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At least 1,585 records · Page 88

Neutrinos from type Ia supernovae: The deflagration-to-detonation transition scenario

It has long been recognized that the neutrinos detected from the next core-collapse supernova in the Galaxy have the potential to reveal important information about the dynamics of the explosion and the nucleosynthesis conditions as well as allowing us to probe the properties of the neutrino itself. The neutrinos emitted from thermonuclear—type Ia—supernovae also possess the same potential, although these supernovae are dimmer neutrino sources. For the first time, we calculate the time, energy, line of sight, and neutrino-flavor-dependent features of the neutrino signal expected from a three-dimensional delayed-detonation explosion simulation, where a deflagration-to-detonation transition triggers the complete disruption of a near-Chandrasekhar mass carbon-oxygen white dwarf. We also calculate the neutrino flavor evolution along eight lines of sight through the simulation as a function of time and energy using an exact three-flavor transformation code. We identify a characteristic spectral peak at ˜10 MeV as a signature of electron captures on copper. This peak is a potentially distinguishing feature of explosion models since it reflects the nucleosynthesis conditions early in the explosion. We simulate the event rates in the Super-K, Hyper-K, JUNO, and DUNE neutrino detectors with the SNOwGLoBES event rate calculation software and also compute the IceCube signal. Hyper-K will be able to detect neutrinos from our model out to a distance of ˜10 kpc. Here, at 1 kpc, JUNO, Super-K, and DUNE would register a few events while IceCube and Hyper-K would register several tens of events.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Automated Parton-Shower Variations in Pythia 8

In the era of precision physics measurements at the LHC, efficient and exhaustive estimations of theoretical uncertainties play an increasingly crucial role. In the context of Monte Carlo (MC) event generators, the estimation of such uncertainties traditionally requires independent MC runs for each variation, for a linear increase in total run time. In this work, we report on an automated evaluation of the dominant (renormalization-scale and nonsingular) perturbative uncertainties in the pythia 8 event generator, with only a modest computational overhead. Each generated event is accompanied by a vector of alternative weights (one for each uncertainty variation), with each set separately preserving the total cross section. Explicit scale-compensating terms can be included, reflecting known coefficients of higher-order splitting terms and reducing the effect of the variations. The formalism also allows for the enhancement of rare partonic splittings, such as g→bb¯ and q→qγ, to obtain weighted samples enriched in these splittings while preserving the correct physical Sudakov factors.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Why is the winner the best?

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multi- center study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), im- age preprocessing (97%), data curation (79%), and post- processing (66%). The “typical” lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

Eisenmann, Matthias↗

Precancer Atlas to Drive Precision Prevention Trials

Cancer development is a complex process driven by inherited and acquired molecular and cellular alterations. Prevention is the holy grail of cancer elimination, but making this a reality will take a fundamental rethinking and deep understanding of premalignant biology. Here, we propose a national concerted effort to create a Precancer Atlas (PCA), integrating multi-omics and immunity – basic tenets of the neoplastic process. The biology of neoplasia caused by germline mutations has led to paradigm-changing precision prevention efforts, including: tumor testing for mismatch repair (MMR) deficiency in Lynch syndrome establishing a new paradigm, combinatorial chemoprevention efficacy in familial adenomatous polyposis (FAP), signal of benefit from imaging-based early detection research in high-germline risk for pancreatic neoplasia, elucidating early ontogeny in BRCA1-mutation carriers leading to an international breast cancer prevention trial, and insights into the intricate germline-somatic-immunity interaction landscape. Emerging genetic and pharmacologic (metformin) disruption of mitochondrial (mt) respiration increased autophagy to prevent cancer in a Li-Fraumeni mouse model (biology reproduced in clinical pilot) and revealed profound influences of subtle changes in mt DNA background variation on obesity, aging, and cancer risk. The elaborate communication between the immune system and neoplasia includes an increasingly complex cellular microenvironment and dynamic interactions between host genetics, environmental factors, and microbes in shaping the immune response. Cancer vaccines are in early murine and clinical precancer studies, building on the recent successes of immunotherapy and HPV vaccine immune prevention. Molecular monitoring in Barrett's esophagus to avoid overdiagnosis/treatment highlights an important PCA theme. Next generation sequencing (NGS) discovered age-related clonal hematopoiesis of indeterminate potential (CHIP). Ultra-deep NGS reports over the past year have redefined the premalignant landscape remarkably identifying tiny clones in the blood of up to 95% of women in their 50s, suggesting that potentially premalignant clones are ubiquitous. Similar data from eyelid skin and peritoneal and uterine lavage fluid provide unprecedented opportunities to dissect the earliest phases of stem/progenitor clonal (and microenvironment) evolution/diversity with new single-cell and liquid biopsy technologies. Cancer mutational signatures reflect exogenous or endogenous processes imprinted over time in precursors. In conclusion, accelerating the prevention of cancer will require a large-scale, longitudinal effort, leveraging diverse disciplines (from genetics, biochemistry, and immunology to mathematics, computational biology, and engineering), initiatives, technologies, and models in developing an integrated multi-omics and immunity PCA – an immense national resource to interrogate, target, and intercept events that drive oncogenesis.

