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At least 1,567 records · Page 87

Onboard Data Compression of Synthetic Aperture Radar Data: Status and Prospects

Synthetic aperture radar (SAR) instruments on spacecraft are capable of producing huge quantities of data. Onboard lossy data compression is commonly used to reduce the burden on the communication link. In this paper an overview is given of various SAR data compression techniques, along with an assessment of how much improvement is possible (and practical) and how to approach the problem of obtaining it. Synthetic aperture radar (SAR) instruments on spacecraft are capable of acquiring huge quantities of data. As a result, the available downlink rate and onboard storage capacity can be limiting factors in mission design for spacecraft with SAR instruments. This is true both for Earth-orbiting missions and missions to more distant targets such as Venus, Titan, and Europa. (Of course for missions beyond Earth orbit downlink rates are much lower and thus potentially much more limiting.) Typically spacecraft with SAR instruments use some form of data compression in order to reduce the storage size and/or downlink rate necessary to accommodate the SAR data. Our aim here is to give an overview of SAR data compression strategies that have been considered, and to assess the prospects for additional improvements.

Klimesh, Matthew A.↗

NASA-ISRO Synthetic Aperture Radar (NISAR) Mission

NISAR is a multi-disciplinary Earth-observing radar mission that makes global measurements of land surface changes that will greatly improve Earth system models. NISAR data will clarify spatially and temporally complex phenomena, including ecosystem disturbances, ice sheet collapse, and natural hazards including earthquakes, tsunamis, volcanoes, and landslides. It provides societally relevant data that will enable better protection of life and property. The mission, a NASA-ISRO partnership, uses two fully polarimetric SARs, one at L-band (L-SAR) and one at S-band (S-SAR), in exact repeating orbits every 12 days that allows interferometric combination of data on repeated passes. NASA provides the L SAR; a shared deployable reflector; an engineering payload that supports mission-specific data handling, navigation and communication functions; science observation planning and L SAR data processing. ISRO provides the S-SAR, spacecraft, launch vehicle, satellite operations, and S-SAR data processing. The mission will be launched from the Satish Dhawan Space Centre, Sriharikota, India. Mission development has addressed many unique challenges and incorporates many “firsts” for a jointly-developed free-flyer radar science mission.

Sarma, C V H S↗

Flood Detection with Synthetic Aperture Radar: A Case Study of Houston, Texas Following Hurricane Harvey (2017) using C- and X-Band Observations

Hurricane Harvey produced record-breaking rainfall of up to 60 inches resulting in extensive flooding in Houston, Texas, in late August and early September of 2017. The slow forward motion of the storm following landfall left much of the area unobservable to optical remote sensing instruments for several days due to cloud cover. The active nature of Synthetic Aperture Radar (SAR) instruments allows for observations through clouds, which can supplement efforts to estimate hurricane-induced flood impacts. A growing fleet of SAR constellations has helped lower the latency of imagery following a hurricane, allowing for more timely detections of flooding to help support emergency response efforts. In this study, we leverage publicly available C-band SAR observations from the European Space Agency’s Sentinel-1B (S1B) satellite, collected on 30 August, and X-band SAR imagery collected on 1 September by the Airbus TanDEM-X (TDX) satellite made available through the NASA Commercial Smallsat Data Acquisition (CSDA) program. For each dataset, one co-polarized, StripMap, Radiometric Terrain Corrected (RTC) image was used to create a binary water/no water classification map by referencing permanent water in the Cropland Data Layer (CDL) dataset to determine thresholds. A validation dataset of randomly distributed “ground truth” points was generated using optical imagery from PlanetScope on 31 August, where the domain had relatively little cloud cover. We found that the S1B- and TDX-derived open water maps achieved overall accuracies of 94.17% and 91.57%, respectively. The variation in performance is attributed to both the penetrative abilities of C- and X-band SAR wavelengths in vegetated areas and the increased spatial resolution of the commercial SAR (~3 m) over Sentinel-1 (30 m). While publicly available Sentinel-1 observations are commonly relied upon in response and recovery efforts, these results suggest that including commercial X-band SAR imagery could be beneficial by providing both increased spatial resolution and more frequent revisits when deriving post-event flood mapping products.

