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NASA NTRS1976

Spectra and Fabry-Perot interferometry of AG Carinae and the nebula

Observations of the variable P Cygni-type supergiant and the unique ring nebula around it were made in 1974. Line identifications are tabulated, and an estimated electron density of 1700 per cu cm is combined with a radio flux density to derive a nebular mass of 0.18 (plus or minus 0.04) solar mass on the basis of a distance of 2 kpc. From the data, some ideas of the age and kinematics of the nebula are offered, tracing the evolution of P Cygni supergiants from the youthful prototype past the nebular stage of AG Carinae into more typical, relative old age without recognizable nebular envelopes.

Johnson, H. M.↗

NASA NTRS1977

Composition and evolution of the eucrite parent body - Evidence from rare earth elements

Quantitative modeling of the evolution of rare earth element (REE) abundances in the eucrites, which are plagioclase-pigeonite basalt achondrites, indicates that the main group of eucrites (e.g., Juvinas) might have been produced by approximately 10% equilibrium partial melting of a single type of source region with initial REE abundances which were chondritic relative and absolute. Since the age of the eucrites is about equal to that of the solar system, extensive chemical differentiation of the eucrite parent body prior to the formation of eucrites seems unlikely. If homogeneous accretion is assumed, the bulk composition of the eucrite parent body can be estimated; two estimates are provided, representing different hypotheses as to the ratio of metal to olivine in the parent body. Since a large number of differentiated olivine meteorites, which would represent material from the interior of the parent body, have not been detected, the eucrite parent body is thought to be intact. It is suggested that the asteroid 4 Vesta is the eucrite parent body.

Consolmagno, G. J.↗

DOE OSTI2020

Flat-histogram extrapolation as a useful tool in the age of big data

In this work, we review recent work by the authors to revisit the concept of extrapolating thermodynamic properties of classical systems using statistical mechanical principles. Specifically, we discuss how the combination of these principles with biased sampling techniques enables the prediction of free energy landscapes and other detailed information, such as structural properties, of the system in question. Remarkably accurate estimates of physical properties across a broad range of conditions have been achieved using this approach, greatly reducing the number of simulations needed to explore a given system's behaviour. While approximate, these extrapolations significantly amplify the amount of reasonably accurate information that can be extracted from simulations enabling a small set of them to feed data-intensive regression algorithms such as neural networks. Thus, this extrapolation methodology represents a useful tool for performing tasks such as high-throughput screening of physical properties, optimising force field parameters, exploring equilibrium phase behaviour, and enabling theory-guided data science for these systems.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2014

The potential benefits of nicaraven to protect against radiation-induced injury in hematopoietic stem/progenitor cells with relative low dose exposures

Highlights: • Nicaraven mitigated the radiation-induced reduction of c-kit{sup +} stem cells. • Nicaraven enhanced the function of hematopoietic stem/progenitor cells. • Complex mechanisms involved in the protection of nicaraven to radiation injury. - Abstract: Nicaraven, a hydroxyl radical-specific scavenger has been demonstrated to attenuate radiation injury in hematopoietic stem cells with 5 Gy γ-ray exposures. We explored the effect and related mechanisms of nicaraven for protecting radiation injury induced by sequential exposures to a relatively lower dose γ-ray. C57BL/6 mice were given nicaraven or placebo within 30 min before exposure to 50 mGy γ-ray daily for 30 days in sequences (cumulative dose of 1.5 Gy). Mice were victimized 24 h after the last radiation exposure, and the number, function and oxidative stress of hematopoietic stem cells were quantitatively estimated. We also compared the gene expression in these purified stem cells from mice received nicaraven and placebo treatment. Nicaraven increased the number of c-kit{sup +} stem/progenitor cells in bone marrow and peripheral blood, with a recovery rate around 60–90% of age-matched non-irradiated healthy mice. The potency of colony forming from hematopoietic stem/progenitor cells as indicator of function was completely protected with nicaraven treatment. Furthermore, nicaraven treatment changed the expression of many genes associated to DNA repair, inflammatory response, and immunomodulation in c-kit{sup +} stem/progenitor cells. Nicaraven effectively protected against damages of hematopoietic stem/progenitor cells induced by sequential exposures to a relatively low dose radiation, via complex mechanisms.

