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At least 1,531 records · Page 85

Diagnostic Cardiac Catheterization Using the MEDRAD Avanta™ Fluid Management System as Compared to the Traditional Manual Injection Method

Nearly 4 million patient procedures performed annually in US cardiac catheterization laboratories utilize contrast media to achieve vessel opacification. The amount of contrast media used is variable and depends on the complexity of the procedure, the method of contrast delivery as well as the skill-level of the operator. Since the total amount of contrast used for each procedure can have both patient safety and economic implications, it is essential for cardiologists to have the ability to control contrast delivery such that optimal angiographic image quality is achieved using the least amount of contrast. Although the complication rate associated with cardiac catheterization remains low, the most common serious complication, contrast-induced nephropathy (CIN), is associated with poor prognosis and a high mortality rate. Numerous interventional strategies for preventing and reducing the severity of CIN have demonstrated varying degrees of clinical benefit, but none has been shown to reliably prevent this serious complication. To date, the most effective approach for reducing the risk of CIN is to properly hydrate the patient and to minimize the amount of contrast media administered. Automated injection systems are intended for use in virtually all cardiac catheterization procedures and have numerous features which can provide potential advantages over traditional methods. With automated injection technology the operator is able to control and precisely monitor contrast delivery. Additionally, the MEDRAD Avanta Fluid Management Injection System utilizes a sterile contrast reservoir which eliminates the need to discard unused contrast in individual opened containers following each procedure. Considering that an average of 50% of opened contrast media is wasted using manual injection methods, this savings can provide a substantial economic benefit. Automated systems also facilitate the use of smaller (5 French) catheter sizes. Precise flow control and the use of smaller diameter catheters have both been shown to reduce the volume of contrast administered. The use of smaller size catheters also permits more rapid hemostasis, thus allowing shorter ambulation time without the need for costly wound closure devices. These factors can result in enhanced patient satisfaction as well as more efficient management of post-procedure rooms. The intent of this study was to demonstrate that using the MEDRAD Avanta™ Fluid Management Injection System (MEDRAD, INC., Pittsburgh, PA) for coronary diagnostic procedures can produce a reduction in the volume of contrast administered without loss of operational quality or efficiency. In addition, this study will explore procedure time and efficiency in an effort to minimize the amount of ionizing radiation delivered to the patient as well as the diagnostic team members. Study Design This is a post-market study designed to collect data during diagnostic cardiac catheterization when utilizing 5FR or 6FR catheters in conjunction with the Avanta Fluid Management System or a manual manifold injection method control group. A minimum of 420 patients scheduled for diagnostic cardiac catheterization will be enrolled in the study cohort. Patients will be assigned into the following two groups. Group 1: Catheterization with 5FR or 6FR catheters, using the traditional manual manifold injection method for contrast media delivery which is defined as manual hand injection of contrast media through a 3 or 4 port manifold and left ventriculography performed via standard fixed rate power injection. Group 2: Catheterization with 5FR or 6FR catheters, using the MEDRAD Avanta™ system for contrast media delivery. Study endpoints include volume of contrast media administered during diagnostic cardiac catheterization, volume of contrast media wasted post-procedure, procedure time (defined as the time from first catheter insertion to last diagnostic catheter removal), fluoroscopy time and angiographic image quality. The study demonstrated that use of the Advanta system reduced overall contrast utilization by decreasing the amount of contrast administered to the patient and reducing the amount of contrast wasted during preparation and post-procedure clean-up. The quality of the angiographic images and the radiation exposure to the patient were not affected.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

The Kelvin-Helmholtz instability of boundary-layer plasmas in the kinetic regime

The dynamics of the Kelvin-Helmholtz instability are investigated in the kinetic, high-frequency regime with a novel, two-dimensional, mesh-free tree code. In contrast to earlier studies which focused on specially prepared equilibrium configurations in order to compare with fluid theory, a more naturally occurring plasma-vacuum boundary layer is considered here with relevance to both space plasma and linear plasma devices. Quantitative comparisons of the linear phase are made between the fluid and kinetic models. After establishing the validity of this technique via comparison to linear theory and conventional particle-in-cell simulation for classical benchmark problems, a quantitative analysis of the more complex magnetized plasma-vacuum layer is presented and discussed. It is found that in this scenario, the finite Larmor orbits of the ions result in significant departures from the effective shear velocity and width underlying the instability growth, leading to generally slower development and stronger nonlinear coupling between fast growing short-wavelength modes and longer wavelengths.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

