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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 1,495 records · Page 83
All sourcesNASA NTRSDOE OSTI
DOE OSTI2010

Ion Bombardment of Microprotrusions in High Gradient Accelerating Structures

This paper starts from a brief overview of theoretical studies of high-gradient accelerating structures at the University of Maryland. The rest of the paper is devoted to the analysis of ion bombardment of small protrusions in such structures. First, this problem is studied analytically. Then, some results of particle-in-cell simulations performed with the use of code WARP are presented and discussed.

43 PARTICLE ACCELERATORS↗
NASA NTRSDate not supplied

Gateway Integrated ECLSS Model Analysis of Intermodule Ventilation Failures

The Gateway Integrated ECLSS Model (GIEM) is a set of two independent models, made in Aspen Custom Modeler (ACM) and Thermal Desktop (TD), of the Gateway stack and each modules' associated environment control and life support system (ECLSS). The GIEM utilizes the 41-Node Metabolic Man (METMAN) to simulate crew inside the Gateway consuming O2 and producing CO2, H2O, and heat for the ECLSS to remove. The modules and visiting vehicles all have different levels of ECLSS capabilities and may rely on other modules and Intermodular Ventilation (IMV), which is used to exchange gas between the modules, to ensure the entire Gateway environment is controlled. If IMV were to fail or be turned off, some vehicles may have limited access to necessary ECLSS functions. This analysis focuses on evaluating O2, CO2, and H2O levels when crew are in vehicles without their own life support and IMV has failed to evaluate how long before the atmosphere is unsafe for the crew. This analysis uses the integrated nature of the GIEM to look at time to effect for O2 depletion and CO2 and H2O buildup when crew are working in vehicles that have been cut off from the ECLSS-active portion of the stack. This information is used to inform for how long crew can safely continue working in the ECLSS-inactive vehicles before experiencing a requirement violation or physical limitation and can be referenced when developing maintenance and emergency response concept of operations (ConOps).

Lawrence Barrett↗
DOE OSTI2022

Accelerating cosmological inference with Gaussian processes and neural networks – an application to LSST Y1 weak lensing and galaxy clustering

ABSTRACT Studying the impact of systematic effects, optimizing survey strategies, assessing tensions between different probes and exploring synergies of different data sets require a large number of simulated likelihood analyses, each of which cost thousands of CPU hours. In this paper, we present a method to accelerate cosmological inference using emulators based on Gaussian process regression and neural networks. We iteratively acquire training samples in regions of high posterior probability which enables accurate emulation of data vectors even in high dimensional parameter spaces. We showcase the performance of our emulator with a simulated 3×2 point analysis of LSST-Y1 with realistic theoretical and systematics modelling. We show that our emulator leads to high-fidelity posterior contours, with an order of magnitude speed-up. Most importantly, the trained emulator can be re-used for extremely fast impact and optimization studies. We demonstrate this feature by studying baryonic physics effects in LSST-Y1 3×2 point analyses where each one of our MCMC runs takes approximately 5 min. This technique enables future cosmological analyses to map out the science return as a function of analysis choices and survey strategy.

Astronomy & Astrophysics↗
DOE OSTI2011

Exact solutions of fractional Schroedinger-like equation with a nonlocal term

We study the time-space fractional Schroedinger equation with a nonlocal potential. By the method of Fourier transform and Laplace transform, the Green function, and hence the wave function, is expressed in terms of H-functions. Graphical analysis demonstrates that the influence of both the space-fractal parameter {alpha} and the nonlocal parameter {nu} on the fractional quantum system is strong. Indeed, the nonlocal potential may act similar to a fractional spatial derivative as well as fractional time derivative.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2016

Comparative genomics and evolution of transcriptional regulons in Proteobacteria

Comparative genomics approaches are broadly used for analysis of transcriptional regulation in bacterial genomes. In this work, we identified binding sites and reconstructed regulons for 33 orthologous groups of transcription factors (TFs) in 196 reference genomes from 21 taxonomic groups of Proteobacteria. Overall, we predict over 10 600 TF binding sites and identified more than 15 600 target genes for 1896 TFs constituting the studied orthologous groups of regulators. These include a set of orthologues for 21 metabolism-associated TFs from Esc herichia coli and/or Shewanella that are conserved in five or more taxonomic groups and several additional TFs that represent non-orthologous substitutions of the metabolic regulators in some lineages of Proteobacteria. By comparing gene contents of the reconstructed regulons, we identified the core, taxonomy-specific and genome-specific TF regulon members and classified them by their metabolic functions. Detailed analysis of ArgR, TyrR, TrpR, HutC, HypR and other amino-acid-specific regulons demonstrated remarkable differences in regulatory strategies used by various lineages of Proteobacteria. The obtained genomic collection of in silico reconstructed TF regulons contains a large number of new regulatory interactions that await future experimental validation. The collection provides a framework for future evolutionary studies of transcriptional regulatory networks in Bacteria. It can be also used for functional annotation of putative metabolic transporters and enzymes that are abundant in the reconstructed regulons.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2013

