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At least 1,531 records · Page 85

SU-E-T-253: Development of a GDPM Monte Carlo Based Quality Assurance Tool for Cyberknife

Purpose: To develop a 3D quality assurance (QA) tool for Cyberknife plans using a GPU-based Monte Carlo dose calculation package, gDPM. The developed QA tool will be used as a secondary check for Cyberknife treatment planning software (TPS) reported dose distributions. Methods: Phase space files of the 5, 7.5, 10, 15, and 60 mm iris cones were downloaded from IAEA phase-space database. From the 60mm iris cone phase space file, we were able to generate raw phase space files for all other cones using a particle rejection method. The particles in the raw phase space files were binned with respect to the radial position and energy for commissioning. During the commissioning process, gDPM calculated percent depth dose and off-center ratios which were compared to those measured in the Blue Phantom. The off-axis data was measured with an SAD setup at depths of 15, 50, 100, 200, and 300 mm. At the commissioning stage, an optimization problem was solved to adjust the binned particles weights to minimize the difference between the calculated and measured ones. Commissioning validations will be performed by measuring point dose data of patient specific plans delivered to water phantoms. With commissioned phase space files, 3D patient-specific dose distributions will be calculated and compared against TPS reported dose. Results: Beyond the initial buildup region, the root mean square difference between the calculated and measured percent depth dose differences was less than 0.5%. The full-width half-max data from the off-axis ratio calculations was found to be within 0.1 mm of the measured data. Conclusion: Our current work showed excellent agreement between the gDPM calculated dose and the measured data for all cone sizes and types for the Cyberknife system. Implementation of a fast and accurate QA tool for patient specific plans will be feasible with this tool.

60 APPLIED LIFE SCIENCES↗

Spectral and Microclimate Measurements in Relation to Gold-Standard Methods Field Campaign Report

Arable is an agricultural data and analytics company offering an Internet of things (IOT)-enabled irrigation management tool, weather station, and crop monitor: the Arable Mark. The device synthesizes both climate and plant data to produce actionable insights on natural resource management, mainly commercial agriculture at any scale. Arable collected 11 months of microclimate and radiometric data at the U.S. Department of Energy’s Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) observatory to compare measurements of the Arable Mark to the ARM-SGP gold-standard sensors, and for demonstrating the ease of installation and system value to stakeholders. A member from Arable labs installed the device on January 10, 2018, at the ARM facilities and the site managers were in charge of maintaining the sensors in a clean state until the unit’s removal on January 15, 2019. The sampling was positively uneventful, except for a period during the winter when the device stopped posting data for about one week. The verdict was that the equipment required an external solar panel to stay powered through the shorter days of winter. A solar panel was shipped to the SGP, and the unit came back to full charge to continue sending data for the rest of the sampling period. The main goal of the project is to use the data collected by the Arable Mark and build a model that can establish a close relationship with the current methodologies applied to measure ecosystem response to environmental changes. During the sampling period, our team discovered that there was a drift in some of the meteorological data and also in the radiometry, so all efforts are focused into the development of models that would reduce the errors in the reported values.

Southern Great Plains, evapotranspiration, photosy↗

TU-EF-304-03: 4D Monte Carlo Robustness Test for Proton Therapy

Purpose: Breathing motion and approximate dose calculation engines may increase proton range uncertainties. We address these two issues using a comprehensive 4D robustness evaluation tool based on an efficient Monte Carlo (MC) engine, which can simulate breathing with no significant increase in computation time. Methods: To assess the robustness of the treatment plan, multiple scenarios of uncertainties are simulated, taking into account the systematic and random setup errors, range uncertainties, and organ motion. Our fast MC dose engine, called MCsquare, implements optimized models on a massively-parallel computation architecture and allows us to accurately simulate a scenario in less than one minute. The deviations of the uncertainty scenarios are then reported on a DVH-band and compared to the nominal plan.The robustness evaluation tool is illustrated in a lung case by comparing three 60Gy treatment plans. First, a plan is optimized on a PTV obtained by extending the CTV with an 8mm margin, in order to take into account systematic geometrical uncertainties, like in our current practice in radiotherapy. No specific strategy is employed to correct for tumor and organ motions. The second plan involves a PTV generated from the ITV, which encompasses the tumor volume in all breathing phases. The last plan results from robust optimization performed on the ITV, with robustness parameters of 3% for tissue density and 8 mm for positioning errors. Results: The robustness test revealed that the first two plans could not properly cover the target in the presence of uncertainties. CTV-coverage (D95) in the three plans ranged respectively between 39.4–55.5Gy, 50.2–57.5Gy, and 55.1–58.6Gy. Conclusion: A realistic robustness verification tool based on a fast MC dose engine has been developed. This test is essential to assess the quality of proton therapy plan and very useful to study various planning strategies for mobile tumors. This work is partly funded by IBA (Louvain-la-Neuve, Belgium)

