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At least 1,495 records · Page 83

The Suzaku View of Highly Ionized Outflows in AGN: Statistical Detection and Global Absorber Properties - 1

We present the results of a new spectroscopic study of Fe K-band absorption in active galactic nuclei (AGN). Using data obtained from the Suzaku public archive we have performed a statistically driven blind search for Fe XXV Healpha and/or Fe XXVI Lyalpha absorption lines in a large sample of 51 Type 1.0−1.9 AGN. Through extensive Monte Carlo simulations we find that statistically significant absorption is detected at E greater than or approximately equal to 6.7 keV in 20/51 sources at the P(sub MC) greater than or equal tov 95 per cent level, which corresponds to approximately 40 per cent of the total sample. In all cases, individual absorption lines are detected independently and simultaneously amongst the two (or three) available X-ray imaging spectrometer detectors, which confirms the robustness of the line detections. The most frequently observed outflow phenomenology consists of two discrete absorption troughs corresponding to Fe XXV Healpha and Fe XXVI Lyalpha at a common velocity shift. From xstar fitting the mean column density and ionization parameter for the Fe K absorption components are log (N(sub H) per square centimeter)) is approximately equal to 23 and log (Xi/erg centimeter per second) is approximately equal to 4.5, respectively. Measured outflow velocities span a continuous range from less than1500 kilometers per second up to approximately100 000 kilometers per second, with mean and median values of approximately 0.1 c and approximately 0.056 c, respectively. The results of this work are consistent with those recently obtained using XMM-Newton and independently provides strong evidence for the existence of very highly ionized circumnuclear material in a significant fraction of both radio-quiet and radio-loud AGN in the local universe.

Gofford, Jason↗

Flash Spectroscopy: Emission Lines From the Ionized Circumstellar Material Around 10-Day-Old Type II Supernovae

Supernovae (SNe) embedded in dense circumstellar material (CSM) may show prominent emission lines in their early-time spectra (< or =10 days after the explosion), owing to recombination of the CSM ionized by the shock-breakout flash. From such spectra ("flash spectroscopy"), we can measure various physical properties of the CSM, as well as the mass-loss rate of the progenitor during the year prior to its explosion. Searching through the Palomar Transient Factory (PTF and iPTF) SN spectroscopy databases from 2009 through 2014, we found 12 SNe II showing flash-ionized (FI) signatures in their first spectra. All are younger than 10 days. These events constitute 14% of all 84 SNe in our sample having a spectrum within 10 days from explosion, and 18% of SNe II observed at ages <5 days, thereby setting lower limits on the fraction of FI events. We classified as "blue/featureless" (BF) those events having a first spectrum that is similar to that of a blackbody, without any emission or absorption signatures. It is possible that some BF events had FI signatures at an earlier phase than observed, or that they lack dense CSM around the progenitor. Within 2 days after explosion, 8 out of 11 SNe in our sample are either BF events or show FI signatures. Interestingly, we found that 19 out of 21 SNe brighter than an absolute magnitude M(sub R) = −18.2 belong to the FI or BF groups, and that all FI events peaked above M(sub R) = −17.6 mag, significantly brighter than average SNe II.

supernovae: general↗

Gemini Near Infrared Field Spectrograph Observations of the Seyfert 2 Galaxy MRK 573: In Situ Acceleration of Ionized and Molecular Gas Off Fueling Flows

We present near-infrared and optical emission-line and stellar kinematics of the Seyfert 2 galaxy Mrk 573 using the Near-Infrared Field Spectrograph (NIFS) at Gemini North and Dual Imaging Spectrograph at Apache Point Observatory, respectively. By obtaining full kinematic maps of the infrared ionized and molecular gas and stellar kinematics in approximately 700 x 2100 pc(exp 2) circumnuclear region of Mrk 573, we find that kinematics within the Narrow-Line Region are largely due to a combination of both rotation and in situ acceleration of material originating in the host disk. Combining these observations with large-scale, optical long-slit spectroscopy that traces ionized gas emission out to several kpcs, we find that rotation kinematics dominate the majority of the gas. We find that outflowing gas extends to distances less than 1 kpc, suggesting that outflows in Seyfert galaxies may not be powerful enough to evacuate their entire bulges.