Wet chemical synthesis and characterization of AgGaSe{sub 2} nanoparticles

AgGaSe{sub 2} compound semiconductor nanoparticles were synthesized by wet chemical method using mercaptoacetic acid as a capping agent at room temperature. The synthesized powders belong to chalcopyrite structure confirmed by powder XRD. The surface morphology and crystalline size were observed by high resolution scanning electron microscope (HR-SEM). The stoichiometric composition of AgGaSe{sub 2} nanoparticles was confirmed by Energy dispersive X-ray (EDX) analysis. Different functional group vibrations of mercaptoacetic acid capped nanoparticles were studied using FT-IR spectrum. The absorbance and optical bandgap of the nanoparticles were determined using diffuse reflectance spectroscopy (DRS).

36 MATERIALS SCIENCE↗
DOE OSTI2012

Electric dipole polarizability and the neutral skin

The recent high-resolution measurement of the electric dipole (E1) polarizability {alpha}{sub D} in {sup 208}Pb [A. Tamii et al. Phys. Rev. Lett. 107 062502 (2011)] provides a unique constraint on the neutron-skin thickness of this nucleus. The neutron-skin thickness r{sub skin} of {sup 208}Pb is a quantity of critical importance for our understanding of a variety of nuclear and astrophysical phenomena. To assess the model dependence of the correlation between {alpha}{sub D} and r{sub skin}, we carry out systematic calculations for {sup 208}Pb, {sup 132}Sn, and {sup 48}Ca based on the nuclear density functional theory using both nonrelativistic and relativistic energy density functionals. Our analysis indicates that whereas individual models exhibit a linear dependence between {alpha}{sub D} and r{sub skin}, this correlation is not universal when one combines predictions from a host of different models. By averaging over these model predictions, we provide estimates with associated systematic errors for r{sub skin} and {alpha}{sub D} for the nuclei under consideration. We conclude that precise measurements of r{sub skin} in both {sup 48}Ca and {sup 208}Pb - combined with the recent measurement of {alpha}{sub D} - should significantly constrain the isovector sector of the nuclear energy density functional.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗
DOE OSTI2015

Coherent states for nonlinear harmonic oscillator and some of its properties

A one-dimensional nonlinear harmonic oscillator is studied in the context of generalized coherent states. We develop a perturbative framework to compute the eigenvalues and eigenstates for the quantum nonlinear oscillator and construct the generalized coherent states based on Gazeau-Klauder formalism. We analyze their statistical properties by means of Mandel parameter and second order correlation function. Our analysis reveals that the constructed coherent states exhibit super-Poissonian statistics. Moreover, it is shown that the coherent states mimic the phenomena of quantum revivals and fractional revivals during their time evolution. The validity of our results has been discussed in terms of various parametric bounds imposed by our computational scheme.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2024

Structure and phase transitions in niobium and tantalum derived nanoscale transition metal perovskites, Ba(Ti,MV)O3, M=Nb,Ta

The prospect of creating ferroelectric or high permittivity nanomaterials provides motivation for investigating complex transition metal oxides of the form Ba(Ti, MV)O3, where M = Nb or Ta. Solid state processing typically produces mixtures of crystalline phases, rarely beyond minimally doped Nb/Ta. Using a modified sol-gel method, we prepared single phase nanocrystals of Ba(Ti, M)O3. Compositional and elemental analysis puts the empirical formulas close to BaTi0.5Nb0.5O3−δ and BaTi0.5Ta0.5O3−δ. For both materials, a reversible temperature dependent phase transition (non-centrosymmetric to symmetric) is observed in the Raman spectrum in the region 533–583 K (260–310 °C); for Ba(Ti, Nb)O3, the onset is at 543 K (270 °C); and for Ba(Ti, Ta)O3, the onset is at 533 K (260 °C), which are comparable with 390–393 K (117–120 °C) for bulk BaTiO3. The crystal structure was resolved by examination of the powder x-ray diffraction and atomic pair distribution function (PDF) analysis of synchrotron total scattering data. It was postulated whether the structure adopted at the nanoscale was single or double perovskite. Double perovskites (A2B′B″O6) are characterized by the type and extent of cation ordering, which gives rise to higher symmetry crystal structures. PDF analysis was used to examine all likely candidate structures and to look for evidence of higher symmetry. The feasible phase space that evolves includes the ordered double perovskite structure Ba2(Ti, MV)O6 (M = Nb, Ta) Fm-3m, a disordered cubic structure, as a suitable high temperature analog, Ba(Ti, MV)O3Pm-3m, and an orthorhombic Ba(Ti, MV)O3Amm2, a room temperature structure that presents an unusually high level of lattice displacement, possibly due to octahedral tilting, and indication of a highly polarized crystal.

