The atmosphere of Mars - A derivation of engineering and design parameters.
Atmosphere of Mars studied using three models generated to show high, mean and low density compositions to account for gravitational and magnetic fields
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Atmosphere of Mars studied using three models generated to show high, mean and low density compositions to account for gravitational and magnetic fields
Parameter optimization, and operation of coaxial plasma injector
Optimum values of pitch rate damping, longitudinal control and speed stability for vertical takeoff aircraft /helicopters/ using pilot ratings
The various meteorological parameters that influence millimeter wavelength satellite-to-ground space diversity links are summarized. Space diversity propagation statistics obtained using the 15.3 GHz down-link on ATS-5 are presented. The radiometric temperature as well as attenuation of the satellite signal was recorded for correlation purposes. Both statistics of individual storm events and cumulative statistics have been analyzed yielding single site and joint fade distributions, correlation between attenuation experienced at the two receiving terminals, and correlation between path radiometric temperatures observed at the two receiving terminals. These data indicate that the use of space diversity is indeed effective in improving the reliability of millimeter wavelength satellite-to-ground communication links.
Shuttle simulation software modules in the environment, crew station, vehicle configuration and vehicle dynamics categories are discussed. For each software module covered, a description of the module functions and operational modes, its interfaces with other modules, its stored data, inputs, performance parameters and critical performance parameters is given. Reference data sources which provide standards of performance are identified for each module. Performance verification methods are also discussed briefly.
Two V/STOL propulsion concepts were evaluated in a common aircraft configuration. One propulsion system consists of cross coupled turboshaft engines driving variable pitch fans. The other system is a gas coupled combination of turbojet gas generators and tip turbine fixed pitch fans. Evaluations were made of endurance at low altitude, low speed loiter with equal takeoff fuel loads. Effects of propulsion system sizing, bypass ratio, and aircraft wing planform parameters were investigated and compared. Shaft driven propulsion systems appear to result in better overall performance, although at higher installed weight, than gas systems.
Two methods of interpreting the misbehavior of reduced order adaptive controllers are discussed. The first method is based on system input-output description and the second is based on state variable description. The implementation of the single input, single output, autoregressive, moving average system is considered.
Recent experiments have shown that low-density gas jets injected into a high-density gas undergo an instability mode leading to highly periodic oscillations in the flow field. The transition from laminar to turbulent flow in these jets is abrupt, without a gradual change in scales. Although this type of instability at high Richardson numbers has been attributed to buoyancy, direct physical evidence was not acquired through experiments. In this study, several experiments were conducted in Earth gravity and microgravity to acquire qualitative data on near field flow structure of helium jets injected into air. Microgravity conditions were simulated in the 2.2-second drop tower at NASA Glenn Research Center. The operating parameters of this study included the tube inside diameter, the jet Reynolds number, and the jet Richardson number. Tubes with inside diameters of 19.05 mm and 31.75 mm were used in the experiments conducted in the drop tower. The jet flow was analyzed using quantitative rainbow schlieren deflectometry, a non-intrusive line of sight measurement technique for the whole field. The flow structure was characterized by distributions of angular deflection and the resulting helium mole fraction obtained from color schlieren images taken at 60 Hz. Three sets of experimental data with respect to three schlieren fields of view were acquired for each tube. Results show that the jet in microgravity was up to 70 percent wider than that in Earth gravity. The global jet flow oscillations observed in Earth gravity were absent in microgravity, providing direct experimental evidence that the flow instability in the low-density jet was buoyancy-induced. This study provides quantitative details of temporal flow evolution as the experiments undergo change in gravity in the drop tower.