galaxies: active – galaxies: individual (Mrk 573↗

Effect of Additives: Gamma-Ray Sensors Based on Ionizing Organic Nanocomposites

We have developed ionizing organic-based composites which have demonstrated great promise for radiation sensing. Nickel oxide has been proven as an active material for detecting high energy radiation. The oxidation state of unusual oxides such as nickel oxide in nanocomposites of ionizing organics changes much faster than thin film or bulk, and hence increases the sensitivity for radiation sensing. The resistivity of the oxide composite increases following sequential irradiation processes because of the decrease in holes' concentration. In this paper, we will present the effect of additional oxidizing agent on the morphology, processing and sensing of gamma-rays by oxides - urea based nanocomposites. It was observed that addition of MnO2 decreases the sensitivity. However, it recovers to original properties after irradiation much faster than undoped composites.

Vishall Dayal↗

Predicting Cancer Risk from Ionizing Radiation

The ability to predict cancer risk associated with exposure to low doses of high-LET ionizing radiation (IR) remains a challenge. Epidemiological methods lack the sensitivity and power to provide detailed risk estimates for cancer and ignore individual variance in IR sensitivity. We have hypothesized that DNA repair capacity can be used as a marker to evaluate and differentiate individual radiation sensitivity. More specifically, this work is based on the concept that the combined time-dose dependence of radiation-induced foci (RIF) of p53-binding protein 1 (53BP1) following low-LET exposure contains sufficient information to infer sensitivity to any other LET. Our hypothesis was tested in 15 different mouse strains as well as in primary human immune cells. We first approached individual ionizing radiation sensitivity in a mouse model by culturing primary skin fibroblasts extracted from 76 mice of 15 different genetic backgrounds and exposing them to HZE particles and X-rays. This work is one of the most extensive studies on the kinetics and possible genetic underpinnings of radiation-induced DNA damage and repair. Our results is in agreement with a DNA repair model we previously postulated, where nearby DNA double strand breaks (DSB) in the nucleus are brought together for more efficient repair, leading to RIF clustering. Such mechanism was evidenced by a specific dose and LET dependence of RIF numbers. Briefly, RIF quantification after low-LET X-ray exposure showed an asymptotic saturation for doses between 1 Gy and 4 Gy 4 hours post-irradiation across all 15 strains. The clustering of DSB across all strains also led to more RIF/Gy for lower LET (X-ray and 350 MeV/n Ar) than for higher LET (600 MeV/n Fe) 4 hours post-exposure. Considering the fact that the number of DSB/Gy should be independent of LET, our data suggest there are more DSB in individual RIF as the LET increases. RIF numbers for 24 and 48 hours post-exposure led to the inverse trend, with more remaining RIF/Gy for higher LET (by 600 MeV/n Fe). This result suggests cells have more difficulty resolving RIF from higher LET as they the number DSB/RIF increases. Note that for most conditions, the variance of RIF/Gy was small within individual animals of the same strain and large between strains, suggesting a strong genetics component. Furthermore, we present our preliminary data from an ongoing study on human genetic associations with IR sensitivity. To address the human variability in responses to HZE particle irradiation in a maximally comprehensive manner, we are in the process of collecting and isolating primary blood mononuclear cells from 768 healthy subjects of European descent, 18-75 years of age, 50/50 male/female distribution. We have analyzed 53BP1+ RIF formation as well as oxidative stress and cell death in primary cells from 192 subjects in response to the same HZE particles as used in mice: 600 MeV/n Fe, 350 MeV/n Ar and 350 MeV/n Si, 1.1 and 3 particles/100m2, 4 and 24 hours after irradiation. We will next complete the quantification of HZE particle-induced DNA and cellular damage in the remaining subjects and compare it to their responses to low-LET irradiation. Finally, we will perform GWAS analysis to identify human genomic associations with IR sensitivity and potential targets for biomarker development.

