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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 1,585 records · Page 88
All sourcesNASA NTRSDOE OSTI
DOE OSTI2021

Polyphenols Weaken Pea Protein Gel by Formation of Large Aggregates with Diminished Noncovalent Interactions

Polyphenols are well-known native cross-linkers and gel strengthening agents for many animal proteins. However, their role in modifying plant protein gels remains unclear. In this study, multiple techniques were applied to unravel the influence of green tea polyphenols (GTP) on pea protein gels and the underlying mechanisms. We found that the elasticity and viscosity of pea protein gels decreased with increased GTP. The protein backbone became less rigid when GTP was present based on shortened T 1ρ H in relaxation solid-state NMR measurements. Electron microscopy and small-angle X-ray scattering showed that gels weakened by GTP possessed disrupted networks with the presence of large protein aggregates. Solvent extraction and molecular dynamic simulation revealed a reduction in hydrophobic interactions and hydrogen bonds among proteins in gels containing GTP. The current findings may be applicable to other plant proteins for greater control of gel structures in the presence of polyphenols, expanding their utilization in food and biomedical applications.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2017

Hydrothermal Synthesis and Characterization of a New Strandberg-type Diphosphopentamolybdate (C{sub 6}N{sub 3}H{sub 18}){sub 2}[P{sub 2}Mo{sub 5}O{sub 23}] · 6H{sub 2}O

An inorganic-organic hybrid material formulated as (C{sub 6}N{sub 3}H{sub 18}){sub 2}[P{sub 2}Mo{sub 5}O{sub 23}] · 6H{sub 2}O, has been hydrothermally synthesized and characterized by single crystal X-ray diffraction technique, IR spectrum, thermogravimetric analysis and UV-visible spectroscopy. The structure consists of diphosphopentamolybdate Strandberg type polyoxoanions [P{sub 2}Mo{sub 5}O{sub 23}]{sup 6–}, protonated 1-(2-aminoethyl)piperazine cations and six crystallization water molecules. These anions are connected with the organic amine through hydrogen bonding interactions between the hydrogen atoms of the organic molecules and the oxygen atoms of the polyoxoanion and water molecules which generate a three-dimensional network.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2014

Cholesterol enhances surface water diffusion of phospholipid bilayers

Elucidating the physical effect of cholesterol (Chol) on biological membranes is necessary towards rationalizing their structural and functional role in cell membranes. One of the debated questions is the role of hydration water in Chol-embedding lipid membranes, for which only little direct experimental data are available. Here, we study the hydration dynamics in a series of Chol-rich and depleted bilayer systems using an approach termed {sup 1}H Overhauser dynamic nuclear polarization (ODNP) NMR relaxometry that enables the sensitive and selective determination of water diffusion within 5–10 Å of a nitroxide-based spin label, positioned off the surface of the polar headgroups or within the nonpolar core of lipid membranes. The Chol-rich membrane systems were prepared from mixtures of Chol, dipalmitoyl phosphatidylcholine and/or dioctadecyl phosphatidylcholine lipid that are known to form liquid-ordered, raft-like, domains. Our data reveal that the translational diffusion of local water on the surface and within the hydrocarbon volume of the bilayer is significantly altered, but in opposite directions: accelerated on the membrane surface and dramatically slowed in the bilayer interior with increasing Chol content. Electron paramagnetic resonance (EPR) lineshape analysis shows looser packing of lipid headgroups and concurrently tighter packing in the bilayer core with increasing Chol content, with the effects peaking at lipid compositions reported to form lipid rafts. The complementary capability of ODNP and EPR to site-specifically probe the hydration dynamics and lipid ordering in lipid membrane systems extends the current understanding of how Chol may regulate biological processes. One possible role of Chol is the facilitation of interactions between biological constituents and the lipid membrane through the weakening or disruption of strong hydrogen-bond networks of the surface hydration layers that otherwise exert stronger repulsive forces, as reflected in faster surface water diffusivity. Another is the concurrent tightening of lipid packing that reduces passive, possibly unwanted, diffusion of ions and water across the bilayer.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2023