60 APPLIED LIFE SCIENCES↗

High-Alpha Research Vehicle Lateral-Directional Control Law Description, Analyses, and Simulation Results

This report contains a description of a lateral-directional control law designed for the NASA High-Alpha Research Vehicle (HARV). The HARV is a F/A-18 aircraft modified to include a research flight computer, spin chute, and thrust-vectoring in the pitch and yaw axes. Two separate design tools, CRAFT and Pseudo Controls, were integrated to synthesize the lateral-directional control law. This report contains a description of the lateral-directional control law, analyses, and nonlinear simulation (batch and piloted) results. Linear analysis results include closed-loop eigenvalues, stability margins, robustness to changes in various plant parameters, and servo-elastic frequency responses. Step time responses from nonlinear batch simulation are presented and compared to design guidelines. Piloted simulation task scenarios, task guidelines, and pilot subjective ratings for the various maneuvers are discussed. Linear analysis shows that the control law meets the stability margin guidelines and is robust to stability and control parameter changes. Nonlinear batch simulation analysis shows the control law exhibits good performance and meets most of the design guidelines over the entire range of angle-of-attack. This control law (designated NASA-1A) was flight tested during the Summer of 1994 at NASA Dryden Flight Research Center.

Davidson, John B.↗

Epi Archive: automated data collection of notifiable disease data

LANL has built a software program that automatically collects global notifiable disease data—particularly data stored in files—and makes it available and shareable within the Biosurveillance Ecosystem(BSVE) as a new data source. This will improve the prediction and early warning of disease events and other applications. Most countries do not report national notifiable disease data in a machine-readable format. Data are often in the form of a file that contains text, tables and graphs summarizing weekly or monthly disease counts. This presents a problem when information is needed for more data intensive approaches to epidemiology, biosurveillance and public health as exemplified by the Biosurveillance Ecosystem(BSVE).While most nations do likely store their data in a machine-readable format, the governments are often hesitant to share data openly for a variety of reasons that include technical, political, economic, and motivational issues. For example, an attempt by LANL to obtain a weekly version of openly available monthly data, reported by the Australian government, resulted in an onerous bureaucratic reply. The obstacles to obtaining data included: paperwork to request data from each of the Australian states and territories, a long delay to obtain data (up to 3 months) and extensive limitations on the data’s use that prohibit collaboration and sharing. This type of experience when attempting to contact public health departments or ministries of health for data is not uncommon. A survey conducted by LANL of notifiable disease data reporting in 52 countries identified only 10 as being machine-readable and 42 being reported in pdf files on a regular basis. Within the 42 nations that report in pdf files, 32 report in a structured, tabular format and10 in a non-structured way. As a result, LANL has developed a tool-Epi Archive (formerly known as EPIC)-to automatically and continuously collect global notifiable disease data and make it readily accessible. We conducted a survey of the national notifiable disease reporting systems notating how the data is reported in two important dimensions: date standards and case definitions. The development of software to regularly ingests notifiable disease data frand makes this data available involved four main steps scraping, extracting, parsing and persisting. For scraping: we would examine website designs and determine reporting mechanisms for each country/website as well as what varies across the reporting mechanisms. We then designed and wrote code to automate the downloading of report pdf files, for each country. We stored report pdfs along with appropriate metadata for extracting and parsing. For extracting: we developed software that can extract notifiable disease data presented in tabular form from a pdf file. We combined the methodology of figure placement detection with the in-house developed table extraction and annotation heuristics. For parsing: we determined what to extract from each pdf dataset from the survey conducted. We then parsed the extracted data into uniform data structures correctly accommodating the dimensions surveyed and the various human languages. This task involved ingesting notifiable disease data in many disparate formats extracted from pdf files and coalescing the data into a standardized format. For persisting: We then store the data in the Epi Archive PostgreSQL database and make it available through the BSVE. The EpiArchive tool currently contains subnational notifiable disease data from 10 nations. When a user accesses the EpiArchive site, they are prompted with four fields: country, region, disease, and date duration. These fields allow the user to specify the location(down to the state level), the disease of interest, and the duration of interest. Upon form submission, a time series is generated from the users’ specifications. The generated time series can then be downloaded into a csv file if a user is interested in performing personal analysis. Additionally, the data from EpiArchive can be reached through an API. LANL as part of a currently funded DTRA effort so that it will automatically and continuously collect global notifiable disease data—particularly data stored in pdf files—and make it available and shareable within the Biosurveillance Ecosystem (BSVE) as a new data source. This will provide data to analytics and users that will improve the prediction and early warning of disease events and other applications.