60 APPLIED LIFE SCIENCES↗

DOE OSTI2015

POPs in free-ranging pilot whales, sperm whales and fin whales from the Mediterranean Sea: Influence of biological and ecological factors

The pilot whale Globicephala melas, the sperm whale Physeter macrocephalus, and the fin whale Balaenoptera physalus are large cetaceans permanently inhabiting the Mediterranean Sea. These species are subjected to numerous anthropogenic threats such as exposure to high levels of contaminants. Therefore, selected persistent organic pollutants POPs (29 PCBs, 15 organochlorine compounds, 9 PBDEs and 17 PCDD/Fs) were analysed in blubber biopsies of 49 long-finned pilot whales, 61 sperm whales and 70 fin whales sampled in the North Western Mediterranean Sea (NWMS) from 2006 to 2013. Contamination profile and species feeding ecology were then combined through the use of stable isotopes. δ{sup 13}C, δ{sup 15}N values and POPs levels were assessed through IR-MS and GC–MS respectively. To assess the toxic potency of the dioxin-like compounds, the TEQ approach was applied. δ{sup 15}N values were 12.2±1.3‰ for sperm whales, 10.5±0.7‰ for pilot whales and 7.7±0.8‰ in fin whales, positioning sperm whales at higher trophic levels. δ{sup 13}C of the two odontocetes was similar and amounted to −17.3±0.4‰ for sperm whales and −17.8±0.3‰ for pilot whales; whilst fin whales were more depleted (−18.7±0.4‰). This indicates a partial overlap in toothed-whales feeding habitats, while confirms the differences in feeding behaviour of the mysticete. Pilot whales presented higher concentrations than sperm whales for ΣPCBs (38,666±25,731 ng g{sup −1} lw and 22,849±15,566 ng g{sup −1} lw respectively), ΣPBDEs (712±412 ng g{sup −1} lw and 347±173 ng g{sup −1} lw respectively) and ΣDDTs (46,081±37,506 ng g{sup −1} lw and 37,647±38,518 ng g{sup −1} lw respectively). Fin whales presented the lowest values, in accordance with its trophic position (ΣPCBs: 5721±5180 ng g{sup −1} lw, ΣPBDEs: 177±208 ng g{sup −1} lw and ΣDDTs: 6643±5549 ng g{sup −1} lw). Each species was characterized by large inter-individual variations that are more related to sex than trophic level, with males presenting higher contaminant burden than females. The discriminant analysis (DA) confirmed how DDTs and highly chlorinated PCBs were influential in differentiating the three species. Pollutant concentrations of our species were significantly higher than both their Southern Hemisphere and North Atlantic counterparts, possibly due to the particular Mediterranean geomorphology, which influences pollutants distribution and recycle. Dioxin-like PCBs accounted for over 80% of the total TEQ. This study demonstrated (1) an important exposure to pollutants of Mediterranean cetaceans, often surpassing the estimated threshold toxicity value of 17,000 ng g{sup −1} lw for blubber in marine mammals; and (2) how the final pollutant burden in these animals is strongly influenced not only by the trophic position but also by numerous other factors such as sex, age, body size and geographical distribution. - Highlights: • We analysed POPs concentrations in cetaceans from North-western Mediterranean Sea. • We integrated δ{sup 13}C and δ{sup 15}N values to combine trophic position and contamination. • Odontocetes show PCBs level higher than the toxicity threshold of 17 μg g{sup −1} lw. • Trophic position, sex, body size and distribution affect interspecies diversity.

