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At least 1,603 records · Page 89

Experimental Studies of Single Invariant Quasi-Integrable Nonlinear Optics at IOTA

The Integrable Optics Test Accelerator is a research electron and proton storage ring recently commissioned at the Fermilab Accelerator Science and Technology facility. Its research program is focused on testing novel techniques for improving beam stability and quality, notably the concept of non-linear integrable optics. In this paper, we report on run 1 results of experimental studies of a quasi-integrable transverse focusing system with one invariant of motion, a Henon-Heiles type system implemented with octupole magnets. Good agreement with simulations is demonstrated on key parameters of achievable tune spread, dynamic aperture, and invariant conservation. We also outline current simulation and hardware improvement efforts for run 2, planned for fall of 2019.

43 PARTICLE ACCELERATORS↗

Online Modelling and Optimization of Nonlinear Integrable Systems

Nonlinear integrable optics was recently proposed as a design approach to increase the limits on beam brightness and intensity imposed by fast collective instabilities. To study these systems experimentally, a new research electron and proton storage ring, the Integrable Optics Test Accelerator, was constructed and recently commissioned at Fermilab. Beam-based diagnostics and online modelling of nonlinear systems presents unique challenges - in this paper, we report on our efforts to develop optimization methods suited for such lattices. We explore the effectiveness of neural networks as fast online surrogate estimators, and integrate them into a beam-based tuning algorithm. We also develop a method of knob dimensionality reduction and subsequent robust multivariate optimization for maximizing key performance metrics under complicated lattice optics constraints.

43 PARTICLE ACCELERATORS↗

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals

The microenvironment of cells controls their phenotype, and thereby the architecture of the emerging multicellular structure or tissue. We have reported more than a dozen microenvironmental factors whose signaling must be integrated in order to effect an organized, functional tissue morphology. However, the factors that prevent integration of signaling pathways that merge form and function are still largely unknown. We have identified nuclear factor kappa B (NFkB) as a transcriptional regulator that disrupts important microenvironmental cues necessary for tissue organization. We compared the gene expression of organized and disorganized epithelial cells of the HMT-3522 breast cancer progression series: the non-malignant S1 cells that form polarized spheres (‘acini’), the malignant T4-2 cells that form large tumor-like clusters, and the ‘phenotypically reverted’ T4-2 cells that polarize as a result of correction of the microenvironmental signaling. We identified 180 genes that display an increased expression in disorganized compared to polarized structures. Network, GSEA and transcription factor binding site analyses suggested that NFkB is a common activator for the 180 genes. NFkB was found to be activated in disorganized breast cancer cells, and inhibition of microenvironmental signaling via EGFR, beta1 integrin, MMPs, or their downstream signals suppressed its activation. The postulated role of NFkB was experimentally verified: Blocking the NFkB pathway with a specific chemical inhibitor or shRNA induced polarization and inhibited invasion of breast cancer cells in 3D cultures. These results may explain why NFkB holds promise as a target for therapeutic intervention: Its inhibition can reverse the oncogenic signaling involved in breast cancer progression and integrate the essential microenvironmental control of tissue architecture.

59 BASIC BIOLOGICAL SCIENCES↗

The BayREN Integrated Commercial Retrofits (BRICR) Project: An Introduction and Preliminary Results