Inferring colloidal interaction from scattering by machine learning

A machine learning solution for the potential inversion problem in elastic scattering is outlined. The inversion scheme consists of two major components, a generative network featuring a variational autoencoder which extracts the targeted static two-point correlation functions from experimentally measured scattering cross sections, and a Gaussian process framework which probabilistically infers the relevant structural parameters from the inverted correlation functions. Via a case study of charged colloidal suspensions, the feasibility of this approach for quantitative study of molecular interaction is critically benchmarked and its merit over existing deterministic approaches, in terms of numerical accuracy and computationally efficiency, is demonstrated.

36 MATERIALS SCIENCE↗
DOE OSTI2023

Plant Cell Biology International Meeting 2022

There is a strong need to develop the knowledge base that will enable the rational design of improved crop species for sustainable agriculture and biomass production. To attain this goal, researchers must learn how plant cells integrate metabolism and cellular dynamics during growth and in response to environmental challenges. Meeting these goals require data sharing and the development and training of faculty, post-doctoral fellows, graduate and undergraduate students in state-of-the-art quantitative integrative cell biology methods. The inaugural Plant Cell Biology International (PCBI) meeting capitalized on the interaction between two well-established plant cell biology communities across the Atlantic, the Midwest Plant Cell Dynamics (PCD) and the European Network for Plant Endomembrane Research (ENPER) and provided a framework to meet these goals. The conference took place in person successfully during August 1-5th 2022 in Crete, Greece. The conference offered opportunities for undergraduate and graduate students, postdocs, young investigators across the globe to present their results and interact across different disciplines. The conference provided an open and inclusive forum for oral presentations that allowed all labs to share research results. It was attended over 80 % by students, postdocs and young investigators. Workshops on best practices for image acquisition and processing pipelines, publication guidelines by scientific journal editors, professional development and well-being benefited the participants at large. Overall, this was the inaugural joint Plant Cell Biology International conference that for the first time officially brought together plant cell biologists to discuss opportunities and challenges in the field to gain a mechanistic understanding of complex biological processes and advance sustainable agriculture. Due to its success, it was rescheduled for 2025 in Crete, to continue strengthening the plant cell biology community and exchanging knowledge and expertise across the globe.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2018

SWNT Networks with Polythiophene Carboxylate Links for High-Performance Silicon Monoxide Electrodes

Carboxylated polythiophenes, such as poly[3-(potassium-4-butanoate) thiophene] (PPBT), play a critical role in securely connecting single-walled carbon nanotube (SWNT) electrical networks onto the surface of carbon-coated silicon monoxide (c-SiO x ). These connections are a function of the materials’ surface chemistries and resultant physical/chemical bonding through favorable molecular interactions. Specifically, the PPBT $π$-conjugated backbone and alkyl side chain carboxylate moieties (COO-), respectively, physically interact with the SWNT and c-SiO x carbon layer $π$-electron-rich surfaces, and chemically bind to surface hydroxyl (-OH) species of the c-SiO x electroactive materials to form a carboxylate bond. This approach effectively captured pulverized particles that form during battery operation and beneficially suppressed the thickness change that electrodes typically undergo. The resultant electrodes exhibited superior electrochemical performance, which was ascribed to stable SEI layer formation, reduced electrode resistance, and improved electrode kinetics. Moreover, electrodes fabricated by blending 30 wt % of c-SiO x with graphite using <3 wt % binder exhibited remarkable performance in both coin-type half-cell and pouch-type full-cell systems. Finally, the concept that introduces robust SWNT electrical networks with PPBT carboxylate linkages suggests a feasible approach for the design of practical, high-performance, and high-capacity anodes for battery applications.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
NASA NTRS2015

Assessing and Promoting Functional Resilience in Flight Crews During Exploration Missions