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Introduction: An intranasal gel dosage formulation of scopolamine (INSCOP) was developed for the treatment of Space Motion Sickness (SMS), which is commonly experienced by astronauts during space missions. The bioavailability and pharmacokinetics (PK) were evaluated under IND guidelines. Since information is lacking on the effect of gender on the PK of Scopolamine, we examined gender differences in PK parameters of INSCOP at three dose levels of 0.1, 0.2 and 0.4 mg. Methods: Plasma scopolamine concentrations as a function of time data were collected from twelve normal healthy human subjects (6 male/6 female) who participated in a fully randomized double blind crossover study. The PK parameters were derived using WinNonlin. Covariate analysis of PK profiles was performed using NONMEN and statistically compared using a likelihood ratio test on the difference of objective function value (OFV). Statistical significance for covariate analysis was set at P<0.05(ΔOFV=3.84). Results: No significant difference in PK parameters between male and female subjects was observed with 0.1 and 0.2 mg doses. However, CL and Vd were significantly different between male and female subjects at the 0.4 mg dose. Results from population covariate modeling analysis indicate that a onecompartment PK model with first-order elimination rate offers best fit for describing INSCOP concentration-time profiles. The inclusion of sex as a covariate enhanced the model fitting (ΔOFV=-4.1) owing to the genderdependent CL and Vd differences after the 0.4 mg dose. Conclusion: Statistical modeling of scopolamine concentration-time data suggests gender-dependent pharmacokinetics of scopolamine at the high dose level of 0.4 mg. Clearance of the parent compound was significantly faster and the volume of distribution was significantly higher in males than in females, As a result, including gender as a covariate to the pharmacokinetic model of scopolamine offers the best fit for PK modeling of the drug at dose of 0.4 mg or higher.
Dosimetric parameters based on dose-volume histograms (DVH) of contoured structures are routinely used to evaluate dose delivered to target structures and organs at risk. However, the DVH provides no information on the spatial distribution of the dose in situations of repeated fractions with changes in organ shape or size. The aim of this research was to develop methods to more accurately determine geometrically localized, cumulative dose to the bladder wall in intracavitary brachytherapy for cervical cancer. The CT scans and treatment plans of 20 cervical cancer patients were used. Each patient was treated with five high-dose-rate (HDR) brachytherapy fractions of 600cGy prescribed dose. The bladder inner and outer surfaces were delineated using MIM Maestro software (MIM Software Inc.) and were imported into MATLAB (MathWorks) as 3-dimensional point clouds constituting the “bladder wall”. A point-set registration toolbox for MATLAB, Coherent Point Drift (CPD), was used to non-rigidly transform the bladder-wall points from four of the fractions to the coordinate system of the remaining (reference) fraction, which was chosen to be the emptiest bladder for each patient. The doses were accumulated on the reference fraction and new cumulative dosimetric parameters were calculated. The LENT-SOMA toxicity scores of these patients were studied against the cumulative dose parameters. Based on this study, there was no significant correlation between the toxicity scores and the determined cumulative dose parameters.
The feasibility study is performed for the radiative detached divertor (RDD) concept, which characterizes a variety of detached plasmas with impurity amounts providing the highest levels of divertor radiation without X-point MARFE (XPM), based on a set of restrictive criteria for the leading plasma parameters (LPPs) including, e.g., tolerable peak power loads below 1 MW/m2, low separatrix densities, allowable impurity concentrations, and acceptable Z eff values for a DIII-D like tokamak. For this, extensive simulations with the 2-D edge plasma transport code were done scanning the deuterium and impurity inventories practically for all impurity elements from beryllium to neon and the analysis of LPP variations in these scans is presented. It is shown that, for a given D inventory, the total radiation fraction with an increase in the impurity inventory reaches a flat top level, f rad = 0.85 ± 0.01, whereas the higher f rad corresponds to XPM. This critical fraction is the same for all elements and values of the D inventory. Successful RDD solutions with a flat top radiation meeting all ad hoc LPP criteria are found for some elements. Boron and nitrogen are shown to be the most promising elements for seeding, since they are capable of providing alone the successful RDD at the lowest concentrations. Several important effects on impurity radiation are considered including: cross-field impurity transport in regions with strong temperature gradients, multi-species thermal force, charge-exchange of impurity ions with D atoms originating from recombination, impurity entrainment by parallel flows, flows caused by inner/outer divertor asymmetries, and Mach ∼ 1 flows reached inside radiation-ionization fronts. The impurity radiation profiles of various elements are analyzed suggesting three patterns differing in the radiation front position with respect to the D ionization source. The modeled relocation of D from the pedestal into divertor regions; an enhanced pedestal enrichment for impurities with high first ionization potential; and RDD capability of confining inside the divertors the large D inventories as neutral atoms, are considered as effects of increasing impurity inventory. The responses of a flat-top RDD to the input parameters variation are studied. For example, dependencies of LPPs on the input power increase, which express the sharp and even bifurcation transitions between two distinct branches corresponding to the detached and attached divertors, are discussed.