54 ENVIRONMENTAL SCIENCES↗

DOE OSTI2020

Thermal and magnetic evolution of a crystallizing basal magma ocean in Earth's mantle

We present the thermochemical evolution of a downward crystallizing basal magma ocean (BMO) overlying the liquid outer core and probe its capability to dissipate enough power to generate and sustain an early dynamo. Furthermore, a total of 61 out of 112 scenarios for a BMO with imposed, present-day heat flux, Q BMO , values of 15, 18, and 21 TW and radiogenic heat, Q r , values of 4, 8, and 12 TW fully crystallized during the age of the Earth. Most of these models are energetically capable of inducing magnetic activity for the first 1.5 Gyrs, at least, with durations extending to 2.5 Gyrs; with final core-mantle boundary (CMB) temperatures of 4400 ±500 K-well within current best estimates for inferred temperatures. None of the models with Q BMO = 12 TW achieved a fully crystallized state, which may reflect a lower bound on the present-day heat flux across the CMB. BMO-powered dynamos exhibit strong dependence on the partition coefficient of iron into the liquid layer and its associated melting-point depression for a lower mantle composition at near-CMB conditions-parameters which are poorly constrained to date. Nonetheless, we show that a crystallizing BMO is a plausible mechanism to sustain an early magnetic field.

58 GEOSCIENCES↗

DOE OSTI2017

Multicenter Evaluation of Biochemical Relapse–Free Survival Outcomes for Intraoperatively Planned Prostate Brachytherapy Using an Automated Delivery System

Purpose: To report biochemical recurrence in prostate cancer treated with intraoperatively planned low-dose-rate prostate brachytherapy using an automated delivery system (IO-LDRB). Methods and Materials: Between 2003 and 2013, 2608 patients from 3 centers were treated with IO-LDRB as single-modality treatment for low or low-tier intermediate-risk prostate cancer. Databases from the 3 centers have been analyzed. These independent databases were collected prospectively. Patient, tumor, and treatment characteristics were then compared, Kaplan-Meier survival estimates of biochemical relapse–free survival (bRFS) were generated, and the Cox proportional hazards model was used to determine factors predicting for relapse. Results: A total of 2608 patients with a median follow-up of 4.7 (interquartile range, 3.1-6.9) years were analyzed. Median age was 64 (range, 42-84) years. In these patients, median initial prostate-specific antigen was 5.5 ng/mL, 74% were T1, and 26% were T2; 73% were Gleason 6, and 25% Gleason 7. Median percentage of biopsy cores positive was 33%, and median gland volume was 34.2 cm{sup 3}. Eleven percent of patients received hormones for a median of 3.0 months before implantation. Median seed activity was 0.437 mCi, D90 (dose covering 90% of the prostate volume) was 186.7 Gy, and V100 was 99.37%. Biochemical relapse was observed in 124 patients (4.8%), and median time to failure was 4.0 years. Predicted bRFS was 93% at 7 years. On Cox regression bRFS was dependent only on D90 at the time of implantation and prostate-specific antigen density. Conclusions: This study demonstrates that IO-LDRB is an effective treatment option for patients with low and low-tier intermediate-risk prostate cancer. Rates of biochemical relapse remain low several years after treatment. These results compared favorably to published manual preplan technique results.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

DOE OSTI2018

Dual in-aquifer and near surface processes drive arsenic mobilization in Cambodian groundwaters