The NASA Human Research Program works to mitigate risks to health and performance on extended missions. However, research should be directed not only to mitigating known risks, but also to providing crews with tools to assess and enhance resilience, as a group and individually. We can draw on ideas from complexity theory to assess resilience. The entire crew or the individual crewmember can be viewed as a complex system composed of subsystems; the interactions between subsystems are of crucial importance. Understanding the interactions can provide important information even in the absence of complete information on the component subsystems. Enabled by advances in noninvasive measurement of physiological and behavioral parameters, subsystem monitoring can be implemented within a mission and during training to establish baselines. Coupled with mathematical modeling, this can provide assessment of health and function. Since the web of physiological systems (and crewmembers) can be interpreted as a network in mathematical terms, we can draw on recent work that relates the structure of such networks to their resilience (ability to self-organize in the face of perturbation). Some of the many parameters and interactions to choose from include: sleep cycles, coordination of work and meal times, cardiorespiratory rhythms, circadian rhythms and body temperature, stress markers and cognition, sleep and performance, immune function and nutritional status. Tools for resilience are then the means to measure and analyze these parameters, incorporate them into models of normal variability and interconnectedness, and recognize when parameters or their couplings are outside of normal limits.

Shelhamer, M.↗
DOE OSTI2019

Perturbation of Hydrogen-Bonding Networks over Supported Lipid Bilayers by Poly(allylamine hydrochloride)

Water is vital to many biochemical processes and is necessary for driving fundamental interactions of cell membranes with their external environments, yet it is difficult to probe the membrane/water interface directly and without the use of external labels. Here, we employ vibrational sum frequency generation spectroscopy to understand the role of interfacial water molecules above bilayers formed from zwitterionic (phosphatidylcholine) and anionic (phosphatidylglycerol, PG, and phosphatidylserine, PS) lipids as they are exposed to the common polycation poly(allylamine hydrochloride) (PAH) in 100 mM NaCl. We show that as the concentration of PAH is increased, the interfacial water molecules are irreversibly displaced and find that it requires 10 times more PAH to displace interfacial water molecules from membranes formed from purely zwitterionic lipids when compared to membranes that contain the anionic PG and PS lipids. This outcome is likely due to the difference in (1) the energy with which water molecules are bound to the lipid headgroups, (2) the number of water molecules bound to the headgroups, which is related to the headgroup area, and (3) the electrostatic interactions between the PAH molecules and the negatively charged lipids that are favored when compared to the zwitterionic lipid headgroups. The findings presented here contribute to establishing causal relationships in nanotoxicology and to understanding, controlling, and predicting the initial steps that lead to the lysis of cells exposed to membrane-disrupting polycations or to transfection.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2014

International Conference on Human Resource Development for Nuclear Power Programmes: Strategies for Education and Training, Networking and Knowledge Management

The report includes a summary of the overall workshop results and also copies of the two papers and interactive presentations given by BNL staff at the meeting. The two presentations were titled ''The value of the Junior Professional Officer (JPO) program to the IAEA and its Member States'' and ''Promoting intercultural competencies''.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗
NASA NTRS1976

Simulation and modeling of the deep space receiver interaction with channel decoding performance

Computer models were developed in an attempt to reproduce the sequential decoder computation curve of Deep Space Network (DSN) ground station receivers, by simulation of the binary data output of the Gaussian channel with the carrier phaselock loop and the subcarrier demodulator assembly. Simulations were run at bit rates equal to the powers of 2 from 8 to 2,048, and agreement with DSN data was generally good above 32 bits per second. Simulation results at data rates of 8, 16, and 32 bits per second did not closely match experimental data. This simulation provides a more accurate prediction of DSN computation lengths than either current mathematical models or simulations without both the subcarrier demodulator and carrier loop.