A proposal to study the function of the adrenal gland in the rat during stress is presented. In the proposed project, three different phases of experimentation will be undertaken. The first phase includes establishment of the circadian rhythm of both brain amines and glucocoticoids, under normal conditions and under chronic and acute stressful conditions. The second phase includes the study of the pharmacokinetics of glucocorticoid binding under normal and stress conditions. The third phase includes brain uptake and binding under different experimental conditions. In the outlined experiments brain biogenic amines will be evaluated, adrenal functions will be measured and stress effect on those parameters will be studied. It is hoped that this investigation can explain some of the complex relationships between the brain neurotransmitter and adrenal function.
Thermoluminescence (TL) is a promising technique for rapid screening of the large numbers of Antarctic meteorites, permitting identification of interesting specimens that can then be studied in detail by other, more definite techniques. Specifically, TL permits determination of rough terrestrial age, identification of potential paired groups and location of specimens with unusual pre-fall histories. Meteorites with long terrestrial ages are particularly valuable for studying transport and weathering mechanisms. Pairing studies are possible because TL variations among meteorites are large compared to variations within individual objects, especially for natural TL. Available TL data for several L3 fragments, three of which were paired by other techniques, are presented as an example of the use of TL parameters in pairing studies. Additional TL measurements, specifically a blind test, are recommended to satisfactorily establish the reliability of this pairing property. The TL measurements also identify fragments with unusual pre-fall histories, such an near-Sun orbits.
NASA NEESPI (Northern Eurasia Earth Science Partnership Initiative) data portal is a NASA funded project that focuses on collecting satellite remote sensing data, providing tools, information, and services in support of NEESPI scientific objectives (Leptoukh, et al., 2007). The data can be accessed online through anonymous ftp, through an advanced data searching and ordering system Mirador that uses keywords to find data quickly in a Google-like interface, and through the Goddard Interactive Online Visualization ANd aNalysis Infrastructure (Giovanni). The portal provides preprocessed data from different satellite sensors and numerical models to the same spatial and temporal resolution and the same projection so that the data can be used easily to perform inter-comparison or relationship studies. In addition, it provides parameter and spatially subsetted data for regional studies. Studies of regional carbon, hydrology, aerosols in non-boreal Europe and their interactions with global climate are very challenging research topics. The NASA NEESPI data portal makes many satellite data available for such studies, including information on land cover types, fire, vegetation index, aerosols, land surface temperature, soil moisture, precipitation, snow/ice, and other parameters. This paper will introduce the features and products available in the system, focusing on the online data 1 tool, Giovanni NEESPI. An example that explores different data through Giovanni NEESPI in temperate region of non-boreal Europe will be presented.
The incorporation of lower hybrid (LH) wave spectrum broadening in the poloidal wavenumber (k θ ) space at the last close field surface (LCFS) is reported to lead to better agreement of the modeled LH wave current profile with the experimental results [Baek et al., Nucl. Fusion 61, 106034 (2021)]. To further understand its underlying mechanism and find the possible influence factors, effects of wave scattering caused by drift-wave type density fluctuation on the probability distribution of the LH wave polar refractive index (N θ ) at the LCFS are studied under density parameters in the scrape-off-layer. According to a scattering model [P. T. Bonoli and E. Ott, Phys Fluids 25(2), 359–375 (1982)], scattering probability and scattering angle distribution are two main factors that determine the degree of spectral broadening. Studies presented here show that the total scattering probability increases first and then decreases as the wave propagates toward a smaller normalized radius of poloidal magnetic flux (ρ). The degree of spectral broadening is found to depend on the density and density fluctuation together by changing the intensity and a proportion of the geometrical optics approximation term and the E×B drift term in the scattering model. Additionally, the fluctuation correlation length can significantly modify the probability distribution of N θ at the LCFS, which is found to significantly change the LH wave current profile.
Plasma cathodes are insert free devices that are developed to be employed as electron sources in electric propulsion and ion source applications as practical alternatives to more commonly used hollow cathodes. Inductively coupled plasma cathodes, or Radio Frequency (RF) plasma cathodes, are introduced in recent years. Because of its compact geometry, and simple and efficient plasma generation, RF plasma source is considered to be suitable for plasma cathode applications. In this study, numerous RF plasma cathodes have been designed and manufactured. Experimental measurements have been conducted to study the effects of geometric and operational parameters. Experimental results of this study show that the plasma generation and electron extraction characteristics of the RF plasma cathode device strongly depend on the geometric parameters such as chamber diameter, chamber length, orifice diameter, orifice length, as well as the operational parameters such as RF power and gas mass flow rate.