FATE Unified Modeling Method for Spent Nuclear Fuel and Sludge Processing, Shipping and Storage - 13405

A unified modeling method applicable to the processing, shipping, and storage of spent nuclear fuel and sludge has been incrementally developed, validated, and applied over a period of about 15 years at the US DOE Hanford site. The software, FATE{sup TM}, provides a consistent framework for a wide dynamic range of common DOE and commercial fuel and waste applications. It has been used during the design phase, for safety and licensing calculations, and offers a graded approach to complex modeling problems encountered at DOE facilities and abroad (e.g., Sellafield). FATE has also been used for commercial power plant evaluations including reactor building fire modeling for fire PRA, evaluation of hydrogen release, transport, and flammability for post-Fukushima vulnerability assessment, and drying of commercial oxide fuel. FATE comprises an integrated set of models for fluid flow, aerosol and contamination release, transport, and deposition, thermal response including chemical reactions, and evaluation of fire and explosion hazards. It is one of few software tools that combine both source term and thermal-hydraulic capability. Practical examples are described below, with consideration of appropriate model complexity and validation. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Finite element modeling of electropolishing of radio frequency dipole Nb crab cavity in hydrofluoric-sulfuric acid electrolyte

The superior performance of niobium superconducting radio frequency (SRF) cavities is achieved through meticulous surface treatment, notably via chemical electropolishing, ensuring exceptionally smooth surfaces. While this technique has been extensively employed for cylindrically symmetric structures, addressing more intricate geometries poses significant challenges in achieving uniform polishing and controlled material removal, especially when moving away from retractable cathodes. This presents a multifaceted electrochemical, thermal, and fluid dynamics conundrum. A prime example is the 197 MHz radio frequency dipole (RFD) crabbing cavity proposed for the Electron Ion Collider (EIC) project, exemplifying such complex structures. Our groundbreaking work integrates the localized oxide thickness variation, considering its impact on current distribution and Joule heating, within the framework of multi-physics modeling using the COMSOL® simulation suite. This approach was applied to a comprehensive model of the RFD cavity, allowing us to investigate optimal external cooling water flow conditions necessary for achieving desirable outcomes. In conclusion, this illustrates the increasing utility of such multi-physics codes to greatly aid in designing solutions to challenging processing requirements for increasingly complex accelerator cavities.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Functional wettability in carbonate reservoirs

Oil adsorbs to carbonate reservoirs indirectly through a relatively thick separating water layer, and directly to the surface through a relatively thin intervening water layer. Whereas directly sorbed oil desorbs slowly and incompletely in response to changes in reservoir conditions, indirectly sorbed oil can be rapidly desorbed by changing the chemistry of the separating water layer. The additional recovery might be as much as 30% original oil in place (OOIP) above the ~30% OOIP recovered from carbonates through reservoir depressurization (primary production) and viscous displacement (waterflooding). Electrostatic adhesive forces are the dominant control over carbonate reservoir wettability. A surface complexation model that quantifies electrostatic adhesion accurately predicts oil recovery trends for carbonates. Furthermore, the approach should therefore be useful for estimating initial wettability and designing fluids that improve oil recovery.

02 PETROLEUM↗

A New 1D Model for Thermal Mixing and Stratification in Advanced Reactor Transients

Thermal mixing and stratification in large pools and enclosures play a critical role in the safety and performance of pool-type nuclear reactors, particularly during transient scenarios involving significant temperature differences between incoming and bulk coolant. Accurate modeling of these phenomena is essential for predicting system behavior and supporting passive safety features such as natural circulation. Here, this paper presents a new 1D model for thermal mixing and stratification, developed and implemented in the SAM code. The model represents a large pool as 1D coolant jet channels and zero-dimensional bulk pool volumes, enabling the simulation of a wide range of flow configurations, including hot and cold jet interactions, stratified layers, and the influence of complex geometries such as ceilings, free surfaces, and internal obstacles. Heat exchange between jet and pool regions is governed by closure relations calibrated against 3D computational fluid dynamics (CFD) simulations. The model improves upon earlier approaches by incorporating time-dependent jet characteristics and capturing the associated delay effects more accurately. Code-to-code comparisons and validation against experimental data from the Thermal Stratification Test Facility demonstrate the model’s accuracy and flexibility. This work offers two key contributions: (1) an efficient and robust method for simulating thermal mixing and stratification at the system level, eliminating the need for external coupling between system analysis codes and CFD, and (2) a significant enhancement of SAM’s capabilities to analyze thermal stratification phenomena in advanced reactor systems.