Millions of people globally, and particularly in South and Southeast Asia, face chronic exposure to arsenic from reducing groundwaters in which. Arsenic release to is widely attributed largely to reductive dissolution of arsenic-bearing iron minerals, driven by metal reducing bacteria using bioavailable organic matter as an electron donor. However, the nature of the organic matter implicated in arsenic mobilization, and the location within the subsurface where these processes occur, remains debated. In a high resolution study of a largely pristine, shallow aquifer in Kandal Province, Cambodia, we have used a complementary suite of geochemical tracers (including 14 C, 3 H, 3 He, 4 He, Ne, δ 18 O, δD, CFCs and SF 6 ) to study the evolution in arsenic-prone shallow reducing groundwaters along dominant flow paths. The observation of widespread apparent 3 H- 3 He ages of <55years fundamentally challenges some previous models which concluded that groundwater residence times were on the order of hundreds of years. Surface-derived organic matter is transported to depths of >30m, and the relationships between age-related tracers and arsenic suggest that this surface-derived organic matter is likely to contribute to in-aquifer arsenic mobilization. A strong relationship between 3 H- 3 He age and depth suggests the dominance of a vertical hydrological control with an overall vertical flow velocity of ~0.4±0.1m·yr-1 across the field area. A calculated overall groundwater arsenic accumulation rate of ~0.08±0.03μM·yr -1 is broadly comparable to previous estimates from other researchers for similar reducing aquifers in Bangladesh. Although apparent arsenic groundwater accumulation rates varied significantly with site (e.g. between sand versus clay dominated sequences), rates are generally highest near the surface, perhaps reflecting the proximity to the redox cline and/or depth-dependent characteristics of the OM pool, and confounded by localized processes such as continued in-aquifer mobilization, sorption/desorption, and methanogenesis.

54 ENVIRONMENTAL SCIENCES↗

DOE OSTI2018

Landscape‐scale lidar analysis of aboveground biomass distribution in secondary Brazilian Atlantic Forest

Abstract Secondary forests account for more than half of tropical forests and represent a growing carbon sink, but rates of biomass accumulation vary by a factor of two or more even among plots in the same landscape. To better understand the drivers of this variability, we used airborne lidar to measure forest canopy height and estimate biomass over 4529 ha at Serra do Conduru Park in Southern Bahia, Brazil. We measured trees in 30 georeferenced field plots (0.25‐ha each) to estimate biomass using allometry. Then we estimated aboveground biomass density ( ABD ) across the lidar study area using a statistical model developed from our field plots. This model related the 95th percentile of the distribution of lidar return heights to ABD . We overlaid this map of ABD on a Landsat‐derived forest age map to determine rates of biomass accumulation. We found rapid initial biomass regeneration (~6 Mg/ha yr), which slowed as forests aged. We also observed high variability in both height and biomass across the landscape within forests of similar age. Nevertheless, a regression model that accounted for spatial autocorrelation and included forest age, slope, and distance to roads or open areas explained 62 and 77 percent of the landscape variation in ABD and canopy height, respectively. Thus, while there is high spatial heterogeneity in forest recovery, and the drivers of this heterogeneity warrant further investigation, we suggest that a relatively simple set of predictor variables is sufficient to explain the majority of variance in both height and ABD in this landscape.

Becknell, Justin M.↗

DOE OSTI2026

Diagnostics, Prognostics, and Optimization for Lithium-Ion Battery Systems

Health management of lithium-ion battery systems presents a host of challenges due to their complex physics, large numbers of components, and a wide variety of degradation behaviors across different battery types. Dr. Paul Gasper will present on research from the Electrochemical Energy Storage Group on Lithium-ion battery diagnostics, prognostics, and optimization. Diagnostics research, including state-estimation via machine-learning from electrochemical impedance spectroscopy and DC pulses as well as continuous state-estimation via Kalman filters, will highlight the ongoing challenges for accurately measuring the state of batteries without performing time-consuming characterization tests. NLR's industry-recognized battery prognostics work, which predicts real-world battery degradation by identifying degradation rate models from accelerated aging data using statistical modeling and machine-learning, will be used to demonstrate the critical impact of battery controls, thermal management, and operating strategy on durability and lifetime. Finally, the use of prognostic models for financial or lifetime optimization will be discussed.