59 BASIC BIOLOGICAL SCIENCES↗

Gearbox Reliability Collaborative Phase 3 Gearbox 3 Test Report

Many gearboxes in wind turbines do not achieve their expected design life; they do, however, commonly meet or exceed the design criteria specified in current standards in the gear, bearing, and wind turbine industry as well as third-party certification criteria. The cost of gearbox replacements and rebuilds, as well as the downtime associated with these failures, increases the cost of wind energy. In 2007, the U.S. Department of Energy established the National Renewable Energy Laboratory (NREL) Gearbox Reliability Collaborative (GRC). Its goals are to understand the root causes of premature gearbox failures and to improve their reliability. The GRC is examining a hypothesis that the gap between design-estimated and actual wind turbine gearbox reliability is caused by underestimation of loads, inaccurate design tools, the absence of critical elements in the design process, or insufficient testing. This report describes the recently completed tests of GRC Gearbox 3 in the National Wind Technology Center dynamometer and documents any modifications to the original test plan. In this manner, it serves as a guide for interpreting the publicly released data sets with brief analyses to illustrate the data. The primary test objective was to measure the planetary load-sharing characteristics in the same conditions as the original GRC gearbox design. If the measured load-sharing characteristics are close to the design model, the projected improvement in planetary section fatigue life and the efficacy of preloaded TRBs in mitigating the planetary bearing fatigue failure mode will have been demonstrated. Detailed analysis of that test objective will be presented in subsequent publications.

17 WIND ENERGY↗

Electronic Design Automation: Integrating the Design and Manufacturing Functions

As the complexity of electronic systems grows, the traditional design practice, a sequential process, is replaced by concurrent design methodologies. A major advantage of concurrent design is that the feedback from software and manufacturing engineers can be easily incorporated into the design. The implementation of concurrent engineering methodologies is greatly facilitated by employing the latest Electronic Design Automation (EDA) tools. These tools offer integrated simulation of the electrical, mechanical, and manufacturing functions and support virtual prototyping, rapid prototyping, and hardware-software co-design. This report presents recommendations for enhancing the electronic design and manufacturing capabilities and procedures at JSC based on a concurrent design methodology that employs EDA tools.

Bachnak, Rafic↗

Satellite Systems Design/Simulation Environment: A Systems Approach to Pre-Phase A Design

A toolset for the rapid development of small satellite systems has been created. The objective of this tool is to support the definition of spacecraft mission concepts to satisfy a given set of mission and instrument requirements. The objective of this report is to provide an introduction to understanding and using the SMALLSAT Model. SMALLSAT is a computer-aided Phase A design and technology evaluation tool for small satellites. SMALLSAT enables satellite designers, mission planners, and technology program managers to observe the likely consequences of their decisions in terms of satellite configuration, non-recurring and recurring cost, and mission life cycle costs and availability statistics. It was developed by Princeton Synergetic, Inc. and User Systems, Inc. as a revision of the previous TECHSAT Phase A design tool, which modeled medium-sized Earth observation satellites. Both TECHSAT and SMALLSAT were developed for NASA.