Chemistry↗
DOE OSTI2016

Reflection imaging of the Moon's interior using deep-moonquake seismic interferometry

The internal structure of the Moon has been investigated over many years using a variety of seismic methods, such as travel time analysis, receiver functions, and tomography. Here we propose to apply body-wave seismic interferometry to deep moonquakes in order to retrieve zero-offset reflection responses (and thus images) beneath the Apollo stations on the nearside of the Moon from virtual sources colocated with the stations. This method is called deep-moonquake seismic interferometry (DMSI). Our results show a laterally coherent acoustic boundary around 50 km depth beneath all four Apollo stations. We interpret this boundary as the lunar seismic Moho. This depth agrees with Japan Aerospace Exploration Agency's (JAXA) SELenological and Engineering Explorer (SELENE) result and previous travel time analysis at the Apollo 12/14 sites. The deeper part of the image we obtain from DMSI shows laterally incoherent structures. Finally, such lateral inhomogeneity we interpret as representing a zone characterized by strong scattering and constant apparent seismic velocity at our resolution scale (0.2–2.0 Hz).

58 GEOSCIENCES↗
DOE OSTI2011

Optimization of Micro Metal Injection Molding By Using Grey Relational Grade

Micro metal injection molding ({mu}MIM) which is a variant of MIM process is a promising method towards near net-shape of metallic micro components of complex geometry. In this paper, {mu}MIM is applied to produce 316L stainless steel micro components. Due to highly stringent characteristic of {mu}MIM properties, the study has been emphasized on optimization of process parameter where Taguchi method associated with Grey Relational Analysis (GRA) will be implemented as it represents novel approach towards investigation of multiple performance characteristics. Basic idea of GRA is to find a grey relational grade (GRG) which can be used for the optimization conversion from multi objectives case which are density and strength to a single objective case. After considering the form 'the larger the better', results show that the injection time(D) is the most significant followed by injection pressure(A), holding time(E), mold temperature(C) and injection temperature(B). Analysis of variance (ANOVA) is also employed to strengthen the significant of each parameter involved in this study.

36 MATERIALS SCIENCE↗
DOE OSTI2012

Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: Protein synthesis, cell proliferation, and T-cell activation

Human immunodeficiency virus (HIV-1) depends upon host-encoded proteins to facilitate its replication while at the same time inhibiting critical components of innate and/or intrinsic immune response pathways. To characterize the host cell response on protein levels in CD4+ lymphoblastoid SUP-T1 cells after infection with HIV-1 strain LAI, we used mass spectrometry (MS)-based global quantitation with iTRAQ (isobaric tag for relative and absolute quantification). We found 266, 60 and 22 proteins differentially expressed (DE) (P-value{<=}0.05) at 4, 8, and 20 hours post-infection (hpi), respectively, compared to time-matched mock-infected samples. The majority of changes in protein abundance occurred at an early stage of infection well before the de novo production of viral proteins. Functional analyses of these DE proteins showed enrichment in several biological pathways including protein synthesis, cell proliferation, and T-cell activation. Importantly, these early changes before the time of robust viral production have not been described before.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2012

OPTIMAL STRATEGIES FOR CONTINUOUS GRAVITATIONAL WAVE DETECTION IN PULSAR TIMING ARRAYS

Supermassive black hole binaries (SMBHBs) are expected to emit a continuous gravitational wave signal in the pulsar timing array (PTA) frequency band (10{sup -9} to 10{sup -7} Hz). The development of data analysis techniques aimed at efficient detection and characterization of these signals is critical to the gravitational wave detection effort. In this paper, we leverage methods developed for LIGO continuous wave gravitational searches and explore the use of the F-statistic for such searches in pulsar timing data. Babak and Sesana have used this approach in the context of PTAs to show that one can resolve multiple SMBHB sources in the sky. Our work improves on several aspects of prior continuous wave search methods developed for PTA data analysis. The algorithm is implemented fully in the time domain, which naturally deals with the irregular sampling typical of PTA data and avoids spectral leakage problems associated with frequency domain methods. We take into account the fitting of the timing model and have generalized our approach to deal with both correlated and uncorrelated colored noise sources. We also develop an incoherent detection statistic that maximizes over all pulsar-dependent contributions to the likelihood. To test the effectiveness and sensitivity of our detection statistics, we perform a number of Monte Carlo simulations. We produce sensitivity curves for PTAs of various configurations and outline an implementation of a fully functional data analysis pipeline. Finally, we present a derivation of the likelihood maximized over the gravitational wave phases at the pulsar locations, which results in a vast reduction of the search parameter space.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2010