Alexander M Melancon↗

Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects

SARS-CoV-2 is one of three coronaviruses that have crossed the animal-to-human barrier and caused widespread disease in the past two decades. The development of a universal human coronavirus vaccine could prevent future pandemics. We characterize 198 antibodies isolated from four COVID-19+ subjects and identify 14 SARS-CoV-2 neutralizing antibodies. One targets the N-terminal domain (NTD), one recognizes an epitope in S2, and 11 bind the receptor-binding domain (RBD). Three anti-RBD neutralizing antibodies cross-neutralize SARS-CoV-1 by effectively blocking binding of both the SARS-CoV-1 and SARS-CoV-2 RBDs to the ACE2 receptor. Using the K18-hACE transgenic mouse model, we demonstrate that the neutralization potency and antibody epitope specificity regulates the in vivo protective potential of anti-SARS-CoV-2 antibodies. All four cross-neutralizing antibodies neutralize the B.1.351 mutant strain. Thus, our study reveals that epitopes in S2 can serve as blueprints for the design of immunogens capable of eliciting cross-neutralizing coronavirus antibodies.

60 APPLIED LIFE SCIENCES↗

Evaluation of co-circulating pathogens and microbiome from COVID-19 infections

Co-infections or secondary infections with SARS-CoV-2 have the potential to affect disease severity and morbidity. Additionally, the potential influence of the nasal microbiome on COVID-19 illness is not well understood. In this study, we analyzed 203 residual samples, originally submitted for SARS-CoV-2 testing, for the presence of viral, bacterial, and fungal pathogens and non-pathogens using a comprehensive microarray technology, the Lawrence Livermore Microbial Detection Array (LLMDA). Eighty-seven percent of the samples were nasopharyngeal samples, and 23% of the samples were oral, nasal and oral pharyngeal swabs. We conducted bioinformatics analyses to examine differences in microbial populations of these samples, as a proxy for the nasal and oral microbiome, from SARS-CoV-2 positive and negative specimens. We found 91% concordance with the LLMDA relative to a diagnostic RT-qPCR assay for detection of SARS-CoV-2. Sixteen percent of all the samples (32/203) revealed the presence of an opportunistic bacterial or frank viral pathogen with the potential to cause co-infections. The two most detected bacteria, Streptococcus pyogenes and Streptococcus pneumoniae , were present in both SARS-CoV-2 positive and negative samples. Human metapneumovirus was the most prevalent viral pathogen in the SARS-CoV-2 negative samples. Sequence analysis of 16S rRNA was also conducted to evaluate bacterial diversity and confirm LLMDA results.

59 BASIC BIOLOGICAL SCIENCES↗

Calculated and observed features of stable auroral red arcs during three geomagnetic storms.

Satellite electron temperature and density data are used to calculate the structure of several stable auroral red arcs (SAR arcs) according to the thermal conduction model of the arc. The calculated lambda 6300 emission rates are compared with ground-based photometric observations taken at the same time and in the vicinity of the satellite crossings of the arcs. The SAR arcs analyzed include a range of lambda 6300 intensities, geographical locations, and times during the associated geomagnetic storm. In addition, satellite data were obtained at different altitudes over and within the SAR-arc region. Enhanced electron temperatures within or on the equatorward edge of an electron-density depression are common features of all the SAR arcs examined. There is general agreement between the calculated and observed lambda 6300 emission features for SAR arcs observed during the geomagnetic storm periods of Oct. 29 to Nov. 2, 1968, May 14-15, 1969, and Mar. 8-9, 1970. For these SAR arcs, thermal conduction from the magnetosphere alone is sufficient to excite the lambda 6300 emission to its observed intensity.

