deconvolution approach limits resolution deterioration for throughput rates that are 4 to 10 times better than achievable in typical digital and analog gamma-ray spectroscopy systems.

47 OTHER INSTRUMENTATION↗

NASA NTRS1997

The Accuracy of Saccadic and Perceptual Decisions in Visual Search

Saccadic eye movements during search for a target embedded in noise are suboptimally guided by information about target location. Our goal is to compare the spatial information used to guide the saccades with that used for the perceptual decision. Three observers were asked to determine the location of a bright disk (diameter = 21 min) in white noise (signal-to-noise ratio = 4.2) from among 10 possible locations evenly spaced at 5.9 deg eccentricity. In the first of four conditions, observers used natural eye movements. In the three remaining conditions, observers fixated a central cross at all times. The fixation conditions consisted of three different presentation times (100, 200, 300 msec), each followed by a mask. Eye-position data were collected, with a resolution of (approximately) 0.2 deg. In the natural viewing condition, we measured. the accuracy with respect to the target and the latency of the first saccade. In the fixation conditions, we discarded trials in which observers broke fixation. Perceptual performance was computed for all conditions. Averaged across observers, the first saccade was correct (closest to the target location) for 56 +/- (SD) % of trials (chance = 10 %) and occurred after a latency of 313 +/- 56 msec. Perceptual performance averaged 53 +/- 4, 63 +/- 4, 65 +/- 2 % correct at 100, 200, and 300 msec, respectively. For the signal-to-noise ratio used, at the time of initiation of the first saccade, there is little difference between the amount of information about target location available to the perceptual and saccadic systems.

Eckstein, Miguel P.↗

DOE OSTI2023

Solar, Atmospheric, and Volcanic Impacts on 10 Be Depositions in Greenland and Antarctica During the Last 100 Years

Cosmogenic radionuclides (e.g., 10 Be) from ice cores are a powerful tool for solar reconstructions back in time. However, superimposed on the solar signal, other factors like weather/climate and volcanic influences on 10 Be can complicate the interpretation of 10 Be data. A comprehensive study of 10 Be records over the recent period, when atmospheric 10 Be production and meteorological conditions are relatively well-known, can improve our interpretation of 10 Be records. Here we conduct a systematic study of the production and climate/volcanic signals in Antarctica and Greenland 10 Be records, including a new 10 Be record from the East GReenland Ice-core Project site. Greenland and Antarctica records show significant decreasing trends (5%–6.5%/decade) for 1900–1950, which is comparable with the expected production rate inferred from sunspot observations. By comparing 10 Be records with reanalysis data and atmospheric circulation patterns, 10 Be records from Southern/Southeastern Greenland are significantly correlated with the Scandinavia pattern. Stacking 10 Be records from different locations can enhance the production signal. However, this approach is not always straightforward as uncertainties in some records can lead to a weaker solar signal. A strategy can be employed to select records for the bipolar stack by comparing Greenland records with Antarctica records, assuming the shared signal is a production signal. Finally, we observe significant increases (36%–64%) in 10 Be depositions in Greenland related to the Agung eruption. This large increase in Greenland 10 Be records after the Agung eruption, could be partly explained by the enhanced air mass transport from mid-latitudes coinciding with the decreased precipitation en-route.

10Be↗

NASA NTRS1982

Propagation of wide bandwidth signals through strongly turbulent ionized media

Analytic and numerical techniques are presented which directly address the problem of propagation of wide bandwidth signals through random ionized media. This work is applicable to the problems of satellite communication and space based radar observation through a disturbed ionospheric propagation channel that would result from a high altitude chemical release or nuclear detonation. An analytic solution is presented for the two-position, two-frequency mutual coherence function for spherical wave propagation in the strong scattering limit. This solution is used to derive simple expressions for the power impulse response function and to determine its relationship to the important parameters of decorrelation distance and coherence bandwidth which describe the disturbed propagation channel. Results for mean time delay and time delay jitter are presented and compared to direct simulation results and to other theoretical calculations. A numerical/analytical solution to the parabolic wave equation is presented in the form of a multiple phase-screen (MPS) propagation simulation. In this very general solution technique, the random medium is divided into a finite number of layers. The field fluctuation through each layer is obtained by replacing the layer by a centrally located thin phase-screen, whose statistical properties are determined from the statistics of the electron-density irregularities. The waveform then propagates from phase-screen to phase-screen via an exact solution to the Fresnel-Kirchnoff equation. For wide bandwidth waveforms, numerical solutions are obtained at a number of discrete frequencies centered about the carrier and then time-domain solutions are obtained by Fourier transform techniques. Detailed results are presented for a number of interesting cases including propagation of a 20 MHz bandwidth signal through a finite barium cloud at a carrier frequency of 100 MHz. One of the major uses of the MPS propagation simulation has been to provide realizations of the received signal after propagation through a disturbed channel. The MPS simulation obtains a general solution of the parabolic wave equation under both weak and strong scattering conditions. A second technique to directly obtain realizations of wide bandwidth waveforms is presented here. This technique is limited to the case of strong scattering but requires only a fraction of the computer resources needed for MPS signal generation. Detailed comparisons of the two signal generation techniques are presented.