SAM↗

HygroThermFEM v1.0

HygroThermFEM is a Finite Element Method-based numerical calculation engine for solving 2-D heat and moisture transfer problems. This numerical engine is used in the THERM software tool, and its primary purpose is for the analysis of building envelopes (e.g., windows, walls, roofs, foundations, etc.). However, the engine can also be used for any heat and moisture transfer problems that require solving fundamental 2-D energy and mass transfer equations. Fluid flow solutions (Navier-Stokes momentum equations) are not included, but the correlations for various convection heat transfer situations are provided, including the translation of complex cavity geometries into those for which correlations are applicable. The calculation engine is written in C++ and includes an API for connecting to third-party tools.

Vidanovic, Dragan [Lawrence Berkeley National Labo↗

A Machine Learning-Genetic Algorithm (ML-GA) Approach for Rapid Optimization Using High-Performance Computing

A Machine Learning-Genetic Algorithm (ML-GA) approach was developed to virtually discover optimum designs using training data generated from multi-dimensional simulations. Machine learning (ML) presents a pathway to transform complex physical processes that occur in a combustion engine into compact informational processes. In the present work, a total of over 2000 sector-mesh computational fluid dynamics (CFD) simulations of a heavy-duty engine were performed. These were run concurrently on a supercomputer to reduce overall turnaround time. The engine being optimized was run on a low-octane (RON70) gasoline fuel under partially premixed compression ignition (PPCI) mode. A total of nine input parameters were varied, and the CFD simulation cases were generated by randomly sampling points from this nine-dimensional input space. These input parameters included fuel injection strategy, injector design, and various in-cylinder flow and thermodynamic conditions at intake valve closure (IVC). The outputs (targets) of interest from these simulations included five metrics related to engine performance and emissions. Over 2000 samples generated from CFD were then used to train an ML model that could predict these five targets based on the nine input features. A robust super learner approach was employed to build the ML model, where results from a collection of different ML algorithms were pooled together. Thereafter, a stochastic global optimization genetic algorithm (GA) was used, with the ML model as the objective function, to optimize the input parameters based on a merit function so as to minimize fuel consumption while satisfying CO and NOx emissions constraints. The optimized configuration from ML-GA was found to be very close to that obtained from a sequentially performed CFD-GA approach, where a CFD simulation served as the objective function. In addition, the overall turnaround time was (at least) 75% lower with the ML-GA approach, as the training data was generated from concurrent CFD simulations and employing the ML model as the objective function significantly accelerated the GA optimization. Finally, this study demonstrates the potential of ML-GA and high-performance computing (HPC) to reduce the number of CFD simulations to be performed for optimization problems without loss in accuracy, thereby providing significant cost savings compared to traditional approaches.

97 MATHEMATICS AND COMPUTING↗

Adaptive computational methods for SSME internal flow analysis

Adaptive finite element methods for the analysis of classes of problems in compressible and incompressible flow of interest in SSME (space shuttle main engine) analysis and design are described. The general objective of the adaptive methods is to improve and to quantify the quality of numerical solutions to the governing partial differential equations of fluid dynamics in two-dimensional cases. There are several different families of adaptive schemes that can be used to improve the quality of solutions in complex flow simulations. Among these are: (1) r-methods (node-redistribution or moving mesh methods) in which a fixed number of nodal points is allowed to migrate to points in the mesh where high error is detected; (2) h-methods, in which the mesh size h is automatically refined to reduce local error; and (3) p-methods, in which the local degree p of the finite element approximation is increased to reduce local error. Two of the three basic techniques have been studied in this project: an r-method for steady Euler equations in two dimensions and a p-method for transient, laminar, viscous incompressible flow. Numerical results are presented. A brief introduction to residual methods of a-posterior error estimation is also given and some pertinent conclusions of the study are listed.