59 BASIC BIOLOGICAL SCIENCES↗

Air Exchange Rate Impact on Activity Equilibrium Factors and Inhalation Fractional Equilibrium Factors for Rn, Xe, Kr, Ar, Ne, and Their Progeny in Vapor Intrusion, Risk, and Dose Models

Exposure to the radioactive noble gasses, especially radon, is of high concern and poses a significant risk to humans in an indoor air environment as the second leading cause of lung cancer in the United States. To evaluate and minimize the risks posed by these gasses, it is important to understand their radiological and physical properties. The EPA’s Radon Vapor Intrusion Screening Level (RVISL) calculator calculates indoor air RVISLs based on target working levels (WLs), target excess lifetime cancer risk (ELCR), and annual dose limits for the actinon (Rn-219), thoron (Rn-220), and radon (Rn-222) decay series. The RVISLs are based on inhalation and submersion in gas cloud exposure routes for residential and commercial settings. The RVISLs are analogous to preliminary remediation goals (PRGs) and dose compliance concentrations (DCCs), where the isotope-specific values are in units of activity concentration (activity per unit volume). If the concentration of a parent isotope of radon or its progeny is found to exceed the RVISL, then further action to ensure cleanup of the contaminant may be necessary. In residential and commercial settings, the RVISLs will vary based on the air exchange rate present. The EPA’s Radionuclide PRG and DCC Calculators also assess the risk/dose from noble gases in the air due to household use of water like showering. In this study, a computational method in MATLAB was developed to determine the impact of the air exchange rate on the activity equilibrium factor (A eq ) and the inhalation fractional equilibrium factor (F eq ). Both factors are values that reflect the equilibrium concentrations of progeny to their parent in the air. These factors have a direct impact on the RVISL, PRG, and DCC calculations of WL, ELCR, and annual dose, respectively. This study builds on a previous report that only focused on actinon, thoron, and radon by revisiting the original A eq and F eq calculation methods, as well as including the values for the Rn-207, Rn-209, Rn-210, Rn-211, Rn-215, Rn-216, Rn-217, Rn-218, Rn-223, Ne-24, Ar-42, Ar-43, Ar-44, Kr-74, Kr-75, Kr-76, Kr-77, Kr-88, Kr-89, Xe-120, Xe-121, Xe-122, Xe-123, Xe-135m, and Xe-138 decay chains, which are not currently available in literature. The EPA’s RVISL calculator will be updated to include the new A eq and F eq values for the actinon, thoron, and radon decay chains, while the rest of the calculators will incorporate all the new A eq and F eq values as appropriate.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗

Measuring the Stress Factors for Photovoltaic (PV) Backsheet Degradation

Back sheet failure has resulted in power loss and large-scale recall of photovoltaic modules, resulting in billions of dollars in lost revenue. The light exposure on the backside of a photovoltaic module comes primarily from reflected light which alters the distribution of natural sunlight. Because of this, modelling the backside exposure and duplicating the exposure is much more difficult than modeling the frontside exposure. This project aims to study how various back sheets and junction box materials degrade under different conditions and to develop Python code to help model and predict degradation. The stress factors for back-sheet degradation must be quantified to extrapolate accelerated stress tests to the field. Test samples were placed in the A3, A4, and A5 conditions, as defined in IEC 62788-7-2, to assess the temperature and humidity dependence of ultraviolet (UV) induced degradation. We are utilizing a custom chamber with exposure from 0.5 UV-suns to 5 UV-suns to understand the dependence of degradation on light intensity. A group of samples put in the A3 condition had glass filters with 50% UV cut-offs of 320 nm, 335 nm, and 360 nm to assess the wavelength dependence of UV degradation. All this data is necessary to assess the impact of non-standard UV light exposure. The material evaluation tests include gloss measurements, attenuated total internal reflectance Fourier transform infrared spectroscopy (ATR-FTIR), UV-visible reflectance/transmittance utilizing a Cary Ci7000 spectrophotometer, and a nano-indenter for surface hardness and modulus measurements. Alongside the experimental work, there is a computational effort using raytracing and Python open-source tools in PVDeg , PVLib, and Bifacial_Radiance. This code will create specific exposure scenarios and enable the evaluation of chamber degradation relative to field degradation. Equation 1 is a strawman equation used to model degradation on the backside of a PV module. We will create simplified code, based on the results of ray-tracing calculations, which uses a view factor approach to provide fast calculations for the most common exposure scenarios.

14 SOLAR ENERGY↗

Analytical Models of Exoplanetary Atmospheres. IV. Improved Two-stream Radiative Transfer for the Treatment of Aerosols

We present a novel generalization of the two-stream method of radiative transfer, which allows for the accurate treatment of radiative transfer in the presence of strong infrared scattering by aerosols. We prove that this generalization involves only a simple modification of the coupling coefficients and transmission functions in the hemispheric two-stream method. This modification originates from allowing the ratio of the first Eddington coefficients to depart from unity. At the heart of the method is the fact that this ratio may be computed once and for all over the entire range of values of the single-scattering albedo and scattering asymmetry factor. We benchmark our improved two-stream method by calculating the fraction of flux reflected by a single atmospheric layer (the reflectivity) and comparing these calculations to those performed using a 32-stream discrete-ordinates method. We further compare our improved two-stream method to the two-stream source function (16 streams) and delta-Eddington methods, demonstrating that it is often more accurate at the order-of-magnitude level. Finally, we illustrate its accuracy using a toy model of the early Martian atmosphere hosting a cloud layer composed of carbon dioxide ice particles. The simplicity of implementation and accuracy of our improved two-stream method renders it suitable for implementation in three-dimensional general circulation models. In other words, our improved two-stream method has the ease of implementation of a standard two-stream method, but the accuracy of a 32-stream method.

79 ASTRONOMY AND ASTROPHYSICS↗

A study of the microstructure and optical properties of thin lead-dielectric cermet films

A transmission electron microscopy study involving direct and replicating techniques is directed to a definition of the microstructure of radio frequency-sputtered, thin lead-dielectric cermet films. Once defined, this microstructure is used to obtain theoretical film refractive indices. The Maxwell Garnett theory provides a basis for the theoretical results. Measurements of film transmission and reflectivity are used to obtain rough experimental values for film refractive indices by the Tekucheva method. More exact values are obtained via ellipsometry. The rough Tekucheva values are used to determine the range over which computer calculations interpreting the ellipsometric results must be made. This technique yields accurate values for the film refractive indices.

Owen, R. B.↗

Fundamental analysis of the failure of polymer-based fiber reinforced composites

A mathematical model predicting the strength of unidirectional fiber reinforced composites containing known flaws and with linear elastic-brittle material behavior was developed. The approach was to imbed a local heterogeneous region surrounding the crack tip into an anisotropic elastic continuum. This (1) permits an explicit analysis of the micromechanical processes involved in the fracture, and (2) remains simple enough to be useful in practical computations. Computations for arbitrary flaw size and orientation under arbitrary applied loads were performed. The mechanical properties were those of graphite epoxy. With the rupture properties arbitrarily varied to test the capabilities of the model to reflect real fracture modes, it was shown that fiber breakage, matrix crazing, crack bridging, matrix-fiber debonding, and axial splitting can all occur during a period of (gradually) increasing load prior to catastrophic failure. The calculations also reveal the sequential nature of the stable crack growth process proceding fracture.