BayREN Integrated Commercial Retrofits (BRICR) is a DOE-funded project which aims to enhance the capacity of energy efficiency programs to recruit participants, develop retrofits, and measure outcomes in small and medium-sized commercial buildings, a sector notoriously hard to reach and expensive to serve, that accounts for 2/3 of US commercial floor space. To address these barriers, BRICR leverages existing incentives, financing, data, and open source software to facilitate two paths for comprehensive improvements: a deep energy retrofit, or serial upgrades integrated into capital improvement and maintenance cycles. BRICR is developing an integrated workflow for iterative energy modeling of commercial buildings for city energy program managers and auditors - starting with mass building-scale simulation based on public records and proceeding through audit, retrofit, and measurement and verification stages. BRICR builds on existing tools including LBNL’s CBES, NREL’s OpenStudio, PNNL’s Audit Template, and DOE’s BuildingSync and SEED PlatformTM. At each stage, BRICR uses available information to inform simulations (starting with public records but iteratively augmented with observations from energy program staff) to improve the quality of the models that inform decision making. This paper presents initial results from energy models of 1699 office and retail buildings in San Francisco. Building stock data from public records were translated to create a BuildingSync file for each building which was stored in SEED. Each BuildingSync file was then translated to multiple OpenStudio Workflow files for EnergyPlus simulation to estimate energy savings of energy conservation measures (ECM). Energy savings predictions for each ECM were written back to an updated BuildingSync file for each building and re-uploaded to SEED. The distribution of baseline energy simulations was calibrated against the publicly disclosed distribution of energy benchmarking data to increase confidence in results.

Piette, M↗

Four lectures on Euler integrals

These lecture notes provide a self-contained introduction to Euler integrals, which are frequently encountered in applications. In particle physics, they arise as Feynman integrals or string amplitudes. Our four selected topics demonstrate the diverse mathematical techniques involved in the study of Euler integrals, including polyhedral geometry, very affine varieties, differential equations, and computational algebra.

Matsubara-Heo, Saiei-Jaeyeong↗

Fully integrated safeguards and security for reprocessing plant monitoring.

Nuclear fuel reprocessing plants contain a wealth of plant monitoring data including material measurements, process monitoring, administrative procedures, and physical protection elements. Future facilities are moving in the direction of highly-integrated plant monitoring systems that make efficient use of the plant data to improve monitoring and reduce costs. The Separations and Safeguards Performance Model (SSPM) is an analysis tool that is used for modeling advanced monitoring systems and to determine system response under diversion scenarios. This report both describes the architecture for such a future monitoring system and present results under various diversion scenarios. Improvements made in the past year include the development of statistical tests for detecting material loss, the integration of material balance alarms to improve physical protection, and the integration of administrative procedures. The SSPM has been used to demonstrate how advanced instrumentation (as developed in the Material Protection, Accounting, and Control Technologies campaign) can benefit the overall safeguards system as well as how all instrumentation is tied into the physical protection system. This concept has the potential to greatly improve the probability of detection for both abrupt and protracted diversion of nuclear material.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

On Quantum Integrable Systems

Many quantum integrable systems are obtained using an accelerator physics technique known as Ermakov (or normalized variables) transformation. This technique was used to create classical nonlinear integrable lattices for accelerators and nonlinear integrable plasma traps. Now, all classical results are carried over to a nonrelativistic quantum case. In this paper we have described an extension of the Ermakov-like transformation to the Schroedinger and Pauli equations. It is shown that these newly found transformations create a vast variety of time dependent quantum equations that can be solved in analytic functions, or, at least, can be reduced to time-independent ones.

43 PARTICLE ACCELERATORS↗

Geometric integration of the Vlasov-Maxwell system with a variational particle-in-cell scheme

A fully variational, unstructured, electromagnetic particle-in-cell integrator is developed for integration of the Vlasov-Maxwell equations. Using the formalism of Discrete Exterior Calculus, the field solver, interpolation scheme and particle advance algorithm are derived through minimization of a single discrete field theory action. As a consequence of ensuring that the action is invariant under discrete electromagnetic gauge transformations, the integrator exactly conserves Gauss's law.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Upstream Measurements of Wind Profiles with Doppler Lidar for Improved Wind Energy Integration