Jones, H. W., Jr.↗
DOE OSTI2015

Solution Structure of the HIV-1 Intron Splicing Silencer and Its Interactions with the UP1 Domain of Heterogeneous Nuclear Ribonucleoprotein (hnRNP) A1

Splicing patterns in human immunodeficiency virus type 1 (HIV-1) are maintained through cis regulatory elements that recruit antagonistic host RNA-binding proteins. The activity of the 3' acceptor site A7 is tightly regulated through a complex network of an intronic splicing silencer (ISS), a bipartite exonic splicing silencer (ESS3a/b), and an exonic splicing enhancer (ESE3). Because HIV-1 splicing depends on protein-RNA interactions, it is important to know the tertiary structures surrounding the splice sites. Herein, we present the NMR solution structure of the phylogenetically conserved ISS stem loop. ISS adopts a stable structure consisting of conserved UG wobble pairs, a folded 2X2 (GU/UA) internal loop, a UU bulge, and a flexible AGUGA apical loop. Calorimetric and biochemical titrations indicate that the UP1 domain of heterogeneous nuclear ribonucleoprotein A1 binds the ISS apical loop site-specifically and with nanomolar affinity. Atogether, this work provides additional insights into how HIV-1 uses a conserved RNA structure to commandeer a host RNA-binding protein.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2022

Stochastic Strategic Participation of Active Distribution Networks With High-Penetration DERs in Wholesale Electricity Markets

With the increasing penetration of distributed energy resources (DERs), traditional distribution networks as load-serving entities in wholesale electricity markets, now evolve towards active distribution networks (ADNs) which can proactively participate in wholesale markets by optimally controlling the DERs in their networks. A stochastic bilevel optimization model is proposed in this paper for the strategic participation of ADNs and DERs to provide energy and grid services in wholesale electricity markets. The bilevel optimization model can capture the interactions between the ADN and the wholesale energy and ancillary service markets, considering the uncertainties of DERs in the ADN. In the upper-level model, the ADN makes optimal decisions on energy and reserve bidding considering the availability, uncertainties, and flexibility of DERs. The joint energy and reserve market-clearing of the independent system operator (ISO) is modeled as the lower-level problem. Using strong duality theory and Karush-Kuhn Tucker (KKT) conditions, the proposed bilevel optimization problem is reformulated as mathematical programming with equilibrium constraints (MPEC) problem and further converted into a computationally-solvable mixed-integer second-order-cone programming (MISOCP) model. The simulation results demonstrate the effectiveness of the model and the interactions between an ADN and wholesale electricity markets.

active distribution network↗
NASA NTRSDate not supplied

Three Years of Airborne Observations During NASA Activate: A Statistical Summary of Chemical, Optical, and Microphysical Aerosol Properties Over the Western North Atlantic Ocean

Airborne observations are critical to understanding Earth’s climate system and surface-level air quality by providing both spatial and vertical information that is not possible through ground measurement networks or satellite observations. Airborne platforms allow assessments of long-range transport, vertical redistribution, boundary-layer dynamics, and cloud-aerosol-interactions that are critical to model evaluation and satellite validation. Still, the high cost and effort of aircraft operations can limit measurement campaigns to short, focused time periods. Multiple deployments are often necessary for seasonal comparisons, and results can be limited if target phenomenon are infrequent. Subsequent analyses typically focus on case studies, especially if deployment conditions are climatologically anomalous. The NASA ACTIVATE (Aerosol Cloud meTeorology Interactions oVer the western ATlantic Experiment) mission was designed to overcome these limitations by operating semi-continuously over multiple months during multiple seasons. Flight plans were intentionally simple, repetitive, and systematic to provide a statistically robust dataset that could be utilized similarly to a ground-network. Here, we present an overview of three years (2020-2022) of aerosol measurements from the NASA HU-25 Falcon aircraft supporting the ACTIVATE mission. Data from 179 flights were considered, the majority of which were based at NASA Langley Research Center and flown locally over the Wester North Atlantic Ocean just east of Hampton, VA, USA. Airmass characteristics tended to transition from continental outflow near the coast to mostly marine over the open ocean. Seasonal, diurnal, spatial, and vertical trends in aerosol microphysical, optical, and chemical properties are discussed in the context of synoptic scale meteorology. Statistical benefits of the ACTIVATE sampling strategy are discussed with regard to future model evaluation.