Kanninen, M. F.↗

Use of LANDSAT data to define soil boundaries in Carroll County, Missouri

Bands 4, 5 and 7 false color composite photographs were prepared using data from LANDSAT scenes acquired during April 1977 and April 1981 on computer compatible tapes, and these color composites were compared with band 7 black and white photographs prepared for the entire county. Delineations of soil boundaries at the soil association level were achieved using LANDSAT spectral reflectance data and slope maps for a portion of Carroll County, Missouri. Forty two spectral reflectance classes from April 1977 LANDSAT data were overlaid on digitized slope maps of nine USGS 7.5 minute series topographic quadrangle slope maps to achieve boundary delineations of the soil associations.

Davidson, S. E.↗

AIDDE the Ames Interactive Dynamic Display Editor

This paper describes the design and development of the Ames Interactive Dynamic Display Editor language (AIDDE). AIDDE and its associated tools are a software system that facilitates the interactive creation and use of real-time displays. For the present purposes, real-time displays are pictures on a CRT that change over time to reflect the state of a system. A graphics tree describes a display. Display dynamics are specified by attaching expressions to the tree. Offline, AIDDE is used to draw displays, define display dynamics, and generate host computer source code and a representation of the tree convenient for use in a graphics device. At run time, the compiled host code passes the results of the expressions to a graphics device to modify the tree. The graphics processor repeatedly traverses the tree to draw a changing display on the CRT. Several real-time displays have been implemented using AIDDE with good results.

Globus, A.↗

A PC-based hardware implementation of the maximum-likelihood classifier for the Shuttle Ice Detection System

A PC-based near-real time implementation of a two-channel maximum-likelihood classifier is described. The statistical distribution of the reflectance characteristics of ice, frost, and water formation on spray-on-foam-insulation, which covers the External Tank surface of the Space Shuttle, is acquired. The classification technique is based on these statistics. The computer, set in either a training or a classifying mode, learns the statistics of the various classes, or produces a color-coded image denoting the respective categories of classification. The classified results are memory-mapped for efficiency. The speed of the classification process is only limited by the speed of the digital frame grabber and the software that interfaces the frame grabber to the monitor. The process took 4 seconds for a 512 x 480 pixel image.

Jaggi, S.↗

Evaluating scheduling algorithms for traffic with heterogeneous performance objectives

Two types of network traffic are considered: traffic with deadlines, for which the most important performance objective is based on loss rate, and packets without deadlines, for which the most important performance objective is based on mean delay. An optimal scheduling algorithm is presented to minimize weighted loss rate and weighted mean delay in the queues that form at the switches and at the network access points of a packet-switched network, where weights reflect the relative importance of packets. Although not practical for implementation, the algorithm is intended as a standard for the comparison of the performance of other scheduling algorithms. The algorithm is more general and lower computational complexity than previously published algorithms, enabling performance evaluation of some important scenarios that could not previously have been considered. Using the optimal performance results of this algorithm, the performance of the first-come-first-served, static priority, and earliest deadline first scheduling algorithms is evaluated. The results suggest that network efficiency could be improved by using a more sophisticated heuristic scheduling algorithm rather than one of the aforementioned algorithms.

Peha, Jon M.↗

Calculated sensitivities of several optical radiometric indices for vegetation canopies

The present study employs a radiative transfer model for a vegetation canopy to compute several quantities used in remote sensing applications and to determine the sensitivity of these radiometric quantities to several of the important problem parameters. Attention is given to the ratio of near IR to visible reflected intensities in the nadir direction, the ratio of the fraction of incident energy reflected in the near IR to that in the visible, the normalized difference between the near IR and visible nadir-reflected intensities, and the visible intensity transmitted in a given downward direction. A realistic radiative transfer model is proposed for calculating these radiometric quantities. With these models, the sensitivity of the reflected and transmitted quantities to various canopy and illumination conditions are then determined. The sensitivity of the calculated quantities are presented as a function of the leaf area index of the canopy, and, for the reflected quantities, also as a function of the fraction of visible light absorbed in the canopy.