New upstream measurements of wind profiles over the altitude range of wind turbines will be produced using a scanning Doppler lidar. These long range high quality measurements will provide improved wind power forecasts for wind energy integration into the power grid. The main goal of the project is to develop the optimal Doppler lidar operating parameters and data processing algorithms for improved wind energy integration by enhancing the wind power forecasts in the 30 to 60 minute time frame, especially for the large wind power ramps. Currently, there is very little upstream data at large wind farms, especially accurate wind profiles over the full height of the turbine blades. The potential of scanning Doppler lidar will be determined by rigorous computer modeling and evaluation of actual Doppler lidar data from the WindTracer system produced by Lockheed Martin Coherent Technologies, Inc. of Louisville, Colorado. Various data products will be investigated for input into numerical weather prediction models and statistically based nowcasting algorithms. Successful implementation of the proposed research will provide the required information for a full cost benefit analysis of the improved forecasts of wind power for energy integration as well as the added benefit of high quality wind and turbulence information for optimal control of the wind turbines at large wind farms.

17 WIND ENERGY↗

Verification of J-integral capability in Sierra Mechanics

A finite-deformation, massively parallel, domain J -integral has been developed in Sierra Me- chanics with specific emphasis on pressurized loadings. We review the development of the domain integral and the inclusion of terms to correct for boundary tractions. We note the syntax employed in Sierra and illustrate the choice of weight function. Details are provided regarding domain selection, erack direction, and the construction of the test function. Be- cause quality meshes are required to obtain accurate measures of the driving force, methods were developed in Cubit for creating element boundaries orthogonal to the crack front. We briefly review the new capabilities and provide guidance for mesh construction. A compre- hensive set of examples illustrate the current implementation in Sierra. Examples include straight crack fronts, curved crack fronts, and non-planar crack faces. We investigate elastic and elastic-plastic cases. The inclusion of boundary tractions is verified through a pressur- ized ellipsoidal flaw. When possible, the calculated driving forees are compared to analytical solutions. Although the J -integral is available in many commercial codes, the finite defor- mation implementation in Sierra will enable analysts to examine detailed component level models and include fracture mechanics as a tool in the Sandia design process.

Ohashi, Yuki↗

Integrated Building Management System (IBMS)

This project provides a combination of software and services that more easily and cost-effectively help to achieve optimized building performance and energy efficiency. Featuring an open-platform, cloud- hosted application suite and an intuitive user experience, this solution simplifies a traditionally very complex process by collecting data from disparate building systems and creating a single, integrated view of building and system performance. The Fault Detection and Diagnostics algorithms developed within the IBMS have been designed and tested as an integrated component of the control algorithms running the equipment being monitored. The algorithms identify the normal control behaviors of the equipment without interfering with the equipment control sequences. The algorithms also work without interfering with any cooperative control sequences operating between different pieces of equipment or building systems. In this manner the FDD algorithms create an integrated building management system.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Integrated Genome-Based Studies of Shewanella Ecophysiology

Integration of bioinformatics and experimental techniques was applied to mapping and characterization of the key components (pathways, enzymes, transporters, regulators) of the core metabolic machinery in Shewanella oneidensis and related species with main focus was on metabolic and regulatory pathways involved in utilization of various carbon and energy sources. Among the main accomplishments reflected in ten joint publications with other participants of Shewanella Federation are: (i) A systems-level reconstruction of carbohydrate utilization pathways in the genus of Shewanella (19 species). This analysis yielded reconstruction of 18 sugar utilization pathways including 10 novel pathway variants and prediction of > 60 novel protein families of enzymes, transporters and regulators involved in these pathways. Selected functional predictions were verified by focused biochemical and genetic experiments. Observed growth phenotypes were consistent with bioinformatic predictions providing strong validation of the technology and (ii) Global genomic reconstruction of transcriptional regulons in 16 Shewanella genomes. The inferred regulatory network includes 82 transcription factors, 8 riboswitches and 6 translational attenuators. Of those, 45 regulons were inferred directly from the genome context analysis, whereas others were propagated from previously characterized regulons in other species. Selected regulatory predictions were experimentally tested. Integration of this analysis with microarray data revealed overall consistency and provided additional layer of interactions between regulons. All the results were captured in the new database RegPrecise, which is a joint development with the LBNL team. A more detailed analysis of the individual subsystems, pathways and regulons in Shewanella spp included bioinfiormatics-based prediction and experimental characterization of: (i) N-Acetylglucosamine catabolic pathway; (ii)Lactate utilization machinery; (iii) Novel NrtR regulator of NAD biosynthesis; (iv) HexR-controlled global regulon in central metabolism. In addition to numerous specific findings contributing to basic understanding of ecophysiology and evolution of Shewanella, the key components of the integrative genomic methodology of general utility for the community were optimized, validated and disseminated.