Random Media↗

DOE OSTI2025

Enabling Grid-Forming Control Under Unbalanced Conditions

Standalone microgrids often experience unbalanced loading and faults, which can cause grid-forming control designed for balanced conditions to produce oscillatory responses. To address this issue, a compact time-domain transformation appropriate for inverter control is proposed, allowing the conversion of unbalanced three-phase signals to positive and negative synchronous reference frames. This transformation supports the development of a grid-forming control with fault ride-through, featuring frequency and voltage droop controllers and nested current and voltage control loops that seamlessly integrate an enhanced current limiter. The effectiveness of the proposed control and transformation is demonstrated through analytical results and electromagnetic transient simulation.

24 - POWER TRANSMISSION AND DISTRIBUTION↗

NASA NTRS2023

Ventilation Heat Exchanger / Flow Meter for xPLSS

The flow meter / heat exchanger (FMHX) in the ventilation loop of the exploration EMU cools the ventilation gas and measures the ventilation flow rate. The heat exchanger transfers heat from the ventilation gas to the thermal control loop via a miniature shell-and-tube heat exchanger. The flow meters calculate the flow rate of gas through the ventilation loop based on the pressure drop across the heat exchanger core. Creare has delivered four design validation test (DVT) heat exchangers and five DVT flow meters to NASA JSC to support development of the exploration portable life support system (xPLSS). This paper describes the design and performance of the DVT units.The heat exchangers are designed to cool the ventilation gas to a specified temperature with low pressure losses under the most challenging operating conditions. The measured performance of the DVT heat exchangers agrees well with design models and meets all performance requirements. The flow meters use a MEMS thermal flow sensor to produce a signal that is proportional to a small bypass flow around the heat exchanger core. They are designed to achieve high measurement accuracy across the full range of xPLSS operating conditions. We calibrated the flow meters in a special-purpose flow facility that simulates operation in the xPLSS ventilation loop. Calibration testing shows that DVT flow meters produce digital output for vent loop mass flow that meets NASA’s accuracy requirements across the range of xPLSS operating conditions. This paper reviews the design of the heat exchangers and flow meters and presents data from the final flow meter calibration testing, heat exchanger performance validation, and initial ground testing in NASA’s xPLSS.

spacesuit↗

NASA NTRS2023

Ventilation Heat Exchanger / Flow Meter for xPLSS

spacesuit↗

DOE OSTI2017

Copper Sensing in Alkaline Electrolyte Using Anodic Stripping Voltammetry by Means of a Lead Mediator

Anodic stripping voltammetry (ASV) is an analysis technique that permits the selective and quantitative analysis of metal ion species in solution. It is most commonly applied in neutral to acidic electrolyte largely due to inherent metal ion solubility. Bismuth (Bi) is a common film used for ASV due to its good sensitivity, overall stability and insensitivity to O2. ASV, utilizing a Bi film, along with cadmium (Cd) and lead (Pb) as the plating mediators, has recently been adapted to determine zinc (Zn) concentrations in highly alkaline environments (30 % NaOH or 35 % M KOH). Successful analysis of Zn in alkaline relies on the ability of the hydroxide to form soluble metal anion species, such as Bi(OH) 4 – and Zn(OH) 4 2– . Here, we look to extend this technique to detect and quantify copper (Cu) ions in these highly basic electrolytes. However, in general, the use of ASV to detect and quantify Cu ion concentrations is notoriously difficult as the Cu stripping peak potential overlays with that of Bi from the common Bi film electrode. Here, an ASV method for determining Cu concentration in alkaline solutions is developed utilizing Pb as a deposition mediator. As such, it was found that when analyzing Cu solutions in the presence of Pb, the stripping voltammetry curves present separate and defined Cu stripping peaks. Different analyzes were made to find the best stripping voltammetry performance conditions. As such, an accumulation time of 5 minutes, an accumulation potential of ≤–1.45 V vs. Hg/HgO, and a concentration of 35 wt% KOH were determined to be the conditions that presented the best ASV results. Utilizing these conditions, calibration curves in the presence of 5.0 ppm Pb showed the best linear stripping signal correlation with an r-squared value of 0.991 and a limit of detection (LOD) of 0.67 ppm. Lastly, these results give way to evaluating Cu concentrations using ASV in aqueous alkaline solutions.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2022

The effects of advanced spectral line shapes on atmospheric carbon dioxide retrievals

Line shape effects such as speed-dependence and collisional (Dicke) narrowing are manifest in high signal-to-noise ratio laboratory spectra for a wide range of molecular species and sample conditions. However, these effects are usually neglected in spectroscopic models used in remote sensing of atmospheric greenhouse gases. Here, in this study, we examine the effects of line profile choice on laboratory spectra and XCO 2 values retrieved from Total Carbon Column Observing Network (TCCON) spectra. To this end, we utilize limiting cases of the Hartmann-Tran profile (HTP) with shape parameters recently measured by cavity ring-down spectroscopy. Significant differences highlighting the importance of including speed-dependence effects in forward models were observed both in scaling retrievals as well as profile retrievals. However, because of uncertainties associated with the atmospheric temperature gradient, it was not possible to extract accurate carbon column profiles even with inclusion of these new line shape parameters and advanced line profiles.