Shultis, J. K.↗

A grid quality manipulation system

A grid quality manipulation system is described. The elements of the system are the measures by which quality is assessed, the computer graphic display of those measures, and the local grid manipulation to provide a response to the viewed quality indication. The display is an overlaid composite where the region is first covered with colors to reflect the values of the quality indicator, the grid is then placed on top of those colors, and finally a control net is placed on top of everything. The net represents the grid in terms of the control point form of algebraic grid generation. As a control point is moved, both the grid and the colored quality measures also move. This is a real time dynamic action so that the consequences of the manipulation are continuously seen.

Lu, Ning↗

Verification Assessment of Flow Boundary Conditions for CFD Analysis of Supersonic Inlet Flows

Boundary conditions for subsonic inflow, bleed, and subsonic outflow as implemented into the WIND CFD code are assessed with respect to verification for steady and unsteady flows associated with supersonic inlets. Verification procedures include grid convergence studies and comparisons to analytical data. The objective is to examine errors, limitations, capabilities, and behavior of the boundary conditions. Computational studies were performed on configurations derived from a "parameterized" supersonic inlet. These include steady supersonic flows with normal and oblique shocks, steady subsonic flow in a diffuser, and unsteady flow with the propagation and reflection of an acoustic disturbance.

Slater, John W.↗

Squat Biomechanical Modeling Results from Exercising on the Hybrid Ultimate Lifting Kit

Long duration space travel will expose astronauts to extended periods of reduced gravity. Since gravity is not present to aid loading, astronauts will use resistive and aerobic exercise regimes for the duration of the space flight to minimize loss of bone density, muscle mass and aerobic capacity that occurs during exposure to a reduced gravity environment. Unlike the International Space Station (ISS), the area available for an exercise device in the next generation of spacecraft is limited and therefore compact resistance exercise device prototypes are being developed. The Advanced Resistive Exercise Device (ARED) currently on the ISS is being used as a benchmark for the functional performance of these new devices. Biomechanical data collection and computational modeling aid the device design process by quantifying the joint torques and the musculoskeletal forces that occur during exercises performed on the prototype devices. The computational models currently under development utilize the OpenSim software, an open source code for musculoskeletal modeling, with biomechanical input data from test subjects for estimation of muscle and joint loads. The subjects are instrumented with reflective markers for motion capture data collection while exercising on the Hybrid Ultimate Lifting Kit (HULK) prototype device. Ground reaction force data is collected with force plates under the feet and device loading is recorded through load cells internal to the HULK. Test variables include applied device load, narrow or wide foot stance, slow or fast cadence and the harness or long bar interface between the test subject and the device. Data is also obtained using free weights for a comparison to the resistively loaded exercise device. This data is input into the OpenSim biomechanical model, which has been scaled to match the anthropometrics of the test subject, to calculate the body loads. The focus of this presentation is to summarize the results from the full squat exercises across the different test variables.

Bioengineering↗

A Principal-Component-Based Radiative Transfer Model (PCRTM) for Hyperspectral Shortwave and Longwave Satellite Sensors and Its Applications

The radiative transfer model (RTM) or forward model is an essential component in satellite remote sensing. For modern hyperspectral remote sensors, fast and accurate RTMs are needed due to a large number of spectral dimensions and high spatial resolutions. We will describe a Principal Component-based radiative transfer model (PCRTM) which can simulate the top-of-atmosphere (TOA) radiance or reflectance spectra 250 nm to 2000 micrometers quickly and accurately. The PCRTM has been demonstrated to be extremely accurate, compared to the line-by-line RTM benchmarks, and the former is several orders more computationally efficient than the latter. We will demonstrate how the PCRTM and the associated inversion algorithms are used to infer atmospheric temperature, moisture, and trace gas profiles, as well as cloud and surface properties from hyperspectral IR sounders such as Atomspheric Infrared Souder (AIRS) and Cross-track Infrared Sounder (CrIS). High-quality climate records for a 20-year duration have been derived from these IR hyperspectral data. Finally, we will show some examples of using PCRTM to retrieve cloud properties from Earth Surface Mineral Dust Source Investigation (EMIT) and its applicability of PCRTM to future missions such as the CLARREO (Climate Absolute Radiance and Refractivity Observatory) Pathfinder (CPF) CPF and the Surface Biology and Geology (SBG).

Xu Liu↗