Roble, R. G.↗

A comparative study of real-time spaceborne synthetic aperture radar processing techniques

A review of various spaceborne synthetic aperture radar (SAR) processing algorithms and their associated real-time SAR processor architectures is given in this paper. The processing complexity for each real-time SAR processor is presented next. A complexity comparison is then given based on the Seasat SAR parameters. It is shown that the frequency/time domain hybrid fast correlation and the two-stage fast Fourier transform (FET) approaches are the two most cost-effective choices for real-time spaceborne SAR processing. Finally, a discussion on future development trends in real-time spaceborne SAR processing is given.

Liu, K. Y.↗

A comparative study on synthetic aperture radar and optical imagery of ocean waves

The ocean imaging capability of synthetic aperture radar (SAR) is examined in terms of an intercomparison between simultaneous, spatially collocated images of a coastal ocean scene, as recorded by aerial photography and aircraft-borne SAR. Based on a detailed study of these images, this paper examines various local features of oceanographic interest as they are imaged by the two methods. This provides information not available in the usual comparisons of normalized SAR and single point buoy spectra. In addition, aspects of the intensity wavenumber spectra of the two images are examined and discussed. An interesting and surprising conclusion arising from the comparison study is the ability of the SAR to image accurately non-uniform (possibly nonlinear) wave features which are imaged by the aerial photography. This result should have important implications on the development of SAR imaging models and the interpretation of the effect of ocean surface motion on the SAR images.

Banner, M. L.↗

Ocean-ice interaction in the marginal ice zone using synthetic aperture radar imagery

Ocean-ice interaction processes in the marginal ice zone (MIZ) by wind, waves, and mesoscale features, such as up/downwelling and eddies are studied using Earth Remote-Sensing Satellite (ERS) 1 synthetic aperture radar (SAR) images and an ocean-ice interaction model. A sequence of seven SAR images of the MIZ in the Chukchi Sea with 3 or 6 days interval are investigated for ice edge advance/retreat. Simultaneous current measurements from the northeast Chukchi Sea, as well as the Barrow wind record, are used to interpret the MIZ dynamics. SAR spectra of waves in ice and ocean waves in the Bering and Chukchi Sea are compared for the study of wave propagation and dominant SAR imaging mechanism. By using the SAR-observed ice edge configuration and wind and wave field in the Chukchi Sea as inputs, a numerical simulation has been performed with the ocean-ice interaction model. After 3 days of wind and wave forcing the resulting ice edge configuration, eddy formation, and flow velocity field are shown to be consistent with SAR observations.

Liu, Antony K.↗

Reduction and coding of synthetic aperture radar data with Fourier transforms

Recently, aboard the Space Radar Laboratory (SRL), the two roles of Fourier Transforms for ocean image synthesis and surface wave analysis have been implemented with a dedicated radar processor to significantly reduce Synthetic Aperture Radar (SAR) ocean data before transmission to the ground. The object was to archive the SAR image spectrum, rather than the SAR image itself, to reduce data volume and capture the essential descriptors of the surface wave field. SAR signal data are usually sampled and coded in the time domain for transmission to the ground where Fourier Transforms are applied both to individual radar pulses and to long sequences of radar pulses to form two-dimensional images. High resolution images of the ocean often contain no striking features and subtle image modulations by wind generated surface waves are only apparent when large ocean regions are studied, with Fourier transforms, to reveal periodic patterns created by wind stress over the surface wave field. Major ocean currents and atmospheric instability in coastal environments are apparent as large scale modulations of SAR imagery. This paper explores the possibility of computing complex Fourier spectrum codes representing SAR images, transmitting the coded spectra to Earth for data archives and creating scenes of surface wave signatures and air-sea interactions via inverse Fourier transformations with ground station processors.