High-LET radiation↗

Dried Plum Diet Prevents Bone Loss Caused by Ionizating Radiation: Reduces Pro-Resorption Cytokine Expression, and Protects Marrow-Derived Osteoprogenitors

Future long duration missions outside the protection of the Earth's magnetosphere, or unshielded exposures to solar particle events, achieves total doses capable of causing cancellous bone loss. Cancellous bone loss caused by ionizing radiation occurs quite rapidly in rodents: Initially, radiation increases the number and activity of bone-resorbing osteoclasts, followed by decrease in bone forming osteoblast cells. Here we report that Dried Plum (DP) diet completely prevented cancellous bone loss caused by ionizing radiation (Figure 1). DP attenuated marrow expression of genes related to bone resorption (Figure 2), and protected the bone marrow-derived pre-osteoblasts ex vivo from total body irradiation (Figure 3). DP is known to inhibit resorption in models of aging and ovariectomy-induced osteopenia; this is the first report that dietary DP is radioprotective.

Radioprotective↗

NASA GeneLab Space Omics Database: Expanding from Space to Ionizing Radiation Data on the Ground

NASA GeneLab is an open-access repository for omics datasets generated by biological experiments conducted in space or ground experiments relevant to spaceflight (e.g. simulated cosmic radiation, simulated microgravity, bed rest studies). The GeneLab Data Systems (GLDS) version 4.0 will be available on October 1st 2019, and will provide a state-of-the-art bioinformatics platform for the space biology and radiation communities to upload their data into an omics data commons, to process their data with vetted standard workflows and to compare with existing analyses. Started in 2015 as a repository designed to archive omics data from space experiments, GeneLab has expanded its scope to all ionizing radiation omics experiments conducted on the ground and has put considerable effort in providing carefully characterized radiation metadata on all datasets. GeneLab is also providing processed data derived from the raw data covering a large spectrum of omics (genome, epigenome, transcriptome, epitranscriptome, proteome, metabolome) to help users explore important questions: 1) Which genes or proteins are expressed differently in space for various living organisms? 2) What specific DNA mutations or epigenetic changes happen in space or after exposure to ionizing radiation? and 3) How does genetics affect these responses? Processed data available on GeneLab are derived by standard data analysis workflows vetted by hundreds of scientists who volunteered to join one of the four GeneLab Analysis Working Groups (Animal AWG, Plant AWG, Microbe AWG, Multi-Omics AWG). In this presentation, we will discuss how to bridge the gap between irradiation studies performed on earth and biological experiments conducted in space since the early 1990's. We will discuss how radiation dosimetry was estimated for datasets derived from samples collected during the Space Shuttle era on the International Space Station and on other orbiting platforms. Finally, we will address future strategies regarding dose monitoring in future missions into space, inter-agency efforts to unify data under one umbrella, and knowledge dissemination across the radiation research community and the space biology community.

open-science↗

Rest-Frame UV and Optical Emission Line Diagnostics of Ionized Gas Properties: a Test Case in a Star-Forming Knot of a Lensed Galaxy at Z ∼ 1.7

We examine the diagnostic power of rest-frame ultraviolet (UV) nebular emission lines, and compare them to more commonly used rest-frame optical emission lines, using the test case of a single star-forming knot of the bright lensed galaxy RCSGA 032727–132609 at redshift z ∼ 1.7. This galaxy has complete coverage of all the major rest-frame UV and optical emission lines from Magellan/MagE and Keck/NIRSPEC. Using the full suite of diagnostic lines, we infer the physical properties: nebular electron temperature (T(sub e)), electron density (n(sub e)), oxygen abundance (log (O/H), ionization parameter [log (q), and interstellar medium (ISM) pressure (log (P/k)]. We examine the effectiveness of the different UV, optical, and joint UV–optical spectra in constraining the physical conditions. Using UV lines alone we can reliably estimate log (q), but the same is difficult for log (O/H). UV lines yield a higher (∼1.5 dex) log (P/k) than the optical lines, as the former probes a further inner nebular region than the latter. For this comparison, we extend the existing Bayesian inference code IZI, adding to it the capability to infer ISM pressure simultaneously with metallicity and ionization parameter. This work anticipates future rest-frame UV spectral data sets from the James Webb Space Telescope (JWST) at high redshift and from the Extremely Large Telescope (ELT) at moderate redshift.