54 ENVIRONMENTAL SCIENCES↗

DOE OSTI2015

Reactive oxygen species mediate nitric oxide production through ERK/JNK MAPK signaling in HAPI microglia after PFOS exposure

Perfluorooctane sulfonate (PFOS), an emerging persistent contaminant that is commonly encountered during daily life, has been shown to exert toxic effects on the central nervous system (CNS). However, the molecular mechanisms underlying the neurotoxicity of PFOS remain largely unknown. It has been widely acknowledged that the inflammatory mediators released by hyper-activated microglia play vital roles in the pathogenesis of various neurological diseases. In the present study, we examined the impact of PFOS exposure on microglial activation and the release of proinflammatory mediators, including nitric oxide (NO) and reactive oxidative species (ROS). We found that PFOS exposure led to concentration-dependent NO and ROS production by rat HAPI microglia. We also discovered that there was rapid activation of the ERK/JNK MAPK signaling pathway in the HAPI microglia following PFOS treatment. Moreover, the PFOS-induced iNOS expression and NO production were attenuated after the inhibition of ERK or JNK MAPK by their corresponding inhibitors, PD98059 and SP600125. Interestingly, NAC, a ROS inhibitor, blocked iNOS expression, NO production, and activation of ERK and JNK MAPKs, which suggested that PFOS-mediated microglial NO production occurs via a ROS/ERK/JNK MAPK signaling pathway. Finally, by exposing SH-SY5Y cells to PFOS-treated microglia-conditioned medium, we demonstrated that NO was responsible for PFOS-mediated neuronal apoptosis. - Highlights: • PFOS exposure induced expression of iNOS and production of NO in HAPI microglia. • PFOS induced the production of ROS in HAPI microglia. • ERK/JNK MAPK pathways were activated following PFOS exposure in HAPI microglia. • NO released by HAPI microglia participated in the apoptosis of SH-SY5Y cells.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2019

Functional Diversification of ER Stress Responses in Arabidopsis

The endoplasmic reticulum (ER) is responsible for the synthesis of one-third of the cellular proteome and is constantly challenged by physiological and environmental situations that can perturb its homeostasis and lead to the accumulation of misfolded secretory proteins, a condition referred to as ER stress. In response, the ER evokes a set of intracellular signaling processes, collectively known as the unfolded protein response (UPR), which are designed to restore biosynthetic capacity of the ER. As single-cell organisms evolved into multicellular life, the UPR complexity has increased to suit their growth and development. In this review, we discuss recent advances in the understanding of the UPR, emphasizing conserved UPR elements between plants and metazoans and highlighting unique plant-specific features.

59 BASIC BIOLOGICAL SCIENCES↗

DOE OSTI2019

Exploiting the Semidestructive Nature of Gas Cluster Ion Beam Time-of-Flight Secondary Ion Mass Spectrometry Imaging for Simultaneous Localization and Confident Lipid Annotations

Lipids have been considered as key players in cell signaling and disease. Information on their location and distribution within a biological system, under varying conditions, is necessary to understand the contributions of different lipid species to an altered phenotype. Imaging mass spectrometry techniques, such as time-of-flight secondary ion mass spectrometry (ToF-SIMS) and matrix-assisted laser desorption/ionization (MALDI), are capable of revealing global lipid distributions in tissues in an untargeted fashion. Yet, to confidently identify the species present in a sample, orthogonal analyses like tandem MS (MS/MS) are often required. This can be accomplished by bulk sample analysis with liquid chromatography (LC)-MS/MS, which can provide confident lipid identifications, at the expense of losing location-specific information. Here, using planarian flatworms as a model system, we demonstrate that imaging gas cluster ion beam (GCIB)-ToF-SIMS has the unique capability to simultaneously detect, identify, and image lipid species with subcellular resolution in tissue sections. The parallel detection of both, intact lipids and their respective fragments, allows for unique identification of some species without the need of performing an additional orthogonal MS/MS analysis. This was accomplished by correlating intact lipid and associated fragment SIMS images. The lipid assignments, respective fragment identities, and locations gathered from ToF-SIMS data were confirmed via LC-MS/MS on lipid extracts and ultrahigh mass resolution MALDI-MS imaging. Together, these data show that the semidestructive nature of ToF-SIMS can be utilized advantageously to enable both confident molecular annotations and to determine the locations of species within a biological sample.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