25 ENERGY STORAGE↗

DOE OSTI2022

An Evolutionary Algorithm to Personalize Stool-Based Colorectal Cancer Screening

Fecal immunochemical testing (FIT) is an established method for colorectal cancer (CRC) screening. Measured FIT-concentrations are associated with both present and future risk of CRC, and may be used for personalized screening. However, evaluation of personalized screening is computationally challenging. In this study, a broadly applicable algorithm is presented to efficiently optimize personalized screening policies that prescribe screening intervals and FIT-cutoffs, based on age and FIT-history. We present a mathematical framework for personalized screening policies and a bi-objective evolutionary algorithm that identifies policies with minimal costs and maximal health benefits. The algorithm is combined with an established microsimulation model (MISCAN-Colon), to accurately estimate the costs and benefits of generated policies, without restrictive Markov assumptions. The performance of the algorithm is demonstrated in three experiments. In Experiment 1, a relatively small benchmark problem, the optimal policies were known. The algorithm approached the maximum feasible benefits with a relative difference of 0.007%. Experiment 2 optimized both intervals and cutoffs, Experiment 3 optimized cutoffs only. Optimal policies in both experiments are unknown. Compared to policies recently evaluated for the USPSTF, personalized screening increased health benefits up to 14 and 4.3%, for Experiments 2 and 3, respectively, without adding costs. Generated policies have several features concordant with current screening recommendations. The method presented in this paper is flexible and capable of optimizing personalized screening policies evaluated with computationally-intensive but established simulation models. It can be used to inform screening policies for CRC or other diseases. For CRC, more debate is needed on what features a policy needs to exhibit to make it suitable for implementation in practice.

60 APPLIED LIFE SCIENCES↗

NASA NTRS1993

Evolutionary implications of a steady-state water abundance on Venus

In 1987, Grinspoon proposed that the data on hydrogen abundance, isotopic composition, and escape rate were consistent with the hypothesis that water on Venus might be in steady-state rather than monotonic decline since the dawn of time. This conclusion was partially based on a derived water lifetime against nonthermal escape of approximately 10(exp 8) years. Others have questioned this conclusion. De Bergh et al. found H2O lifetimes of greater than 10(exp 9) years. Donahue and Hodges derived H2O lifetimes of 0.4 - 5 x 10(exp 9) years. The most sophisticated analysis to date of near-IR radiation from Venus' nightside reveals a water mixing ratio of approximately 30 ppm. Recent re-analysis of Pioneer Venus Mass Spectrometer Data are consistent with a water abundance of 30 ppm. Hodges and Tinsley found an escape flux due to charge exchange with hot H(+) of 2.8 x 10(exp 7) cm(exp -2) s(exp -1). Gurwell and Yung estimated an escape flux of 3.5 x 10(exp 6) cm(exp -2) s(exp -1) from collisions with hot O produced by dissociative recombination of O2(+). Brace et al. estimated an escape flux of 5 x 10(exp 6) cm(exp -2) s(exp -1) from ion escape from the ionotail of Venus. The combined estimated escape flux from all of these processes is 3.7 x 10(exp 7) cm(exp -2) s(exp -1), suggesting a lifetime against escape for water of less than 10(exp 8) years. A recent estimate of H escape flux employing a different ionospheric model and using Pioneer Venus reentry data to estimate the response of the escape flux to the solar cycle finds a somewhat lower escape flux of 1.4 x 10(exp 7) cm(exp -2) s(exp -1), suggesting a water lifetime closer to 2 x 10(exp 8) years, significantly less than the age of the planet. Large uncertainties remain in these quantities, yet the data suggest that a source of water more recent than primordial sources is required and that a steady-state is likely. To obvious candidates for this source water are cometary impact and volcanic outgassing. Other aspects of this investigation are discussed.