Tilley, David G.↗

S-band Smallsat InSAR Constellation for Surface Deformation Science

Surface deformation studies using repeat-pass interferometric SAR have evolved into a powerful tool for geophysicists studying earthquake fault zones, volcanoes, ice sheet motion, and subterranean aquifers. Longer wavelengths (S-Band and L-Band) are preferred because they do not decorrelate as quickly as shorter wavelengths. Rapid revisit (1-3 days) is preferred because it allows the study of these phenomena at the timescales at which they commonly occur. Global access on such timescales is also required. Vector surface deformation measurements, taken from more than one direction, are a desired feature. This paper describes the conceptual architecture of a longer wave length, Smallsat SAR constellation of up to 12 satellites for rapid revisit surface deformation studies. The key to making such a constellation affordable is to lower launch costs, spacecraft costs, and instrument (SAR) costs. The first two objectives can be achieved using an ESPA-ring class, or Smallsat spacecraft. The third objective requires a SAR instrument sized to fit the mass and volume constraints imposed by such a spacecraft. Current state-of-the-art in miniaturization of electronics means that the radar transmit, receive and data handling functions can easily be implemented in a compact, low mass solution. The most significant challenge in designing a SAR to fit the Smallsat paradigm is in the dimensions of the antenna. The antenna sizing problem is addressed by adopting a smaller antenna than allowed by conventional SAR design rules. The baseline antenna design is simple, requiring no electronic beam-steering or beam-forming capability. Both reflectarray and microstrip patch antenna solutions are considered. The antenna structure is dual-purpose, to limit the overall system mass, with solar panels on the backplane providing power for the radar and spacecraft. The proposed solution easily accommodates radar squint angles of +/-30 degrees for repeat-pass interferometry measurements from multiple direct

Freeman, Anthony↗

Comprehensive Severe Weather Impact Assessment and Monitoring using Synthetic Aperture Radar and Auxiliary Data

Remote sensing datasets, particularly acquired by Synthetic Aperture Radar (SAR) sensors, have become increasingly important in severe weather disaster impact studies given their ability to observe the Earth largely irrespective of weather and sunlight conditions. The reliability of existing SAR change detection products applied on a pair of SAR images is constrained by the limitation of current methods to differentiate and classify disaster specific changes from anthropogenic surface alterations. Moreover, the inherent properties of the sensors, variations in SAR backscatter due to changes in surface conditions, and other factors exacerbate these limitations. We proposed a novel procedure expanding on earlier SAR-based change detection methods to exclude anthropogenic alterations and other sources of ambiguity that might lead to inaccurate mapping of the impacts of severe weather disasters. We applied the proposed procedure that is based on long term interferometric and amplitude-based change detection analyses of Sentinel- 1 SAR imagery to two study sites recently impacted by severe weather disasters (Flooding post severe weather events in urban centers; Hailstorm damage on crops). For the first case study, Sentinel-1 SLC scenes from two flood events in the Houston area (April 2016 flooding event and Hurricane Harvey of August-September 2017) were used to construct a flood map depicting areas repeatedly affected by the flood. Pixels with consistent coherence values in the pre-disaster coherence stack were retained for comparison with the pre- and post-disaster coherence stack and pixels with significant decline (greater than 60%) in coherence values were retained in the final flood map. The findings of the applied technique were calibrated and validated through datasets from NOAA/NWS Service storm reports, aerial imaging (NOAA and Civil Air Patrol), Federal Emergency Management Agency (FEMA) reporting, and targeted collections of NASA’s L-band UAVSAR data. Findings and products derived from the adopted methodology can be useful in disaster response and mitigation activities.