Ferebee, Melvin J., Jr.↗

Efficient Hybrid Attack Graph Generation for Cyber-Physical System Resilience Experimentation (Final Project Report)

HAGEN project has developed theory, algorithms, and capabilities to assist cyber physical system modelers and operators to perform system and device-level vulnerability assessment, risk assessment, impact assessment, and mitigation planning. The project generates hybrid attack graphs for Cyber-Physical System (CPS) resilience experimentation at desired scale and speed. The project will produce composite attack datasets, algorithms, and demonstrable prototypical tools, and a library of high-impact attack sequences for a given CPS of interest. This report provided overall summary of research and development performed between FY22-24.

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEF↗

Potential Impacts of Accelerated Climate Change (Second Annual Report of Work)

This study is part of the U.S. Nuclear Regulatory Commission’s (NRC) Probabilistic Flood Hazard Assessment (PFHA) research plan that aims to develop regulatory tools and guidance to support and enhance the NRC’s capacity to perform thorough and efficient reviews of license applications and license amendment requests. In Year 1, Pacific Northwest National Laboratory staff prepared an annual report that summarized recent scientific findings on climate change, with a particular focus on climatic elements that are relevant to NRC concerns on a regional level (i.e., increasing air and water temperatures, decreasing water availability, increasing frequency and intensity of storms and flooding, and sea-level rise). This report summarizes Year 2 activities, which focused on reviewing scientific findings regarding region-specific climatic extremes for the southeastern United States. According to the U.S. Global Change Research Program Third National Climate Assessment, the U.S. Southeast Region consists of 11 southeastern states, Puerto Rico, and the Virgin Islands. Except for Kentucky, Puerto Rico, and the Virgin Islands, all included states have operating nuclear power plants. Further, new nuclear power reactor permit and license applications have been submitted to the NRC in the recent past for sites located in several southeastern states. Therefore, having an improved understanding of potential climate changes and their hydrologic impacts in the Southeast Region is important to inform the PFHA research plan. Climatic features relevant to the NRC for the Southeast Region include high temperature extremes, precipitation extremes, flooding, high winds associated with tropical cyclones and tornadoes, sea-level rise, and storm surge and associated inland inundation. Drawing primarily from the climate assessment reports and peer-reviewed literature, this Year 2 annual report summarizes the observed climate, its past changes, and its projected changes, as well as 21st century hydrologic impacts in the Southeast Region. Despite the relatively mild changes observed in the past and projected in the future for the mean climate of the Southeast Region, many aspects of climatic extremes such as extreme precipitation have exhibited changes in the last century. In addition, climate and hydrologic models project further changes in the future. Pacific Northwest National Laboratory staff presented updates summarizing these findings at the Second Annual PFHA Research Workshop, which took place from January 23 to 25, 2017, at NRC Headquarters in Rockville, Maryland.

54 ENVIRONMENTAL SCIENCES↗

Another Approach to Enhance Airline Safety: Using Management Safety Tools

The ultimate goal of conducting an accident investigation is to prevent similar accidents from happening again and to make operations safer system-wide. Based on the findings extracted from the investigation, the "lesson learned" becomes a genuine part of the safety database making risk management available to safety analysts. The airline industry is no exception. In the US, the FAA has advocated the usage of the System Safety concept in enhancing safety since 2000. Yet, in today s usage of System Safety, the airline industry mainly focuses on risk management, which is a reactive process of the System Safety discipline. In order to extend the merit of System Safety and to prevent accidents beforehand, a specific System Safety tool needs to be applied; so a model of hazard prediction can be formed. To do so, the authors initiated this study by reviewing 189 final accident reports from the National Transportation Safety Board (NTSB) covering FAR Part 121 scheduled operations. The discovered accident causes (direct hazards) were categorized into 10 groups Flight Operations, Ground Crew, Turbulence, Maintenance, Foreign Object Damage (FOD), Flight Attendant, Air Traffic Control, Manufacturer, Passenger, and Federal Aviation Administration. These direct hazards were associated with 36 root factors prepared for an error-elimination model using Fault Tree Analysis (FTA), a leading tool for System Safety experts. An FTA block-diagram model was created, followed by a probability simulation of accidents. Five case studies and reports were provided in order to fully demonstrate the usefulness of System Safety tools in promoting airline safety.