Acharyya, Ayan↗

Neurovascular Outcomes of Ionizing Radiation in Human Blood-Brain Barrier Models

One of the main health risks in human deep space exploration is central nervous system (CNS) damage by ionizing radiation due to exposure to galactic cosmic rays (GCRs). In animal models, irradiation with simulated GCRs or their components has been shown to cause neurodegeneration and neuroinflammation associated with cognitive and behavioral dysfunction. The extent of CNS damage is partially mediated by the blood-brain barrier (BBB), which regulates the interaction between CNS and systemic responses to stressors in the rest of the body. The main cellular regulators of BBB permeability are astrocytes, which also modulate neuronal death, neuroinflammation and oxidative stress. However, studies on BBB and astrocyte functions in regulating CNS responses to ionizing radiation have been limited, especially in human tissue/organ analogs. Therefore, we developed a high throughput 3D human neurovascular system model, based on commercially available Mimetas OrganoPlates seeded by primary human cells, to investigate the neurovascular responses to simulated deep space radiation. Using this system, we have demonstrated that 600MeV/n 56Fe irradiation leads to cellular damage and increased blood-brain barrier permeability via dysfunction of brain cells called astrocytes, which appear to be the weakest link and therefore a highly suitable countermeasure target to reduce the impact of space radiation on the blood-brain barrier. We anticipate that our results form merely the first step in ongoing development of organ models, including their adaptation for personalized risk assessment, high throughput approaches to countermeasure screening and validation, and eventual payload adaptation.

organ-on-a-chip↗

Discovery of a Fast Iron Low-ionization Outflow in the Early Evolution of the Nearby Tidal Disruption Event AT 2019qiz

We report the results of ultraviolet (UV) and optical photometric and spectroscopic analysis of the tidal disruption event (TDE) AT 2019qiz. Our follow-up observations started <10 days after the source began to brighten in the optical and lasted for a period of six months. Our late-time host-dominated spectrum indicates that the host galaxy likely harbors a weak active galactic nucleus. The initial Hubble Space Telescope (HST) spectrum of AT 2019qiz exhibits an iron and low-ionization broad absorption line (FeLoBAL) system that is seen for the first time in a TDE. This spectrum also bears a striking resemblance to that of Gaia16apd, a superluminous supernova. Our observations provide insights into the outflow properties in TDEs and show evidence for a connection between TDEs and engine-powered supernovae at early phases, as originally suggested by Metzger & Stone (2016). In a time frame of 50 days, the UV spectra of AT 2019qiz started to resemble those of previous TDEs with only high-ionization BALs. The change in UV spectral signatures is accompanied by a decrease in the outflow velocity, which began at 15,000 km/s and decelerated to ~ 10,000 km/s. A similar evolution in the Ha emission-line width further supports the speculation that the broad Balmer emission lines are formed in TDE outflows. In addition, we detect narrow absorption features on top of the FeLoBAL signatures in the early HST UV spectrum of AT 2019qiz. The measured H I column density corresponds to a Lyman-limit system, whereas the metal absorption lines (such as N V, C IV, Fe II, and Mg II) are likely probing the circumnuclear gas and interstellar medium in the host galaxy.

Tiara Hung↗

Elevated Hot Gas and High-mass X-Ray Binary Emission in Low-metallicity Galaxies: Implications for Nebular Ionization and Intergalactic Medium Heating in the Early Universe

High-energy emission associated with star formation has been proposed as a significant source of interstellar medium (ISM) ionization in low-metallicity starbursts and an important contributor to the heating of the intergalactic medium (IGM) in the high-redshift (z ≳ 8) universe. Using Chandra observations of a sample of 30 galaxies at D ≈ 200–450 Mpc that have high specific star formation rates of 3–9 Gyr^(−1) and metallicities near Z ≈ 0.3Z_⊙, we provide new measurements of the average 0.5–8 keV spectral shape and normalization per unit star formation rate (SFR). We model the sample-combined X-ray spectrum as a combination of hot gas and high-mass X-ray binary (HMXB) populations and constrain their relative contributions. We derive scaling relations of log L^(HMXB)_(0.5-8keV) / SFR = 40.19 ± 0.06 and log L^(gas)_(0.5-2keV) / SFR = 39.58 ^(+0.17)_(-0.28), significantly elevated compared to local relations. The HMXB scaling is also somewhat higher than L^(HMXB)_(0.5-8keV) -SFR-Z relations presented in the literature, potentially due to our galaxies having relatively low HMXB obscuration and young and X-ray luminous stellar populations. The elevation of the hot gas scaling relation is at the level expected for diminished attenuation due to a reduction of metals; however, we cannot conclude that an L^(gas)_(0.5-2keV) -SFR-Z relation is driven solely by changes in ISM metal content. Finally, we present SFR-scaled spectral models (both emergent and intrinsic) that span the X-ray-to-IR band, providing new benchmarks for studies of the impact of ISM ionization and IGM heating in the early universe.

