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At least 1,603 records · Page 89

SU-E-T-485: Investigation of a Synthetic Diamond Detector for Tomotherapy Dosimetry

Purpose: Tomotherapy treatments are characterized by rotational deliveries of flattening-filter free fields resulting in high-gradient dose distributions. Small volume, rotationally independent detectors are needed for accurate dosimetry. PTWs microDiamond detector, with its small sensitive volume (0.004mm{sup 3}), could potentially be an ideal detector for Tomotherapy. The microDiamond detector was tested against a small volume Exradin A1SL ion chamber for Tomotherapy open-field and IMRT commissioning measurements. Methods: Custom detector holders were fabricated to allow A1SL and microDiamond measurements in the Tomotherapy Cheese phantom and a square solid water phantom. The microDiamond rotational dependence within the Tomotherapy phantom was tested by incrementally rotating the detector in between static-gantry angle Tomotherapy irradiations. Longitudinal Tomotherapy profiles, for all field sizes, were measured with the microDiamond and A1SL detectors at 1.5cm depth in the square phantom, and compared to film. Detector axes were aligned parallel to table motion. Per TG-119 recommendations, both detectors were calibrated to known doses in phantoms and used to measure high-dose points in TG-119 H and N and Prostate plans. The measurements were compared to the treatment planning system and subsequently compared to published TG-119 confidence limits. Results: The microDiamond angular dependence was less than 0.5%. The average difference between the detectors and film-measured longitudinal profile 80–20% penumbras were 0.03+/-0.04mm and 1.36+/-0.22mm for the microDiamond and A1SL, respectively. The average difference between the detector and filmmeasured field sizes were 0.07+/-0.01mm and 0.09+/-0.02mm for the microDiamond and A1SL, respectively. The measured confidence limits were 0.023 and 0.015 for microDiamond and A1SL, respectively. TG-119 reported a confidence limit of 0.034. Conclusion: The microDiamond measured open-field longitudinal Tomotherapy profiles more closely resembled film measurements, compared with the A1Sl chamber. Furthermore, the microDiamond was shown to have low angular dependence and both detectors were able to accurately measure the highdose points in TG-119 H and N and prostate plans. Our institution has research grants with PTW.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

diamond-sampling

This software provides a means for computing only the largest few entries of the product of two matrices, both exactly and approximately (using randomized sampling techniques). The purpose of the code is to demonstrate both the time it takes to solve the problem as well as the accuracy of the approximate approach. It is also meant to serve as a foundation to test the applicability of the sampling technique to related problems in data mining, including maximum inner product search, nearest neighbor search, and maximum cosine similarity.

Ballard, Grey↗

Characterization of a hard X-ray self-seeding diamond crystal orientation

We present a method to accurately control the photon energies for hard X-ray Self-seeding schemes with a single crystal monochromator in transmissive geometry. The energy calibration is performed by measuring which pairs of the machine pitch and yaw angles for different crystallographic planes reflect the X-ray at the same wavelength. The free parameters of an analytical formula for the self-seeding energies are determined by fitting the observed intersections and the normalized derivative with respect to the pitch and yaw angles in the observed intersections. The method requires a hard X-ray spectrometer, but it does not rely on its absolute energy calibration. Instead, identifying the self-seeded energies above the SASE background or the monochromatic notches within the SASE bandwidth is sufficient for the calibration.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Extension Model: Diamond Phenolic EOS

The procedure for performing an equation of state extension is purely based on the simple assertion that one can break the standard equation of state (EOS) into a three component free energy. The three components are made of a cold curve, ion thermal, and electron thermal part. Assuming that the standard products EOS does not contain an electron thermal component, we only need to extract the cold curve and ion component. The following is a description on how I extracted the two components and extended the tables over the full SESAME density and temperature grids while preserving the limited range table.

36 MATERIALS SCIENCE↗

Diamond Pixel Luminosity Telescopes

In this document, Halyo summaries her key contributions to CMS at the LHC and provide an explanation of their importance and her role in each project. At the end Halyo describes her recent research interest that includes GPU/MIC Acceleration of the High Level Trigger (HLT) to Extend the Physics Research at the LHC. A description of her work the recent promising results that she accomplished and the deliverable are also elaborated. These contribution were only possible thanks to DOE support of junior faculty research and their clear goal to promote research and innovations.

43 PARTICLE ACCELERATORS↗

X-Ray Thomson Scattering from Shock-Compressed Diamond Spheres on the OMEGA Laser

X-ray Thomson scattering (XRTS) is an experimental technique that can directly probe the complicated physics of warm and hot dense matter. The Compton-shifted profile of inelastically-scattered x-rays reflects the electron velocity distribution and can measure temperature and density. The ratio of elastically versus inelastically scattered x-rays is related to the number of tightly bound versus free electrons, and thus reflects the ionization state of the sample. Recent experiments highlight uncertainties in the ionization models often used to describe warm dense matter. More experimental validation of these models is needed to understand the onset of ionization in dense plasmas.

42 ENGINEERING↗

DiaMonD: An Integrated Multifaceted Approach to Mathematics at the Interfaces of Data, Models, and Decisions

For many problems in computational science and engineering, the so-called forward problem—solution of the underlying mathematical model to yield output quantities of interest, given input parameters—is difficult enough for frontier complex models, which are often characterized by coupled multiphysics and possibly stochastic behavior over a wide range of length and time scales. However, we face the need to move beyond the forward problem, to address what is often the ultimate goal of CS&E: decision making. This requires us to tackle a spectrum of mathematical problems that subsume, and are thus even more difficult than, the forward problem. First, given experimental data, we wish to estimate unknown parameters characterizing a model of a natural or engineered system by solving an inverse problem. Second, we seek the optimal configuration of the system (or experiments) by solving an optimal design problem. Third, the optimal operation of the system must be determined by solving an optimal control problem. And fourth, we must quantify uncertainties as they propagate through all of the preceding problems, from data to model inference to prediction and finally to optimal design and control. Optimal mathematical methods and algorithms for such end-to-end, data-to-decisions modeling and simulation of complex problems—requiring integrated solution of forward, inverse, optimization, and UQ problems for large, multiphysics, multiscale models—entails challenges of the highest order, while also presenting great opportunities for applied mathematics research. Unfortunately, research on forward, inverse, optimization, and UQ problems has all-too-often progressed in isolation. This has led to mathematical methods that perform well when considering the forward simulation in isolation, but are prohibitive or suboptimal or unstable when combined with other methods within the framework of inversion, optimization, or UQ. The reverse is also true: general-purpose methods developed within the inversion, optimization, and UQ fields often become prohibitive when applied to complex CS&E problems since they do not exploit their structure.

58 GEOSCIENCES↗