Gebremichael, Esayas↗

Oil Spill Thickness Determination from L-band Synthetic Aperture Radar

Efficient and effective oil spill response requires accurate information regarding slick location, extent, and thickness to direct remediation activities. Of these three, the most challenging to determine is thickness. Ideally, the needed information would be provided by remote sensing instruments, particularly those operating from space. In this study we consider the capability of L-band synthetic aperture radar (SAR) for identifying oil layer thickness for slicks in open water given the range of oil properties and environmental conditions typical in this setting. The goal is to determine layer thickness with precision equivalent to that of the Bonn Agreement Oil Appearance Code. Here we report preliminary results of an ongoing study to determine whether either relative or absolute slick thickness can be determined from L-band SAR. The study has an experimental component, which uses low noise airborne SAR data acquired over slicks to evaluate the capability to determine relative thickness, i.e., to differentiate sheen from zones of varying thicker oil within a slick. The component of the study to evaluate whether absolute thickness can be determined from SAR uses backscatter simulations within a physics- based model of electromagnetic scattering from slicked and unslicked ocean surfaces accounting for oil properties, meteorological conditions, and sea state. As part of the theoretical component of the study, we evaluate the backscatter sensitivity to oil characteristics to determine which properties most influenced the SAR measurements. These results are used to determine whether the oil-to-water ratio or the oil thickness can be quantified with reasonable accuracy based upon SAR backscatter intensities alone or whether it requires calibration to go from relative to absolute thickness. The ratio of the backscatter contrast between clean and slicked ocean surfaces is shown to be sensitive to variations within slicks that well correlate with the oil layer thickness. Determination of absolute thickness is much more challenging given the variation of oil properties as the oil weathers on the sea surface.

Holt, Benjamin↗

Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease

Pan-betacoronavirus neutralizing antibodies may hold the key to developing broadly protective vaccines against novel pandemic coronaviruses and to more effectively respond to SARS-CoV-2 variants. The emergence of Omicron and subvariants of SARS-CoV-2 illustrates the limitations of solely targeting the receptor-binding domain (RBD) of the spike (S) protein. Here, we isolated a large panel of broadly neutralizing antibodies (bnAbs) from SARS-CoV-2 recovered-vaccinated donors, which targets a conserved S2 region in the betacoronavirus spike fusion machinery. Select bnAbs showed broad in vivo protection against all three deadly betacoronaviruses, SARS-CoV-1, SARS-CoV-2, and MERS-CoV, which have spilled over into humans in the past two decades. Structural studies of these bnAbs delineated the molecular basis for their broad reactivity and revealed common antibody features targetable by broad vaccination strategies. These bnAbs provide new insights and opportunities for antibody-based interventions and for developing pan-betacoronavirus vaccines.

60 APPLIED LIFE SCIENCES↗

Sub-Ambient Performance of Potassium Sarcosinate for Direct Air Capture Applications: CO 2 Flux and Viscosity Measurements

Absorption based direct air capture (DAC) technologies have garnered significant interest in recent years due to their scalability, competitive regeneration energy requirements, and low susceptibility to degradation. One of the key advantages of DAC lies in its flexible siting options and the potential to utilize low-value land. However, most of the research in this field has been focused on ambient climate zones (T > 20 °C), overlooking sub-ambient (–30 °C < T < 20 °C) regions, which comprise approximately 70 % of the Earth’s surface. To fully realize the potential of DAC, it is essential to understand how DAC solvents perform in these sub-ambient conditions before any large-scale deployment can be considered. Among DAC solvents of interest, potassium sarcosinate (K-SAR) has emerged as a promising candidate due to its high CO 2 capacity, fast uptake kinetics, compatibility with contactor packing materials, low volatility, good thermal and oxidative stability, and competitive regeneration energy requirements compared to current industry standards. This paper characterizes the CO 2 flux and viscosity of K-SAR at sub-ambient conditions and explores the potential of using ethylene glycol and triethylene glycol as additives to prevent solvent freezing in DAC applications. For 1 M K-SAR, the CO 2 flux ranges between 1.3 × 10 -5 and 8.0 × 10 -5 mol m –2 s –1 across a temperature range of –5 °C to 45 °C. Ethylene glycol is shown to effectively suppress the freezing point of K-SAR below –30 °C with volumetric loadings of the additive as low as 0.1. Here, a reaction model was developed to predict the CO 2 flux for 1 M K-SAR at different temperatures, demonstrating good agreement between experimental and theoretical fluxes.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Immunogenicity and protective efficacy of a rhesus adenoviral vaccine targeting conserved COVID-19 replication transcription complex