59 BASIC BIOLOGICAL SCIENCES↗

Integral and Separate Effects Tests for Thermal Hydraulics Code Validation for Liquid-Salt Cooled Nuclear Reactors

The objective of the 3-year project was to collect integral effects test (IET) data to validate the RELAP5-3D code and other thermal hydraulics codes for use in predicting the transient thermal hydraulics response of liquid salt cooled reactor systems, including integral transient response for forced and natural circulation operation. The reference system for the project is a modular, 900-MWth Pebble Bed Advanced High Temperature Reactor (PB-AHTR), a specific type of Fluoride salt-cooled High temperature Reactor (FHR). Two experimental facilities were developed for thermal-hydraulic integral effects tests (IETs) and separate effects tests (SETs). The facilities use simulant fluids for the liquid fluoride salts, with very little distortion to the heat transfer and fluid dynamics behavior. The CIET Test Bay facility was designed, built, and operated. IET data for steady state and transient natural circulation was collected. SET data for convective heat transfer in pebble beds and straight channel geometries was collected. The facility continues to be operational and will be used for future experiments, and for component development. The CIET 2 facility is larger in scope, and its construction and operation has a longer timeline than the duration of this grant. The design for the CIET 2 facility has drawn heavily on the experience and data collected on the CIET Test Bay, and it was completed in parallel with operation of the CIET Test Bay. CIET 2 will demonstrate start-up and shut-down transients and control logic, in addition to LOFC and LOHS transients, and buoyant shut down rod operation during transients. Design of the CIET 2 Facility is complete, and engineering drawings have been submitted to an external vendor for outsourced quality controlled construction. CIET 2 construction and operation continue under another NEUP grant. IET data from both CIET facilities is to be used for validation of system codes used for FHR modeling, such as RELAP5-3D. A set of numerical models were developed in parallel to the experimental work. RELAP5-3D models were developed for the salt-cooled PB-AHTR, and for the simulat fluid CIET natural circulation experimental loop. These models are to be validated by the data collected from CIET. COMSOL finite element models were used to predict the temperature and fluid flow distribution in the annular pebble bed core; they were instrumental for design of SETs, and they can be used for code-to-code comparisons with RELAP5-3D. A number of other small SETs, and numerical models were constructed, as needed, in support of this work. The experiments were designed, constructed and performed to meet CAES quality assurance requirements for test planning, implementation, and documentation; equipment calibration and documentation, procurement document control; training and personnel qualification; analysis/modeling software verification and validation; data acquisition/collection and analysis; and peer review.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Two-Way Integration of WRF and CCSM for Regional Climate Simulations

Under the support of the DOE award DE-SC0004670, we have successfully developed an integrated climate modeling system by nesting Weather Research and Forecasting (WRF) model within the Community Climate System Model (CCSM) and the ensuing new generation Community Earth System Model (CESM). The integrated WRF/CESM system is intended as one method of global climate modeling with regional simulation capabilities. It allows interactive dynamical regional downscaling in the computational flow of present or future global climate simulations. This capability substantially simplifies the process of dynamical downscaling by avoiding massive intermediate model outputs at high frequency that are typically required for offline regional downscaling. The inline coupling also has the advantage of higher temporal resolution for the interaction between regional and global model components. With the aid of the inline coupling, a capability has also been developed to ingest other global climate simulations (by CESM or other models), which otherwise may not have necessary intermediate outputs for regional downscaling, to realize their embedded regional details. It is accomplished by relaxing the global atmospheric state of the integrated model to that of the source simulations with an appropriate time scale. This capability has the potential to open a new venue for ensemble regional climate simulations using a single modeling system. Furthermore, this new modeling system provides an effective modeling framework for the studies of physical and dynamical feedbacks of regional weather phenomena to the large scale circulation. The projected uses of this capability include the research of up-scaling effect of regional weather system, and its use as an alternative physical representation of sub-scale processes in coarser-resolution climate models.