Grinspoon, David H.↗

NASA NTRS1995

A molecular line study of NGC 1333/IRAS 4

Molecular line surveys and fully sampled spectral line maps at 1.3 and 0.87 mm are used to examine the physical and chemical characteristics of the extreme Class I sources IRAS 4A and 4B in the L1450/NGC 1333 molecular cloud complex. A very well collimated, jetlike molecular flow emanates from IRAS 4A, with a dynamical age of a few thousand years. Symmetric, clumpy structure along the outflow lobes suggests that there is considerable variability in the mass-loss rate or wind velocity even at this young age. Molecular emission lines toward IRAS 4A and 4B are observed to be weak in the velocity range corresponding to quiescent material surrounding the young stellar objects (YSOs). Depletion factors of 10-20 are observed for all molecules, including CO, even for very conservative mass estimates from the measured millimeter and submillimeter dust continuum. However, abundance scaled with respect to CO are similar to other dark molecular cloud cores. Such depletions could be mimicked by high dust and optical depths or increased grain emissivities at the observing frequencies of 230 and 435 GHz, but the millimeter and submillimeter spectral energy distributions suggest that this is unlikely over the single-dish size scales of 5000-10,000 AU. Dense, outflowing gas is found to be kinematically, but not spatially, distinct from the quiescent material on these size scales. If CO is used as a chemical standard for the high-velocity gas, we find substantial enhancements in abundances of several molecules in outflowing material, most notably CS, SIO, and CH3OH. The SiO emission is kinematically well displaced from the bulk cloud velocity and likely arises from directly shocked material. As is the case for CO, however, the outflow features from more volatile species are centered near the cloud velocity and are often characterized by quite low rotational temperatures. We suggest that grain-grain collisions induced by velocity shear zones surrounding the outflow axes transiently desorb the grain mantles, resulting in large abundance enhancements of selected species. Similar results have recently been obtained in several other low-mass YSOs, where outflowing gas is often both kinematically and spatailly distinct, and are illustrative of the ability of accretion and outflow processes to simultaneously modify the composition of the gas and dust surrounding young stars.

Blake, Geoffrey A.↗

NASA NTRSDate not supplied

Controlled Rest: Investigating the Use of an In-Flight Sleepiness Countermeasure

INTRODUCTION: Sleepiness is commonly reported amongst commercial airline pilots and is recognized as a safety risk due to its impact on performance. Controlled Rest (CR) refers to a short, voluntary nap opportunity taken by pilots on the flight deck as a countermeasure to unanticipated sleepiness in flight. This study explores the profile of CR use in a long-haul commercial airline. METHODS: Forty-four pilots filled in an application-based sleep/work diary and wore actiwatches for approximately 2 weeks. Complete data sets from 239 flights including sleep diaries, actigraphy, and schedules were merged and analyzed. Sleep diary entries were used to set CR intervals in the actigraphy software, which was then used to predict sleep within these intervals. All time-stamps of sleep periods and flight schedules were adjusted for home-base time of the pilots. Pearson Correlations were used to assess the influence of pilot demographics on CR use. A mixed-effects logistic regression was used to analyze the impact of schedule factors on CR. RESULTS: Pilots reported taking CR on 46% (n=110) of observed flights. Average CR attempt duration was 43.1 ± 11.0 minutes. Eighty-percent (n=106/133) of all CR attempts were estimated by actigraphy to have successfully achieved sleep with an average sleep duration during successful rest periods of 31.7 ± 12.2 minutes. Captains reported taking CR on 38% of flights (n=39/102), compared to First Officers reporting 52% (n=71/137) of flights with CR (p=0.131). Age, experience, BMI, and sleep need were not associated with the percentage of flights with CR (all p>0.244). The following schedule factors were associated with a higher frequency of CR: night (55%, n=76) vs. day flights (34%, n=34); <10h (63%, n=80) vs. >10h duration flights (27%, n=30); return (60%, n=71) vs. outbound flights (33%, n=39); and 2-pilot (69%, n=83) vs. >2-pilot flights (23%, n=27) (all p≤0.001). There was a trend for more CR on eastbound flights, but this was not significant (eastbound: 51%, n= 57; westbound: 40%, n= 44; p=0.059). Of note, 22% (n=26) of augmented flights (>2-pilots) contained both CR and Bunk Rest (in a designated rest facility). DISCUSSION: Data from this airline show that pilots commonly use CR to mitigate sleepiness in-flight, especially on flights <10h duration and during home-base nighttime flights. Future studies are required to determine generalizability of these results to other airlines.