Lu, Chien-tsug↗

Comparison Tools for Assessing the Microgravity Environment of Missions, Carriers and Conditions

The Principal Component Spectral Analysis and the Quasi-steady Three-dimensional Histogram techniques provide the means to describe the microgravity acceleration environment of an entire mission on a single plot. This allows a straight forward comparison of the microgravity environment between missions, carriers, and conditions. As shown in this report, the PCSA and QTH techniques bring both the range and median of the microgravity environment onto a single page for an entire mission or another time period or condition of interest. These single pages may then be used to compare similar analyses of other missions, time periods or conditions. The PCSA plot is based on the frequency distribution of the vibrational energy and is normally used for an acceleration data set containing frequencies above the lowest natural frequencies of the vehicle. The QTH plot is based on the direction and magnitude of the acceleration and is normally used for acceleration data sets with frequency content less than 0.1 Hz. Various operating conditions are made evident by using PCSA and QTH plots. Equipment operating either full or part time with sufficient magnitude to be considered a disturbance is very evident as well as equipment contributing to the background acceleration environment. A source's magnitude and/or frequency variability is also evident by the source's appearance on a PCSA plot. The PCSA and QTH techniques are valuable tools for extracting useful information from acceleration data taken over large spans of time. This report shows that these techniques provide a tool for comparison between different sets of microgravity acceleration data, for example different missions, different activities within a mission, and/or different attitudes within a mission. These techniques, as well as others, may be employed in order to derive useful information from acceleration data.

DeLombard, Richard↗

Report of the Atmosphere to Electrons Land-Based Mesoscale-to-Microscale Coupling Project (FY2020)

The overall goal of the Mesoscale-to-Microscale Coupling (MMC) project is to improve coupling between mesoscale and microscale simulations via improved guidance and new strategies for setting up simulations and for the development of new tools that can be used across the community. Including the mesoscale forcing is critical to modeling the full energy transfer across scales in the atmosphere. The project-specific objectives include: 1) To apply rigorous verification and validation (V&V) techniques to the new modeling tools that are developed as part of the project to ensure the accuracy of our codes and results and to develop estimates of the relative uncertainty. 2) To improve computational performance of the coupled MMC models through the development of methods that can be used to reduce turbulence spin-up time and hence the size of computational domains. 3) To improve representation of the surface layer in microscale models to enhance simulations of hub-height wind speed. 4) To develop guidance for the community describing the best ways to couple mesoscale and microscale models, including specific spatial scales at which the handoff to the microscale model should occur. 5) To prepare documentation and a suite of software tools that can be used across the community. And 6) To transition MMC research to the offshore environment. Major progress was made in each of these areas during FY20. The land-based portion of the project is reported herein, while the offshore portion will be reported separately. The team continued to advance the MMC tools and methodologies as well as to document their performance in journal papers and conference presentations, although several planned conferences were cancelled due to the COVID-19 pandemic.