The COVID-19 pandemic marks the third coronavirus pandemic this century (SARS-CoV-1, MERS, SARS-CoV-2), emphasizing the need to identify and evaluate conserved immunogens for a pan-sarbecovirus vaccine. Here we investigate the potential utility of a T-cell vaccine strategy targeting conserved regions of the sarbecovirus proteome. We identified the most conserved regions of the sarbecovirus proteome as portions of the RNA-dependent RNA polymerase (RdRp) and Helicase proteins, both of which are part of the coronavirus replication transcription complex (RTC). Fitness constraints suggest that as SARS-CoV-2 continues to evolve these regions may better preserve cross-reactive potential of T-cell responses than Spike, Nucleocapsid, or Membrane proteins. We sought to determine if vaccine-elicited T-cell responses to the highly conserved regions of the RTC would reduce viral loads following challenge with SARS-CoV-2 in mice using a rhesus adenovirus serotype 52 (RhAd52) vector. The RhAd52.CoV.Consv vaccine generated robust cellular immunity in mice and led to significant reductions in viral loads in the nasal turbinates following challenge with a mouse-adapted SARS-CoV-2. These data suggest the potential utility of T-cell targeting of conserved regions for a pan-sarbecovirus vaccine.

60 APPLIED LIFE SCIENCES↗

Proof-of-concept studies with a computationally designed M pro inhibitor as a synergistic combination regimen alternative to Paxlovid

As the SARS-CoV-2 virus continues to spread and mutate, it remains important to focus not only on preventing spread through vaccination but also on treating infection with direct-acting antivirals (DAA). The approval of Paxlovid, a SARS-CoV-2 main protease (M pro ) DAA, has been significant for treatment of patients. A limitation of this DAA, however, is that the antiviral component, nirmatrelvir, is rapidly metabolized and requires inclusion of a CYP450 3A4 metabolic inhibitor, ritonavir, to boost levels of the active drug. Serious drug–drug interactions can occur with Paxlovid for patients who are also taking other medications metabolized by CYP4503A4, particularly transplant or otherwise immunocompromised patients who are most at risk for SARS-CoV-2 infection and the development of severe symptoms. Developing an alternative antiviral with improved pharmacological properties is critical for treatment of these patients. By using a computational and structure-guided approach, we were able to optimize a 100 to 250 μM screening hit to a potent nanomolar inhibitor and lead compound, Mpro61. In this study, we further evaluate Mpro61 as a lead compound, starting with examination of its mode of binding to SARS-CoV-2 M pro . In vitro pharmacological profiling established a lack of off-target effects, particularly CYP450 3A4 inhibition, as well as potential for synergy with the currently approved alternate antiviral, molnupiravir. Development and subsequent testing of a capsule formulation for oral dosing of Mpro61 in B6-K18-hACE2 mice demonstrated favorable pharmacological properties, efficacy, and synergy with molnupiravir, and complete recovery from subsequent challenge by SARS-CoV-2, establishing Mpro61 as a promising potential preclinical candidate.

60 APPLIED LIFE SCIENCES↗

Remote Sensing of Antarctic Sea Ice with Coordinated Aircraft and Satellite Data Acquisitions

Remote sensing of Antarctic sea ice is required to characterize properties of the vast sea ice cover to understand its long-term increase in contrast to the decrease of Arctic sea ice. For this objective, the OIB/TanDEM-X Coordinated Science Campaign (OTASC) was successfully conducted in 2017 to obtain contemporaneous and collocated remote sensing data from NASA's Operation IceBridge (OIB) and the German Aerospace Center (DLR) TanDEM-X Synthetic Aperture Radar (SAR) system at X-band together with Sentinel-1 and RADARSAT-2 SARs at C-band in conjunction with WorldView satellite spectral sensors, surface measurements, and field observations. The Weddell Sea and the Ross Sea were two primary regions while SAR data were also collected over six other regions in the Southern Ocean. Satellite SAR data included both polarimetric and interferometric capabilities to infer snow and sea ice information in three dimensions (3D), while OIB/P-3 aircraft data include snow radar together with altimeter data for snow and sea ice observations in 3D over the Weddell Sea. Across the Ross Sea, IcePOD and AntNZ/York-University flights were carried out together with satellite SAR data acquisitions.

OIB↗