Oden, J. T.↗

Hypersonic flow analysis

While the zonal grid system of Transonic Navier-Stokes (TNS) provides excellent modeling of complex geometries, improved shock capturing, and a higher Mach number range will be required if flows about hypersonic aircraft are to be modeled accurately. A computational fluid dynamics (CFD) code, the Compressible Navier-Stokes (CNS), is under development to combine the required high Mach number capability with the existing TNS geometry capability. One of several candidate flow solvers for inclusion in the CNS is that of F3D. This upwinding flow solver promises improved shock capturing, and more accurate hypersonic solutions overall, compared to the solver currently used in TNS.

Chow, Chuen-Yen↗

Numerical flow field visualization

The application of computer-generated imagery to analyze numerical solutions of fluid flow is presented. High-performance graphics workstations, their current capabilities, and their use in flow field analysis are discussed. Interactive flow field computations about complex three-dimensional bodies applying computer-generated imagery are projected for the future.

Smith, Robert E.↗

Parallel execution of a three-dimensional, chemically reacting, Navier-Stokes code on distributed-memory machines

This paper describes the parallel version of the three-dimensional, chemically reacting, computational fluid dynamics (CFD) code, SPARK. This work was performed on the Intel iPSC/860-based parallel computers. The SPARK code utilizes relatively simple explicit numerical algorithms, but models complex chemical reactions. The code solves the equations over a regular structured mesh so a simple dam decomposition is used to assign work to the individual processors. The explicit nature of the algorithm, combined with the computational intensity of the chemistry calculations, results in a very low communication-to-computation ratio when compared to typical CFD codes. The efficiency of the parallel code is examined and shown to be about 65 percent when the problem size is scaled with the number of processors. Two low-angle wall-jet injection cases are solved to demonstrate the capability of the parallel code for solving large problems efficiently.

Otto, John C.↗

Large-eddy simulation of a boundary layer with concave streamwise curvature

Turbulence modeling continues to be one of the most difficult problems in fluid mechanics. Existing prediction methods are well developed for certain classes of simple equilibrium flows, but are still not entirely satisfactory for a large category of complex non-equilibrium flows found in engineering practice. Direct and large-eddy simulation (LES) approaches have long been believed to have great potential for the accurate prediction of difficult turbulent flows, but the associated computational cost has been prohibitive for practical problems. This remains true for direct simulation but is no longer clear for large-eddy simulation. Advances in computer hardware, numerical methods, and subgrid-scale modeling have made it possible to conduct LES for flows or practical interest at Reynolds numbers in the range of laboratory experiments. The objective of this work is to apply ES and the dynamic subgrid-scale model to the flow of a boundary layer over a concave surface.

Lund, Thomas S.↗

NASA Low-speed Axial Compressor for Fundamental Research

A low-speed multistage axial compressor built by the NASA Lewis Research Center is described. The purpose of this compressor is to increase the understanding of the complex flow phenomena within multistage axial compressors and to obtain detailed data from a multistage compressor environment for use in developing and verifying models for computational fluid dynamic code assessment. The compressor has extensive pressure instrumentation in both stationary and rotating frames of reference, and has provisions for flow visualization and laser velocimetry. The compressor will accommodate rotational speeds to 1050 rpm and is rated at a pressure ratio of 1.042.