54 ENVIRONMENTAL SCIENCES↗

Real-Time Optimization Workflow Status Update

Economically optimal and safe operation of integrated energy systems (IES) requires optimization at many different time scales. A real-time optimization (RTO) workflow will attempt to maximize revenue and minimize operational costs on a time scale of minutes to hours. Such a workflow requires the use of a digital twin (DT), which is a virtual representation of a physical system. The DT is updated using real-time data from the physical system, and serves as a model in an optimization framework. The optimization results are then sent back to the physical system to complete the loop. This report details the progress made in developing building blocks for a DT/RTO framework. The Risk Analysis Virtual Environment (RAVEN) platform within the Framework for Optimization of Resources and Economics (FORCE) tool suite can perform many of the tasks required for building a DT and performing RTO. The first item of this report details RAVEN enhancements that enable RAVEN workflows to be run in various environments. Data communication between the physical system and its DT is essential for successful RTO. This includes preprocessing real-time data, loading data into a data warehouse, and querying the stored data. The second section of this report describes the progress made in implementing an adapter in Python in order for Deep Lynx to handle the data communication. Typical dispatch optimization frameworks are built on linear programming (LP). The prototype RTO workflow developed in this report uses an LP problem as a part of a receding-horizon- or economic model predictive control (EMPC) based optimization. The third section of this report details the framework of an RTO workflow in which the system consists of a simple electrical storage device. A DT can be built from a reduced-order model (ROM). Integrating a ROM into a typical LP optimization framework has been challenging because most optimization packages require the user to write algebraic expressions for the system model. The final section of this report shows how an externally built RAVEN ROM can be integrated in an RTO framework by using the Python package Pyomo. This demonstrates the RTO workflow capability from a software-only perspective and is an important step in demonstrating the capability to implement an RTO workflow for a physical system.

97 MATHEMATICS AND COMPUTING↗

Analysis of Data Fusion Between Waveform Events and Radionuclide Detections Reported in 2021 by the International Data Centre

During this project, we assessed the percentage of events reported by the International Data Centre (IDC) that are candidates for evaluation using data fusion methods. We calculated the percentage of waveform (seismic, hydroacoustic, infrasound, SHI) events that may be associated with radionuclide (RN) detections and vice versa. For this task, data fusion means identifying RN detections that may be associated with SHI events. The task of producing a fused SHI and RN bulletin is included in the IDC operational manual. As of 2022, the production of a fused event bulletin remains incomplete, largely because methods for producing the bulletin are under development. Nonetheless, simple methods for data fusion have been developed and preliminary software tools are available at the IDC to associate SHI events and RN detections. This report is a first look at the percentage of SHI events that may be candidates for fusion with RN detections or bulletins. One year of IDC bulletin data (2021) is considered in this report. It is important to note that there were no known nuclear explosions during this time period. Hence, we expect that events during this time period would generate SHI and RN signals. If many SHI events are candidates for fusion with RN data, greater priority should be placed on establishing screening procedures before and/or during the fusion process. By contrast, if the number of candidate events is diminishingly small, then data fusion is not a driver for further development of event or detection screening at the IDC. LLNL reviewed the events reported in the Standard Event Bulletin (SEB) and determined which events are candidates for fusion with the Reviewed Radionuclide Reports (RRR). Much of the work involves establishing a metric or metrics for determining whether a Reviewed Event Bulletin (REB) event is a candidate for data fusion.