high-mass x-ray binary stars↗

NAIRAS Model Updates and Improvements to the Prediction of the Ionizing Radiation Environment from the Earth's Surface to Geospace

- NAIRAS Model Description - Nowcast of Aerospace Ionizing RAdiation System (NAIRAS) Model - Running in real-time on LaRC computer cluster since 2011, results hosted on Space Environment Technologies server/website - Running in real-time at CCMC since 2020 - Key Model Features - Global ionizing radiation environment model - Physics-based HZETRN (High Charge (Z) and Energy TRaNsport) code - Real-time inclusion of solar energetic particle (SEP) radiation - Real-time solar-magnetospheric effects on radiation (cutoff model by Kress et al. [2004, 2010]) - New/Current Model Development - Improved SEP dose nowcast and forecast - Extend to low-Earth orbit (LEO) environment - Single-Event Effects (SEE) radiation risk assessment quantities - Run-on-Request (RoR) @ CCMC

Christopher J. Mertens↗

NAIRAS Ionizing Radiation Model: Extension from Atmosphere to Space

The Nowcast of Aerospace Ionizing RAdiation System (NAIRAS) model is a real-time, global, physics-based model originally developed to predict exposure from cosmic radiation to air travelers from both galactic and solar sources. A prototype operational NAIRAS model has provided tabular and graphical data products via its public web site for about ten years. A new version of the NAIRAS model has been developed that incorporates an extension of the model domain from the atmospheric ionizing radiation environment to the space radiation environment, with the addition of the trapped inner belt proton source and altitude-dependent and rigidity-dependent geomagnetic shielding of the galactic cosmic rays (GCR) and solar energetic particle (SEP) protons. New output products of differential and integral particle flux have been developed for the characterization of single-event effects (SEE), expanding the application of NAIRAS from human radiation exposure assessment to allowing end-users to quantify radiation environment risks to aviation and spacecraft microelectronic systems. The NAIRAS model has transitioned to prototype operations at the Community Coordinated Modeling Center (CCMC) where the model now operates in two modes: (1) real-time global predictions of the atmospheric radiation environment and (2) a run-on-request (RoR) service allowing the user to select a specific time period for the global dosimetric calculations, or to upload an aircraft, balloon, or spaceflight trajectory file to provide predictions of the dosimetric and particle flux quantities along the flight path. The new features of NAIRAS version 3.0 are described in this paper and example results of the new output products for low-Earth orbit (LEO), medium-Earth orbit (MEO), and free-space radiation environments are presented

Christopher J. Mertens↗

Comparison of the Nowcast of Aerospace Ionizing Radiation System (NAIRAS) With ISS Measurements

The Nowcast of Aerospace Ionizing Radiation System (NAIRAS) is a sophisticated physics-based model that has been providing real-time global predictions of cosmic radiation exposure, pertinent to both galactic and solar sources, to air travelers for a decade. The utility of NAIRAS, however, extends beyond the atmospheric ionizing radiation environment. The recently developed NAIRAS 3.0 version demonstrates an expansion of its domain to the space radiation environment. This extension incorporates an additional trapped inner belt proton source, coupled with altitude-dependent and rigidity-dependent geomagnetic shielding for galactic cosmic rays (GCR) and solar energetic particle (SEP) protons. The latest version of NAIRAS operates in two modes: real-time global predictions of the atmospheric radiation environment and a user-specified run-on-request service for global dosimetric calculations or predictions of dosimetric and particle flux quantities along user-uploaded flight path. It is available to the public at the Community Coordinated Modeling Center (CCMC). In this work, we present the validation exercises that have been conducted using the Automated Radiation Measurements for Aerospace Safety (ARMAS) onboard the International Space Station (ISS), thereby establishing NAIRAS's efficacy in predicting space radiation exposure. As such, NAIRAS 3.0 holds significant potential for human safety and technological advancement in aerospace travel and exploration.