Wasserbauer, Charles A.↗

Textbook Multigrid Efficiency for Computational Fluid Dynamics Simulations

Considerable progress over the past thirty years has been made in the development of large-scale computational fluid dynamics (CFD) solvers for the Euler and Navier-Stokes equations. Computations are used routinely to design the cruise shapes of transport aircraft through complex-geometry simulations involving the solution of 25-100 million equations; in this arena the number of wind-tunnel tests for a new design has been substantially reduced. However, simulations of the entire flight envelope of the vehicle, including maximum lift, buffet onset, flutter, and control effectiveness have not been as successful in eliminating the reliance on wind-tunnel testing. These simulations involve unsteady flows with more separation and stronger shock waves than at cruise. The main reasons limiting further inroads of CFD into the design process are: (1) the reliability of turbulence models; and (2) the time and expense of the numerical simulation. Because of the prohibitive resolution requirements of direct simulations at high Reynolds numbers, transition and turbulence modeling is expected to remain an issue for the near term. The focus of this paper addresses the latter problem by attempting to attain optimal efficiencies in solving the governing equations. Typically current CFD codes based on the use of multigrid acceleration techniques and multistage Runge-Kutta time-stepping schemes are able to converge lift and drag values for cruise configurations within approximately 1000 residual evaluations. An optimally convergent method is defined as having textbook multigrid efficiency (TME), meaning the solutions to the governing system of equations are attained in a computational work which is a small (less than 10) multiple of the operation count in the discretized system of equations (residual equations). In this paper, a distributed relaxation approach to achieving TME for Reynolds-averaged Navier-Stokes (RNAS) equations are discussed along with the foundations that form the basis of this approach. Because the governing equations are a set of coupled nonlinear conservation equations with discontinuities (shocks, slip lines, etc.) and singularities (flow- or grid-induced), the difficulties are many. This paper summarizes recent progress towards the attainment of TME in basic CFD simulations.

Brandt, Achi↗

Assessment of Hybrid RANS/LES Turbulence Models for Aeroacoustics Applications

Predicting the noise from aircraft with exposed landing gear remains a challenging problem for the aeroacoustics community. Although computational fluid dynamics (CFD) has shown promise as a technique that could produce high-fidelity flow solutions, generating grids that can resolve the pertinent physics around complex configurations can be very challenging. Structured grids are often impractical for such configurations. Unstructured grids offer a path forward for simulating complex configurations. However, few unstructured grid codes have been thoroughly tested for unsteady flow problems in the manner needed for aeroacoustic prediction. A widely used unstructured grid code, FUN3D, is examined for resolving the near field in unsteady flow problems. Although the ultimate goal is to compute the flow around complex geometries such as the landing gear, simpler problems that include some of the relevant physics, and are easily amenable to the structured grid approaches are used for testing the unstructured grid approach. The test cases chosen for this study correspond to the experimental work on single and tandem cylinders conducted in the Basic Aerodynamic Research Tunnel (BART) and the Quiet Flow Facility (QFF) at NASA Langley Research Center. These configurations offer an excellent opportunity to assess the performance of hybrid RANS/LES turbulence models that transition from RANS in unresolved regions near solid bodies to LES in the outer flow field. Several of these models have been implemented and tested in both structured and unstructured grid codes to evaluate their dependence on the solver and mesh type. Comparison of FUN3D solutions with experimental data and numerical solutions from a structured grid flow solver are found to be encouraging.

Vatsa, Veer N.↗

Key Gaps for Enabling Plant Growth in Future Missions

Growing plants to provide food or psychological benefits to crewmembers is a common vision for the future of human spaceflight, often represented both in media and in serious concept studies. The complexity of controlled environment agriculture and of plant growth in microgravity have and continue to be the subject of dedicated scientific research. However, actually implementing these systems in a way that will be cost effective, efficient, and sustainable for future space missions is a complex, multi-disciplinary problem. Key questions exist in many areas: human research in nutrition and psychology, horticulture, plant physiology and microbiology, multi-phase microgravity fluid physics, hardware design and technology development, and system design, operations and mission planning. The criticality of the research, and the ideal solution, will vary depending on the mission and type of system implementation being considered.

Anderson, Molly S.↗

Exploration Toilet Integration Challenges on the International Space Station

On the International Space Station (ISS) there are currently two toilets. One is located in the Russian segment's Service Module and the other is located in the U.S. segment's Node 3. A new Exploration Toilet will be integrated next to the existing Node 3 Waste and Hygiene Compartment (WHC). The Toilet will be evaluated as a technology demonstration for a minimum of three years. In addition, it will support an increase in ISS crew size due to Commercial Crew flights to ISS. The Toilet is designed to minimize mass and volume for Orion, the first Exploration vehicle. Currently ISS does not have a designated volume for an additional Toilet. Furthermore, operating the Toilet on ISS presents a different set of challenges as it must integrate into existing vehicle systems for urine processing. To integrate the Toilet on ISS, a suite of hardware was developed to provide mechanical, electrical, data, and fluid interfaces. This paper will provide an overview of the Toilet Integration Hardware design as well as the engineering challenges, crew interface provisions and vehicle integration complexities encountered during the concept and design phases.

Integration Hardware↗