58 GEOSCIENCES↗

MOOSE Reactor Module Meshing Enhancements to Support Reactor Physics Analysis

The U.S. Department of Energy Office of Nuclear Energy Advanced Modeling and Simulation (NEAMS) program develops an integrated suite of advanced reactor physics tools built upon the Multiphysics Object-Oriented Simulation Environment (MOOSE) framework. Each code generally requires an input finite element mesh on which the physics solution is calculated, reported, and transferred to other physics codes. The meshing process is often burdensome for the complex geometries present in reactors due to lack of easy-to-use, open-source meshing tools. To address the bottleneck associated with meshing complex geometries found in nuclear reactors, NEAMS initiated the development of the MOOSE Reactor Module starting in FY21. The Reactor Module builds off the existing MOOSE Mesh System to include targeted meshing capabilities such as the ability to generate hexagonal pin cells, assemblies with ducts, rotating control drums, cores, peripheral zones around a core, as well as the automatic labeling (“reporting IDs”) of pin, assembly, and planar zones to simplify post-processing of results. As a Physics Module in MOOSE, the Reactor Module is open-source, available with any MOOSE installation, directly compatible with MOOSE-based tools, and can be invoked from MOOSEbased applications to generate meshes. Functionality from the Reactor Module has been applied to several advanced reactor concepts to demonstrate user workflow improvements and accuracy. The primary objective of the Reactor Module is to improve useability of MOOSEbased tools by streamlining mesh generation and output inspection processes. During FY22, the functionality of the Reactor Module (and accompanying Mesh System) has been expanded based on user needs. First, the Reactor Geometry Mesh Builder capability developed primarily in FY21 has been refactored and merged to the public MOOSE repository. This capability wraps underlying Reactor Module mesh generators into a “Pin – Assembly – Core” workflow appropriate for conventional Cartesian and hexagonal geometries, and notably assigns material IDs during mesh generation stage and generates only the minimal number of blocks needed in order to reduce computational burden. Biasing and boundary layer options have been added to the base mesh generators as required by thermal hydraulics solvers. The reporting ID functionality has been expanded to differentiate ring-wise and azimuthal sectors within a pin for use with depletion algorithms, and VectorPostProcessor and Reporter objects are now available to integrate solution variables across zones based on ID combinations. Functionality to trim hexagonal meshes along the center or periphery has been developed so users may leverage symmetry and reflective boundary conditions to reduce the mesh size. A flexible and powerful tool to fill the space between two sidesets has been introduced to the framework and can be used for transition layers such as stitching two assemblies together with different numbers of pins, or for complex geometries which do not follow conventional Cartesian/hexagonal patterns. Finally, additional verification problems were performed with NEAMS physics tools in complement with existing NEAMS work.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Integrated Research Infrastructure Architecture Blueprint Activity (Final Report 2023)

The complexity of scientific pursuits is increasing rapidly with aspects that require dynamic integration of experiment, observation, theory, modeling, simulation, visualization, machine learning (ML), artificial intelligence (AI), and analysis. Research projects across the Department of Energy (DOE) are increasingly data and compute intensive. Innovative research teams are accelerating the pace of discovery by using high-performance computational and data tools in their research workflows and leveraging multiple research infrastructures. Additionally, several recent high-level U.S. government reports underscore the necessity of a new advanced computing ecosystem for international competitiveness and national security. International competitors are moving forward with major research infrastructure integration efforts that seek to capture a competitive advantage in the global innovation race. Owing to its unparalleled constellation of world-class experimental and observational facilities and high-performance and extreme-scale computational, data, and networking infrastructure, DOE is positioned to be a global leader in this new era of integrated science. However, this new integration paradigm will demand continuing evolution to ensure the U.S. remains a global leader in research and innovation. The DOE Office of Science (SC) has seized on the strategic importance of integration and has adopted a vision for Integrated Research Infrastructure (IRI): To empower researchers to meld DOE’s world-class research tools, infrastructure, and user facilities seamlessly and securely in novel ways to radically accelerate discovery and innovation. To respond to the evolving computational requirements of research and the competitive international innovation landscape, experimental facilities could be connected with high performance computing resources for near real-time analysis, and resources should be provided for merging enormous and diverse data for AI/ML techniques and analysis.

97 MATHEMATICS AND COMPUTING↗

Meeting report: Ocean ‘omics science, technology and cyberinfrastructure: current challenges and future requirements (August 20-23, 2013)

The National Science Foundation’s EarthCube End User Workshop was held at USC Wrigley Marine Science Center on Catalina Island, California in August 2013. The workshop was designed to explore and characterize the needs and tools available to the community that is focusing on microbial and physical oceanography research with a particular emphasis on ‘omic research. The assembled researchers outlined the existing concerns regarding the vast data resources that are being generated, and how we will deal with these resources as their volume and diversity increases. Particular attention was focused on the tools for handling and analyzing the existing data, on the need for the construction and curation of diverse federated databases, as well as development of shared, interoperable, “big-data capable” analytical tools. The key outputs from this workshop include (i) critical scientific challenges and cyber infrastructure constraints, (ii) the current and future ocean ‘omics science grand challenges and questions, and (iii) data management, analytical and associated and cyber-infrastructure capabilities required to meet critical current and future scientific challenges. The main thrust of the meeting and the outcome of this report is a definition of the ‘omics tools, technologies and infrastructures that facilitate continued advance in ocean science biology, marine biogeochemistry, and biological oceanography.

59 BASIC BIOLOGICAL SCIENCES↗