sleepiness↗

NASA NTRS2024

Microstructural Evolution of the Civet Cat Norite (72255)

The ‘Civet Cat Norite’ is a ~ 2.5 cm clast within the Apollo impact melt breccia sample 72255 collected during Apollo 17 EVA 2 at Boulder 1. The norite is primarily composed of plagioclase and orthopyroxene with fine-scale exsolution lamellae of augite. The plagioclase and orthopyroxene (OPX) coexist with minor quartz and augitic clinopyroxene (CPX), and accessory apatite, baddeleyite, chromite, ilmenite, loveringite, merrillite, rutile and zircon. The major minerals range from 1 to 4 mm in size and show a cataclastic texture indicated by banding of the light and dark phases]. The chemical composition of the orthopyroxene, augitic exsolution lamellae, and exsolved oxides suggest the norite crystallized in the lower crust of the Moon (10 – 70 km depth) and was subsequently excavated by impact(s). Shock pressure estimates for the norite range from 15 – 35 GPa based on maskeleynite formation within the plagioclase, kink banding in pyroxenes, and granular recrystallization in the accessory phosphates. Previous Rb-Sr and 40 Ar/ 39 Ar analyses recalculated with modern decay constants yield relatively young ages of 4.16 ± 0.05 Ga and 3.99 ± 0.03 Ga, respectively. However, recent U-Pb analyses of some zircon grains from within the Civet Cat yield an age of 4.45 ± 0.03 Ga. While this is the oldest age for any rock recovered from the Moon, the full age spread of zircon from the Civet Cat range from ca. 4.46 to 4.02 Ga, indicating variable Pb-loss and complicating interpretation of the primary age. Recent atom probe analyses indicate minimal Pb mobilization within the oldest zircon grain from Civet Cat, supporting the interpretation that these ancient zircon ages reflect the age of the norite, rather than an apparent antiquity caused by reverse discordance. To investigate the potential antiquity and deep crustal origin of the Civet Cat norite, we have undertaken high resolution microstructural analyses of the major, minor, and accessory minerals to characterize the primary igneous textures and secondary overprinting by impact and metamorphism. The employed analytical techniques include scanning electron microscope-based electron backscatter diffraction (EBSD) analyses, electron probe microanalyzer (EPMA) chemical analyses, and transmission electron microscopy (TEM) of pyroxene, plagioclase, quartz, zircon, and phosphates.

T M Erickson↗

DOE OSTI2026

Modeling Multi-View Impedance-Based Cross-Geometry SOH Estimator for Li-ion Batteries

Abstract: Accurately estimating battery’s State of Health (SOH) remains challenging when models must generalize across cell designs and operating conditions. Most Electrochemical Impedance Spectroscopy (EIS)-based approaches either (i) hand-engineer a few Nyquist-plot features for shallow models—fast but does not generalize across geometries—or (ii) learn directly from Nyquist plots with deep networks, which removes manual feature extraction, yet still limited to a single plot type. As a result, cross-geometry robustness and deployability on constrained Internet of Things (IoT) devices remain open problems. We propose a compact Convolutional Neural Network (CNN) (∼ 10k parameters) that takes multi-representation EIS inputs—Nyquist (real/imaginary) and phase–magnitude (|Z|/ϕ) stacked as four channels, so the model can learn complementary degradation signatures while remaining small enough for fast inference. We build a dataset from cyclic aging of two geometries (LG INR18650MJ1 cylindrical cells and LIR2032 coin cells), acquire EIS every ten cycles from 10 kHz to 10 mHz (10 points/decade), and evaluate with leave-one-cell-out testing strategy. We further study fusion vs. single-representation inputs and assess feasibility for on-device deployment (e.g., NVIDIA Jetson device). The results show that training on multiple EIS representations improves SOH estimation accuracy and cross-geometry generalization compared to single-representation models, which uses only Nyquist or phase–magnitude plots. This design targets accurate, generalizable SOH prediction without manual feature engineering while enabling practical real-time use.

