Office of Biological and Environmental Research Molecular Science Challenges, Workshop Report, Germantown, Maryland, May 27-29, 2014
In its Global Risks 2014 report, the World Economic Forum (WEF; WEF 2014) lists 10 current global risks of highest concern. Of these, four are science-related and all are central to the mission scope of the U.S. Department of Energy’s (DOE) Office of Biological and Environmental Research (BER): (1) water crises, (2) failure of climate change mitigation and adaptation, (3) greater incidence of extreme weather events, and (4) food crises tightly linked to the use of biomass for sustainable fuel production. The WEF report also notes the interdependencies between environmental and societal risks that make solutions to these stresses ever more important for global stability. These solutions will hinge on understanding the underlying processes of entire systems—from molecular to global scales—and will range from redesigning microbes and plants to understanding the roles of Earth’s biogeochemical systems in determining climate and contaminant transport and transformation. Clearly, however, the success of these endeavors critically depends on understanding the reliable coupling between molecular and mesoscale phenomena.