Luke D Ziemba↗
DOE OSTI2012

Charge exchange reactions and applications to astrophysics

Neutrino-induced reactions have been known to play important roles as the neutrino process on the nucleosynthesis in core collapsing supernovae (SNe) explosions because expected neutrino flux and energy are sufficiently high enough to excite many relevant nuclei in spite of small cross sections of the weak interaction. However, we do not have enough data for the neutrino reaction to be exploited in the network calculation. Only a sparse data in the relevant energy range is known, in specific, for {sup 12}C. Therefore we have to rely on theoretical estimation of the reaction, which has two different modes, charge current (CC) and neutral current (NC). In particular, CC reactions are closely related to charge exchange reactions (CEXRs) which are feasible in the experiment, such as, (p,n) or (n,p) reactions. These CEXRs are usually dominated by the Gamow-Teller (GT) transition in the lower energy region. In this respect, any theoretical approaches for the neutrino reaction should be investigated for the CEXR because we have and expect more useful experimental data. After confirming our models to the GT strength deduced from the CEXR, we calculated neutrino-induced reactions in the energy range below the quasielastic region for nuclei of astrophysical importance. Our calculations are carried out with the Quasi-particle Random Phase Approximation (QRPA), which successfully described the nuclear beta decays of relevant nuclei. To describe neutrino-nucleus reactions, general multipole transitions by the weak interaction are considered for CC and NC reactions. Both reactions are described in a theoretical framework. Our results are shown to well reproduce the data from CEXRs and the sparse experimental data related to the neutrino-induced reaction, and further extended for neutrino reactions on various nuclear targets. Parts of the results are reported in this talk.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2014

Syntrophic interactions and mechanisms underpinning anaerobic methane oxidation: targeted metaproteogenomics, single-cell protein detection and quantitative isotope imaging of microbial consortia

Syntrophy and mutualism play a central role in carbon and nutrient cycling by microorganisms. Yet, our ability to effectively study symbionts in culture has been hindered by the inherent interdependence of syntrophic associations, their dynamic behavior, and their frequent existence at thermodynamic limits. Now solutions to these challenges are emerging in the form of new methodologies. Developing strategies that establish links between the identity of microorganisms and their metabolic potential, as well as techniques that can probe metabolic networks on a scale that captures individual molecule exchange and processing, is at the forefront of microbial ecology. Understanding the interactions between microorganisms on this level, at a resolution previously intractable, will lead to our greater understanding of carbon turnover and microbial community resilience to environmental perturbations. In this project, we studied an enigmatic syntrophic association between uncultured methane-oxidizing archaea and sulfate-reducing bacteria. This environmental archaeal-bacterial partnership represents a globally important sink for methane in anoxic environments. The specific goals of this project were organized into 3 major tasks designed to address questions relating to the ecophysiology of these syntrophic organisms under changing environmental conditions (e.g. different electron acceptors and nutrients), primarily through the development of microanalytical imaging methods which enable the visualization of the spatial distribution of the partners within aggregates, consumption and exchange of isotopically labeled substrates, and expression of targeted proteins identified via metaproteomics. The advanced tool set developed here to collect, correlate, and analyze these high resolution image and isotope-based datasets from methane-oxidizing consortia has the potential to be widely applicable for studying and modeling patterns of activity and interactions across a broad range of spatially structured microbial partnerships, including other syntrophic associations, microbial mats, biofilms, and plant-microbe or animal-microbe symbioses in nature.

03 NATURAL GAS↗
NASA NTRS1999

Early animal evolution: emerging views from comparative biology and geology

The Cambrian appearance of fossils representing diverse phyla has long inspired hypotheses about possible genetic or environmental catalysts of early animal evolution. Only recently, however, have data begun to emerge that can resolve the sequence of genetic and morphological innovations, environmental events, and ecological interactions that collectively shaped Cambrian evolution. Assembly of the modern genetic tool kit for development and the initial divergence of major animal clades occurred during the Proterozoic Eon. Crown group morphologies diversified in the Cambrian through changes in the genetic regulatory networks that organize animal ontogeny. Cambrian radiation may have been triggered by environmental perturbation near the Proterozoic-Cambrian boundary and subsequently amplified by ecological interactions within reorganized ecosystems.

Non-NASA Center↗