Bakr, Ahmed [The University of Alabama (UA)]↗

DOE OSTI2014

Heliospheric influence on the anisotropy of TeV cosmic rays

This paper provides a theory of using Liouville's theorem to map the anisotropy of TeV cosmic rays seen at Earth using the particle distribution function in the local interstellar medium (LISM). The ultimate source of cosmic ray anisotropy is the energy, pitch angle, and spatial dependence of the cosmic ray distribution function in the LISM. Because young nearby cosmic ray sources can make a special contribution to the cosmic ray anisotropy, the anisotropy depends on the source age, distance and magnetic connection, and particle diffusion of these cosmic rays, all of which make the anisotropy sensitive to the particle energy. When mapped through the magnetic and electric field of a magnetohydrodynamic model heliosphere, the large-scale dipolar and bidirectional interstellar anisotropy patterns become distorted if they are seen from Earth, resulting in many small structures in the observations. Best fits to cosmic ray anisotropy measurements have allowed us to estimate the particle density gradient and pitch angle anisotropies in the LISM. It is found that the heliotail, hydrogen deflection plane, and the plane perpendicular to the LISM magnetic field play a special role in distorting cosmic ray anisotropy. These features can lead to an accurate determination of the LISM magnetic field direction and polarity. The effects of solar cycle variation, the Sun's coronal magnetic field, and turbulence in the LISM and heliospheric magnetic fields are minor but clearly visible at a level roughly equal to a fraction of the overall anisotropy amplitude. The heliospheric influence becomes stronger at lower energies. Below 1 TeV, the anisotropy is dominated by small-scale patterns produced by disturbances in the heliosphere.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2015

Radiation Therapy Planning for Early-Stage Hodgkin Lymphoma: Experience of the International Lymphoma Radiation Oncology Group

Purpose: Early-stage Hodgkin lymphoma (HL) is a rare disease, and the location of lymphoma varies considerably between patients. Here, we evaluate the variability of radiation therapy (RT) plans among 5 International Lymphoma Radiation Oncology Group (ILROG) centers with regard to beam arrangements, planning parameters, and estimated doses to the critical organs at risk (OARs). Methods: Ten patients with stage I-II classic HL with masses of different sizes and locations were selected. On the basis of the clinical information, 5 ILROG centers were asked to create RT plans to a prescribed dose of 30.6 Gy. A postchemotherapy computed tomography scan with precontoured clinical target volume (CTV) and OARs was provided for each patient. The treatment technique and planning methods were chosen according to each center's best practice in 2013. Results: Seven patients had mediastinal disease, 2 had axillary disease, and 1 had disease in the neck only. The median age at diagnosis was 34 years (range, 21-74 years), and 5 patients were male. Of the resulting 50 treatment plans, 15 were planned with volumetric modulated arc therapy (1-4 arcs), 16 with intensity modulated RT (3-9 fields), and 19 with 3-dimensional conformal RT (2-4 fields). The variations in CTV-to-planning target volume margins (5-15 mm), maximum tolerated dose (31.4-40 Gy), and plan conformity (conformity index 0-3.6) were significant. However, estimated doses to OARs were comparable between centers for each patient. Conclusions: RT planning for HL is challenging because of the heterogeneity in size and location of disease and, additionally, to the variation in choice of treatment techniques and field arrangements. Adopting ILROG guidelines and implementing universal dose objectives could further standardize treatment techniques and contribute to lowering the dose to the surrounding OARs.

62 RADIOLOGY AND NUCLEAR MEDICINE↗