54 ENVIRONMENTAL SCIENCES↗

Technical Report on Preliminary Methodology for Enhancing Risk Monitors with Integrated Equipment Condition Assessment

Small modular reactors (SMRs) generally include reactors with electric output of ~350 MWe or less (this cutoff varies somewhat but is substantially less than full-size plant output of 700 MWe or more). Advanced SMRs (AdvSMRs) refer to a specific class of SMRs and are based on modularization of advanced reactor concepts. AdvSMRs may provide a longer-term alternative to traditional light-water reactors (LWRs) and SMRs based on integral pressurized water reactor concepts currently being considered. Enhancing affordability of AdvSMRs will be critical to ensuring wider deployment. AdvSMRs suffer from loss of economies of scale inherent in small reactors when compared to large (~greater than 600 MWe output) reactors. Some of this loss can be recovered through reduced capital costs through smaller size, fewer components, modular fabrication processes, and the opportunity for modular construction. However, the controllable day-to-day costs of AdvSMRs will be dominated by operation and maintenance (O&M) costs. Technologies that help characterize real-time risk are important for controlling O&M costs. Risk monitors are used in current nuclear power plants to provide a point-in-time estimate of the system risk given the current plant configuration (e.g., equipment availability, operational regime, and environmental conditions). However, current risk monitors are unable to support the capability requirements listed above as they do not take into account plant-specific normal, abnormal, and deteriorating states of active components and systems. This report documents technology developments that are a step towards enhancing risk monitors that, if integrated with supervisory plant control systems, can provide the capability requirements listed and meet the goals of controlling O&M costs. The report describes research results from an initial methodology for enhanced risk monitors by integrating real-time information about equipment condition and POF into risk monitors.

advanced small modular reactor↗

Integrating the human element into the systems engineering process and MBSE methodology

In response to the challenges related to the increasing size and complexity of systems, organizations have recognized the need to integrate human considerations in the beginning stages of systems development. Human Systems Integration (HSI) seeks to accomplish this objective by incorporating human factors within systems engineering (SE) processes and methodologies, which is the focus of this paper. A representative set of HSI methods from multiple sources are organized, analyzed, and mapped to the systems engineering Vee-model. These methods are then consolidated and evaluated against the SE process and Models-Based Systems Engineering (MBSE) methodology to determine where and how they could integrate within systems development activities in the form of specific enhancements. Overall conclusions based on these evaluations are presented and future research areas are proposed.

60 APPLIED LIFE SCIENCES↗

Integrated Distribution Management System for Alabama Principal Investigator

Southern Company Services, under contract with the Department of Energy, along with Alabama Power, Alstom Grid (formerly AREVA T&D) and others moved the work product developed in the first phase of the Integrated Distribution Management System (IDMS) from “Proof of Concept” to true deployment through the activity described in this Final Report. This Project – Integrated Distribution Management Systems in Alabama – advanced earlier developed proof of concept activities into actual implementation and furthermore completed additional requirements to fully realize the benefits of an IDMS. These tasks include development and implementation of a Distribution System based Model that enables data access and enterprise application integration.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Development and Testing of an Integrated Sandia Cooler Thermoelectric Device (SCTD).

This report describes a FY14 effort to develop an integrated Sandia Cooler T hermoelectric D evice (SCTD) . The project included a review of feasible thermoelectric (TE) cooling applications, baseline performance testing of an existing TE device, analysis and design development of an integrated SCTD assembly, and performance measurement and validation of the integrated SCTD prototype.

Johnson, Terry A.↗