Finite size effects and scaling in solar wind fluctuations

This review highlights recent examples of generic statistical scaling as departures from ideal Kolmogorov fluid turbulence as seen in the solar wind. Similarity analysis is first reviewed to set turbulence in the context of the wider class of observed phenomenology that show statistical scaling. Examples are provided that are characteristic of finite range MHD turbulent phenomenology-anisotropy, and generalized similarity as a finite range effect. This motivates the question as to whether the observed phenomonology are universal.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2011

Boole and Bell inequality

We discuss the relation between Bell's and Boole's inequality. We apply both to the analysis of measurement results in idealized Einstein-Podolsky-Rosen-Bohm experiments. We present a local realist model that violates Bell's and Boole's inequality due to the absence of Boole's one-to-one correspondence between the two-valued variables of the mathematical description and the two-valued measurement results.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2011

Proteomic profiling revealed the functional networks associated with mitotic catastrophe of HepG2 hepatoma cells induced by 6-bromine-5-hydroxy-4-methoxybenzaldehyde

Mitotic catastrophe, a form of cell death resulting from abnormal mitosis, is a cytotoxic death pathway as well as an appealing mechanistic strategy for the development of anti-cancer drugs. In this study, 6-bromine-5-hydroxy-4-methoxybenzaldehyde was demonstrated to induce DNA double-strand break, multipolar spindles, sustain mitotic arrest and generate multinucleated cells, all of which indicate mitotic catastrophe, in human hepatoma HepG2 cells. We used proteomic profiling to identify the differentially expressed proteins underlying mitotic catastrophe. A total of 137 differentially expressed proteins (76 upregulated and 61 downregulated proteins) were identified. Some of the changed proteins have previously been associated with mitotic catastrophe, such as DNA-PKcs, FoxM1, RCC1, cyclin E, PLK1-pT210, 14-3-3{sigma} and HSP70. Multiple isoforms of 14-3-3, heat-shock proteins and tubulin were upregulated. Analysis of functional significance revealed that the 14-3-3-mediated signaling network was the most significantly enriched for the differentially expressed proteins. The modulated proteins were found to be involved in macromolecule complex assembly, cell death, cell cycle, chromatin remodeling and DNA repair, tubulin and cytoskeletal organization. These findings revealed the overall molecular events and functional signaling networks associated with spindle disruption and mitotic catastrophe. - Graphical abstract: Display Omitted Research highlights: > 6-bromoisovanillin induced spindle disruption and sustained mitotic arrest, consequently resulted in mitotic catastrophe. > Proteomic profiling identified 137 differentially expressed proteins associated mitotic catastrophe. > The 14-3-3-mediated signaling network was the most significantly enriched for the altered proteins. > The macromolecule complex assembly, cell cycle, chromatin remodeling and DNA repair, tubulin organization were also shown involved in mitotic catastrophe.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2016

Modification of chitosan membranes with nanosilica particles as polymer electrolyte membranes

Chitosan has been widely used as polymer matrix for Polymer Electrolyte Membrane (PEM) application replacing Nafion which has shortcomings in terms of high methanol permeability that degrades the performance of fuel cells. Chitosan membranes modification is performed by adding nanosilica to prevent methanol transport through the membrane. Nanosilica is synthesized by sol-gel method and the particle diameter is obtained by analysis using Breunner Emmet Teller (BET) that is 6.59 nm. Nanosilica is mixed with chitosan solution to obtain nanosilica-chitosan as polymer electrolyte membrane. The membranes are synthesized through phase inversion method with nanosilica composition including 0; 0.5; 1; 2; 3; 5; and 10% w/w of chitosan. Characterization of the membranes indicate that the results of water swelling, proton conductivity and methanol permeability of the membrane with 3% nanosilica respectively were 49.23%, 0.231 S/cm, and 5.43 x 10{sup −7} cm{sup 2}/s. Based on the results of membrane selectivity calculation, the optimum membrane is the composition of 3% nanosilica with value 5.91 x 105 S s cm{sup −3}. The results of functional groups analysis with FTIR showed that it was only physical interaction that occurred between chitosan and nanosilica since no significant changes found in peak around the wave number 1000-1250 cm{sup −-1}.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