Daniel Phoenix↗

The Effect of a SEP Event on Astronauts Doing a Spacewalk As Computed By the Nowcast of Aerospace Ionizing Radiation System (NAIRAS)

The Nowcast of Aerospace Ionizing Radiation System (NAIRAS) is a sophisticated physics-based model that has been providing real-time global predictions of cosmic radiation exposure, pertinent to both galactic and solar sources, to air travelers for a decade. The utility of NAIRAS, however, extends beyond the atmospheric ionizing radiation environment. The recently developed NAIRAS 3.0 version demonstrates an expansion of its domain to the space radiation environment. This extension incorporates an additional trapped inner belt proton source, coupled with altitude-dependent and rigidity-dependent geomagnetic shielding for galactic cosmic rays (GCR) and solar energetic particle (SEP) protons. The latest version of NAIRAS operates in two modes: real-time global predictions of the atmospheric radiation environment and a user-specified run-on-request service for global dosimetric calculations or predictions of dosimetric and particle flux quantities along user-uploaded flight path. It is available to the public at the Community Coordinated Modeling Center (CCMC). In this work, we present the computations of the dose in the ISS vicinity during the SEP event of August 8, 2023; which happened a day before a scheduled spacewalk. We demonstrate that astronauts would not have suffered a dose equivalent in excess of 1 mSv if the event happened a day later. As such, NAIRAS 3.0 holds significant potential for human safety and technological advancement in aerospace travel and exploration.

Guillaume Gronoff↗

Phase space density as a measure of cooling performance for the international muon ionization cooling experiment

The International Muon Ionization Cooling Experiment (MICE) is an experiment to demonstrate ionization cooling of a muon beam in a beamline that shares characteristics with one that might be used for a muon collider or neutrino factory. I describe a way to quantify cooling performance by examining the phase space density of muons, and determining how much that density increases. This contrasts with the more common methods that rely on the covariance matrix and compute emittances from that. I discuss why a direct measure of phase space density might be preferable to a covariance matrix method. I apply this technique to an early proposal for the MICE final step beamline. I discuss how matching impacts the measured performance.

43 PARTICLE ACCELERATORS↗

NMR Metabolomics in Ionizing Radiation

Ionizing radiation is an invisible threat that cannot be seen, touched or smelled and exist either as particles or waves. Particle radiation can take the form of alpha, beta or neutrons, as well as high energy space particle radiation such as high energy iron, carbon and proton radiation, etc. (1) Non-particle radiation includes gamma- and x-rays. Publically, there is a growing concern about the adverse health effects due to ionizing radiation mainly because of the following facts. (a) The X-ray diagnostic images are taken routinely on patients. Even though the overall dosage from a single X-ray image such as a chest X-ray scan or a CT scan, also called X-ray computed tomography (X-ray CT), is low, repeated usage can cause serious health consequences, in particular with the possibility of developing cancer (2, 3). (b) Human space exploration has gone beyond moon and is planning to send human to the orbit of Mars by the mid-2030s. And a landing on Mars will follow.

Environmental Molecular Sciences Laboratory↗

Method for detecting and distinguishing between specific types of environmental radiation using a high pressure ionization chamber with pulse-mode readout

An environmental radiation detector for detecting and distinguishing between all types of environmental radiation, including photons, charged particles, and neutrons. A large volume high pressure ionization chamber (HPIC) includes BF.sub.3 gas at a specific concentration to render the radiation detector sensitive to the reactions of neutron capture in Boron-10 isotope. A pulse-mode readout is connected to the ionization chamber capable of measuring both the height and the width of the pulse. The heavy charged products of the neutron capture reaction deposit significant characteristic energy of the reaction in the immediate vicinity of the reaction in the gas, producing a signal with a pulse height proportional to the reaction energy, and a narrow pulse width corresponding to the essentially pointlike energy deposition in the gas. Readout of the pulse height and the pulse width parameters of the signals enables distinguishing between the different types of environmental radiation, such as gamma (x-rays), cosmic muons, and neutrons.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